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PDB: 88675 件

6OCT
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BU of 6oct by Molmil
Crystal structure of human KCTD16 T1 domain
分子名称: BTB/POZ domain-containing protein KCTD16
著者Zuo, H, Glaaser, I, Zhao, Y, Kurinov, I, Mosyak, L, Wang, H, Liu, J, Park, J, Frangaj, A, Sturchler, E, Zhou, M, McDonald, P, Geng, Y, Slesinger, P.A, Fan, Q.R.
登録日2019-03-25
公開日2019-04-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for auxiliary subunit KCTD16 regulation of the GABABreceptor.
Proc.Natl.Acad.Sci.USA, 116, 2019
6U55
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Anti-Zaire ebolavirus Nucleoprotein Single Domain Antibody Zaire E (ZE) Complexed with Sudan ebolavirus Nucleoprotein C-terminal Domain 634-738
分子名称: Anti-Zaire ebolavirus Nucleoprotein Single Domain Antibody Zaire E (ZE), Nucleoprotein
著者Taylor, A.B, Sherwood, L.J, Hart, P.J, Hayhurst, A.
登録日2019-08-26
公開日2019-11-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Paratope Duality and Gullying are Among the Atypical Recognition Mechanisms Used by a Trio of Nanobodies to Differentiate Ebolavirus Nucleoproteins.
J.Mol.Biol., 431, 2019
6MF4
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BU of 6mf4 by Molmil
Crystal structure of the polo-box domain of Cdc5 from budding yeast.
分子名称: Cell cycle serine/threonine-protein kinase CDC5/MSD2, ZINC ION
著者Guarne, A, Almawi, A.W.
登録日2018-09-09
公開日2020-02-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Distinct surfaces on Cdc5/PLK Polo-box domain orchestrate combinatorial substrate recognition during cell division.
Sci Rep, 10, 2020
6MFB
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BU of 6mfb by Molmil
Crystal structure of 3-hydroxykynurenine transaminase from Aedes aegypti
分子名称: PYRIDOXAL-5'-PHOSPHATE, Serine--pyruvate aminotransferase
著者Maciel, L.G, Oliveira, A.A, Romao, T.P, Silva Filha, M.H.N.L, dos Anjos, J.V, Soares, T.A, Guido, R.V.C.
登録日2018-09-10
公開日2019-09-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of 3-hydroxykynurenine transaminase from Aedes aegypti
To Be Published
8BW0
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BU of 8bw0 by Molmil
Structure of CEACAM5 A3-B3 domain in Complex with Tusamitamab Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Carcinoembryonic antigen-related cell adhesion molecule 5, ...
著者Kumar, A, Bertrand, T, Rapisarda, C, Rak, A.
登録日2022-12-06
公開日2024-01-24
実験手法ELECTRON MICROSCOPY (3.11 Å)
主引用文献Structural insights into epitope-paratope interactions of monoclonal antibody targeting CEACAM5-expressing tumors
Res Sq, 2023
6XN0
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BU of 6xn0 by Molmil
Crystal structure of GH43_1 enzyme from Xanthomonas citri
分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Morais, M.A.B, Tonoli, C.C.C, Santos, C.R, Murakami, M.T.
登録日2020-07-02
公開日2020-12-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.709 Å)
主引用文献Two distinct catalytic pathways for GH43 xylanolytic enzymes unveiled by X-ray and QM/MM simulations.
Nat Commun, 12, 2021
5LNH
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BU of 5lnh by Molmil
Structure of full length Unliganded CodY from Bacillus subtilis
分子名称: GTP-sensing transcriptional pleiotropic repressor CodY, SULFATE ION
著者Wilkinson, A.J, Levdikov, V.M, Blagova, E.V.
登録日2016-08-04
公開日2017-01-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of the Branched-chain Amino Acid and GTP-sensing Global Regulator, CodY, from Bacillus subtilis.
J. Biol. Chem., 292, 2017
8E2X
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Purification of Enterovirus A71, strain 4643, WT capsid
分子名称: SPHINGOSINE, VP1, VP2, ...
著者Catching, A, Capponi, S, Andino, R.
登録日2022-08-16
公開日2023-08-30
最終更新日2023-12-06
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献A tradeoff between enterovirus A71 particle stability and cell entry.
Nat Commun, 14, 2023
8E3C
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Purification of Enterovirus A71, strain 4643, WT capsid
分子名称: VP1, VP2, VP3
著者Catching, A, Capponi, S, Andino, R.
