1TDQ
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![BU of 1tdq by Molmil](/molmil-images/mine/1tdq) | Structural basis for the interactions between tenascins and the C-type lectin domains from lecticans: evidence for a cross-linking role for tenascins | 分子名称: | Aggrecan core protein, CALCIUM ION, Tenascin-R | 著者 | Lundell, A, Olin, A.I, Moergelin, M, al-Karadaghi, S, Aspberg, A, Logan, D.T. | 登録日 | 2004-05-24 | 公開日 | 2004-08-31 | 最終更新日 | 2021-03-31 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis for interactions between tenascins and lectican C-type lectin domains: evidence for a crosslinking role for tenascins Structure, 12, 2004
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7T4M
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![BU of 7t4m by Molmil](/molmil-images/mine/7t4m) | Structure of dodecameric unphosphorylated Pediculus humanus (Ph) PINK1 D357A mutant | 分子名称: | Serine/threonine-protein kinase PINK1, putative | 著者 | Gan, Z.Y, Leis, A, Dewson, G, Glukhova, A, Komander, D. | 登録日 | 2021-12-10 | 公開日 | 2022-01-12 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (2.48 Å) | 主引用文献 | Activation mechanism of PINK1. Nature, 602, 2022
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4R30
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5JSV
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![BU of 5jsv by Molmil](/molmil-images/mine/5jsv) | tRNA guanine Transglycosylase (TGT) in co-crystallized complex with 6-amino-2-((((3aR,4R,6R,6aR)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl)amino)-1H-imidazo[4,5-g]quinazolin-8(7H)-one | 分子名称: | CHLORIDE ION, GLYCEROL, Queuine tRNA-ribosyltransferase, ... | 著者 | Ehrmann, F.R, Nguyen, D, Heine, A, Klebe, G. | 登録日 | 2016-05-09 | 公開日 | 2017-05-24 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.17 Å) | 主引用文献 | Application of carbohydrates based lin-benzoguanines in a solvent-exposed subpocket of the tRNA-modifying Enzyme TGT To be Published
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1TFT
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![BU of 1tft by Molmil](/molmil-images/mine/1tft) | NMR Structure of an Antagonists of the XIAP-Caspase-9 Interaction Complexed to the BIR3 domain of XIAP | 分子名称: | 1-[3,3-DIMETHYL-2-(2-METHYLAMINO-PROPIONYLAMINO)-BUTYRYL]-4-PHENOXY-PYRROLIDINE-2-CARBOXYLIC ACID(1,2,3,4-TETRAHYDRO-NAPHTHALEN-1-YL)-AMIDE, Baculoviral IAP repeat-containing protein 4, ZINC ION | 著者 | Oost, T.K, Sun, C, Armstrong, R.C, Al-Assaad, A.S, Betz, S.F, Deckwerth, T.L, Elmore, S.W, Meadows, R.P, Olejniczak, E.T, Oleksijew, A.K, Oltersdorf, T, Rosenberg, S.H, Shoemaker, A.R, Zou, H, Fesik, S.W. | 登録日 | 2004-05-27 | 公開日 | 2005-05-03 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Discovery of potent antagonists of the antiapoptotic protein XIAP for the treatment of cancer. J.Med.Chem., 47, 2004
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5JUZ
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![BU of 5juz by Molmil](/molmil-images/mine/5juz) | Crystal structure of human FPPS in complex with an allosteric inhibitor CL-06-057 | 分子名称: | CHLORIDE ION, Farnesyl pyrophosphate synthase, [(R)-(2,3-dihydro-1-benzofuran-5-yl){[6-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-yl]amino}methyl]phosphonic acid | 著者 | Park, J, Magder, A, Leung, C.Y, Tsantrizos, Y.S, Berghuis, A.M. | 登録日 | 2016-05-10 | 公開日 | 2017-03-15 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Pharmacophore Mapping of Thienopyrimidine-Based Monophosphonate (ThP-MP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase. J. Med. Chem., 60, 2017
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5JV2
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![BU of 5jv2 by Molmil](/molmil-images/mine/5jv2) | Crystal structure of human FPPS in complex with an allosteric inhibitor MIT-01-055 | 分子名称: | CHLORIDE ION, Farnesyl pyrophosphate synthase, PHOSPHATE ION, ... | 著者 | Park, J, Magder, A, Tsakos, M, Tsantrizos, Y.S, Berghuis, A.M. | 登録日 | 2016-05-10 | 公開日 | 2017-03-15 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Pharmacophore Mapping of Thienopyrimidine-Based Monophosphonate (ThP-MP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase. J. Med. Chem., 60, 2017
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1TJ1
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![BU of 1tj1 by Molmil](/molmil-images/mine/1tj1) | Crystal structure of E. coli PutA proline dehydrogenase domain (residues 86-669) complexed with L-lactate | 分子名称: | (2S)-2-HYDROXYPROPANOIC ACID, Bifunctional putA protein, FLAVIN-ADENINE DINUCLEOTIDE | 著者 | Tanner, J.J, Zhang, M, White, T.A, Schuermann, J.P, Baban, B.A, Becker, D.F. | 登録日 | 2004-06-03 | 公開日 | 2004-10-26 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structures of the Escherichia coli PutA proline dehydrogenase domain in complex with competitive inhibitors Biochemistry, 43, 2004
