6W5G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6w5g by Molmil](/molmil-images/mine/6w5g) | Class D beta-lactamase BAT-2 | 分子名称: | 1,2-ETHANEDIOL, BAT-2 beta-lactamase | 著者 | Smith, C.A, Vakulenko, S.B, Stewart, N.K, Toth, M. | 登録日 | 2020-03-13 | 公開日 | 2020-06-24 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.451 Å) | 主引用文献 | A surface loop modulates activity of the Bacillus class D beta-lactamases. J.Struct.Biol., 211, 2020
|
|
1JY5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jy5 by Molmil](/molmil-images/mine/1jy5) | RNase-related protein from Calystegia sepium | 分子名称: | CalsepRRP | 著者 | Rabijns, A, Verboven, C, Rouge, P, Barre, A, Van Damme, E.J.M, Peumans, W.J, De Ranter, C.J. | 登録日 | 2001-09-11 | 公開日 | 2002-04-10 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structure of an RNase-related protein from Calystegia sepium. Acta Crystallogr.,Sect.D, 58, 2002
|
|
6W5Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6w5q by Molmil](/molmil-images/mine/6w5q) | Structure of the globular C-terminal domain of P. aeruginosa LpoP | 分子名称: | Peptidoglycan synthase activator LpoP, SULFATE ION, TRIETHYLENE GLYCOL | 著者 | Caveney, N.A, Robb, C.S, Simorre, J.P, Strynadka, N.C.J. | 登録日 | 2020-03-13 | 公開日 | 2020-05-06 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of the Peptidoglycan Synthase Activator LpoP in Pseudomonas aeruginosa. Structure, 28, 2020
|
|
2W8J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2w8j by Molmil](/molmil-images/mine/2w8j) | SPT with PLP-ser | 分子名称: | SERINE PALMITOYLTRANSFERASE, [3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-SERINE | 著者 | Carter, L.G, Raman, M.C.C, Johnson, K.A, Campopiano, D.J, Naismith, J.H. | 登録日 | 2009-01-16 | 公開日 | 2009-01-27 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | The External-Aldimine Form of Serine Palmitoyltranserase; Structural, Kinetic and Spectroscopic Analysis of the Wild-Type Enzyme and Hsan1 Mutant Mimics. J.Biol.Chem., 284, 2009
|
|
8A0C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8a0c by Molmil](/molmil-images/mine/8a0c) | Capsular polysaccharide synthesis multienzyme in complex with CMP | 分子名称: | Bcs3, CYTIDINE-5'-MONOPHOSPHATE, GLYCEROL, ... | 著者 | Cifuente, J.O, Schulze, J, Bethe, A, Di Domenico, V, Litschko, C, Budde, I, Eidenberger, L, Thiesler, H, Ramon-Roth, I, Berger, M, Claus, H, DAngelo, C, Marina, A, Gerardy-Schahn, R, Schubert, M, Guerin, M.E, Fiebig, T. | 登録日 | 2022-05-27 | 公開日 | 2023-04-26 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | A multi-enzyme machine polymerizes the Haemophilus influenzae type b capsule. Nat.Chem.Biol., 19, 2023
|
|
8A0M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8a0m by Molmil](/molmil-images/mine/8a0m) | Capsular polysaccharide synthesis multienzyme in complex with capsular polymer fragment | 分子名称: | Bcs3, MAGNESIUM ION, beta-D-ribosyl-(1->1)-D-ribitol-5-phosphate | 著者 | Cifuente, J.O, Schulze, J, Bethe, A, Di Domenico, V, Litschko, C, Budde, I, Eidenberger, L, Thiesler, H, Ramon-Roth, I, Berger, M, Claus, H, DAngelo, C, Marina, A, Gerardy-Schahn, R, Schubert, M, Guerin, M.E, Fiebig, T. | 登録日 | 2022-05-29 | 公開日 | 2023-04-26 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | A multi-enzyme machine polymerizes the Haemophilus influenzae type b capsule. Nat.Chem.Biol., 19, 2023
|
|
