4QBE
| The second sphere residue T263 is important for function and activity of PTP1B through modulating WPD loop | 分子名称: | Tyrosine-protein phosphatase non-receptor type 1 | 著者 | Xiao, P, Wang, X, Wang, H.M, Fu, X.L, Cui, F.A, Yu, X, Bi, W.X. | 登録日 | 2014-05-08 | 公開日 | 2014-12-24 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.292 Å) | 主引用文献 | The second-sphere residue T263 is important for the function and catalytic activity of PTP1B via interaction with the WPD-loop Int.J.Biochem.Cell Biol., 57C, 2014
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4QBW
| The second sphere residue T263 is important for function and activity of PTP1B through modulating WPD loop | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1 | 著者 | Xiao, P, Wang, X, Wang, H.M, Fu, X.L, Cui, F.A, Yu, X, Bi, W.X, Sun, J.P. | 登録日 | 2014-05-08 | 公開日 | 2015-02-11 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.912 Å) | 主引用文献 | The second-sphere residue T263 is important for the function and catalytic activity of PTP1B via interaction with the WPD-loop Int.J.Biochem.Cell Biol., 57, 2014
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4QAP
| The second sphere residue T263 is important for function and activity of PTP1B through modulating WPD loop | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1 | 著者 | Xiao, P, Wang, X, Wang, H.M, Fu, X.L, Cui, F.A, Yu, X, Bi, W.X, Sun, J.P. | 登録日 | 2014-05-05 | 公開日 | 2015-02-11 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.903 Å) | 主引用文献 | The second-sphere residue T263 is important for the function and catalytic activity of PTP1B via interaction with the WPD-loop Int.J.Biochem.Cell Biol., 57, 2014
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5UZB
| Cryo-EM structure of the MAL TIR domain filament | 分子名称: | Toll/interleukin-1 receptor domain-containing adapter protein | 著者 | Ve, T, Vajjhala, P.R, Hedger, A, Croll, T, DiMaio, F, Horsefield, S, Yu, X, Lavrencic, P, Hassan, Z, Morgan, G.P, Mansell, A, Mobli, M, O'Carrol, A, Chauvin, B, Gambin, Y, Sierecki, E, Landsberg, M.J, Stacey, K.J, Egelman, E.H, Kobe, B. | 登録日 | 2017-02-25 | 公開日 | 2017-07-26 | 最終更新日 | 2020-01-15 | 実験手法 | ELECTRON MICROSCOPY (7 Å) | 主引用文献 | Structural basis of TIR-domain-assembly formation in MAL- and MyD88-dependent TLR4 signaling. Nat. Struct. Mol. Biol., 24, 2017
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5VWG
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5W7G
| An envelope of a filamentous hyperthermophilic virus carries lipids in a horseshoe conformation | 分子名称: | DNA (253-MER), ORF132, ORF140 | 著者 | Kasson, P, DiMaio, F, Yu, X, Lucas-Staat, S, Krupovic, M, Schouten, S, Prangishvili, D, Egelman, E. | 登録日 | 2017-06-19 | 公開日 | 2017-07-19 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Model for a novel membrane envelope in a filamentous hyperthermophilic virus. Elife, 6, 2017
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5A2T
| The Molecular Basis for Flexibility in the Flexible Filamentous Plant Viruses | 分子名称: | BAMBOO MOSAIC VIRUS, COAT PROTEIN | 著者 | DiMaio, F, Chen, C.C, Yu, X, Frenz, B, Hsu, Y.H, Lin, N.S, Egelman, E.H. | 登録日 | 2015-05-23 | 公開日 | 2015-07-22 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (5.6 Å) | 主引用文献 | The Molecular Basis for Flexibility in the Flexible Filamentous Plant Viruses. Nat.Struct.Mol.Biol., 22, 2015
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4BYH
