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PDB: 88675 件

6Q62
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Xanthomonas albilineans Dihydropteroate synthase in complex with (indole-2-carboxylic acid) and (6-chloroguanine)
分子名称: 1,2-ETHANEDIOL, 1H-indole-2-carboxylic acid, 6-chloroguanine, ...
著者Oliveira, A.A, Hyvonen, M, Guido, R.V.C.
登録日2018-12-10
公開日2020-01-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Xanthomonas albilineans Dihydropteroate synthase in complex with (indole-2-carboxylic acid) and (6-chloroguanine)
To Be Published
6YQ5
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Hybrid structure of the SPP1 tail tube by solid-state NMR and cryo EM - NMR Ensemble
分子名称: Tail tube protein gp17.1*
著者Zinke, M, Sachowsky, K.A.A, Zinn-Justin, S, Ravelli, R, Schroder, G.F, Habeck, M, Lange, A.
登録日2020-04-16
公開日2020-10-14
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (4 Å), SOLID-STATE NMR
主引用文献Architecture of the flexible tail tube of bacteriophage SPP1.
Nat Commun, 11, 2020
6NK7
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Electron Cryo-Microscopy of Chikungunya in Complex with Mouse Mxra8 Receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, E1 glycoprotein, ...
著者Basore, K, Kim, A.S, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2019-01-04
公開日2019-05-22
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.99 Å)
主引用文献Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor.
Cell, 177, 2019
7BFY
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Structure of the apo form of the N terminal domain of Bc2L-C lectin (1-131)
分子名称: Lectin
著者Lal, K, Bermeo, R, Imberty, A, Varrot, A.
登録日2021-01-05
公開日2021-04-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Prediction and Validation of a Druggable Site on Virulence Factor of Drug Resistant Burkholderia cenocepacia*.
Chemistry, 27, 2021
7SVQ
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Crystal Structure of L-galactose dehydrogenase from Spinacia oleracea in complex with NAD+
分子名称: L-galactose dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Santillan, J.A.V, Cabrejos, D.A.L, Pereira, H.M, Gomez, J.C.C, Garratt, R.C.
登録日2021-11-19
公開日2022-07-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural Characterization of L-Galactose Dehydrogenase: An Essential Enzyme for Vitamin C Biosynthesis.
Plant Cell.Physiol., 63, 2022
6Y0G
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Structure of human ribosome in classical-PRE state
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ...
著者Bhaskar, V, Schenk, A.D, Cavadini, S, von Loeffelholz, O, Natchiar, S.K, Klaholz, B.P, Chao, J.A.
登録日2020-02-07
公開日2020-04-15
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes.
Cell Rep, 31, 2020
6YZ0
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Full length Open-form Sodium Channel NavMs F208L in complex with Cannabidiol (CBD)
分子名称: 2-[(1R,2R,5S)-5-methyl-2-(prop-1-en-2-yl)cyclohexyl]-5-pentylbenzene-1,3-diol, DODECAETHYLENE GLYCOL, HEGA-10, ...
著者Sula, A, Sait, L.G, Hollingworth, D, Wallace, B.A.
登録日2020-05-06
公開日2020-11-11
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Cannabidiol interactions with voltage-gated sodium channels.
Elife, 9, 2020
7BIV
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Inhibitor of MDM2-p53 Interaction
分子名称: 1,2-ETHANEDIOL, 6-[[(1~{R})-1-(4-chlorophenyl)-7-fluoranyl-1-[[1-(hydroxymethyl)cyclopropyl]methoxy]-3-oxidanylidene-5-(2-oxidanylpropan-2-yl)isoindol-2-yl]methyl]pyridine-3-carbonitrile, DIMETHYL SULFOXIDE, ...
著者Williams, P.A.
登録日2021-01-13
公開日2021-04-07
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Structure-Based Design of Potent and Orally Active Isoindolinone Inhibitors of MDM2-p53 Protein-Protein Interaction.
J.Med.Chem., 64, 2021
5NFF
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Crystal structure of GP1 receptor binding domain from Morogoro virus
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, ...
著者Israeli, H, Cohen-Dvashi, H, Shulman, A, Shimon, A, Diskin, R.