登録日2022-08-16
公開日2023-08-30
最終更新日2023-12-06
実験手法ELECTRON MICROSCOPY (7.1 Å)
主引用文献A tradeoff between enterovirus A71 particle stability and cell entry.
Nat Commun, 14, 2023
6OG1
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Focus classification structure of the hyperactive ClpB mutant K476C, bound to casein, pre-state
分子名称: ADENOSINE-5'-DIPHOSPHATE, Hyperactive disaggregase ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
著者Rizo, A.R, Lin, J.-B, Gates, S.N, Tse, E, Bart, S.M, Castellano, L.M, Dimaio, F, Shorter, J, Southworth, D.R.
登録日2019-04-01
公開日2019-06-12
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis for substrate gripping and translocation by the ClpB AAA+ disaggregase.
Nat Commun, 10, 2019
6UIU
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BU of 6uiu by Molmil
Artificial Iron Proteins: Modelling the Active Sites in Non-Heme Dioxygenases
分子名称: N-(2-{bis[(pyridin-2-yl)methyl]amino}ethyl)-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide, Streptavidin
著者Miller, K.R, Paretsky, J.D, Follmer, A.H, Heinisch, T, Mittra, K, Gul, S, Kim, I.-S, Fuller, F.D, Batyuk, A, Sutherlin, K.D, Brewster, A.S, Bhowmick, A, Sauter, N.K, Kern, J, Yano, J, Green, M.T, Ward, T.R, Borovik, A.S.
登録日2019-10-01
公開日2020-05-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Artificial Iron Proteins: Modeling the Active Sites in Non-Heme Dioxygenases.
Inorg.Chem., 59, 2020
7S8H
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BU of 7s8h by Molmil
Structure of Lassa virus glycoprotein bound to Fab 18.5C and Fab 36.1F
分子名称: 18.5C Fab Heavy Chain, 18.5C Fab Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Hastie, K.M, Enriquez, A.S.
登録日2021-09-17
公開日2022-06-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Delineating the mechanism of anti-Lassa virus GPC-A neutralizing antibodies.
Cell Rep, 39, 2022
8GM7
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BU of 8gm7 by Molmil
Structure of apurinic/apyrimidinic DNA Lyase TK0353 from Thermococcus kodakarensis (Native Crystal Form)
分子名称: GLYCEROL, SULFATE ION, TK0353
著者Eckenroth, B.E, Gardner, A.F, Doublie, S.
登録日2023-03-24
公開日2023-12-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Thermococcus kodakarensis TK0353 is a novel AP lyase with a new fold.
J.Biol.Chem., 300, 2023
7N7Z
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BU of 7n7z by Molmil
Structure of Acetyl-CoA acetyltransferase from Syntrophomonas wolfei
分子名称: Acetyl-CoA C-acetyltransferase
著者Arbing, M.A, Gunsalus, R.P.
登録日2021-06-11
公開日2021-06-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Dynamic acylome reveals metabolite driven modifications in Syntrophomonas wolfei.
Front Microbiol, 13, 2022
5IGY
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BU of 5igy by Molmil
Macrolide 2'-phosphotransferase type II - complex with GDP and erythromycin
分子名称: CALCIUM ION, ERYTHROMYCIN A, GUANOSINE-5'-DIPHOSPHATE, ...
著者Berghuis, A.M, Fong, D.H.
登録日2016-02-28
公開日2017-04-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance.
Structure, 25, 2017
8E1E
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BU of 8e1e by Molmil
Scaffolding protein functional sites using deep learning
分子名称: SG122_C3
著者Bera, A.K, Gerben, S, Baker, D.
登録日2022-08-10
公開日2023-08-16
実験手法X-RAY DIFFRACTION (4.27 Å)
主引用文献Design of Diverse Asymmetric Pockets in De Novo Homo-oligomeric Proteins.
Biochemistry, 62, 2023
6UKJ
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BU of 6ukj by Molmil
Single-Particle Cryo-EM Structure of Plasmodium falciparum Chloroquine Resistance Transporter (PfCRT) 7G8 Isoform
分子名称: CHOLESTEROL HEMISUCCINATE, Chloroquine resistance transporter, Fab Heavy Chain, ...
著者Kim, J, Tan, Y.Z, Wicht, K.J, Erramilli, S.K, Dhingra, S.K, Okombo, J, Vendome, J, Hagenah, L.M, Giacometti, S.I, Warren, A.L, Nosol, K, Roepe, P.D, Potter, C.S, Carragher, B, Kossiakoff, A.A, Quick, M, Fidock, D.A, Mancia, F.
