5F0A
CRYSTAL STRUCTURE OF PVX_084705 WITH BOUND 1-tert-butyl-3-(3-chlorophenoxy)-1H-pyrazolo[3,4-d]pyrimidin-4-amine INHIBITOR
Replaces: 4WJCSummary for 5F0A
Entry DOI | 10.2210/pdb5f0a/pdb |
Related | 4MYI |
Descriptor | cGMP-dependent protein kinase, putative, 1-tert-butyl-3-(3-chlorophenoxy)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (3 entities in total) |
Functional Keywords | structural genomics, structural genomics consortium, sgc, kinase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Plasmodium vivax (strain Salvador I) |
Total number of polymer chains | 1 |
Total formula weight | 97044.42 |
Authors | Walker, J.R.,Wernimont, A.K.,He, H.,Seitova, A.,Loppnau, P.,Sibley, L.D.,Graslund, S.,Hutchinson, A.,Bountra, C.,Weigelt, J.,Edwards, A.M.,Arrowsmith, C.H.,Hui, R.,El Bakkouri, M.,Structural Genomics Consortium (SGC) (deposition date: 2015-11-27, release date: 2015-12-16, Last modification date: 2023-09-27) |
Primary citation | Walker, J.R.,Wernimont, A.K.,He, H.,Seitova, A.,Loppnau, P.,Sibley, L.D.,Graslund, S.,Hutchinson, A.,Bountra, C.,Weigelt, J.,Edwards, A.M.,Arrowsmith, C.H.,Hui, R.,El Bakkouri, M.,Structural Genomics Consortium (SGC) CRYSTAL STRUCTURE OF PVX_084705 WITH BOUND INHIBITOR To be published, |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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