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PDB: 89111 件

6SNL
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(R)-selective amine transaminase from Exophiala sideris
分子名称: CHLORIDE ION, GLYCEROL, HEXAETHYLENE GLYCOL, ...
著者Telzerow, A, Hakansson, M, Steiner, K.
登録日2019-08-26
公開日2020-12-09
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.129 Å)
主引用文献Expanding the Toolbox of R-Selective Amine Transaminases by Identification and Characterization of New Members.
Chembiochem, 22, 2021
5K19
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Crystal structure of WD repeat-containing protein 20
分子名称: GLYCEROL, SULFATE ION, WD repeat-containing protein 20
著者Li, H, D'Andrea, A.D, Zheng, N.
登録日2016-05-17
公開日2016-07-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.602 Å)
主引用文献Allosteric Activation of Ubiquitin-Specific Proteases by beta-Propeller Proteins UAF1 and WDR20.
Mol.Cell, 63, 2016
5DIY
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Thermobaculum terrenum O-GlcNAc hydrolase mutant - D120N
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hyaluronidase, TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
著者Ostrowski, A, Gundogdu, M, Ferenbach, A.T, Lebedev, A, van Aalten, D.M.F.
登録日2015-09-01
公開日2015-10-28
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Evidence for a Functional O-Linked N-Acetylglucosamine (O-GlcNAc) System in the Thermophilic Bacterium Thermobaculum terrenum.
J.Biol.Chem., 290, 2015
5UNG
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BU of 5ung by Molmil
XFEL structure of human angiotensin II type 2 receptor (Orthorhombic form) in complex with compound 1 (N-benzyl-N-(2-ethyl-4-oxo-3-{[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl] methyl}-3,4-dihydroquinazolin-6-yl)thiophene-2-carboxamide)
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Chimera protein of Type-2 angiotensin II receptor and Soluble cytochrome b562, N-benzyl-N-(2-ethyl-4-oxo-3-{[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-3,4-dihydroquinazolin-6-yl)thiophene-2-carboxamide, ...
著者Zhang, H, Han, G.W, Batyuk, A, Ishchenko, A, White, K.L, Patel, N, Sadybekov, A, Zamlynny, B, Rudd, M.T, Hollenstein, K, Tolstikova, A, White, T.A, Hunter, M.S, Weierstall, U, Liu, W, Babaoglu, K, Moore, E.L, Katz, R.D, Shipman, J.M, Garcia-Calvo, M, Sharma, S, Sheth, P, Soisson, S.M, Stevens, R.C, Katritch, V, Cherezov, V.
登録日2017-01-30
公開日2017-04-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for selectivity and diversity in angiotensin II receptors.
Nature, 544, 2017
8C3Q
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Crystal structure of DYRK1A in complex with rutin
分子名称: Dual specificity tyrosine-phosphorylation-regulated kinase 1A, RUTIN
著者Grygier, P, Pustelny, K, Dubin, G, Czarna, A.
登録日2022-12-28
公開日2024-01-10
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Crystal structure of DYRK1A in complex with rutin
To Be Published
5DII
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Structure of an engineered bacterial microcompartment shell protein binding a [4Fe-4S] cluster
分子名称: IRON/SULFUR CLUSTER, Microcompartments protein
著者Sutter, M, Aussignargues, C, Turmo, A, Kerfeld, C.A.
登録日2015-09-01
公開日2016-02-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.804 Å)
主引用文献Structure and Function of a Bacterial Microcompartment Shell Protein Engineered to Bind a [4Fe-4S] Cluster.
J.Am.Chem.Soc., 138, 2016
9FJW
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BU of 9fjw by Molmil
Solution NMR structure of a peptide encompassing residues 2-36 of the human formin INF2
分子名称: Inverted formin-2
著者Jimenez, M.A, Comas, L, Labat-de-Hoz, L, Correas, I, Alonso, M.A.
登録日2024-05-31
公開日2024-09-11
実験手法SOLUTION NMR
主引用文献Structure and function of the N-terminal extension of the formin INF2.
Cell Mol Life Sci, 79, 2022
6FZA
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Crystal Structure of lipase from Geobacillus stearothermophilus T6 methanol stable variant A187F
分子名称: CALCIUM ION, Lipase, ZINC ION
著者Gihaz, S, Kanteev, M, Pazy, Y, Fishman, A.
登録日2018-03-14
公開日2018-10-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Filling the Void: Introducing Aromatic Interactions into Solvent Tunnels To Enhance Lipase Stability in Methanol.