登録日2019-10-05
公開日2019-12-04
最終更新日2020-01-08
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure and drug resistance of the Plasmodium falciparum transporter PfCRT.
Nature, 576, 2019
8E38
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Purification of Enterovirus A71, strain 4643, WT capsid
分子名称: SPHINGOSINE, VP1, VP2, ...
著者Catching, A, Capponi, S, Andino, R.
登録日2022-08-16
公開日2023-08-30
最終更新日2023-12-06
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献A tradeoff between enterovirus A71 particle stability and cell entry.
Nat Commun, 14, 2023
6XCC
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BU of 6xcc by Molmil
Structure of the C. botulinum neurotoxin serotype A light chain protease in complex with covalent inhibitor 21
分子名称: Botulinum neurotoxin type A, N-hydroxy-5-sulfanylpentanamide, ZINC ION
著者Tararina, M.A, Allen, K.N.
登録日2020-06-08
公開日2020-09-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Catch and Anchor Approach To Combat Both Toxicity and Longevity of Botulinum Toxin A.
J.Med.Chem., 63, 2020
8T6I
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BU of 8t6i by Molmil
Structure of VHH-Fab complex with engineered Crystal Kappa region
分子名称: Fab heavy chain, Fab light chain, GLYCEROL, ...
著者Filippova, E.V, Thompson, I, Kossiakoff, A.A.
登録日2023-06-16
公開日2023-11-29
最終更新日2024-01-03
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes.
Protein Sci., 33, 2024
8E2Y
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BU of 8e2y by Molmil
Purification of Enterovirus A71, strain 4643, WT capsid
分子名称: Genome polyprotein, VP1, VP2
著者Catching, A, Capponi, S, Andino, R.
登録日2022-08-16
公開日2023-08-30
最終更新日2023-12-06
実験手法ELECTRON MICROSCOPY (8 Å)
主引用文献A tradeoff between enterovirus A71 particle stability and cell entry.
Nat Commun, 14, 2023
8E3A
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BU of 8e3a by Molmil
Purification of Enterovirus A71, strain 4643, WT capsid
分子名称: VP1, VP2, VP3, ...
著者Catching, A, Capponi, S, Andino, R.
登録日2022-08-16
公開日2023-08-30
最終更新日2023-12-06
実験手法ELECTRON MICROSCOPY (7.4 Å)
主引用文献A tradeoff between enterovirus A71 particle stability and cell entry.
Nat Commun, 14, 2023
6MG8
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BU of 6mg8 by Molmil
Structural basis for cholesterol transport-like activity of the Hedgehog receptor Patched
分子名称: CHOLESTEROL, Protein patched homolog 1
著者Zhang, Y, Bulkley, D, Xin, Y, Roberts, K.J, Asarnow, D.E, Sharma, A, Myers, B.R, Cho, W, Cheng, Y, Beachy, P.A.
登録日2018-09-13
公開日2018-11-28
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural Basis for Cholesterol Transport-like Activity of the Hedgehog Receptor Patched.
Cell, 175, 2018
6U52
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Anti-Sudan ebolavirus Nucleoprotein Single Domain Antibody Sudan B (SB) Complexed with Sudan ebolavirus Nucleoprotein C-terminal Domain 634-738
分子名称: Anti-Sudan ebolavirus Nucleoprotein Single Domain Antibody Sudan B (SB), CHLORIDE ION, Nucleoprotein
著者Taylor, A.B, Sherwood, L.J, Hart, P.J, Hayhurst, A.
登録日2019-08-26
公開日2019-11-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Paratope Duality and Gullying are Among the Atypical Recognition Mechanisms Used by a Trio of Nanobodies to Differentiate Ebolavirus Nucleoproteins.
J.Mol.Biol., 431, 2019
6MEN
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BU of 6men by Molmil
Crystal structure of a Tylonycteris bat coronavirus HKU4 macrodomain in complex with adenosine diphosphate glucose (ADP-glucose)
分子名称: ADENOSINE-5'-DIPHOSPHATE-GLUCOSE, Replicase polyprotein 1ab
著者Hammond, R.G, Schormann, N, McPherson, R.L, Leung, A.K.L, Deivanayagam, C.C.S, Johnson, M.A.
登録日2018-09-06
公開日2019-09-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献ADP-Ribose and Analogues bound to the DeMARylating Macrodomain from the Bat Coronavirus HKU4
Proc.Natl.Acad.Sci.USA, 2021

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件を2024-07-31に公開中

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