4RH0
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![BU of 4rh0 by Molmil](/molmil-images/mine/4rh0) | Spore photoproduct lyase C140A/S76C mutant with bound AdoMet | 分子名称: | 1,2-ETHANEDIOL, IRON/SULFUR CLUSTER, SULFATE ION, ... | 著者 | Benjdia, A, Heil, K, Winkler, A, Carell, T, Schlichting, I. | 登録日 | 2014-10-01 | 公開日 | 2014-10-22 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Rescuing DNA repair activity by rewiring the H-atom transfer pathway in the radical SAM enzyme, spore photoproduct lyase. Chem.Commun.(Camb.), 50, 2014
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4RH1
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![BU of 4rh1 by Molmil](/molmil-images/mine/4rh1) | Spore photoproduct lyase C140A/S76C mutant with bound AdoMet and dinucleoside spore photoproduct | 分子名称: | 1-[(2R,4S,5R)-5-(hydroxymethyl)-4-oxidanyl-oxolan-2-yl]-5-[[(5R)-1-[(2R,4S,5R)-5-(hydroxymethyl)-4-oxidanyl-oxolan-2-yl]-5-methyl-2,4-bis(oxidanylidene)-1,3-diazinan-5-yl]methyl]pyrimidine-2,4-dione, IRON/SULFUR CLUSTER, SULFATE ION, ... | 著者 | Benjdia, A, Heil, K, Winkler, A, Carell, T, Schlichting, I. | 登録日 | 2014-10-01 | 公開日 | 2014-10-22 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Rescuing DNA repair activity by rewiring the H-atom transfer pathway in the radical SAM enzyme, spore photoproduct lyase. Chem.Commun.(Camb.), 50, 2014
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6PZ1
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![BU of 6pz1 by Molmil](/molmil-images/mine/6pz1) | Crystal Structure of human Indoleamine 2,3-Dioxygenase 1 in complex with PF-06840003 in Active Site and Si site | 分子名称: | (3R)-3-(5-fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione, GLYCEROL, Indoleamine 2,3-dioxygenase 1, ... | 著者 | Pham, K.N, Lewis-Ballester, A, Yeh, S.R. | 登録日 | 2019-07-31 | 公開日 | 2020-01-01 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Structural Basis of Inhibitor Selectivity in Human Indoleamine 2,3-Dioxygenase 1 and Tryptophan Dioxygenase. J.Am.Chem.Soc., 141, 2019
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4RD8
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![BU of 4rd8 by Molmil](/molmil-images/mine/4rd8) | The crystal structure of a functionally-unknown protein from Legionella pneumophila subsp. pneumophila str. Philadelphia 1 | 分子名称: | Uncharacterized protein | 著者 | Tan, K, Xu, X, Cui, H, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2014-09-18 | 公開日 | 2014-10-01 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | The crystal structure of a functionally-unknown protein from Legionella pneumophila subsp. pneumophila str. Philadelphia 1 To be Published
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7AFR
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![BU of 7afr by Molmil](/molmil-images/mine/7afr) | Ribosome maturation factor RimP (apo) | 分子名称: | Ribosome maturation factor RimP | 著者 | Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Fucini, P, Connell, S. | 登録日 | 2020-09-19 | 公開日 | 2021-07-07 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit. Sci Adv, 7, 2021
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1T8U
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![BU of 1t8u by Molmil](/molmil-images/mine/1t8u) | Crystal Structure of human 3-O-Sulfotransferase-3 with bound PAP and tetrasaccharide substrate | 分子名称: | 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, ADENOSINE-3'-5'-DIPHOSPHATE, SODIUM ION, ... | 著者 | Moon, A.F, Edavettal, S.C, Krahn, J.M, Munoz, E.M, Negishi, M, Linhardt, R.J, Liu, J, Pedersen, L.C. | 登録日 | 2004-05-13 | 公開日 | 2004-08-31 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural analysis of the sulfotransferase (3-o-sulfotransferase isoform 3) involved in the biosynthesis of an entry receptor for herpes simplex virus 1 J.Biol.Chem., 279, 2004
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7T8V