登録日2017-03-14
公開日2017-04-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.615 Å)
主引用文献Mapping of the Lassa virus LAMP1 binding site reveals unique determinants not shared by other old world arenaviruses.
PLoS Pathog., 13, 2017
6PY9
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Crystal structure of red kidney bean purple acid phosphatase in complex with adenosine diphosphate metavanadate
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADP METAVANADATE, ...
著者Feder, D, Schenk, G, Guddat, L.W, McGeary, R.P, Mitic, N, Furtado, A, Schulz, B.L, Henry, R.J, Schmidt, S.
登録日2019-07-29
公開日2020-04-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural elements that modulate the substrate specificity of plant purple acid phosphatases: Avenues for improved phosphorus acquisition in crops.
Plant Sci., 294, 2020
6Z2J
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The structure of the dimeric HDAC1/MIDEAS/DNTTIP1 MiDAC deacetylase complex
分子名称: Deoxynucleotidyltransferase terminal-interacting protein 1, Histone deacetylase 1, INOSITOL HEXAKISPHOSPHATE, ...
著者Fairall, L, Saleh, A, Ragan, T.J, Millard, C.J, Savva, C.G, Schwabe, J.W.R.
登録日2020-05-16
公開日2020-07-08
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献The MiDAC histone deacetylase complex is essential for embryonic development and has a unique multivalent structure.
Nat Commun, 11, 2020
7ZP8
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70S E. coli ribosome with a stalled filamin domain 5 nascent chain
分子名称: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
著者Mitropoulou, A, Plessa, E, Wlodarski, T, Ahn, M, Chan, S.H.S, Becker, T.A, Beckmann, R, Cabrita, L.D, Christodoulou, J.
登録日2022-04-26
公開日2022-08-10
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Modulating co-translational protein folding by rational design and ribosome engineering.
Nat Commun, 13, 2022
7ZQ6
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70S E. coli ribosome with truncated uL23 and uL24 loops and a stalled filamin domain 5 nascent chain
分子名称: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
著者Mitropoulou, A, Wlodarski, T, Ahn, M, Becker, T.A, Beckmann, R, Cabrita, L.D, Christodoulou, J.
登録日2022-04-29
公開日2022-08-10
実験手法ELECTRON MICROSCOPY (2.75 Å)
主引用文献Modulating co-translational protein folding by rational design and ribosome engineering.
Nat Commun, 13, 2022
6Z45
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CDK9-Cyclin-T1 complex bound by compound 24
分子名称: (1~{S},3~{R})-3-acetamido-~{N}-[5-chloranyl-4-(5,5-dimethyl-4,6-dihydropyrrolo[1,2-b]pyrazol-3-yl)pyridin-2-yl]cyclohexane-1-carboxamide, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cyclin-T1, ...
著者Ferguson, A, Collie, G.W.
登録日2020-05-22
公開日2020-12-23
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (3.37 Å)
主引用文献Discovery of AZD4573, a Potent and Selective Inhibitor of CDK9 That Enables Short Duration of Target Engagement for the Treatment of Hematological Malignancies.
J.Med.Chem., 63, 2020
8VFV
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HIV Env BG505_MD39_B16 SOSIP boosting trimer in complex with B16_d77.5 mouse Fab and RM20A3 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, B16_d77.5 mouse Fab heavy chain Fv, ...
著者Ozorowski, G, Torres, J.L, Ward, A.B.
登録日2023-12-22
公開日2024-05-15
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献mRNA-LNP HIV-1 trimer boosters elicit precursors to broad neutralizing antibodies.
Science, 384, 2024
8FBX
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Selenosugar synthase SenB from Variovorax paradoxus
分子名称: CHLORIDE ION, SODIUM ION, Selenosugar synthase SenB
著者Ireland, K.A, Davis, K.M.
登録日2022-11-30
公開日2023-11-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural Characterization and Ligand-Induced Conformational Changes of SenB, a Se-Glycosyltransferase Involved in Selenoneine Biosynthesis.
Biochemistry, 62, 2023
7ZOD
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70S E. coli ribosome with an extended uL23 loop from Candidatus marinimicrobia
分子名称: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
著者Mitropoulou, A, Plessa, E, Wlodarski, T, Ahn, M, Sidhu, H, Becker, T.A, Beckmann, R, Cabrita, L.D, Christodoulou, J.