5DFD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5dfd by Molmil](/molmil-images/mine/5dfd) | Crystal structure of BRD2(BD2) W370F mutant with ligand 28 bound | 分子名称: | Bromodomain-containing protein 2, GLYCEROL, methyl [(4S)-6-(1H-indol-4-yl)-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl]acetate | 著者 | Tallant, C, Baud, M, Lin-Shiao, E, Chirgadze, D.Y, Ciulli, A. | 登録日 | 2015-08-26 | 公開日 | 2015-11-11 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | New Synthetic Routes to Triazolo-benzodiazepine Analogues: Expanding the Scope of the Bump-and-Hole Approach for Selective Bromo and Extra-Terminal (BET) Bromodomain Inhibition. J.Med.Chem., 59, 2016
|
|
1JO8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jo8 by Molmil](/molmil-images/mine/1jo8) | Structural analysis of the yeast actin binding protein Abp1 SH3 domain | 分子名称: | ACTIN BINDING PROTEIN, SULFATE ION | 著者 | Fazi, B, Cope, M.J, Douangamath, A, Ferracuti, S, Schirwitz, K, Zucconi, A, Drubin, D.G, Wilmanns, M, Cesareni, G, Castagnoli, L. | 登録日 | 2001-07-27 | 公開日 | 2002-03-01 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Unusual binding properties of the SH3 domain of the yeast actin-binding protein Abp1: structural and functional analysis. J.Biol.Chem., 277, 2002
|
|
5URW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5urw by Molmil](/molmil-images/mine/5urw) | |
2VW6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2vw6 by Molmil](/molmil-images/mine/2vw6) | NITRITE REDUCTASE FROM ALCALIGENES XYLOSOXIDANS - 3 OF 3 | 分子名称: | COPPER (II) ION, DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE, TETRAETHYLENE GLYCOL, ... | 著者 | Ellis, M.J, Buffey, S.G, Hough, M.A, Hasnain, S.S. | 登録日 | 2008-06-16 | 公開日 | 2008-09-09 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | On-Line Optical and X-Ray Spectroscopies with Crystallography: An Integrated Approach for Determining Metalloprotein Structures in Functionally Well Defined States. J.Synchrotron Radiat., 15, 2008
|
|
3ZUH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3zuh by Molmil](/molmil-images/mine/3zuh) | Negative stain EM Map of the AAA protein CbbX, a red-type Rubisco activase from R. sphaeroides | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, PROTEIN CBBX, RIBULOSE-1,5-DIPHOSPHATE | 著者 | Mueller-Cajar, O, Stotz, M, Wendler, P, Hartl, F.U, Bracher, A, Hayer-Hartl, M. | 登録日 | 2011-07-19 | 公開日 | 2011-11-09 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (21 Å) | 主引用文献 | Structure and Function of the Aaa+ Protein Cbbx, a Red-Type Rubisco Activase. Nature, 479, 2011
|
|
5K95
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5k95 by Molmil](/molmil-images/mine/5k95) | |
4QUU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4quu by Molmil](/molmil-images/mine/4quu) | Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) complexed with Histone H4-K(ac)5 | 分子名称: | 1,2-ETHANEDIOL, ATPase family AAA domain-containing protein 2, Histone H4, ... | 著者 | Chaikuad, A, Felletar, I, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2014-07-12 | 公開日 | 2014-07-30 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Atad2 is a generalist facilitator of chromatin dynamics in embryonic stem cells. J Mol Cell Biol, 8, 2016
|
|
2IXT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ixt by Molmil](/molmil-images/mine/2ixt) | SPHERICASE | 分子名称: | 36KDA PROTEASE, CALCIUM ION | 著者 | Almog, O, Gonzalez, A, Godin, N. | 登録日 | 2006-07-11 | 公開日 | 2007-08-21 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (0.8 Å) | 主引用文献 | The Crystal Structures of the Psychrophilic Subtilisin S41 and the Mesophilic Subtilisin Sph Reveal the Same Calcium-Loaded State. Proteins, 74, 2009