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![BU of 7t8v by Molmil](/molmil-images/mine/7t8v) | Co-crystal structure of Chaetomium glucosidase I with EB-0159 | 分子名称: | (1S,2S,3R,4S,5S)-1-(hydroxymethyl)-5-[(6-{[2-nitro-4-(1H-1,2,3-triazol-1-yl)phenyl]amino}hexyl)amino]cyclohexane-1,2,3,4-tetrol, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Karade, S.S, Mariuzza, R.A. | 登録日 | 2021-12-17 | 公開日 | 2022-05-04 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Identification of Endoplasmic Reticulum alpha-Glucosidase I from a Thermophilic Fungus as a Platform for Structure-Guided Antiviral Drug Design. Biochemistry, 61, 2022
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7B9E
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![BU of 7b9e by Molmil](/molmil-images/mine/7b9e) | Crystal structure of MurE from E.coli in complex with Z275151340 | 分子名称: | 4-chloro-N-cyclopentyl-1-methyl-1H-pyrazole-3-carboxamide, ISOPROPYL ALCOHOL, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-2,6-diaminopimelate ligase | 著者 | Koekemoer, L, Steindel, M, Fairhead, M, Talon, R, Douangamath, A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, von Delft, F, Krojer, T, Structural Genomics Consortium (SGC) | 登録日 | 2020-12-14 | 公開日 | 2020-12-23 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Crystal structure of MurE from E.coli To Be Published
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5KOK
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![BU of 5kok by Molmil](/molmil-images/mine/5kok) | Pavine N-methyltransferase in complex with Tetrahydropapaverine and S-adenosylhomocysteine pH 7.25 | 分子名称: | (1~{R})-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline, (1~{S})-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline, Pavine N-methyltransferase, ... | 著者 | Torres, M.A, Hoffarth, E, Eugenio, L, Savtchouk, J, Chen, X, Morris, J, Facchini, P.J, Ng, K.K.S. | 登録日 | 2016-06-30 | 公開日 | 2016-09-07 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.792 Å) | 主引用文献 | Structural and Functional Studies of Pavine N-Methyltransferase from Thalictrum flavum Reveal Novel Insights into Substrate Recognition and Catalytic Mechanism. J.Biol.Chem., 291, 2016
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7ZYG
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![BU of 7zyg by Molmil](/molmil-images/mine/7zyg) | CryoEM structure of Ku heterodimer bound to DNA, PAXX and XLF | 分子名称: | DNA, Non-homologous end-joining factor 1, PHOSPHATE ION, ... | 著者 | Hardwick, S.W, Kefala-Stavridi, A, Chirgadze, D.Y, Blundell, T.L, Chaplin, A.K. | 登録日 | 2022-05-24 | 公開日 | 2023-06-07 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.68 Å) | 主引用文献 | PAXX binding to the NHEJ machinery explains functional redundancy with XLF. Sci Adv, 9, 2023
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7T66
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![BU of 7t66 by Molmil](/molmil-images/mine/7t66) | Co-crystal structure of Chaetomium glucosidase with compound UV-4 | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Chaetomium alpha glucosidase, ... | 著者 | Karade, S.S, Mariuzza, R.A. | 登録日 | 2021-12-13 | 公開日 | 2022-05-04 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Identification of Endoplasmic Reticulum alpha-Glucosidase I from a Thermophilic Fungus as a Platform for Structure-Guided Antiviral Drug Design. Biochemistry, 61, 2022
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6W9P
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![BU of 6w9p by Molmil](/molmil-images/mine/6w9p) | Tel26 Parallel Four-quartet G-quadruplex with K+ | 分子名称: | DNA (5'-D(P*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*T)-3'), POTASSIUM ION, SODIUM ION | 著者 | McCarthy, S.E, Yatsunyk, L.A, Beseiso, D, Miao, J. | 登録日 | 2020-03-23 | 公開日 | 2021-03-31 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | The first crystal structures of hybrid and parallel four-tetrad intramolecular G-quadruplexes. Nucleic Acids Res., 50, 2022
