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1G10
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TOLUENE-4-MONOOXYGENASE CATALYTIC EFFECTOR PROTEIN NMR STRUCTURE
分子名称: TOLUENE-4-MONOOXYGENASE CATALYTIC EFFECTOR
著者Hemmi, H, Studts, J.M, Chae, Y.K, Song, J, Markley, J.L, Fox, B.G.
登録日2000-10-10
公開日2001-05-09
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure of the toluene 4-monooxygenase effector protein (T4moD).
Biochemistry, 40, 2001
6IIU
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Crystal structure of the human thromboxane A2 receptor bound to ramatroban
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3-[(3R)-3-[(4-fluorophenyl)sulfonylamino]-1,2,3,4-tetrahydrocarbazol-9-yl]propanoic acid, CHOLESTEROL, ...
著者Fan, H, Zhao, Q, Wu, B.
登録日2018-10-07
公開日2018-12-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for ligand recognition of the human thromboxane A2receptor.
Nat. Chem. Biol., 15, 2019
6IIV
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Crystal structure of the human thromboxane A2 receptor bound to daltroban
分子名称: 2-[4-[2-[(4-chlorophenyl)sulfonylamino]ethyl]phenyl]ethanoic acid, CHOLESTEROL, GLYCEROL, ...
著者Fan, H, Zhao, Q, Wu, B.
登録日2018-10-07
公開日2018-12-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for ligand recognition of the human thromboxane A2receptor.
Nat. Chem. Biol., 15, 2019
6K10
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Non substrate bound state of Staphylococcus Aureus AldH
分子名称: 1,2-ETHANEDIOL, Aldehyde dehydrogenase
著者Zhang, Z, Tao, X.
登録日2019-05-08
公開日2020-05-20
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.78962183 Å)
主引用文献Structural Insight into the Substrate Gating Mechanism by Staphylococcus aureus Aldehyde Dehydrogenase
CCS Chemistry, 2, 2020
6K0Z
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Substrate bound state of Staphylococcus Aureus AldH
分子名称: 1,2-ETHANEDIOL, Aldehyde dehydrogenase, GLYCEROL
著者Zhang, Z, Tao, X.
登録日2019-05-08
公開日2020-05-20
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.4967258 Å)
主引用文献Structural Insight into the Substrate Gating Mechanism by Staphylococcus aureus Aldehyde Dehydrogenase
CCS Chemistry, 2, 2020
8H03
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Major polymorph in alpha-synuclein fibril seeded by cerebrospinal fluid from a preclinical Parkinson's disease patient
分子名称: Alpha-synuclein
著者Fan, Y, Sun, Y.P, Wang, J, Liu, C.
登録日2022-09-28
公開日2022-11-30
最終更新日2023-01-25
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
8H04
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Major polymorph in alpha-synuclein fibril seeded by cerebrospinal fluid from a postmortal Parkinson's disease patient
分子名称: Alpha-synuclein
著者Fan, Y, Sun, Y.P, Wang, J, Liu, C.
登録日2022-09-28
公開日2022-11-30
最終更新日2023-01-25
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
8H05
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Minor polymorph in alpha-synuclein fibril seeded by cerebrospinal fluid from a postmortal Parkinson's disease patient
分子名称: Alpha-synuclein
著者Fan, Y, Sun, Y.P, Wang, J, Liu, C.
登録日2022-09-28
公開日2022-11-30
最終更新日2023-01-25
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
1SJG
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Solution Structure of T4moC, the Rieske Ferredoxin Component of the Toluene 4-Monooxygenase Complex
分子名称: FE2/S2 (INORGANIC) CLUSTER, Toluene-4-monooxygenase system protein C
著者Skjeldal, L, Peterson, F.C, Doreleijers, J.F, Moe, L.A, Pikus, J.D, Volkman, B.F, Westler, W.M, Markley, J.L, Fox, B.G.
登録日2004-03-03
公開日2004-09-07
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of T4moC, the Rieske ferredoxin component of the toluene 4-monooxygenase complex
J.Biol.Inorg.Chem., 9, 2004
5Y28
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Crystal structure of H. pylori HtrA with PDZ2 deletion
分子名称: 1,2-ETHANEDIOL, Periplasmic serine endoprotease DegP-like, UNK-UNK-UNK-UNK
著者Zhang, Z, Huang, Q, Tao, X.
