5KNE
| CryoEM Reconstruction of Hsp104 Hexamer | Descriptor: | Heat shock protein 104, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Yokom, A.L, Gates, S.N, Jackrel, M.E, Mack, K.L, Su, M, Shorter, J, Southworth, D.R. | Deposit date: | 2016-06-28 | Release date: | 2016-07-27 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (5.64 Å) | Cite: | Spiral architecture of the Hsp104 disaggregase reveals the basis for polypeptide translocation. Nat.Struct.Mol.Biol., 23, 2016
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6PAS
| Inactive State of Manduca sexta soluble guanylate cyclase | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, Soluble guanylyl cyclase alpha-1 subunit, Soluble guanylyl cyclase beta-1 subunit | Authors: | Yokom, A.L, Horst, B.G, Marletta, M.A, Hurley, J.H. | Deposit date: | 2019-06-11 | Release date: | 2019-10-23 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (5.1 Å) | Cite: | Allosteric activation of the nitric oxide receptor soluble guanylate cyclase mapped by cryo-electron microscopy. Elife, 8, 2019
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6PAT
| Active State of Manduca sexta soluble Guanylate Cyclase | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, Soluble guanylyl cyclase alpha-1 subunit, Soluble guanylyl cyclase beta-1 subunit | Authors: | Yokom, A.L, Horst, B.G, Marletta, M.A, Hurley, J.H. | Deposit date: | 2019-06-11 | Release date: | 2019-10-23 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (5.8 Å) | Cite: | Allosteric activation of the nitric oxide receptor soluble guanylate cyclase mapped by cryo-electron microscopy. Elife, 8, 2019
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5VJH
| Closed State CryoEM Reconstruction of Hsp104:ATPyS and FITC casein | Descriptor: | FITC casein, Heat shock protein 104, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | Authors: | Gates, S.N, Yokom, A.L, Lin, J.-B, Jackrel, M.E, Rizo, A.N, Kendsersky, N.M, Buell, C.E, Sweeny, E.A, Chuang, E, Torrente, M.P, Mack, K.L, Su, M, Shorter, J, Southworth, D.R. | Deposit date: | 2017-04-19 | Release date: | 2017-07-05 | Last modified: | 2017-08-02 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Ratchet-like polypeptide translocation mechanism of the AAA+ disaggregase Hsp104. Science, 357, 2017
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8DO8
| Crystal structure ATG9 HDIR in complex with the ATG13:ATG101 HORMA dimer | Descriptor: | Autophagy-related protein 101, Autophagy-related protein 13, GLYCEROL | Authors: | Buffalo, C.Z, Ren, X, Yokom, A.L, Hurley, J.H. | Deposit date: | 2022-07-12 | Release date: | 2022-11-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Structural basis for ATG9A recruitment to the ULK1 complex in mitophagy initiation. Sci Adv, 9, 2023
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5VYA
| S. cerevisiae Hsp104:casein complex, Extended Conformation | Descriptor: | Alpha-S1-casein, Heat shock protein 104, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | Authors: | Gates, S.N, Yokom, A.L, Lin, J.-B, Jackrel, M.E, Rizo, A.N, Kendsersky, N.M, Buell, C.E, Sweeny, E.A, Chuang, E, Torrente, M.P, Mack, K.L, Su, M, Shorter, J, Southworth, D.R. | Deposit date: | 2017-05-24 | Release date: | 2017-07-05 | Last modified: | 2017-08-02 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Ratchet-like polypeptide translocation mechanism of the AAA+ disaggregase Hsp104. Science, 357, 2017
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5VY9
| S. cerevisiae Hsp104:casein complex, Middle Domain Conformation | Descriptor: | Alpha-S1-casein, Heat shock protein 104, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | Authors: | Gates, S.N, Yokom, A.L, Lin, J.-B, Jackrel, M.E, Rizo, A.N, Kendsersky, N.M, Buell, C.E, Sweeny, E.A, Chuang, E, Torrente, M.P, Mack, K.L, Su, M, Shorter, J, Southworth, D.R. | Deposit date: | 2017-05-24 | Release date: | 2017-07-19 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (6.7 Å) | Cite: | Ratchet-like polypeptide translocation mechanism of the AAA+ disaggregase Hsp104. Science, 357, 2017
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5VY8
| S. cerevisiae Hsp104-ADP complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Heat shock protein 104 | Authors: | Gates, S.N, Yokom, A.L, Lin, J.-B, Jackrel, M.E, Rizo, A.N, Kendsersky, N.M, Buell, C.E, Sweeny, E.A, Chuang, E, Torrente, M.P, Mack, K.L, Su, M, Shorter, J, Southworth, D.R. | Deposit date: | 2017-05-24 | Release date: | 2017-07-05 | Last modified: | 2018-08-15 | Method: | ELECTRON MICROSCOPY (5.6 Å) | Cite: | Ratchet-like polypeptide translocation mechanism of the AAA+ disaggregase Hsp104. Science, 357, 2017
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6VME
| Human ESCRT-I heterotetramer headpiece | Descriptor: | Multivesicular body subunit 12A, Tumor susceptibility gene 101 protein, Vacuolar protein sorting-associated protein 28 homolog, ... | Authors: | Flower, T.G, Hurley, J.H, Tjahjono, N. | Deposit date: | 2020-01-27 | Release date: | 2020-05-20 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | A helical assembly of human ESCRT-I scaffolds reverse-topology membrane scission. Nat.Struct.Mol.Biol., 27, 2020
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6NZD
| Cryo-EM Structure of the Lysosomal Folliculin Complex (FLCN-FNIP2-RagA-RagC-Ragulator) | Descriptor: | 9-{5-O-[(S)-hydroxy{[(R)-hydroxy(thiophosphonooxy)phosphoryl]oxy}phosphoryl]-alpha-L-arabinofuranosyl}-3,9-dihydro-1H-purine-2,6-dione, Folliculin, Folliculin-interacting protein 2, ... | Authors: | Fromm, S.A, Young, L.N, Hurley, J.H. | Deposit date: | 2019-02-13 | Release date: | 2019-11-06 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex. Science, 366, 2019
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8DHB
| Active FLCN GAP complex | Descriptor: | BERYLLIUM TRIFLUORIDE ION, Folliculin, Folliculin-interacting protein 2, ... | Authors: | Jansen, R.M, Hurley, J.H. | Deposit date: | 2022-06-25 | Release date: | 2022-09-28 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3.53 Å) | Cite: | Structural basis for FLCN RagC GAP activation in MiT-TFE substrate-selective mTORC1 regulation. Sci Adv, 8, 2022
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