1S1G
| Crystal Structure of Kv4.3 T1 Domain | 分子名称: | Potassium voltage-gated channel subfamily D member 3, ZINC ION | 著者 | Scannevin, R.H, Wang, K.W, Jow, F, Megules, J, Kopsco, D.C, Edris, W, Carroll, K.C, Lu, Q, Xu, W.X, Xu, Z.B, Katz, A.H, Olland, S, Lin, L, Taylor, M, Stahl, M, Malakian, K, Somers, W, Mosyak, L, Bowlby, M.R, Chanda, P, Rhodes, K.J. | 登録日 | 2004-01-06 | 公開日 | 2004-03-23 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Two N-terminal domains of Kv4 K(+) channels regulate binding to and modulation by KChIP1. Neuron, 41, 2004
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1GLU
| CRYSTALLOGRAPHIC ANALYSIS OF THE INTERACTION OF THE GLUCOCORTICOID RECEPTOR WITH DNA | 分子名称: | DNA (5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*TP*CP*GP*AP*TP*GP*TP*TP*C P*TP*G)-3'), PROTEIN (GLUCOCORTICOID RECEPTOR), ZINC ION | 著者 | Luisi, B.F, Xu, W.X, Otwinowski, Z, Freedman, L.P, Yamamoto, K.R, Sigler, P.B. | 登録日 | 1992-08-30 | 公開日 | 1994-01-31 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA. Nature, 352, 1991
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2AZR
| Crystal structure of PTP1B with Bicyclic Thiophene inhibitor | 分子名称: | 3-(CARBOXYMETHOXY)THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID, Tyrosine-protein phosphatase, non-receptor type 1 | 著者 | Moretto, A.F, Kirincich, S.J, Xu, W.X, Smith, M.J, Wan, Z.K, Wilson, D.P, Follows, B.C, Binnun, E, Joseph-McCarthy, D, Foreman, K, Erbe, D.V, Zhang, Y.L, Tam, S.K, Tam, S.Y, Lee, J. | 登録日 | 2005-09-12 | 公開日 | 2005-12-06 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Bicyclic and tricyclic thiophenes as protein tyrosine phosphatase 1B inhibitors. Bioorg.Med.Chem., 14, 2006
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2B07
| Crystal structure of PTP1B with Tricyclic Thiophene inhibitor. | 分子名称: | 6-{[1-(BENZYLSULFONYL)PIPERIDIN-4-YL]AMINO}-3-(CARBOXYMETHOXY)THIENO[3,2-B][1]BENZOTHIOPHENE-2-CARBOXYLIC ACID, Tyrosine-protein phosphatase, non-receptor type 1 | 著者 | Moretto, A.F, Kirincich, S.J, Xu, W.X, Smith, M.J, Wan, Z.K, Wilson, D.P, Follows, B.C, Binnun, E, Joseph-McCarthy, D, Foreman, K, Erbe, D.V, Zhang, Y.L, Tam, S.K, Tam, S.Y, Lee, J. | 登録日 | 2005-09-13 | 公開日 | 2005-12-06 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Bicyclic and tricyclic thiophenes as protein tyrosine phosphatase 1B inhibitors. Bioorg.Med.Chem., 14, 2006
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1R4R
| Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA | 分子名称: | 5'-D(*CP*TP*GP*AP*GP*AP*AP*CP*AP*TP*CP*AP*TP*GP*TP*TP*CP*TP*G)-3', 5'-D(*TP*CP*AP*GP*AP*AP*CP*AP*TP*GP*AP*TP*GP*TP*TP*CP*TP*CP*A)-3', Glucocorticoid receptor, ... | 著者 | Luisi, B.F, Xu, W.X, Otwinowski, Z, Freedman, L.P, Yamamoto, K.R, Sigler, P.B. | 登録日 | 2003-10-07 | 公開日 | 2003-10-28 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystallographic Analysis of the Interaction of the Glucocorticoid Receptor with DNA Nature, 352, 1991
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1R4O
| Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA | 分子名称: | 5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*TP*CP*GP*AP*TP*GP*TP*TP*CP*TP*G)-3', Glucocorticoid receptor, ZINC ION | 著者 | Luisi, B.F, Xu, W.X, Otwinowski, Z, Freedman, L.P, Yamamoto, K.R, Sigler, P.B. | 登録日 | 2003-10-07 | 公開日 | 2003-10-21 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystallographic Analysis of the Interaction of The Glucocorticoid Receptor with DNA Nature, 352, 1991
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2QBR
| Crystal structure of ptp1b-inhibitor complex | 分子名称: | 5-[3-(BENZYLAMINO)PHENYL]-4-BROMO-3-(CARBOXYMETHOXY)THIOPHENE-2-CARBOXYLIC ACID, Tyrosine-protein phosphatase non-receptor type 1 | 著者 | Xu, W. | 登録日 | 2007-06-18 | 公開日 | 2008-03-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure-based optimization of protein tyrosine phosphatase 1B inhibitors: from the active site to the second phosphotyrosine binding site. J.Med.Chem., 50, 2007
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2QBQ
| Crystal structure of ptp1b-inhibitor complex | 分子名称: | 4-BROMO-3-(CARBOXYMETHOXY)-5-{3-[(3,3,5,5-TETRAMETHYLCYCLOHEXYL)AMINO]PHENYL}THIOPHENE-2-CARBOXYLIC ACID, Tyrosine-protein phosphatase non-receptor type 1 | 著者 | Xu, W. | 登録日 | 2007-06-18 | 公開日 | 2008-03-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure-based optimization of protein tyrosine phosphatase 1B inhibitors: from the active site to the second phosphotyrosine binding site. J.Med.Chem., 50, 2007
