1GE9
| SOLUTION STRUCTURE OF THE RIBOSOME RECYCLING FACTOR | 分子名称: | RIBOSOME RECYCLING FACTOR | 著者 | Yoshida, T, Uchiyama, S, Nakano, H, Kashimori, H, Kijima, H, Ohshima, T, Saihara, Y, Ishino, T, Shimahara, T, Yoshida, T, Yokose, K, Ohkubo, T, Kaji, A, Kobayashi, Y. | 登録日 | 2000-10-19 | 公開日 | 2001-05-16 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the ribosome recycling factor from Aquifex aeolicus. Biochemistry, 40, 2001
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5C2I
| Crystal structure of Anabaena sp. DyP-type peroxidese (AnaPX) | 分子名称: | 1,2-ETHANEDIOL, ACETIC ACID, Alr1585 protein, ... | 著者 | Yoshida, T, Amano, Y, Tsuge, H, Sugano, Y. | 登録日 | 2015-06-16 | 公開日 | 2015-12-16 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Anabaena sp. DyP-type peroxidase is a tetramer consisting of two asymmetric dimers. Proteins, 84, 2016
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6KXX
| Human PPAR alpha ligand binding domain in complex with a synthetic agonist (compound A) | 分子名称: | 1-(4-chlorophenyl)-6-methyl-3-propan-2-yl-pyrazolo[3,4-b]pyridine-4-carboxylic acid, PGC1alpha, Peroxisome proliferator-activated receptor alpha | 著者 | Yoshida, T, Tachibana, K, Oki, H, Doi, M, Fukuda, S, Yuzuriha, T, Tabata, R, Ishimoto, K, Kawahara, K, Ohkubo, T, Miyachi, H, Doi, T. | 登録日 | 2019-09-14 | 公開日 | 2020-05-20 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural Basis for PPAR alpha Activation by 1H-pyrazolo-[3,4-b]pyridine Derivatives. Sci Rep, 10, 2020
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6KXY
| Human PPAR alpha ligand binding domain in complex with a synthetic agonist (compound B) | 分子名称: | 6-ethyl-1-(4-fluorophenyl)-3-pentan-3-yl-pyrazolo[3,4-b]pyridine-4-carboxylic acid, PGC1alpha, Peroxisome proliferator-activated receptor alpha | 著者 | Yoshida, T, Tachibana, K, Oki, H, Doi, M, Fukuda, S, Yuzuriha, T, Tabata, R, Ishimoto, K, Kawahara, K, Ohkubo, T, Miyachi, H, Doi, T. | 登録日 | 2019-09-14 | 公開日 | 2020-05-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural Basis for PPAR alpha Activation by 1H-pyrazolo-[3,4-b]pyridine Derivatives. Sci Rep, 10, 2020
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5ZJ4
| Guanine-specific ADP-ribosyltransferase | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ADP-ribosyltransferase | 著者 | Yoshida, T, Tsuge, H. | 登録日 | 2018-03-19 | 公開日 | 2018-08-08 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.49739277 Å) | 主引用文献 | Substrate N2atom recognition mechanism in pierisin family DNA-targeting, guanine-specific ADP-ribosyltransferase ScARP. J. Biol. Chem., 293, 2018
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5ZJ5
| Guanine-specific ADP-ribosyltransferase with NADH and GDP | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ADP-ribosyltransferase, GUANOSINE-5'-DIPHOSPHATE | 著者 | Yoshida, T, Tsuge, H. | 登録日 | 2018-03-19 | 公開日 | 2018-08-08 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.568112 Å) | 主引用文献 | Substrate N2atom recognition mechanism in pierisin family DNA-targeting, guanine-specific ADP-ribosyltransferase ScARP. J. Biol. Chem., 293, 2018
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3MM2
| Dye-decolorizing peroxidase (DyP) in complex with cyanide | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CYANIDE ION, DyP, ... | 著者 | Sugano, Y, Yoshida, T, Tsuge, H. | 登録日 | 2010-04-19 | 公開日 | 2011-04-27 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | The catalytic mechanism of dye-decolorizing peroxidase DyP may require the swinging movement of an aspartic acid residue Febs J., 278, 2011
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3MM1
| Dye-decolorizing peroxidase (DyP) D171N | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DyP, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Sugano, Y, Yoshida, T, Tsuge, H. | 登録日 | 2010-04-19 | 公開日 | 2011-04-27 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | The catalytic mechanism of dye-decolorizing peroxidase DyP may require the swinging movement of an aspartic acid residue Febs J., 278, 2011