| Crystal structure of sialylated IgG Fc | 分子名称: | CHLORIDE ION, IG GAMMA-1 CHAIN C REGION, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Crispin, M, Yu, X, Bowden, T.A. | 登録日 | 2013-07-19 | 公開日 | 2013-08-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structure of Sialylated Igg Fc: Implications for the Mechanism of Intravenous Immunoglobulin Therapy. Proc.Natl.Acad.Sci.USA, 110, 2013
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4ICZ
| HER2 1221/1222 phosphorylation regulated by PTPN9 | 分子名称: | HER2, Tyrosine-protein phosphatase non-receptor type 9 | 著者 | Xu, Y.F, Wang, H.M, Liu, C.H, Yu, X, Sun, J.P. | 登録日 | 2012-12-11 | 公開日 | 2013-12-11 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | HER2 1221/1222 phosphorylation regulated by PTPN9 To be Published
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4E2I
| The Complex Structure of the SV40 Helicase Large T Antigen and p68 Subunit of DNA Polymerase Alpha-Primase | 分子名称: | DNA polymerase alpha subunit B, Large T antigen, ZINC ION | 著者 | Zhou, B, Arnett, D.R, Yu, X, Brewster, A, Sowd, G.A, Xie, C.L, Vila, S, Gai, D, Fanning, E, Chen, X.S. | 登録日 | 2012-03-08 | 公開日 | 2012-06-13 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (5 Å) | 主引用文献 | Structural basis for the interaction of a hexameric replicative helicase with the regulatory subunit of human DNA polymerase alpha-primase. J.Biol.Chem., 287, 2012
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4KW9
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4KW8
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4KW4
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4GFU
| PTPN18 in complex with HER2-pY1248 phosphor-peptides | 分子名称: | HER2-pY1248 phosphor-peptide, Tyrosine-protein phosphatase non-receptor type 18 | 著者 | Wang, H.M, Yang, F, Du, Y.J, Yang, D.X, Zhang, Y, Yu, X, Sun, J.P. | 登録日 | 2012-08-04 | 公開日 | 2013-08-07 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | PTPN18-HER2 peptides To be Published
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4GFV
| PTPN18 in complex with HER2-pY1196 phosphor-peptides | 分子名称: | HER2-pY1196 phosphor-peptide, Tyrosine-protein phosphatase non-receptor type 18 | 著者 | Wang, H.M, Yang, F, Du, Y.J, Yang, D.X, Zhang, Y, Yu, X, Sun, J.P. | 登録日 | 2012-08-04 | 公開日 | 2013-10-23 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.095 Å) | 主引用文献 | PTPN18-HER2 peptides To be Published
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8EYO
| Crystal Structure of Human Mitochondrial NADP+ Malic Enzyme 3 with NADP bound | 分子名称: | CITRIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADP-dependent malic enzyme, ... | 著者 | Shaffer, P.L, Grell, T.A.J, Mason, M, Thompson, A.A, Riley, D, Wagner, M.V, Steele, R, Ortiz-Meoz, R, Wadia, J, Sharma, S, Yu, X. | 登録日 | 2022-10-28 | 公開日 | 2023-02-08 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Integrative structural and functional analysis of human malic enzyme 3: A potential therapeutic target for pancreatic cancer. Heliyon, 8, 2022
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8EYN
| Crystal Structure of Human Mitochondrial NADP+ Malic Enzyme 3 in Apo Form | 分子名称: | CITRIC ACID, NADP-dependent malic enzyme, mitochondrial | 著者 | Shaffer, P.L, Grell, T.A.J, Mason, M, Thompson, A.A, Riley, D, Wagner, M.V, Steele, R, Ortiz-Meoz, R, Wadia, J, Sharma, S, Yu, X. | 登録日 | 2022-10-28 | 公開日 | 2023-02-08 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Integrative structural and functional analysis of human malic enzyme 3: A potential therapeutic target for pancreatic cancer. Heliyon, 8, 2022
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6L03
