8E2X
 
 | | Purification of Enterovirus A71, strain 4643, WT capsid | | 分子名称: | SPHINGOSINE, VP1, VP2, ... | | 著者 | Catching, A, Capponi, S, Andino, R. | | 登録日 | 2022-08-16 | | 公開日 | 2023-08-30 | | 最終更新日 | 2023-12-06 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | A tradeoff between enterovirus A71 particle stability and cell entry.
Nat Commun, 14, 2023
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7RP0
 | | Structural Snapshots of Intermediates in the Gating of a K+ Channel | | 分子名称: | DIACYL GLYCEROL, KcsA Fab chain A, KcsA Fab chain B, ... | | 著者 | Reddi, R, Matulef, K, Riederer, E.A, Valiyaveetil, F.I. | | 登録日 | 2021-08-02 | | 公開日 | 2021-10-27 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Structures of Gating Intermediates in a K + channell.
J.Mol.Biol., 433, 2021
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8E3C
 | | Purification of Enterovirus A71, strain 4643, WT capsid | | 分子名称: | VP1, VP2, VP3 | | 著者 | Catching, A, Capponi, S, Andino, R. | | 登録日 | 2022-08-16 | | 公開日 | 2023-08-30 | | 最終更新日 | 2023-12-06 | | 実験手法 | ELECTRON MICROSCOPY (7.1 Å) | | 主引用文献 | A tradeoff between enterovirus A71 particle stability and cell entry.
Nat Commun, 14, 2023
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6YGR
 | | tRNA-guanine Transglycosylase (TGT) in co-crystallized complex with 6-Amino-4-(2-phenylethyl)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one | | 分子名称: | 6-AMINO-4-(2-PHENYLETHYL)-1,7-DIHYDRO-8H-IMIDAZO[4,5-G]QUINAZOLIN-8-ONE, Queuine tRNA-ribosyltransferase, ZINC ION | | 著者 | Nguyen, A, Heine, A, Klebe, G. | | 登録日 | 2020-03-27 | | 公開日 | 2020-04-08 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Co-crystallization and nanoESI-MS reveal dimer disturbing inhibitors and conformational changes at dimer contacts
To Be Published
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8B05
 | | TRYPTOPHAN SYNTHASE - Cryo-trapping by the spitrobot crystal plunger after 20 sec | | 分子名称: | CESIUM ION, CHLORIDE ION, INDOLE, ... | | 著者 | Mehrabi, P, Sung, S, von Stetten, D, Prester, A, Hatton, C.E, Kleine-Dopke, S, Berkes, A, Gore, G, Leimkohl, J.P, Schikora, H, Kollewe, M, Rohde, H, Wilmanns, M, Tellkamp, F, Schulz, E.C. | | 登録日 | 2022-09-07 | | 公開日 | 2023-05-03 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Millisecond cryo-trapping by the spitrobot crystal plunger simplifies time-resolved crystallography.
Nat Commun, 14, 2023
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8E38
 | | Purification of Enterovirus A71, strain 4643, WT capsid | | 分子名称: | SPHINGOSINE, VP1, VP2, ... | | 著者 | Catching, A, Capponi, S, Andino, R. | | 登録日 | 2022-08-16 | | 公開日 | 2023-08-30 | | 最終更新日 | 2023-12-06 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | A tradeoff between enterovirus A71 particle stability and cell entry.
Nat Commun, 14, 2023
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8E3A
 | | Purification of Enterovirus A71, strain 4643, WT capsid | | 分子名称: | VP1, VP2, VP3, ... | | 著者 | Catching, A, Capponi, S, Andino, R. | | 登録日 | 2022-08-16 | | 公開日 | 2023-08-30 | | 最終更新日 | 2023-12-06 | | 実験手法 | ELECTRON MICROSCOPY (7.4 Å) | | 主引用文献 | A tradeoff between enterovirus A71 particle stability and cell entry.
Nat Commun, 14, 2023
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6PNR
 | | A GH31 family sulfoquinovosidase from E. rectale in complex with aza-sugar inhibitor IFGSQ | | 分子名称: | Alpha-glucosidase, SULFATE ION, [(3~{S},4~{R},5~{R})-4,5-bis(oxidanyl)piperidin-3-yl]methanesulfonic acid | | 著者 | Jarva, M.A, Lingford, J.P, John, A, Goddard-Borger, E.D. | | 登録日 | 2019-07-03 | | 公開日 | 2020-07-08 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A GH31 family sulfoquinovosidase from E. rectale in complex with aza-sugar inhibitor IFGSQ
To Be Published
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5NE4
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1M3S
 | | Crystal structure of YckF from Bacillus subtilis | | 分子名称: | Hypothetical protein yckf | | 著者 | Sanishvili, R, Wu, R, Kim, D.E, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2002-06-28 | | 公開日 | 2003-01-21 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal structure of Bacillus subtilis YckF: structural and functional evolution.
