7X3J
| Cryo-EM structure of human TRiC-tubulin-S2 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, ... | Authors: | Cong, Y, Liu, C.X. | Deposit date: | 2022-03-01 | Release date: | 2023-06-07 | Last modified: | 2023-07-05 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM. Commun Biol, 6, 2023
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7X6Q
| cryo-EM structure of human TRiC-ATP-closed state | Descriptor: | T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ... | Authors: | Cong, Y, Liu, C.X. | Deposit date: | 2022-03-08 | Release date: | 2023-06-07 | Last modified: | 2023-07-05 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM. Commun Biol, 6, 2023
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7X7Y
| Cryo-EM structure of Human TRiC-ATP-open state | Descriptor: | T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ... | Authors: | Cong, Y, Liu, C.X. | Deposit date: | 2022-03-10 | Release date: | 2023-06-07 | Last modified: | 2023-07-05 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM. Commun Biol, 6, 2023
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7Y9N
| an engineered 5-helix bundle derived from SARS-CoV-2 S2 in complex with HR2P | Descriptor: | SARS-coV-2 S2 subunit, Spike protein S2',5HB-H2 | Authors: | Lu, G.W, Lin, X, Guo, L.Y, Lin, S. | Deposit date: | 2022-06-25 | Release date: | 2022-08-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.885 Å) | Cite: | An engineered 5-helix bundle derived from SARS-CoV-2 S2 pre-binds sarbecoviral spike at both serological- and endosomal-pH to inhibit virus entry. Emerg Microbes Infect, 11, 2022
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7YTU
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7YTT
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7YLY
| yeast TRiC-plp2 complex at S5 closed TRiC state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | Authors: | Han, W.Y. | Deposit date: | 2022-07-27 | Release date: | 2023-03-29 | Method: | ELECTRON MICROSCOPY (3.05 Å) | Cite: | Structural basis of plp2-mediated cytoskeletal protein folding by TRiC/CCT. Sci Adv, 9, 2023
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7YLV
| yeast TRiC-plp2-substrate complex at S2 ATP binding state | Descriptor: | Phosducin-like protein 2, T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, ... | Authors: | Han, W.Y. | Deposit date: | 2022-07-27 | Release date: | 2023-03-29 | Method: | ELECTRON MICROSCOPY (3.91 Å) | Cite: | Structural basis of plp2-mediated cytoskeletal protein folding by TRiC/CCT. Sci Adv, 9, 2023
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7YLW
| yeast TRiC-plp2-tubulin complex at S3 closed TRiC state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Han, W.Y. | Deposit date: | 2022-07-27 | Release date: | 2023-03-29 | Method: | ELECTRON MICROSCOPY (3.39 Å) | Cite: | Structural basis of plp2-mediated cytoskeletal protein folding by TRiC/CCT. Sci Adv, 9, 2023
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7YLU
| yeast TRiC-plp2-substrate complex at S1 TRiC-NPP state | Descriptor: | Phosducin-like protein 2, T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, ... | Authors: | Han, W.Y. | Deposit date: | 2022-07-27 | Release date: | 2023-03-29 | Method: | ELECTRON MICROSCOPY (4.55 Å) | Cite: | Structural basis of plp2-mediated cytoskeletal protein folding by TRiC/CCT. Sci Adv, 9, 2023
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7YLX
| yeast TRiC-plp2-actin complex at S4 closed TRiC state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | Authors: | Han, W.Y. | Deposit date: | 2022-07-27 | Release date: | 2023-03-29 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis of plp2-mediated cytoskeletal protein folding by TRiC/CCT. Sci Adv, 9, 2023
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6AKY
| The Crystal structure of Human Chemokine Receptor CCR5 in complex with compound 34 | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 4,4-difluoro-N-[(1S)-3-{(3-exo)-3-[3-methyl-5-(propan-2-yl)-4H-1,2,4-triazol-4-yl]-8-azabicyclo[3.2.1]octan-8-yl}-1-(thiophen-3-yl)propyl]cyclohexane-1-carboxamide, C-C chemokine receptor type 5,Rubredoxin,C-C chemokine receptor type 5, ... | Authors: | Zhu, Y, Zhao, Q, Wu, B. | Deposit date: | 2018-09-04 | Release date: | 2018-10-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure-Based Design of 1-Heteroaryl-1,3-propanediamine Derivatives as a Novel Series of CC-Chemokine Receptor 5 Antagonists. J. Med. Chem., 61, 2018
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6AKX
| The Crystal structure of Human Chemokine Receptor CCR5 in complex with compound 21 | Descriptor: | C-C chemokine receptor type 5,Rubredoxin,C-C chemokine receptor type 5, N-[(1S)-3-{(3-exo)-3-[3-methyl-5-(propan-2-yl)-4H-1,2,4-triazol-4-yl]-8-azabicyclo[3.2.1]octan-8-yl}-1-(thiophen-2-yl)propyl]cyclopentanecarboxamide, NITRATE ION, ... | Authors: | Zhu, Y, Zhao, Q, Wu, B. | Deposit date: | 2018-09-04 | Release date: | 2018-10-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure-Based Design of 1-Heteroaryl-1,3-propanediamine Derivatives as a Novel Series of CC-Chemokine Receptor 5 Antagonists. J. Med. Chem., 61, 2018
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