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3MM3
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7CEE
| Crystal structure of mouse neuroligin-3 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Neuroligin-3 | 著者 | Yamagata, A, Yoshida, T, Shiroshima, T, Maeda, A, Fukai, S. | 登録日 | 2020-06-23 | 公開日 | 2021-02-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.763 Å) | 主引用文献 | Canonical versus non-canonical transsynaptic signaling of neuroligin 3 tunes development of sociality in mice. Nat Commun, 12, 2021
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7CEG
| Crystal structure of the complex between mouse PTP delta and neuroligin-3 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform C of Receptor-type tyrosine-protein phosphatase delta, Neuroligin-3 | 著者 | Yamagata, A, Yoshida, T, Shiroshima, T, Maeda, A, Fukai, S. | 登録日 | 2020-06-23 | 公開日 | 2021-02-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.85 Å) | 主引用文献 | Canonical versus non-canonical transsynaptic signaling of neuroligin 3 tunes development of sociality in mice. Nat Commun, 12, 2021
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3VJL
| Crystal structure of human depiptidyl peptidase IV (DPP-4) in complex with a prolylthiazolidine inhibitor #2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl peptidase 4, ... | 著者 | Akahoshi, F, Kishida, H, Miyaguchi, I, Yoshida, T, Ishii, S. | 登録日 | 2011-10-24 | 公開日 | 2012-10-24 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.393 Å) | 主引用文献 | Discovery and preclinical profile of teneligliptin (3-[(2S,4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl]pyrrolidin-2-ylcarbonyl]thiazolidine): A highly potent, selective, long-lasting and orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes Bioorg.Med.Chem., 20, 2012
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3VJK
| Crystal structure of human depiptidyl peptidase IV (DPP-4) in complex with MP-513 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl peptidase 4, ... | 著者 | Akahoshi, F, Kishida, H, Miyaguchi, I, Yoshida, T, Ishii, S. | 登録日 | 2011-10-24 | 公開日 | 2012-10-24 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Discovery and preclinical profile of teneligliptin (3-[(2S,4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl]pyrrolidin-2-ylcarbonyl]thiazolidine): A highly potent, selective, long-lasting and orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes Bioorg.Med.Chem., 20, 2012
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6KLW
| Complex structure of Iota toxin enzymatic component (Ia) and binding component (Ib) pore with long stem | 分子名称: | CALCIUM ION, Iota toxin component Ia, Iota toxin component Ib | 著者 | Yoshida, T, Yamada, T, Kawamoto, A, Mitsuoka, K, Iwasaki, K, Tsuge, H. | 登録日 | 2019-07-30 | 公開日 | 2020-01-15 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Cryo-EM structures reveal translocational unfolding in the clostridial binary iota toxin complex. Nat.Struct.Mol.Biol., 27, 2020
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6KLX
| Pore structure of Iota toxin binding component (Ib) | 分子名称: | CALCIUM ION, Iota toxin component Ib | 著者 | Yoshida, T, Yamada, T, Kawamoto, A, Mitsuoka, K, Iwasaki, K, Tsuge, H. | 登録日 | 2019-07-30 | 公開日 | 2020-01-15 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Cryo-EM structures reveal translocational unfolding in the clostridial binary iota toxin complex. Nat.Struct.Mol.Biol., 27, 2020
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6KLO
| Complex structure of Iota toxin enzymatic component (Ia) and binding component (Ib) pore with short stem | 分子名称: | CALCIUM ION, Iota toxin component Ia, Iota toxin component Ib | 著者 | Yoshida, T, Yamada, T, Kawamoto, A, Mitsuoka, K, Iwasaki, K, Tsuge, H. | 登録日 | 2019-07-30 | 公開日 | 2020-01-15 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Cryo-EM structures reveal translocational unfolding in the clostridial binary iota toxin complex. Nat.Struct.Mol.Biol., 27, 2020
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3AFV
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3VJM