|
|
5CY0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5cy0 by Molmil](/molmil-images/mine/5cy0) | Total Chemical Synthesis, Covalent Structure Verification, and X-ray Structure of Bioactive Ts3 Toxin by Racemic Protein Crystallography | 分子名称: | GLYCEROL, Ts3 Toxin | 著者 | Dang, B, Kubota, T, Mandal, K, Correa, A.M, Bezanilla, F, Kent, S.B. | 登録日 | 2015-07-29 | 公開日 | 2016-06-01 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Elucidation of the Covalent and Tertiary Structures of Biologically Active Ts3 Toxin. Angew.Chem.Int.Ed.Engl., 55, 2016
|
|
7ZKB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7zkb by Molmil](/molmil-images/mine/7zkb) | ABCB1 V978C mutant (mABCB1) in the inward facing state | 分子名称: | (4S,11S,18S)-4-[[(2,4-dinitrophenyl)disulfanyl]methyl]-11,18-dimethyl-6,13,20-trithia-3,10,17,22,23,24-hexazatetracyclo[17.2.1.1^{5,8}.1^{12,15}]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione, (4~{S},11~{S},18~{S})-4,11-dimethyl-18-(sulfanylmethyl)-6,13,20-trithia-3,10,17,22,23,24-hexazatetracyclo[17.2.1.1^{5,8}.1^{12,15}]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione, ATP-dependent translocase ABCB1 | 著者 | Parey, K, Januliene, D, Gewering, T, Moeller, A. | 登録日 | 2022-04-12 | 公開日 | 2023-04-26 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | Tracing the substrate translocation mechanism in P-glycoprotein. Elife, 12, 2024
|
|
2IX1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ix1 by Molmil](/molmil-images/mine/2ix1) | RNase II D209N mutant | 分子名称: | 5'-D(*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP *AP*AP*A)-3', EXORIBONUCLEASE 2, MAGNESIUM ION | 著者 | Frazao, C, McVey, C.E, Amblar, M, Barbas, A, Vonrhein, C, Arraiano, C.M, Carrondo, M.A. | 登録日 | 2006-07-05 | 公開日 | 2006-10-05 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | 主引用文献 | Unravelling the Dynamics of RNA Degradation by Ribonuclease II and its RNA-Bound Complex Nature, 443, 2006
|
|
6PPS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pps by Molmil](/molmil-images/mine/6pps) | A blue light illuminated LOV-PAS construct from the LOV-HK sensory protein from Brucella abortus (construct 15-273) | 分子名称: | Blue-light-activated histidine kinase, FLAVIN MONONUCLEOTIDE | 著者 | Rinaldi, J, Fernandez, I, Shin, H, Gunawardana, S, Otero, L.H, Cerutti, M.L, Yang, X, Klinke, S, Goldbaum, F.A. | 登録日 | 2019-07-08 | 公開日 | 2020-07-15 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Dimer Asymmetry and Light Activation Mechanism in Brucella Blue-Light Sensor Histidine Kinase. Mbio, 12, 2021
|
|
5KCD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5kcd by Molmil](/molmil-images/mine/5kcd) | Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with an N-methyl Substituted OBHS-N derivative | 分子名称: | (1S,2R,4S)-5,6-bis(4-hydroxyphenyl)-N-methyl-N-phenyl-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide, Estrogen receptor, NCOA2 | 著者 | Nwachukwu, J.C, Srinivasan, S, Bruno, N.E, Dharmarajan, V, Goswami, D, Kastrati, I, Novick, S, Nowak, J, Zhou, H.B, Boonmuen, N, Zhao, Y, Min, J, Frasor, J, Katzenellenbogen, B.S, Griffin, P.R, Katzenellenbogen, J.A, Nettles, K.W. | 登録日 | 2016-06-06 | 公開日 | 2016-11-16 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Full antagonism of the estrogen receptor without a prototypical ligand side chain. Nat. Chem. Biol., 13, 2017
