5HZP
| Structure of human C4b-binding protein alpha chain CCP domains 1 and 2 in complex with the hypervariable region of group A Streptococcus M49 protein. | 分子名称: | C4b-binding protein alpha chain, M protein, serotype 49, ... | 著者 | Buffalo, C.Z, Bahn-Suh, A.J, Ghosh, P. | 登録日 | 2016-02-02 | 公開日 | 2016-07-20 | 最終更新日 | 2019-12-11 | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | 主引用文献 | Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein. Nat Microbiol, 1, 2016
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5HJR
| Murine endoplasmic reticulum alpha-glucosidase II with bound covalent intermediate | 分子名称: | 1,2-ETHANEDIOL, 5-fluoro-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Caputo, A.T, Roversi, P, Alonzi, D.S, Kiappes, J.L, Zitzmann, N. | 登録日 | 2016-01-13 | 公開日 | 2016-07-27 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structures of mammalian ER alpha-glucosidase II capture the binding modes of broad-spectrum iminosugar antivirals. Proc.Natl.Acad.Sci.USA, 113, 2016
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5HFB
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6HK3
| Crystal structure of GSK-3B in complex with pyrazine inhibitor C44 | 分子名称: | 3-azanyl-~{N}-(2-methoxyphenyl)-6-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]pyrazine-2-carboxamide, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | 著者 | Piretti, V, Giabbai, B, Demitri, N, Di Martino, R, Tripathi, S.K, Gobbo, D, Decherchi, S, Storici, P, Girotto, S, Cavalli, A. | 登録日 | 2018-09-05 | 公開日 | 2019-07-17 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Investigating Drug-Target Residence Time in Kinases through Enhanced Sampling Simulations. J Chem Theory Comput, 15, 2019
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6PXK
| 3.65 Angstroms resolution structure of HslU with an axial-channel plug | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent protease ATPase subunit HslU, SULFATE ION, ... | 著者 | Baytshtok, V, Grant, R.A, Sauer, R.T. | 登録日 | 2019-07-26 | 公開日 | 2020-07-29 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.647 Å) | 主引用文献 | Heat activates the AAA+ HslUV protease by melting an axial autoinhibitory plug. Cell Rep, 34, 2021
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8OOT
| CryoEM Structure INO80core Hexasome complex Arp5 Ies6 refinement state2 | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 5, Chromatin-remodeling complex subunit IES6, ... | 著者 | Zhang, M, Jungblut, A, Hoffmann, T, Eustermann, S. | 登録日 | 2023-04-05 | 公開日 | 2023-07-26 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | 主引用文献 | Hexasome-INO80 complex reveals structural basis of noncanonical nucleosome remodeling. Science, 381, 2023
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7RXG
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8GJB
| L-threonine 3-Dehydrogenase from Trypanosoma cruzi in complex with NAD and acetate | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, GLYCEROL, ... | 著者 | Mercaldi, G.F, Faria, J.N, Fagundes, M, Bezerra, E.H.S, Cordeiro, A.T. | 登録日 | 2023-03-15 | 公開日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structure, allosteric regulation and metabolic activity of L-threonine 3-Dehydrogenase from Trypanosoma cruzi To Be Published
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6Y7L
| Structure of the BRD9 bromodomain and TP-472 | 分子名称: | 3-(6-acetylpyrrolo[1,2-a]pyrimidin-8-yl)-N-cyclopropyl-4-methylbenzamide, Bromodomain-containing protein 9 | 著者 | Diaz-Saez, L, Krojer, T, Picaud, S, von Delft, F, Filippakopoulos, P, Arrowsmith, C.H, Edwards, A, Bountra, C, Huber, K.V.M. | 登録日 | 2020-03-01 | 公開日 | 2021-03-31 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure of the BRD9 bromodomain and compound 2 To Be Published
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5HGP
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8H24
| Leucine-rich alpha-2-glycoprotein 1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Leucine-rich alpha-2-glycoprotein, SULFATE ION | 著者 | Won, S.Y, Park, B.S, Lee, D.S, Kim, H.M, Han, A, Yang, J. | 登録日 | 2022-10-04 | 公開日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Crystal structure of LRG1 and the functional significance of LRG1 glycan for LPHN2 activation. Exp.Mol.Med., 55, 2023
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5K56
| Human muscle fructose-1,6-bisphosphatase in active R-state in complex with fructose-1,6-bisphosphate | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase isozyme 2 | 著者 | Barciszewski, J, Wisniewski, J, Kolodziejczyk, R, Dzugaj, A, Jaskolski, M, Rakus, D. | 登録日 | 2016-05-23 | 公開日 | 2017-06-07 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.198 Å) | 主引用文献 | Structural studies of human muscle FBPase To Be Published
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6Y9H
| Thrombin in complex with D-Phe-Pro-m-Trifluoromethylbenzylamide derivative (phe2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, D-Phe-Pro-m-Trifluoromethylbenzylamide derivative (phe2), DIMETHYL SULFOXIDE, ... | 著者 | Sandner, A, Heine, A, Klebe, G, Abazi, N. | 登録日 | 2020-03-09 | 公開日 | 2021-03-31 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Thrombin in complex with D-Phe-Pro-m-Trifluoromethylbenzylamide derivative (phe2) To be published
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6MTP