登録日2022-04-25
公開日2022-08-10
実験手法ELECTRON MICROSCOPY (2.56 Å)
主引用文献Modulating co-translational protein folding by rational design and ribosome engineering.
Nat Commun, 13, 2022
7BVI
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Crystal structure of Pennisetum glaucum monodehydroascorbate reductase
分子名称: ACETATE ION, FLAVIN-ADENINE DINUCLEOTIDE, Pennisetum glaucum monodehydroascorbate reductase
著者Sonkar, K.S, Arulandu, A, Achary, M.M, Reddy, M.K.
登録日2020-04-10
公開日2021-04-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.391 Å)
主引用文献Biochemical and structural characterization of a robust and thermostable ascorbate recycling monodehydroascorbate reductase (MDHAR) from stress adapted pearl millet.
Biochem.Biophys.Res.Commun., 662, 2023
6VZT
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TTLL6 bound to ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
著者Mahalingan, K.K, Keenen, E.K, Strickland, M, Li, Y, Liu, Y, Ball, H.L, Tanner, M.E, Tjandra, N, Roll-Mecak, A.
登録日2020-02-28
公開日2020-08-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Structural basis for polyglutamate chain initiation and elongation by TTLL family enzymes.
Nat.Struct.Mol.Biol., 27, 2020
6Z5S
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RC-LH1(14)-W complex from Rhodopseudomonas palustris
分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, (6~{R},10~{S},14~{R},19~{R},23~{S},24~{E},27~{S},28~{E})-2,6,10,14,19,23,27,31-octamethyldotriaconta-24,28-dien-2-ol, ...
著者Swainsbury, D.J.K, Qian, P, Hitchcock, A, Hunter, C.N.
登録日2020-05-27
公開日2021-01-13
最終更新日2021-02-10
実験手法ELECTRON MICROSCOPY (2.65 Å)
主引用文献Structures of Rhodopseudomonas palustris RC-LH1 complexes with open or closed quinone channels.
Sci Adv, 7, 2021
6YTF
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Acinetobacter baumannii ribosome-tigecycline complex - 30S subunit head
分子名称: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S13, ...
著者Nicholson, D, Edwards, T.A, O'Neill, A.J, Ranson, N.A.
登録日2020-04-24
公開日2020-09-16
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure of the 70S Ribosome from the Human Pathogen Acinetobacter baumannii in Complex with Clinically Relevant Antibiotics.
Structure, 28, 2020
5KDV
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IMPa metallopeptidase from Pseudomonas aeruginosa
分子名称: 1,2-ETHANEDIOL, Metallopeptidase, SULFATE ION, ...
著者Noach, I, Boraston, A.B.
登録日2016-06-08
公開日2017-01-11
最終更新日2017-02-08
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Recognition of protein-linked glycans as a determinant of peptidase activity.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
8FIG
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BU of 8fig by Molmil
Room-temperature X-ray structure of SARS-CoV-2 main protease double mutant E290A/R298A in complex with GC373
分子名称: 3C-like proteinase nsp5, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide
著者Kovalevsky, A, Coates, L, Kneller, D.W.
登録日2022-12-16
公開日2023-11-22
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Insights into the mechanism of SARS-CoV-2 main protease autocatalytic maturation from model precursors.
Commun Biol, 6, 2023
8DGX
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Crystal structure of MERS-CoV spike stem helix peptide in complex with Fab of broadly neutralizing antibody CC68.109 isolated from a vaccinated COVID-19 convalescent
分子名称: Antibody CC68.109 Fab heavy chain, Antibody CC68.109 Fab light chain, Spike protein S2'
著者Liu, H, Wilson, I.A.
登録日2022-06-24
公開日2023-01-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease.
Immunity, 56, 2023
8DC1
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Structural and biochemical characterization of L. interrogans Lsa45 reveals a penicillin-binding protein with esterase activity
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, IODIDE ION, ...
著者Santos, J.C, Nascimento, A.L.T.O.
登録日2022-06-15
公開日2023-01-11
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Structural and biochemical characterization of Leptospira interrogans Lsa45 reveals a penicillin-binding protein with esterase activity.
Process Biochem, 125, 2023

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件を2024-07-31に公開中

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