5KUW
| Human cyclophilin A at 100K, Data set 9 | 分子名称: | Peptidyl-prolyl cis-trans isomerase A | 著者 | Russi, S, Gonzalez, A, Kenner, L.R, Keedy, D.A, Fraser, J.S, van den Bedem, H. | 登録日 | 2016-07-13 | 公開日 | 2016-08-10 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Conformational variation of proteins at room temperature is not dominated by radiation damage. J Synchrotron Radiat, 24, 2017
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6C1H
| High-Resolution Cryo-EM Structures of Actin-bound Myosin States Reveal the Mechanism of Myosin Force Sensing | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Mentes, A, Huehn, A, Liu, X, Zwolak, A, Dominguez, R, Shuman, H, Ostap, E.M, Sindelar, C.V. | 登録日 | 2018-01-04 | 公開日 | 2018-01-31 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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7SV9
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5KV5
| Human cyclophilin A at 278K, Data set 7 | 分子名称: | Peptidyl-prolyl cis-trans isomerase A | 著者 | Russi, S, Gonzalez, A, Kenner, L.R, Keedy, D.A, Fraser, J.S, van den Bedem, H. | 登録日 | 2016-07-13 | 公開日 | 2016-08-10 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Conformational variation of proteins at room temperature is not dominated by radiation damage. J Synchrotron Radiat, 24, 2017
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8CG7
| Structure of p53 cancer mutant Y220C with arylation at Cys182 and Cys277 | 分子名称: | 1,2-ETHANEDIOL, 5-iodanyl-2-methylsulfonyl-pyrimidine, Cellular tumor antigen p53, ... | 著者 | Balourdas, D.I, Pichon, M.M, Baud, M.G.J, Knapp, S, Joerger, A.C, Structural Genomics Consortium (SGC) | 登録日 | 2023-02-03 | 公開日 | 2023-12-13 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | Structure-Reactivity Studies of 2-Sulfonylpyrimidines Allow Selective Protein Arylation. Bioconjug.Chem., 34, 2023
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7T00
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6NTL
| Crystal Structure of Recombinant Human Acetylcholinesterase Inhibited by A-234 | 分子名称: | 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase, ... | 著者 | Bester, S.M, Guelta, M.A, Height, J.J, Pegan, S.D. | 登録日 | 2019-01-29 | 公開日 | 2020-07-01 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Insights into inhibition of human acetylcholinesterase by Novichok, A-series Nerve Agents To Be Published
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6FYS
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8POG
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4FNJ
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6C4A
| Crystal structure of 3-nitropropionate modified isocitrate lyase from Mycobacterium tuberculosis with pyruvate | 分子名称: | 3-NITROPROPANOIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... | 著者 | Kreitler, D.F, Ray, S, Murkin, A.S, Gulick, A.M. | 登録日 | 2018-01-11 | 公開日 | 2018-06-06 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The Nitro Group as a Masked Electrophile in Covalent Enzyme Inhibition. ACS Chem. Biol., 13, 2018
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8CB5
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8POC
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7SP3
| E. coli RppH bound to Ap4A | 分子名称: | BIS(ADENOSINE)-5'-TETRAPHOSPHATE, CHLORIDE ION, FLUORIDE ION, ... | 著者 | Serganov, A.A, Vasilyev, N, Nuthanakanti, A. | 登録日 | 2021-11-02 | 公開日 | 2022-03-09 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | A distinct RNA recognition mechanism governs Np 4 decapping by RppH. Proc.Natl.Acad.Sci.USA, 119, 2022
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8VIL
| EgtB-IV from Crocosphaera subtropica, an ergothioneine-biosynthetic type IV sulfoxide synthase in complex with N,N-dimethyl-histidine | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, FE (III) ION, ... | 著者 | Ireland, K.A, Davis, K.M. | 登録日 | 2024-01-04 | 公開日 | 2024-08-07 | 最終更新日 | 2024-09-11 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural insights into the convergent evolution of sulfoxide synthase EgtB-IV, an ergothioneine-biosynthetic homolog of ovothiol synthase OvoA. Structure, 2024