|
|
7B2I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7b2i by Molmil](/molmil-images/mine/7b2i) | Heterodimeric tRNA-Guanine Transglycosylase from mouse | 分子名称: | CITRIC ACID, DI(HYDROXYETHYL)ETHER, HEXAETHYLENE GLYCOL, ... | 著者 | Sebastiani, M, Heine, A, Reuter, K. | 登録日 | 2020-11-27 | 公開日 | 2021-12-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural and Biochemical Investigation of the Heterodimeric Murine tRNA-Guanine Transglycosylase. Acs Chem.Biol., 17, 2022
|
|
5V2K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5v2k by Molmil](/molmil-images/mine/5v2k) | Crystal structure of UDP-glucosyltransferase, UGT74F2 (T15A), with UDP and 2-bromobenzoic acid | 分子名称: | 2-bromobenzoic acid, UDP-glycosyltransferase 74F2, URIDINE-5'-DIPHOSPHATE, ... | 著者 | George Thompson, A.M, Iancu, C.V, Dean, J.V, Choe, J. | 登録日 | 2017-03-04 | 公開日 | 2017-05-03 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.002 Å) | 主引用文献 | Differences in salicylic acid glucose conjugations by UGT74F1 and UGT74F2 from Arabidopsis thaliana. Sci Rep, 7, 2017
|
|
6PRG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6prg by Molmil](/molmil-images/mine/6prg) | SBP RafE in complex with stachyose | 分子名称: | 1,2-ETHANEDIOL, ABC transporter sugar-binding protein, CITRIC ACID, ... | 著者 | Meier, E.P.W, Boraston, A.B. | 登録日 | 2019-07-10 | 公開日 | 2019-10-02 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Molecular analysis of an enigmaticStreptococcus pneumoniaevirulence factor: The raffinose-family oligosaccharide utilization system. J.Biol.Chem., 294, 2019
|
|
4IKU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4iku by Molmil](/molmil-images/mine/4iku) | Crystal structure of truncated (delta 1-89) human methionine aminopeptidase Type 1 in complex with 2-((5-chloro-6-methyl-2-(pyridin-2-yl)pyrimidin-4-yl)amino)-3-phenylpropanamide | 分子名称: | COBALT (II) ION, Methionine aminopeptidase 1, Nalpha-[5-chloro-6-methyl-2-(pyridin-2-yl)pyrimidin-4-yl]-D-phenylalaninamide, ... | 著者 | Addlagatta, A, Kishor, C, Arya, T. | 登録日 | 2012-12-28 | 公開日 | 2013-12-11 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Identification, Biochemical and Structural Evaluation of Species-Specific Inhibitors against Type I Methionine Aminopeptidases J.Med.Chem., 56, 2013
|
|
1JVO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jvo by Molmil](/molmil-images/mine/1jvo) | Azurin dimer, crosslinked via disulfide bridge | 分子名称: | Azurin, COPPER (II) ION | 著者 | van Amsterdam, I.M.C, Ubbink, M, Einsle, O, Messerschmidt, A, Merli, A, Cavazzini, D, Rossi, G.L, Canters, G.W. | 登録日 | 2001-08-30 | 公開日 | 2002-01-04 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Dramatic modulation of electron transfer in protein complexes by crosslinking Nat.Struct.Biol., 9, 2002
|
|
3X2S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3x2s by Molmil](/molmil-images/mine/3x2s) | Crystal structure of pyrene-conjugated adenylate kinase | 分子名称: | Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, MAGNESIUM ION, ... | 著者 | Fujii, A, Sekiguchi, Y, Matsumura, H, Inoue, T, Chung, W.-S, Hirota, S, Matsuo, T. | 登録日 | 2014-12-31 | 公開日 | 2015-04-01 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Excimer Emission Properties on Pyrene-Labeled Protein Surface: Correlation between Emission Spectra, Ring Stacking Modes, and Flexibilities of Pyrene Probes. Bioconjug.Chem., 26, 2015
|
|