| Crystal structure of VRC42.04 Fab in complex with gp41 peptide | 分子名称: | Antibody VRC42.04 Fab heavy chain, Antibody VRC42.04 Fab light chain, RV217 founder virus gp41 peptide | 著者 | Kwon, Y.D, Druz, A, Law, W.H, Peng, D, Zhang, B, Doria-Rose, N.A, Kwong, P.D. | 登録日 | 2018-10-21 | 公開日 | 2019-03-27 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.036 Å) | 主引用文献 | Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual. Immunity, 50, 2019
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7K5G
| 1.95 A resolution structure of WT BfrB from Pseudomonas aeruginosa in complex with a protein-protein interaction inhibitor KM-5-28 | 分子名称: | 4-{[3-(2-hydroxyphenyl)propyl]amino}-1H-isoindole-1,3(2H)-dione, Ferroxidase, POTASSIUM ION, ... | 著者 | Lovell, S, Battaile, K.P, Soldano, A, Punchi-Hewage, A, Meraz, K, Annor-Gyamfi, J.K, Yao, H, Bunce, R.A, Rivera, M. | 登録日 | 2020-09-16 | 公開日 | 2020-12-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Small Molecule Inhibitors of the Bacterioferritin (BfrB)-Ferredoxin (Bfd) Complex Kill Biofilm-Embedded Pseudomonas aeruginosa Cells. Acs Infect Dis., 7, 2021
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4ZRP
| TC:CD320 | 分子名称: | CALCIUM ION, CD320 antigen, CYANOCOBALAMIN, ... | 著者 | Alam, A, Locher, K.P. | 登録日 | 2015-05-12 | 公開日 | 2016-07-20 | 最終更新日 | 2021-08-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis of transcobalamin recognition by human CD320 receptor. Nat Commun, 7, 2016
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6Q63
| BT0459 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-hexosaminidase, CALCIUM ION, ... | 著者 | Basle, A, Crouch, L, Bolam, D. | 登録日 | 2018-12-10 | 公開日 | 2019-05-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | Complex N-glycan breakdown by gut Bacteroides involves an extensive enzymatic apparatus encoded by multiple co-regulated genetic loci. Nat Microbiol, 4, 2019
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8OQW
| Crystal structure of Tannerella forsythia MurNAc kinase MurK | 分子名称: | ATPase, GLYCEROL, SULFATE ION | 著者 | Gogler, K, Fink, P, Stasiak, A.C, Stehle, T, Zocher, G. | 登録日 | 2023-04-12 | 公開日 | 2023-08-02 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | N-acetylmuramic acid recognition by MurK kinase from the MurNAc auxotrophic oral pathogen Tannerella forsythia. J.Biol.Chem., 299, 2023
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7TL3
| Crystal Structure of Yeast p58C Multi-Tyrosine Mutant 5YF431 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, IRON/SULFUR CLUSTER | 著者 | Blee, A.M, Salay, L.E, Chazin, W.J. | 登録日 | 2022-01-18 | 公開日 | 2022-06-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.066 Å) | 主引用文献 | Modification of the 4Fe-4S Cluster Charge Transport Pathway Alters RNA Synthesis by Yeast DNA Primase. Biochemistry, 61, 2022
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4ZMR
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8OOC
| CryoEM Structure INO80core Hexasome complex Rvb core refinement state1 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Chromatin-remodeling ATPase Ino80, ... | 著者 | Zhang, M, Jungblut, A, Hoffmann, T, Eustermann, S. | 登録日 | 2023-04-05 | 公開日 | 2023-08-02 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | 主引用文献 | Hexasome-INO80 complex reveals structural basis of noncanonical nucleosome remodeling. Science, 381, 2023
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8F5U
| Rabbit muscle pyruvate kinase in complex with magnesium, potassium and pyruvate | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, ... | 著者 | Holyoak, T, Fenton, A.W. | 登録日 | 2022-11-15 | 公開日 | 2023-05-24 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | PYK-SubstitutionOME: an integrated database containing allosteric coupling, ligand affinity and mutational, structural, pathological, bioinformatic and computational information about pyruvate kinase isozymes. Database (Oxford), 2023, 2023
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8OW7
| Crystal structure of Tannerella forsythia sugar kinase K1058 in complex with N-acetylmuramic acid (MurNAc) | 分子名称: | N-acetyl-beta-muramic acid, N-acetylglucosamine kinase, SULFATE ION | 著者 | Stasiak, A.C, Gogler, K, Fink, P, Stehle, T, Zocher, G. | 登録日 | 2023-04-27 | 公開日 | 2023-08-02 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.06 Å) | 主引用文献 | N-acetylmuramic acid recognition by MurK kinase from the MurNAc auxotrophic oral pathogen Tannerella forsythia. J.Biol.Chem., 299, 2023
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8RKR
| Structure of human DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE (ALDH4A1) complexed with a monophosphate-tweezer | 分子名称: | (1R,5S,9S,16R,20R,24S,28S,35R)-22-(Dihydroxyphosphoryloxy)tridecacyclo[22.14.1.15,20.19,16.128,35.02,23.04,21.06,19.08,17.010,15.025,38.027,36.029,34]dotetraconta-2(23),3,6,8(17),10,12,14,18,21,25,27(36),29,31,33,37-pentadecaen-3-ol, BENZOIC ACID, Delta-1-pyrroline-5-carboxylate dehydrogenase, ... | 著者 | Porfetye, A.T, Vetter, I.R. | 登録日 | 2023-12-28 | 公開日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | How Do Molecular Tweezers Bind to Proteins? Lessons from X-ray Crystallography. Molecules, 29, 2024
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7JMF
| Functional Pathways of Biomolecules Retrieved from Single-particle Snapshots - Frame 42 - State 6 (S6) | 分子名称: | CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ZINC ION, ... | 著者 | Dashti, A, des Georges, A, Frank, J, Ourmazd, A. | 登録日 | 2020-07-31 | 公開日 | 2020-08-12 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Retrieving functional pathways of biomolecules from single-particle snapshots. Nat Commun, 11, 2020
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