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PDB: 89832 件

8BOE
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Human Carbonic Anhydrase I in complex with (S)-4-(3-(1-(6-nitropyridin-2-yl)pyrrolidin-3-yl)thioureido)benzenesulfonamide
分子名称: 1-[(3~{R})-1-(6-nitropyridin-2-yl)pyrrolidin-3-yl]-3-(4-sulfamoylphenyl)thiourea, Carbonic anhydrase 2, GLYCEROL, ...
著者Angeli, A, Ferraroni, M.
登録日2022-11-15
公開日2023-11-29
最終更新日2024-06-12
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献First-in-Class Dual Hybrid Carbonic Anhydrase Inhibitors and Transient Receptor Potential Vanilloid 1 Agonists Revert Oxaliplatin-Induced Neuropathy.
J.Med.Chem., 66, 2023
2K0B
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NMR structure of the UBA domain of p62 (SQSTM1)
分子名称: Sequestosome-1
著者Long, J.E, Ciani, B, Gallagher, T.R.A, Cavey, J.R, Sheppard, P.W, Layfield, R, Searle, M.S.
登録日2008-01-31
公開日2008-02-19
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Conformation and dynamics of the three-helix bundle UBA domain of p62 from experiment and simulation.
Proteins, 71, 2007
8EIS
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Cryo-EM structure of octopus sensory receptor CRT1
分子名称: 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Octopus sensory receptor
著者Kang, G, Kim, J.J, Allard, C.A.H, Valencia-Montoya, W.A, Bellono, N.W, Hibbs, R.E.
登録日2022-09-15
公開日2023-04-12
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (2.62 Å)
主引用文献Sensory specializations drive octopus and squid behaviour.
Nature, 616, 2023
4YXD
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CRYSTAL STRUCTURE OF PORCINE HEART MITOCHONDRIAL COMPLEX II BOUND WITH flutolanil
分子名称: FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Harada, S, Shiba, T, Sato, D, Yamamoto, A, Nagahama, M, Yone, A, Inaoka, D.K, Sakamoto, K, Inoue, M, Honma, T, Kita, K.
登録日2015-03-23
公開日2016-03-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria
Int J Mol Sci, 16, 2015
1QWI
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Crystal Structure of E. coli OsmC
分子名称: osmotically inducible protein
著者Lesniak, J, Barton, W.A, Nikolov, D.B.
登録日2003-09-02
公開日2003-12-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and functional features of the Escherichia coli hydroperoxide resistance protein OsmC
Protein Sci., 12, 2003
6U5Z
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Cryo-EM structure of E. coli LonA S679A
分子名称: Lon protease
著者Botos, I, Lountos, G.T, Weimin, W, Wlodawer, A.
登録日2019-08-28
公開日2020-02-26
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structure of substrate-free E. coli Lon protease provides insights into the dynamics of Lon machinery
Curr Res Struct Biol, 1, 2020
8VJB
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Cryo-EM structure of short form insulin receptor (IR-A) with four IGF2 bound, symmetric conformation.
分子名称: Insulin-like growth factor II, Isoform Short of Insulin receptor
著者An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E.
登録日2024-01-06
公開日2024-03-27
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Activation of the insulin receptor by insulin-like growth factor 2.
Nat Commun, 15, 2024
6Z1E
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Crystal structure of the AAA domain of Rubisco Activase from Nostoc sp. (strain PCC 7120)
分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Ribulose bisphosphate carboxylase/oxygenase activase
著者Popilka, L, Bracher, A.
登録日2020-05-13
公開日2020-09-23
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.454 Å)
主引用文献Dual Functions of a Rubisco Activase in Metabolic Repair and Recruitment to Carboxysomes.
Cell, 183, 2020
5OAV
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High resolution crystal structure of the c-Src-SH3 domain mutant E93V in complex with the high affinity synthetic peptide APP12: monoclinic crystal
分子名称: APP12, Proto-oncogene tyrosine-protein kinase Src
著者Camara-Artigas, A.
登録日2017-06-23
公開日2017-07-12
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (0.95 Å)
主引用文献High resolution crystal structure of the c-Src-SH3 domain mutant E93V in complex with the high affinity synthetic peptide APP12: monoclinic crystal
to be published
1FCO
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CRYSTAL STRUCTURE OF THE E. COLI AMPC BETA-LACTAMASE COVALENTLY ACYLATED WITH THE INHIBITORY BETA-LACTAM, MOXALACTAM
分子名称: (2R)-2-[(1R)-1-{[(2S)-2-carboxy-2-(4-hydroxyphenyl)acetyl]amino}-1-methoxy-2-oxoethyl]-5-methylidene-5,6-dihydro-2H-1,3-oxazine-4-carboxylic acid, BETA-LACTAMASE
著者Patera, A, Blaszczak, L.C, Shoichet, B.K.
登録日2000-07-19
公開日2000-12-04
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structures of Substrate and Inhibitor Complexes with AmpC -Lactamase: Possible Implications for Substrate-Assisted Catalysis
J.Am.Chem.Soc., 122, 2000
7S6I
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BU of 7s6i by Molmil
SARS-CoV-2-6P-Mut2 S protein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Ozorowski, G, Torres, J.L, Ward, A.B.
登録日2021-09-14
公開日2022-05-11
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody.
Proc.Natl.Acad.Sci.USA, 119, 2022
7S6L
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J08 fragment antigen binding in complex with SARS-CoV-2-6P-Mut7 S protein (conformation 3)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, J08 fragment antigen binding heavy chain variable domain, ...
著者Ozorowski, G, Torres, J.L, Ward, A.B.
登録日2021-09-14
公開日2022-05-11
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody.