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7T68
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![BU of 7t68 by Molmil](/molmil-images/mine/7t68) | Co-crystal structure of Chaetomium glucosidase with compound UV-5 | 分子名称: | (2R,3R,4R,5S)-1-[6-(4-azido-2-nitroanilino)hexyl]-2-(hydroxymethyl)piperidine-3,4,5-triol, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Karade, S.S, Mariuzza, R.A. | 登録日 | 2021-12-13 | 公開日 | 2022-05-04 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | Identification of Endoplasmic Reticulum alpha-Glucosidase I from a Thermophilic Fungus as a Platform for Structure-Guided Antiviral Drug Design. Biochemistry, 61, 2022
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8A1N
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![BU of 8a1n by Molmil](/molmil-images/mine/8a1n) | Crystal structure of the transpeptidase LdtMt2 from Mycobacterium tuberculosis in complex with fumaryl amide analogue 13 | 分子名称: | (Z)-N-(4-chlorophenyl)-4-oxidanylidene-but-2-enamide, 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, ... | 著者 | de Munnik, M, Lang, P.A, Brem, J, Schofield, C.J. | 登録日 | 2022-06-01 | 公開日 | 2023-06-14 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | High-throughput screen with the l,d-transpeptidase Ldt Mt2 of Mycobacterium tuberculosis reveals novel classes of covalently reacting inhibitors. Chem Sci, 14, 2023
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7T6W
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![BU of 7t6w by Molmil](/molmil-images/mine/7t6w) | Crystal structure of Chaetomium Glucosidase I (apo) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chaetomium alpha glucosidase, GLYCEROL, ... | 著者 | Karade, S.S, Mariuzza, R.A. | 登録日 | 2021-12-14 | 公開日 | 2022-05-04 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Identification of Endoplasmic Reticulum alpha-Glucosidase I from a Thermophilic Fungus as a Platform for Structure-Guided Antiviral Drug Design. Biochemistry, 61, 2022
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5KLB
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![BU of 5klb by Molmil](/molmil-images/mine/5klb) | Crystal structure of the CavAb voltage-gated calcium channel(wild-type, 2.7A) | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, CALCIUM ION, ... | 著者 | Tang, L, Gamal EL-Din, T.M, Swanson, T.M, Pryde, D.C, Scheuer, T, Zheng, N, Catterall, W.A. | 登録日 | 2016-06-23 | 公開日 | 2016-08-31 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs. Nature, 537, 2016
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3ETI
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![BU of 3eti by Molmil](/molmil-images/mine/3eti) | |
3ESX
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![BU of 3esx by Molmil](/molmil-images/mine/3esx) | E16KE61KD126KD150K Flavodoxin from Anabaena | 分子名称: | CALCIUM ION, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ... | 著者 | Herguedas, B, Hermoso, J.A, Martinez-Julvez, M, Goni, G, Medina, M. | 登録日 | 2008-10-06 | 公開日 | 2009-02-10 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Flavodoxin: A compromise between efficiency and versatility in the electron transfer from Photosystem I to Ferredoxin-NADP(+) reductase Biochim.Biophys.Acta, 1787, 2009
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8A29
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![BU of 8a29 by Molmil](/molmil-images/mine/8a29) | Apo 1-deoxy-D-xylulose 5-phosphate synthase from Pseudomonas aeruginosa | 分子名称: | 1-deoxy-D-xylulose-5-phosphate synthase, CALCIUM ION, CHLORIDE ION, ... | 著者 | Hamid, R, Adam, S, Lacour, A, Monjas, L, Hirsch, A. | 登録日 | 2022-06-02 | 公開日 | 2023-06-14 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | 1-deoxy-D-xylulose-5-phosphate synthase from Pseudomonas aeruginosa and Klebsiella pneumoniae reveals conformational changes upon cofactor binding. J.Biol.Chem., 299, 2023
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7BUA