| Crystal structure of human depiptidyl peptidase IV (DPP-4) in complex with a prolylthiazolidine inhibitor #1 | 分子名称: | 1,3-thiazolidin-3-yl[(2S,4S)-4-{4-[2-(trifluoromethyl)quinolin-4-yl]piperazin-1-yl}pyrrolidin-2-yl]methanone, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Akahoshi, F, Kishida, H, Miyaguchi, I, Yoshida, T, Ishii, S. | 登録日 | 2011-10-24 | 公開日 | 2012-08-15 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Fused bicyclic heteroarylpiperazine-substituted l-prolylthiazolidines as highly potent DPP-4 inhibitors lacking the electrophilic nitrile group Bioorg.Med.Chem., 20, 2012
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1AYG
| SOLUTION STRUCTURE OF CYTOCHROME C-552, NMR, 20 STRUCTURES | 分子名称: | CYTOCHROME C-552, HEME C | 著者 | Hasegawa, J, Yoshida, T, Yamazaki, T, Sambongi, Y, Yu, Y, Igarashi, Y, Kodama, T, Yamazaki, K, Hakusui, H, Kyogoku, Y, Kobayashi, Y. | 登録日 | 1997-11-04 | 公開日 | 1998-11-25 | 最終更新日 | 2022-02-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of thermostable cytochrome c-552 from Hydrogenobacter thermophilus determined by 1H-NMR spectroscopy. Biochemistry, 37, 1998
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1GDH
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1O5P
| Solution Structure of holo-Neocarzinostatin | 分子名称: | NEOCARZINOSTATIN-CHROMOPHORE, Neocarzinostatin | 著者 | Takashima, H, Ishino, T, Yoshida, T, Hasuda, K, Ohkubo, T, Kobayashi, Y. | 登録日 | 2003-10-04 | 公開日 | 2003-10-14 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR Structure Investigation for Releasing Mechanism of Neocarzinostatin Chromophore from the Holoprotein J.Biol.Chem., 280, 2005
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1Q2V
| Crystal structure of the chaperonin from Thermococcus strain KS-1 (nucleotide-free form) | 分子名称: | SULFATE ION, Thermosome alpha subunit | 著者 | Shomura, Y, Yoshida, T, Iizuka, R, Yohda, M, Maruyama, T, Miki, K. | 登録日 | 2003-07-26 | 公開日 | 2004-01-27 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal Structures of the Group II Chaperonin from Thermococcus strain KS-1: Steric Hindrance by the Substituted Amino Acid, and Inter-subunit Rearrangement between Two Crystal Forms. J.Mol.Biol., 335, 2004
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1Q3R
| Crystal structure of the chaperonin from Thermococcus strain KS-1 (nucleotide-free form of single mutant) | 分子名称: | SULFATE ION, Thermosome alpha subunit | 著者 | Shomura, Y, Yoshida, T, Iizuka, R, Maruyama, T, Yohda, M, Miki, K. | 登録日 | 2003-07-31 | 公開日 | 2004-01-27 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal Structures of the Group II Chaperonin from Thermococcus strain KS-1: Steric Hindrance by the Substituted Amino Acid, and Inter-subunit Rearrangement between Two Crystal Forms. J.Mol.Biol., 335, 2004
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1Q3Q
| Crystal structure of the chaperonin from Thermococcus strain KS-1 (two-point mutant complexed with AMP-PNP) | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Thermosome alpha subunit | 著者 | Shomura, Y, Yoshida, T, Iizuka, R, Maruyama, T, Yohda, M, Miki, K. | 登録日 | 2003-07-31 | 公開日 | 2004-01-27 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structures of the Group II Chaperonin from Thermococcus strain KS-1: Steric Hindrance by the Substituted Amino Acid, and Inter-subunit Rearrangement between Two Crystal Forms. J.Mol.Biol., 335, 2004
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1Q3S
| Crystal structure of the chaperonin from Thermococcus strain KS-1 (FormIII crystal complexed with ADP) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Thermosome alpha subunit | 著者 | Shomura, Y, Yoshida, T, Iizuka, R, Maruyama, T, Yohda, M, Miki, K. | 登録日 | 2003-07-31 | 公開日 | 2004-01-27 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal Structures of the Group II Chaperonin from Thermococcus strain KS-1: Steric Hindrance by the Substituted Amino Acid, and Inter-subunit Rearrangement between Two Crystal Forms. J.Mol.Biol., 335, 2004
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