Crystal structure of carbohydrate transporter A0QYB3 from Mycobacterium smegmatis str. MC2 155, target EFI-510969, in complex with xylitol

Summary for 4RS3

DescriptorABC transporter, carbohydrate uptake transporter-2 (CUT2) family, periplasmic sugar-binding protein, Xylitol, ZINC ION, ... (7 entities in total)
Functional Keywordssugar transporter, abc-type, enzyme function initiative, efi, structural genomics, transport protein, hydrolase
Biological sourceMycobacterium smegmatis str. MC2 155
Cellular locationCell membrane ; Lipid-anchor  A0QYB3
Total number of polymer chains1
Total molecular weight36556.72
Primary citation
Huang, H.,Carter, M.S.,Vetting, M.W.,Al-Obaidi, N.,Patskovsky, Y.,Almo, S.C.,Gerlt, J.A.
A General Strategy for the Discovery of Metabolic Pathways: d-Threitol, l-Threitol, and Erythritol Utilization in Mycobacterium smegmatis.
J.Am.Chem.Soc., 137:14570-14573, 2015
PubMed: 26560079 (PDB entries with the same primary citation)
DOI: 10.1021/jacs.5b08968
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.1713 0.3% 0.8% 0.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-21