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2QBP
| Crystal structure of ptp1b-inhibitor complex | 分子名称: | 5-(3-{[1-(BENZYLSULFONYL)PIPERIDIN-4-YL]AMINO}PHENYL)-4-BROMO-3-(CARBOXYMETHOXY)THIOPHENE-2-CARBOXYLIC ACID, Tyrosine-protein phosphatase non-receptor type 1 | 著者 | Xu, W. | 登録日 | 2007-06-18 | 公開日 | 2008-03-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure-based optimization of protein tyrosine phosphatase 1B inhibitors: from the active site to the second phosphotyrosine binding site. J.Med.Chem., 50, 2007
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2QBS
| Crystal structure of ptp1b-inhibitor complex | 分子名称: | 4-BROMO-3-(CARBOXYMETHOXY)-5-[3-(CYCLOHEXYLAMINO)PHENYL]THIOPHENE-2-CARBOXYLIC ACID, Tyrosine-protein phosphatase non-receptor type 1 | 著者 | Xu, W. | 登録日 | 2007-06-18 | 公開日 | 2008-03-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure-based optimization of protein tyrosine phosphatase 1B inhibitors: from the active site to the second phosphotyrosine binding site. J.Med.Chem., 50, 2007
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1GDC
| REFINED SOLUTION STRUCTURE OF THE GLUCOCORTICOID RECEPTOR DNA-BINDING DOMAIN | 分子名称: | GLUCOCORTICOID RECEPTOR, ZINC ION | 著者 | Baumann, H, Paulsen, K, Kovacs, H, Berglund, H, Wright, A.P.H, Gustafsson, J.-A, Hard, T. | 登録日 | 1994-03-15 | 公開日 | 1994-06-22 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | Refined solution structure of the glucocorticoid receptor DNA-binding domain. Biochemistry, 32, 1993
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2GDA
| REFINED SOLUTION STRUCTURE OF THE GLUCOCORTICOID RECEPTOR DNA-BINDING DOMAIN | 分子名称: | GLUCOCORTICOID RECEPTOR, ZINC ION | 著者 | Baumann, H, Paulsen, K, Kovacs, H, Berglund, H, Wright, A.P.H, Gustafsson, J.-A, Hard, T. | 登録日 | 1994-03-15 | 公開日 | 1994-06-22 | 最終更新日 | 2022-03-09 | 実験手法 | SOLUTION NMR | 主引用文献 | Refined solution structure of the glucocorticoid receptor DNA-binding domain. Biochemistry, 32, 1993
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1RGD
| STRUCTURE REFINEMENT OF THE GLUCOCORTICOID RECEPTOR-DNA BINDING DOMAIN FROM NMR DATA BY RELAXATION MATRIX CALCULATIONS | 分子名称: | GLUCOCORTICOID RECEPTOR, ZINC ION | 著者 | Van Tilborg, M.A.A, Bonvin, A.M.J.J, Hard, K, Davis, A, Maler, B, Boelens, R, Yamamoto, K.R, Kaptein, R. | 登録日 | 1995-01-06 | 公開日 | 1995-02-14 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure refinement of the glucocorticoid receptor-DNA binding domain from NMR data by relaxation matrix calculations. J.Mol.Biol., 247, 1995
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7XP5
| Cryo-EM structure of a class T GPCR in ligand-free state | 分子名称: | Endoglucanase H,Taste receptor type 2 member 46,Bitter taste receptor T2R46, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Liu, Z.J, Hua, T, Xu, W.X, Wu, L.J. | 登録日 | 2022-05-03 | 公開日 | 2022-10-12 | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | 主引用文献 | Structural basis for strychnine activation of human bitter taste receptor TAS2R46. Science, 377, 2022
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7XP6
| Cryo-EM structure of a class T GPCR in active state | 分子名称: | Endoglucanase H,Taste receptor type 2 member 46,Endoglucanase H,Taste receptor type 2 member 46,Bitter taste receptor T2R46, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Liu, Z.J, Hua, T, Xu, W.X, Wu, L.J. | 登録日 | 2022-05-03 | 公開日 | 2022-10-12 | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | 主引用文献 | Structural basis for strychnine activation of human bitter taste receptor TAS2R46. Science, 377, 2022
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7XP4
| Cryo-EM structure of a class T GPCR in apo state | 分子名称: | Endoglucanase H,Taste receptor type 2 member 46,Endoglucanase H,Taste receptor type 2 member 46,Bitter taste receptor T2R46, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Liu, Z.J, Hua, T, Xu, W.X, Wu, L.J. | 登録日 | 2022-05-03 | 公開日 | 2022-10-12 | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | 主引用文献 | Structural basis for strychnine activation of human bitter taste receptor TAS2R46. Science, 377, 2022
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