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![BU of 7bua by Molmil](/molmil-images/mine/7bua) | Cryo-EM structure of zika virus complexed with Fab SIgN-3C at pH 8.0 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Genome polyprotein, SIgN-3C Fab heavy chain, ... | 著者 | Zhang, S, Chew, S.V, Lim, X.N, Ng, T.S, Kostyuchenko, V.A, Lok, S.M. | 登録日 | 2020-04-06 | 公開日 | 2020-05-13 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | A Human Antibody Neutralizes Different Flaviviruses by Using Different Mechanisms. Cell Rep, 31, 2020
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6J7R
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![BU of 6j7r by Molmil](/molmil-images/mine/6j7r) | Crystal structure of toxin TglT (unusual type guanylyltransferase-like toxin, Rv1045) mutant S78A co-expressed with TakA from Mycobacterium tuberculosis | 分子名称: | MAGNESIUM ION, guanylyltransferase-like toxin | 著者 | Yu, X, Gao, X, Zhu, K, Wojdyla, J.A, Wang, M, Cui, S. | 登録日 | 2019-01-18 | 公開日 | 2020-05-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.299 Å) | 主引用文献 | Characterization of a toxin-antitoxin system in Mycobacterium tuberculosis suggests neutralization by phosphorylation as the antitoxicity mechanism. Commun Biol, 3, 2020
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6PYZ
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![BU of 6pyz by Molmil](/molmil-images/mine/6pyz) | Crystal Structure of human Tryptophan 2,3-dioxygenase in complex with PF-06840003 in Active Site | 分子名称: | (3S)-3-(5-fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione, PROTOPORPHYRIN IX CONTAINING FE, Tryptophan 2,3-dioxygenase, ... | 著者 | Pham, K.N, Lewis-Ballester, A, Yeh, S.R. | 登録日 | 2019-07-31 | 公開日 | 2020-01-01 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Structural Basis of Inhibitor Selectivity in Human Indoleamine 2,3-Dioxygenase 1 and Tryptophan Dioxygenase. J.Am.Chem.Soc., 141, 2019
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8A1O
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![BU of 8a1o by Molmil](/molmil-images/mine/8a1o) | Crystal structure of the transpeptidase LdtMt2 from Mycobacterium tuberculosis in complex with acrylamide analogue 8 | 分子名称: | (E)-3-chloranyl-3-[(2-chlorophenyl)methylsulfonyl]-N-(5-methoxypyridin-2-yl)prop-2-enamide, 1,2-ETHANEDIOL, CHLORIDE ION, ... | 著者 | de Munnik, M, Lang, P.A, Brem, J, Schofield, C.J. | 登録日 | 2022-06-01 | 公開日 | 2023-06-14 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | High-throughput screen with the l,d-transpeptidase Ldt Mt2 of Mycobacterium tuberculosis reveals novel classes of covalently reacting inhibitors. Chem Sci, 14, 2023
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1SUI
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![BU of 1sui by Molmil](/molmil-images/mine/1sui) | Alfalfa caffeoyl coenzyme A 3-O-methyltransferase | 分子名称: | CALCIUM ION, Caffeoyl-CoA O-methyltransferase, FERULOYL COENZYME A, ... | 著者 | Ferrer, J.-L, Zubieta, C, Dixon, R.A, Noel, J.P. | 登録日 | 2004-03-26 | 公開日 | 2005-03-15 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal Structures of Alfalfa Caffeoyl Coenzyme A 3-O-Methyltransferase Plant Physiol., 137, 2005
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8A1L
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![BU of 8a1l by Molmil](/molmil-images/mine/8a1l) | Crystal structure of the transpeptidase LdtMt2 from Mycobacterium tuberculosis in complex with alpha-chloro ketone 2 | 分子名称: | (phenylmethyl) N-[(3S,4S)-4-methyl-2-oxidanylidene-hexan-3-yl]carbamate, 1,2-ETHANEDIOL, CHLORIDE ION, ... | 著者 | de Munnik, M, Lang, P.A, Brem, J, Schofield, C.J. | 登録日 | 2022-06-01 | 公開日 | 2023-06-14 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | High-throughput screen with the l,d-transpeptidase Ldt Mt2 of Mycobacterium tuberculosis reveals novel classes of covalently reacting inhibitors. Chem Sci, 14, 2023
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