5F0A

CRYSTAL STRUCTURE OF PVX_084705 WITH BOUND 1-tert-butyl-3-(3-chlorophenoxy)-1H-pyrazolo[3,4-d]pyrimidin-4-amine INHIBITOR

Replaces:  4WJC

Summary for 5F0A

• Entry DOI: 10.2210/pdb5f0a/pdb
• Related: 4MYI
• Descriptor: cGMP-dependent protein kinase, putative, 1-tert-butyl-3-(3-chlorophenoxy)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (3 entities in total)
• Functional Keywords: structural genomics, structural genomics consortium, sgc, kinase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Plasmodium vivax (strain Salvador I)
• Total number of polymer chains: 1
• Total formula weight: 97044.42

Authors

Walker, J.R.,Wernimont, A.K.,He, H.,Seitova, A.,Loppnau, P.,Sibley, L.D.,Graslund, S.,Hutchinson, A.,Bountra, C.,Weigelt, J.,Edwards, A.M.,Arrowsmith, C.H.,Hui, R.,El Bakkouri, M.,Structural Genomics Consortium (SGC) (deposition date: 2015-11-27, release date: 2015-12-16, Last modification date: 2023-09-27)

• Primary citation: Walker, J.R.,Wernimont, A.K.,He, H.,Seitova, A.,Loppnau, P.,Sibley, L.D.,Graslund, S.,Hutchinson, A.,Bountra, C.,Weigelt, J.,Edwards, A.M.,Arrowsmith, C.H.,Hui, R.,El Bakkouri, M.,Structural Genomics Consortium (SGC); CRYSTAL STRUCTURE OF PVX_084705 WITH BOUND INHIBITOR; To be published,

Experimental method

X-RAY DIFFRACTION (2.6 Å)