| structure of PTP-MEG2 and MUNC18-1-pY145 peptide complex | 分子名称: | Tyrosine-protein phosphatase non-receptor type 9, stxbp1-pY145 peptide | 著者 | Xu, Y.F, Chen, X, Yu, X, Sun, J.P. | 登録日 | 2019-09-25 | 公開日 | 2020-09-30 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.084 Å) | 主引用文献 | PTP-MEG2 regulates quantal size and fusion pore opening through two distinct structural bases and substrates. Embo Rep., 22, 2021
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6KZQ
| structure of PTP-MEG2 and NSF-pY83 peptide complex | 分子名称: | NSF-pY83 peptide, Tyrosine-protein phosphatase non-receptor type 9 | 著者 | Xu, Y.F, Chen, X, Yu, X, Sun, J.P. | 登録日 | 2019-09-25 | 公開日 | 2020-09-30 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | PTP-MEG2 regulates quantal size and fusion pore opening through two distinct structural bases and substrates. Embo Rep., 22, 2021
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6OGE
| Cryo-EM structure of Her2 extracellular domain-Trastuzumab Fab-Pertuzumab Fab complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Pertuzumab FAB HEAVY CHAIN, Pertuzumab FAB LIGHT CHAIN, ... | 著者 | Hao, Y, Yu, X, Bai, Y, Huang, X. | 登録日 | 2019-04-02 | 公開日 | 2019-05-15 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.36 Å) | 主引用文献 | Cryo-EM Structure of HER2-trastuzumab-pertuzumab complex. Plos One, 14, 2019
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5J8R
| Crystal Structure of the Catalytic Domain of Human Protein Tyrosine Phosphatase non-receptor Type 12 - K61R mutant | 分子名称: | Tyrosine-protein phosphatase non-receptor type 12 | 著者 | Li, H, Yang, F, Xu, Y.F, Wang, W.J, Xiao, P, Yu, X, Sun, J.P. | 登録日 | 2016-04-08 | 公開日 | 2016-04-27 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.043 Å) | 主引用文献 | Crystal structure and substrate specificity of PTPN12. Cell Rep, 15, 2016
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6NZU
| Structure of the human frataxin-bound iron-sulfur cluster assembly complex | 分子名称: | Acyl carrier protein, Cysteine desulfurase, mitochondrial, ... | 著者 | Fox, N.G, Yu, X, Xidong, F, Alain, M, Joseph, N, Claire, S.D, Christine, B, Han, S, Yue, W.W. | 登録日 | 2019-02-14 | 公開日 | 2019-05-22 | 最終更新日 | 2019-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure of the human frataxin-bound iron-sulfur cluster assembly complex provides insight into its activation mechanism. Nat Commun, 10, 2019
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5ZCJ
| Crystal structure of complex | 分子名称: | TP53-binding protein 1, Tudor-interacting repair regulator protein | 著者 | Wang, J, Yuan, Z, Cui, Y, Xie, R, Wang, M, Ma, Y, Yu, X, Liu, X. | 登録日 | 2018-02-17 | 公開日 | 2018-06-27 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.004 Å) | 主引用文献 | Crystal structure of complex To Be Published
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4RAG
| CRYSTAL STRUCTURE of PPC2A-D38K | 分子名称: | MANGANESE (II) ION, Protein phosphatase 1A | 著者 | Pan, C, Tang, J.Y, Xu, Y.F, Xiao, P, Liu, H.D, Wang, H.A, Wang, W.B, Meng, F.G, Yu, X, Sun, J.P. | 登録日 | 2014-09-10 | 公開日 | 2015-08-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | The catalytic role of the M2 metal ion in PP2C alpha Sci Rep, 5, 2015
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4R4Z
| Structure of PNGF-II in P21 space group | 分子名称: | PNGF-II | 著者 | Sun, G, Yu, X, Celimuge, Wang, L, Li, M, Gan, J, Qu, D, Ma, J, Chen, L. | 登録日 | 2014-08-20 | 公開日 | 2015-01-28 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Identification and
Characterization of a Novel Prokaryotic Peptide: N-glycosidase from
Elizabethkingia meningoseptica J.Biol.Chem., 2015
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