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8VIH
| EgtB-IV from Crocosphaera subtropica, an ergothioneine-biosynthetic type IV sulfoxide synthase in complex with hercynine | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, FE (III) ION, ... | 著者 | Ireland, K.A, Davis, K.M. | 登録日 | 2024-01-04 | 公開日 | 2024-08-07 | 最終更新日 | 2024-09-11 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structural insights into the convergent evolution of sulfoxide synthase EgtB-IV, an ergothioneine-biosynthetic homolog of ovothiol synthase OvoA. Structure, 2024
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5MQG
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8CMT
| Structure of the plasma coagulation Factor XIII A2B2 heterotetrameric complex. | 分子名称: | Coagulation factor XIII A chain, Coagulation factor XIII B chain | 著者 | Singh, S, Ugurlar, D, Hagelueken, G, Geyer, M, Biswas, A. | 登録日 | 2023-02-21 | 公開日 | 2024-09-11 | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | 主引用文献 | The cryo-EM structure of plasma coagulation Factor XIII heterotetrameric complex at 2.68 Angstrom resolution. To Be Published
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4ZT1
| Crystal structure of human E-Cadherin (residues 3-213) in x-dimer conformation | 分子名称: | CALCIUM ION, Cadherin-1 | 著者 | Nardone, V, Lucarelli, A.P, Dalle Vedove, A, Parisini, E. | 登録日 | 2015-05-14 | 公開日 | 2016-06-01 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Crystal Structure of Human E-Cadherin-EC1EC2 in Complex with a Peptidomimetic Competitive Inhibitor of Cadherin Homophilic Interaction. J.Med.Chem., 59, 2016
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6TLL
| HUMAN CK2 KINASE ALPHA SUBUNIT IN COMPLEX WITH THE ATP-COMPETITIVE INHIBITOR 4,5,6,7-TETRABROMOBENZOTRIAZOLE (tBBT) | 分子名称: | 4,5,6,7-TETRABROMOBENZOTRIAZOLE, CHLORIDE ION, Casein kinase II subunit alpha, ... | 著者 | Czapinska, H, Piasecka, A, Winiewska-Szajewska, M, Bochtler, M, Poznanski, J. | 登録日 | 2019-12-03 | 公開日 | 2020-12-16 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Halogen Atoms in the Protein-Ligand System. Structural and Thermodynamic Studies of the Binding of Bromobenzotriazoles by the Catalytic Subunit of Human Protein Kinase CK2. J.Phys.Chem.B, 125, 2021
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6W2B
| Anomalous bromine signal reveals the position of Br-paroxetine complexed with the serotonin transporter at the central site | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 8B6 heavy chain antibody fragment, 8B6 light chain antibody fragment, ... | 著者 | Coleman, J.A, Navratna, V, Yang, D. | 登録日 | 2020-03-05 | 公開日 | 2020-03-25 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (4.7 Å) | 主引用文献 | Chemical and structural investigation of the paroxetine-human serotonin transporter complex. Elife, 9, 2020
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6QY9
| Human CSNK2A2 bound to a Pyrrolo[2,3-d]pyrimidinyl inhibitor | 分子名称: | 1,2-ETHANEDIOL, 3-[3-[2-[(3,4,5-trimethoxyphenyl)amino]pyrrolo[2,3-d]pyrimidin-7-yl]phenyl]propanenitrile, CHLORIDE ION, ... | 著者 | Abdul Azeez, K.R, Sorrell, F.J, Krojer, T, Bountra, C, Edwards, A.M, Arrowsmith, C, Knapp, S, Elkins, J.M. | 登録日 | 2019-03-08 | 公開日 | 2019-04-17 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Human CSNK2A2 bound to a Pyrrolo[2,3-d]pyrimidinyl inhibitor To Be Published
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7SSU
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8A7P
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6BIT
| SIRPalpha antibody complex | 分子名称: | KWAR23 Fab heavy chain, KWAR23 Fab light chain, Tyrosine-protein phosphatase non-receptor type substrate 1 | 著者 | Ring, N.G, Herndler-Brandstetter, D, Weiskopf, K, Shan, L, Volkmer, J.P, George, B.M, Lietzenmayer, M, McKenna, K.M, Naik, T.J, McCarty, A, Zheng, Y, Ring, A.M, Flavell, R.A, Weissman, I.L. | 登録日 | 2017-11-03 | 公開日 | 2017-12-06 | 最終更新日 | 2019-11-20 | 実験手法 | X-RAY DIFFRACTION (2.191 Å) | 主引用文献 | Anti-SIRP alpha antibody immunotherapy enhances neutrophil and macrophage antitumor activity. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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