6QU2

Crystal structure of DYRK1A complexed with FC162 inhibitor

Summary for 6QU2

• Entry DOI: 10.2210/pdb6qu2/pdb
• Descriptor: Dual specificity tyrosine-phosphorylation-regulated kinase 1A, SULFATE ION, TETRAETHYLENE GLYCOL, ... (7 entities in total)
• Functional Keywords: dyrk1a, splicing kinase, kinase inhibitor, structural genomics, structural genomics consortium, sgc, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 4
• Total formula weight: 171994.15

Authors

Chaikuad, A.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Besson, T.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2019-02-26, release date: 2020-03-18, Last modification date: 2024-01-24)

• Primary citation: Chaikuad, A.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Besson, T.,Knapp, S.,Structural Genomics Consortium (SGC); Crystal structure of DYRK1A complexed with FC162 inhibitor; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.9 Å)