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7ZHC
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![BU of 7zhc by Molmil](/molmil-images/mine/7zhc) | Moss spermine/spermidine acetyl transferase (PpSSAT) in complex with AcetylCoA and polyethylen glycol | 分子名称: | ACETYL COENZYME *A, GLYCEROL, N-acetyltransferase domain-containing protein, ... | 著者 | Morera, S, Kopecny, D, Vigouroux, A. | 登録日 | 2022-04-06 | 公開日 | 2023-03-15 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.819 Å) | 主引用文献 | Biochemical and structural basis of polyamine, lysine and ornithine acetylation catalyzed by spermine/spermidine N-acetyl transferase in moss and maize. Plant J., 114, 2023
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5D9D
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![BU of 5d9d by Molmil](/molmil-images/mine/5d9d) | Luciferin-regenerating enzyme solved by SAD using synchrotron radiation at room temperature | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Luciferin regenerating enzyme, MAGNESIUM ION, ... | 著者 | Yamashita, K, Pan, D, Okuda, T, Murai, T, Kodan, A, Yamaguchi, T, Gomi, K, Kajiyama, N, Kato, H, Ago, H, Yamamoto, M, Nakatsu, T. | 登録日 | 2015-08-18 | 公開日 | 2015-09-23 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.701 Å) | 主引用文献 | An isomorphous replacement method for efficient de novo phasing for serial femtosecond crystallography. Sci Rep, 5, 2015
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1T67
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![BU of 1t67 by Molmil](/molmil-images/mine/1t67) | Crystal Structure of Human HDAC8 complexed with MS-344 | 分子名称: | 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, Histone deacetylase 8, SODIUM ION, ... | 著者 | Somoza, J.R, Skene, R.J, Katz, B.A, Mol, C, Ho, J.D, Jennings, A.J, Luong, C, Arvai, A, Buggy, J.J, Chi, E, Tang, J, Sang, B.-C, Verner, E, Wynands, R, Leahy, E.M, Dougan, D.R, Snell, G, Navre, M, Knuth, M.W, Swanson, R.V, McRee, D.E, Tari, L.W. | 登録日 | 2004-05-05 | 公開日 | 2004-07-27 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Structural Snapshots of Human HDAC8 Provide Insights into the Class I Histone Deacetylases Structure, 12, 2004
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1TK8
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![BU of 1tk8 by Molmil](/molmil-images/mine/1tk8) | T7 DNA polymerase ternary complex with 8 oxo guanosine and dAMP at the elongation site | 分子名称: | 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-D(*CP*CP*CP*AP*(8OG)P*TP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', ... | 著者 | Brieba, L.G, Eichman, B.F, Kokoska, R.J, Doublie, S, Kunkel, T.A, Ellenberger, T. | 登録日 | 2004-06-08 | 公開日 | 2004-08-31 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for the dual coding potential of 8-oxoguanosine by a high-fidelity DNA polymerase. Embo J., 23, 2004
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1JN6
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![BU of 1jn6 by Molmil](/molmil-images/mine/1jn6) | Crystal Structure of Fab-Estradiol Complexes | 分子名称: | monoclonal anti-estradiol 10G6D6 Fab heavy chain, monoclonal anti-estradiol 10G6D6 Fab light chain | 著者 | Monnet, C, Bettsworth, F, Stura, E.A, Le Du, M.-H, Menez, R, Derrien, L, Zinn-Justin, S, Gilquin, B, Sibai, G, Battail-Poirot, N, Jolivet, M, Menez, A, Arnaud, M, Ducancel, F, Charbonnier, J.B. | 登録日 | 2001-07-23 | 公開日 | 2002-02-06 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Highly specific anti-estradiol antibodies: structural characterisation and binding diversity. J.Mol.Biol., 315, 2002
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4R7J
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![BU of 4r7j by Molmil](/molmil-images/mine/4r7j) | Crystal Structure of Inosine 5'-monophosphate Dehydrogenase with the Internal Deletion Containing CBS Domain from Campylobacter jejuni | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, GLYCEROL, ... | 著者 | Kim, Y, Makowska-Grzyska, M, Gu, M, Hedstrom, L, Anderson, W.F, Joachimiak, A, CSGID, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2014-08-27 | 公開日 | 2014-09-17 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.1172 Å) | 主引用文献 | Crystal Structure of Inosine 5'-monophosphate Dehydrogenase with the Internal Deletion Containing CBS Domain from Campylobacter jejuni To be Published, 2014
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5JWD