Proc.Natl.Acad.Sci.USA, 119, 2022
7S6K
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J08 fragment antigen binding in complex with SARS-CoV-2-6P-Mut2 S protein (conformation 2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, J08 fragment antigen binding heavy chain variable domain, ...
著者Ozorowski, G, Torres, J.L, Ward, A.B.
登録日2021-09-14
公開日2022-05-11
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody.
Proc.Natl.Acad.Sci.USA, 119, 2022
3BD7
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BU of 3bd7 by Molmil
Glycogen Phosphorylase complex with 1(-D-glucopyranosyl) thymine
分子名称: 1-beta-D-glucopyranosyl-5-methylpyrimidine-2,4(1H,3H)-dione, Glycogen phosphorylase, muscle form, ...
著者Sovantzis, D.A, Hadjiloi, T, Hayes, J.M, Zographos, S.E, Chrysina, E.D, Oikonomakos, N.G.
登録日2007-11-14
公開日2008-11-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献D-Glucopyranosyl pyrimidine nucleoside binding to muscle glycogen phosphorylase b
To be Published
7S6J
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BU of 7s6j by Molmil
J08 fragment antigen binding in complex with SARS-CoV-2-6P-Mut2 S protein (conformation 1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, J08 fragment antigen binding heavy chain variable domain, ...
著者Ozorowski, G, Torres, J.L, Ward, A.B.
登録日2021-09-14
公開日2022-05-11
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody.
Proc.Natl.Acad.Sci.USA, 119, 2022
8VJC
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Cryo-EM structure of short form insulin receptor (IR-A) with three IGF2 bound, asymmetric conformation.
分子名称: Insulin-like growth factor II, Isoform Short of Insulin receptor
著者An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E.
登録日2024-01-06
公開日2024-03-27
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Activation of the insulin receptor by insulin-like growth factor 2.
Nat Commun, 15, 2024
4AMT
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BU of 4amt by Molmil
Crystal structure at 2.6A of human prorenin
分子名称: RENIN, SULFATE ION, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
著者Zhou, A.
登録日2012-03-13
公開日2013-03-20
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The Crystal Structure of Prorenin
To be Published
8S4T
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DNA bound structure of PrgE from plasmid pCF10
分子名称: DNA, PrgE, TRIETHYLENE GLYCOL
著者Breidenstein, A, Berntsson, R.P.-A.
登録日2024-02-22
公開日2024-05-29
最終更新日2024-07-03
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献PrgE: an OB-fold protein from plasmid pCF10 with striking differences to prototypical bacterial SSBs.
Life Sci Alliance, 7, 2024
7N82
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BU of 7n82 by Molmil
NMR Solution structure of Se0862
分子名称: Biofilm-related protein
著者Zhang, N, LiWang, A.L.
登録日2021-06-11
公開日2021-07-14
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Assessment of prediction methods for protein structures determined by NMR in CASP14: Impact of AlphaFold2.
Proteins, 89, 2021
8VRJ
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Rigid body fitted model for gamma tubulin ring complex capped microtubule
分子名称: Actin, cytoplasmic 1, Gamma-tubulin complex component 3, ...
著者Aher, A, Urnavicius, L, Kapoor, T.M.
登録日2024-01-22
公開日2024-03-27
最終更新日2024-07-31
実験手法ELECTRON MICROSCOPY (7.7 Å)
主引用文献Structure of the gamma-tubulin ring complex-capped microtubule.
Nat.Struct.Mol.Biol., 31, 2024
7SCX
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BU of 7scx by Molmil
KRAS full-length G12V in complex with RGL1 Ras association domain
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Isoform 2B of GTPase KRas, MAGNESIUM ION, ...
著者Eves, B.J, Kuntz, D.A, Ikura, M, Marshall, C.B.
登録日2021-09-29
公開日2022-05-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Structures of RGL1 RAS-Association Domain in Complex with KRAS and the Oncogenic G12V Mutant.
J.Mol.Biol., 434, 2022
8VRK
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Rigid body fitted model for refined density map of gamma tubulin ring complex capped microtubule
分子名称: Actin, cytoplasmic 1, Gamma-tubulin complex component 3, ...
著者Aher, A, Urnavicius, L, Kapoor, T.M.
登録日2024-01-22
公開日2024-03-27
最終更新日2024-07-31
実験手法ELECTRON MICROSCOPY (8.5 Å)
主引用文献Structure of the gamma-tubulin ring complex-capped microtubule.
Nat.Struct.Mol.Biol., 31, 2024
1M4U
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Crystal structure of Bone Morphogenetic Protein-7 (BMP-7) in complex with the secreted antagonist Noggin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Bone Morphogenetic Protein-7, Noggin
著者Groppe, J, Greenwald, J, Wiater, E, Rodriguez-Leon, J, Economides, A.N, Kwiatkowski, W, Affolter, M, Vale, W.W, Izpisua-Belmonte, J.C, Choe, S.
登録日2002-07-03
公開日2002-12-18
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Structural Basis of BMP Signalling Inhibition by the Cystine Knot Protein Noggin
Nature, 420, 2002
7K18
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Cardiac Sodium channel with toxin bound
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-like toxin Lqh3, ...
著者Jiang, D, Catterall, W.A.
登録日2020-09-07
公開日2021-01-20
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis for voltage-sensor trapping of the cardiac sodium channel by a deathstalker scorpion toxin.
Nat Commun, 12, 2021
8QXO
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Cryo-EM structure of tetrameric human SAMHD1 State V - Depleted relaxed
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ...
著者Acton, O.J, Sheppard, D, Rosenthal, P.B, Taylor, I.A.
登録日2023-10-24
公開日2024-05-15
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.43 Å)
主引用文献Platform-directed allostery and quaternary structure dynamics of SAMHD1 catalysis.
Nat Commun, 15, 2024

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