J.Struct.Biol., 148, 2004
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8E1E
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6XVK
 | | Crystal structure of the KDR (VEGFR2) kinase domain in complex with a type-II inhibitor bearing an acrylamide | | 分子名称: | Vascular endothelial growth factor receptor 2, ~{N}-(4,4-dimethyl-2-prop-1-ynyl-3,1-benzoxazin-6-yl)-2-[3-methoxy-5-(7-methoxyquinolin-4-yl)oxy-pyridin-2-yl]ethanamide | | 著者 | Schimpl, M, McAuley, K, Hoyt, E.A, Thomas, M, Bodnarchuk, M.S, Lewis, H.J, Barratt, D, Deery, M.J, Ogg, D.J, Bernardes, G.J.L, Ward, R.A, Kettle, J.G, Waring, M.J. | | 登録日 | 2020-01-22 | | 公開日 | 2020-05-27 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Alkynyl Benzoxazines and Dihydroquinazolines as Cysteine Targeting Covalent Warheads and Their Application in Identification of Selective Irreversible Kinase Inhibitors.
J.Am.Chem.Soc., 142, 2020
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6XVX
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5MZG
 | | Crystal structure of mouse MTH1 in complex with TH588 | | 分子名称: | 7,8-dihydro-8-oxoguanine triphosphatase, N~4~-cyclopropyl-6-(2,3-dichlorophenyl)pyrimidine-2,4-diamine, SULFATE ION, ... | | 著者 | Narwal, M, Jemth, A.-S, Helleday, T, Stenmark, P. | | 登録日 | 2017-01-31 | | 公開日 | 2018-01-10 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystal Structures and Inhibitor Interactions of Mouse and Dog MTH1 Reveal Species-Specific Differences in Affinity.
Biochemistry, 57, 2018
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6PPX
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8E2Y
 | | Purification of Enterovirus A71, strain 4643, WT capsid | | 分子名称: | Genome polyprotein, VP1, VP2 | | 著者 | Catching, A, Capponi, S, Andino, R. | | 登録日 | 2022-08-16 | | 公開日 | 2023-08-30 | | 最終更新日 | 2023-12-06 | | 実験手法 | ELECTRON MICROSCOPY (8 Å) | | 主引用文献 | A tradeoff between enterovirus A71 particle stability and cell entry.
Nat Commun, 14, 2023
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8QRJ
 | | LCC-ICCG PETase mutant H218Y | | 分子名称: | 1,2-ETHANEDIOL, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, CALCIUM ION, ... | | 著者 | Orr, G, Niv, Y, Barakat, M, Boginya, A, Dessau, M, Afriat-Jurnou, L. | | 登録日 | 2023-10-09 | | 公開日 | 2024-09-18 | | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | | 主引用文献 | Streamlined screening of extracellularly expressed PETase libraries for improved polyethylene terephthalate degradation.
Biotechnol J, 19, 2024
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6R7I
 | | Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome | | 分子名称: | COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ... | | 著者 | Faull, S.F, Lau, A.M.C, Beuron, F, Cronin, N.B, Morris, E.P, Politis, A. | | 登録日 | 2019-03-28 | | 公開日 | 2019-08-28 | | 最終更新日 | 2024-11-13 | | 実験手法 | ELECTRON MICROSCOPY (5.9 Å) | | 主引用文献 | Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome.
Nat Commun, 10, 2019
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4YSM
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7M6R
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6R67
 | | Crystal structure of transthyretin in complex with CHF5075, a flurbiprofen analogue | | 分子名称: | (2~{R})-2-[4-(3,5-dimethylphenyl)-3-fluoranyl-phenyl]propanoic acid, Transthyretin | | 著者 | Loconte, V, Menozzi, I, Ferrari, A, Berni, R, Zanotti, G. | | 登録日 | 2019-03-26 | | 公開日 | 2019-09-11 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin.
J.Struct.Biol., 208, 2019
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7M6S
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7M6O
 | | Full length alpha1 Glycine receptor in presence of 0.1mM Glycine and 32uM Tetrahydrocannabinol | | 分子名称: | (6aR,10aR)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCINE, ... | | 著者 | Kumar, A, Chakrapani, S. | | 登録日 | 2021-03-26 | | 公開日 | 2022-08-03 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | | 主引用文献 | Structural basis for cannabinoid-induced potentiation of alpha1-glycine receptors in lipid nanodiscs.
Nat Commun, 13, 2022
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7S8C
 | | Cryo-EM structure of human TRPV6 in complex with inhibitor econazole | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 1-[(2R)-2-[(4-chlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole, CALCIUM ION, ... | | 著者 | Neuberger, A, Nadezhdin, K.D, Sobolevsky, A.I. | | 登録日 | 2021-09-17 | | 公開日 | 2021-11-17 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | | 主引用文献 | Structural mechanisms of TRPV6 inhibition by ruthenium red and econazole.
Nat Commun, 12, 2021
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8UPH
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