Appl.Environ.Microbiol., 84, 2018
4RLG
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BU of 4rlg by Molmil
The clear crystal structure of pyridoxal-dependent decarboxylase from sphaerobacter thermophilus dsm 20745
分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, GAMMA-AMINO-BUTANOIC ACID, GLYCEROL, ...
著者Wu, R, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2014-10-16
公開日2014-10-29
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献The clear crystal structure of pyridoxal-dependent decarboxylase from sphaerobacter thermophilus dsm 20745
TO BE PUBLISHED
4TL1
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GCN4-p1 with mutation to 1-Aminocyclohexanecarboxylic acid at residue 10
分子名称: General control protein GCN4, ISOPROPYL ALCOHOL
著者Tavenor, N.A, Silva, K.I, Saxena, S, Horne, W.S.
登録日2014-05-28
公開日2014-08-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Origins of Structural Flexibility in Protein-Based Supramolecular Polymers Revealed by DEER Spectroscopy.
J.Phys.Chem.B, 118, 2014
4RML
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BU of 4rml by Molmil
Crystal structure of the Olfactomedin domain of latrophilin 3 in C2221 crystal form
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Latrophilin-3, MAGNESIUM ION
著者Ranaivoson, F.M, Liu, Q, Martini, F, Bergami, F, Von daake, S, Li, S, Demeler, B, Hendrickson, W.A, Comoletti, D.
登録日2014-10-21
公開日2015-08-19
最終更新日2015-10-07
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献Structural and Mechanistic Insights into the Latrophilin3-FLRT3 Complex that Mediates Glutamatergic Synapse Development.
Structure, 23, 2015
4TL6
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Crystal structure of N-terminal domain of KaiC
分子名称: CHLORIDE ION, Circadian clock protein kinase KaiC, MAGNESIUM ION, ...
著者Abe, J, Hiyama, T.B, Mukaiyama, A, Son, S, Akiyama, S.
登録日2014-05-29
公開日2015-07-01
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.763 Å)
主引用文献Circadian rhythms. Atomic-scale origins of slowness in the cyanobacterial circadian clock.
Science, 349, 2015
5DJI
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BU of 5dji by Molmil
Structure of M. tuberculosis CysQ, a PAP phosphatase with AMP, PO4, and 2Mg bound
分子名称: 3'-phosphoadenosine 5'-phosphate phosphatase, ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, ...
著者Fisher, A.J, Erickson, A.I.
登録日2015-09-02
公開日2015-11-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.659 Å)
主引用文献Crystal Structures of Mycobacterium tuberculosis CysQ, with Substrate and Products Bound.
Biochemistry, 54, 2015
5UQ3
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BU of 5uq3 by Molmil
Crystal structure of human Cdk2-Spy1-P27 ternary complex
分子名称: Cyclin-dependent kinase 2, Cyclin-dependent kinase inhibitor 1B, Speedy protein A
著者McGrath, D.A, Tripathi, S.M, Rubin, S.M.
登録日2017-02-06
公開日2017-07-05
最終更新日2017-08-09
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structural basis of divergent cyclin-dependent kinase activation by Spy1/RINGO proteins.
EMBO J., 36, 2017
2XJ8
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BU of 2xj8 by Molmil
The structure of ferrous cytochrome c peroxidase
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CYTOCHROME C PEROXIDASE, MITOCHONDRIAL, ...
著者Gumiero, A, Raven, E.L, Moody, P.C.E.
登録日2010-07-02
公開日2010-07-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Nature of the ferryl heme in compounds I and II.
J. Biol. Chem., 286, 2011
6G0S
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BU of 6g0s by Molmil
Crystal Structure of the first bromodomain of human BRD4 in complex with an acetylated SIRT7 peptide (K272ac/K275ac)
分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, NAD-dependent protein deacetylase sirtuin-7
著者Filippakopoulos, P, Picaud, S, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C.
登録日2018-03-19
公開日2018-11-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.
Mol. Cell, 73, 2019
7PP1
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Crystal structure of the P2Y12 receptor in complex with the inverse agonist selatogrel.
分子名称: CHOLESTEROL, P2Y purinoceptor 12,Soluble cytochrome b562,P2Y purinoceptor 12, Selatogrel
著者Mac Sweeney, A, Tidten-Luksch, N.
登録日2021-09-13
公開日2022-11-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Inverse agonist efficacy of selatogrel blunts constitutive P2Y12 receptor signaling by inducing the inactive receptor conformation.