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![BU of 5jwd by Molmil](/molmil-images/mine/5jwd) | Crystal structure of H-2Db in complex with the LCMV-derived GP392-401 peptide | 分子名称: | Beta-2-microglobulin, GLYCEROL, H-2 class I histocompatibility antigen, ... | 著者 | Buratto, J, Badia-Martinez, D, Norstrom, M, Sandalova, T, Achour, A. | 登録日 | 2016-05-12 | 公開日 | 2017-05-24 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structures of H-2Db in complex with the LCMV-derived peptides GP92 and GP392 explain pleiotropic effects of glycosylation on antigen presentation and immunogenicity. PLoS ONE, 12, 2017
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7ZKT
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![BU of 7zkt by Molmil](/molmil-images/mine/7zkt) | Moss spermine/spermidine acetyl transferase (PpSSAT) in complex with CoA and lysine | 分子名称: | 1,2-ETHANEDIOL, COENZYME A, LYSINE, ... | 著者 | Morera, S, Kopecny, D, Vigouroux, A, Briozzo, P. | 登録日 | 2022-04-13 | 公開日 | 2023-03-22 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Biochemical and structural basis of polyamine, lysine and ornithine acetylation catalyzed by spermine/spermidine N-acetyl transferase in moss and maize. Plant J., 114, 2023
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7AQX
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6WA3
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![BU of 6wa3 by Molmil](/molmil-images/mine/6wa3) | Solution NMR structure of the myristoylated feline immunodeficiency virus matrix protein | 分子名称: | MYRISTIC ACID, Matrix protein | 著者 | Brown, J.B, Summers, H.R, Brown, L.A, Marchant, J, Canova, P.N, O'Hern, C.T, Abbott, S, Nyaunu, C, Maxwell, S, Johnson, T, Moser, M, Ablan, S.D, Carter, H, Freed, E.O, Summers, M.F. | 登録日 | 2020-03-24 | 公開日 | 2020-07-22 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural and Mechanistic Studies of the Rare Myristoylation Signal of the Feline Immunodeficiency Virus. J.Mol.Biol., 432, 2020
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7AQZ
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![BU of 7aqz by Molmil](/molmil-images/mine/7aqz) | Co-Crystal Structure of Variant Surface Glycoprotein VSG2 in complex with Nanobody VSG2(NB14) | 分子名称: | CITRIC ACID, Nanobody VSG2(NB14), SODIUM ION, ... | 著者 | Stebbins, C.E, Hempelmann, A, VanStraaten, M. | 登録日 | 2020-10-23 | 公開日 | 2021-11-03 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Nanobody-mediated macromolecular crowding induces membrane fission and remodeling in the African trypanosome. Cell Rep, 37, 2021
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6IDP
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![BU of 6idp by Molmil](/molmil-images/mine/6idp) | Crystal structure of Vibrio cholerae MATE transporter VcmN in the straight form | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, MATE family efflux transporter | 著者 | Kusakizako, T, Claxton, D.P, Tanaka, Y, Maturana, A.D, Kuroda, T, Ishitani, R, Mchaourab, H.S, Nureki, O. | 登録日 | 2018-09-11 | 公開日 | 2019-01-16 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.205 Å) | 主引用文献 | Structural Basis of H+-Dependent Conformational Change in a Bacterial MATE Transporter. Structure, 27, 2019
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5K1P
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6PPA
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![BU of 6ppa by Molmil](/molmil-images/mine/6ppa) | Crystal structure of the unliganded bromodomain of human BRD7 | 分子名称: | 1,2-ETHANEDIOL, Bromodomain-containing protein 7, PHOSPHATE ION | 著者 | Chan, A, Karim, M.R, Zhu, J, Schonbrunn, E. | 登録日 | 2019-07-05 | 公開日 | 2020-03-11 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Structural Basis of Inhibitor Selectivity in the BRD7/9 Subfamily of Bromodomains. J.Med.Chem., 63, 2020
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4QT6
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![BU of 4qt6 by Molmil](/molmil-images/mine/4qt6) | Crystal structure of the SPRY domain of human HERC1 | 分子名称: | FORMAMIDE, Probable E3 ubiquitin-protein ligase HERC1, UNKNOWN ATOM OR ION | 著者 | Dong, A, Hu, J, Guan, X, Wernimont, A, Li, Y, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) | 登録日 | 2014-07-07 | 公開日 | 2015-01-07 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Crystal structure of the SPRY domain of human HERC1 To be Published
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1TF2
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4V3R
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![BU of 4v3r by Molmil](/molmil-images/mine/4v3r) | Designed armadillo repeat protein with 5 internal repeats, 2nd generation C-cap and 3rd generation N-cap. | 分子名称: | MAGNESIUM ION, YIII_M5_AII | 著者 | Reichen, C, Madhurantakam, C, Pluckthun, A, Mittl, P. | 登録日 | 2014-10-20 | 公開日 | 2016-01-13 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structures of Designed Armadillo-Repeat Proteins Show Propagation of Inter-Repeat Interface Effects Acta Crystallogr.,Sect.D, 72, 2016
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