Biochem Pharmacol, 206, 2022
5DQF
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BU of 5dqf by Molmil
Horse Serum Albumin (ESA) in complex with Cetirizine
分子名称: (2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid, (2-{4-[(S)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid, CHLORIDE ION, ...
著者Handing, K.B, Shabalin, I.G, Majorek, K.A, Chruszcz, M, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC)
登録日2015-09-14
公開日2015-12-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of equine serum albumin in complex with cetirizine reveals a novel drug binding site.
Mol.Immunol., 71, 2016
8OYL
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BU of 8oyl by Molmil
Coiled-Coil Domain of Human STIL, Q729L Mutant
分子名称: CADMIUM ION, CHLORIDE ION, SCL-interrupting locus protein, ...
著者Martin, F.J.O, Shamir, M, Woolfson, D.N, Friedler, A.
登録日2023-05-05
公開日2023-10-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Molecular Mechanism of STIL Coiled-Coil Domain Oligomerization.
Int J Mol Sci, 24, 2023
6C5A
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Human UDP-Glucose Dehydrogenase with UDP- Glc and NADH bound
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, DIMETHYL SULFOXIDE, UDP-glucose 6-dehydrogenase, ...
著者Gross, P.G, Fallah, J, Wood, Z.A.
登録日2018-01-15
公開日2019-01-16
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The A225L Substitution of hUGDH alters structure and function
To Be Published
8VJ1
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Structure of C-terminal domain of telomere resolvase, ResT, from Borrelia garinii
分子名称: Telomere resolvase ResT
著者Semper, C, Savchenko, A, Watanabe, N, Center for Structural Biology of Infectious Diseases (CSBID)
登録日2024-01-05
公開日2024-07-17
最終更新日2024-08-28
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Structure analysis of the telomere resolvase from the Lyme disease spirochete Borrelia garinii reveals functional divergence of its C-terminal domain.
Nucleic Acids Res., 52, 2024
7XPN
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Structure of the Spring Viraemia of Carp Virus Nucleoprotein
分子名称: Nucleoprotein
著者Wang, Z.X, Liu, B, Zhang, Y.A, Ouyang, S.Y.
登録日2022-05-04
公開日2023-05-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.98 Å)
主引用文献Structure of the Spring Viraemia of Carp Virus Ribonucleoprotein Complex Reveals Its Assembly Mechanism and Application in Antiviral Drug Screening.
J.Virol., 97, 2023
3MB2
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Kinetic and Structural Characterization of a Heterohexamer 4-Oxalocrotonate Tautomerase from Chloroflexus aurantiacus J-10-fl: Implications for Functional and Structural Diversity in the Tautomerase Superfamily
分子名称: 4-oxalocrotonate tautomerase family enzyme - alpha subunit, 4-oxalocrotonate tautomerase family enzyme - beta subunit, SULFATE ION
著者Burks, E.A, Fleming, C.D, Mesecar, A.D, Whitman, C.P, Pegan, S.D.
登録日2010-03-24
公開日2010-06-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Kinetic and structural characterization of a heterohexamer 4-oxalocrotonate tautomerase from Chloroflexus aurantiacus J-10-fl: implications for functional and structural diversity in the tautomerase superfamily
Biochemistry, 49, 2010
4RS3
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Crystal structure of carbohydrate transporter A0QYB3 from Mycobacterium smegmatis str. MC2 155, target EFI-510969, in complex with xylitol
分子名称: ABC transporter, carbohydrate uptake transporter-2 (CUT2) family, periplasmic sugar-binding protein, ...
著者Patskovsky, Y, Toro, R, Bhosle, R, Al Obaidi, N, Morisco, L.L, Wasserman, S.R, Chamala, S, Attonito, J.D, Scott Glenn, A, Chowdhury, S, Lafleur, J, Hillerich, B, Siedel, R.D, Love, J, Whalen, K.L, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI)
登録日2014-11-06
公開日2014-11-19
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献A General Strategy for the Discovery of Metabolic Pathways: d-Threitol, l-Threitol, and Erythritol Utilization in Mycobacterium smegmatis.
J.Am.Chem.Soc., 137, 2015
6BWC
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X-ray structure of Pen from Bacillus thuringiensis
分子名称: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Polysaccharide biosynthesis protein CapD, SULFATE ION, ...
著者Delvaux, N.A, Thoden, J.B, Holden, H.M.
登録日2017-12-14
公開日2018-01-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Molecular architectures of Pen and Pal: Key enzymes required for CMP-pseudaminic acid biosynthesis in Bacillus thuringiensis.
Protein Sci., 27, 2018

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件を2024-09-11に公開中

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