登録日2017-07-24
公開日2018-08-15
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.08606815 Å)
主引用文献The unique trimeric assembly of the virulence factor HtrA fromHelicobacter pylorioccurs via N-terminal domain swapping.
J.Biol.Chem., 294, 2019
5Y2D
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Crystal structure of H. pylori HtrA
分子名称: Periplasmic serine endoprotease DegP-like, UNK-UNK-K-UNK-UNK-UNK-UNK-UNK-UNK-UNK, UNK-UNK-UNK, ...
著者Zhang, Z, Huang, Q, Tao, X.
登録日2017-07-25
公開日2018-08-15
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.70009851 Å)
主引用文献The unique trimeric assembly of the virulence factor HtrA fromHelicobacter pylorioccurs via N-terminal domain swapping.
J.Biol.Chem., 294, 2019
7E0F
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CryoEM structure of G51D alpha-synuclein amyloid fibril
分子名称: Alpha-synuclein
著者Sun, Y.P, Long, H.F, Xia, W.C, Liu, C.
登録日2021-01-27
公開日2021-10-06
最終更新日2022-02-23
実験手法ELECTRON MICROSCOPY (3.02 Å)
主引用文献The hereditary mutation G51D unlocks a distinct fibril strain transmissible to wild-type alpha-synuclein.
Nat Commun, 12, 2021
7F29
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Cryo-EM structure of the fibril formed by disaccharide-modified amyloid-beta(1-42)
分子名称: ACETIC ACID, Amyloid-beta A4 protein, beta-D-galactopyranose-(1-3)-2-amino-2-deoxy-alpha-D-galactopyranose
著者Xia, W.C, Sun, Y.P, Liu, C.
登録日2021-06-10
公開日2022-07-13
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献O-Glycosylation Induces Amyloid-beta To Form New Fibril Polymorphs Vulnerable for Degradation
J.Am.Chem.Soc., 143, 2021
7VQQ
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Cryo-EM structure of amyloid fibril formed by FUS low complexity domain
分子名称: fusion protein of mCerulean and FUS LCD
著者Sun, Y.P, Xia, W.C, Liu, C.
登録日2021-10-20
公開日2021-12-22
最終更新日2022-02-23
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Molecular structure of an amyloid fibril formed by FUS low-complexity domain.
Iscience, 25, 2022
7YK2
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Cryo-EM structure of Apo-alpha-syn fibril
分子名称: Alpha-synuclein
著者Xu, Q.H, Xia, W.C, Tao, Y.Q, Liu, C.
登録日2022-07-21
公開日2023-03-22
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Conformational Dynamics of an alpha-Synuclein Fibril upon Receptor Binding Revealed by Insensitive Nuclei Enhanced by Polarization Transfer-Based Solid-State Nuclear Magnetic Resonance and Cryo-Electron Microscopy.
J.Am.Chem.Soc., 145, 2023
7YK8
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Cryo-EM structure of dLAG3-alpha-syn fibril
分子名称: Alpha-synuclein
著者Xu, Q.H, Xia, W.C, Tao, Y.Q, Liu, C.
登録日2022-07-22
公開日2023-03-22
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Conformational Dynamics of an alpha-Synuclein Fibril upon Receptor Binding Revealed by Insensitive Nuclei Enhanced by Polarization Transfer-Based Solid-State Nuclear Magnetic Resonance and Cryo-Electron Microscopy.
J.Am.Chem.Soc., 145, 2023
7V47
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Type 1A alpha-synuclein fibril seeded by cerebrospinal fluid from a preclinical Parkinson's disease patient
分子名称: Alpha-synuclein
著者Fan, Y, Sun, Y.P, Wang, J, Liu, C.
登録日2021-08-12
公開日2022-08-17
最終更新日2023-01-25
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7V49
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Type 4 alpha-synuclein fibril seeded by cerebrospinal fluid from a postmortal Parkinson's disease patient
分子名称: Alpha-synuclein
著者Fan, Y, Sun, Y.P, Wang, J, Liu, C.
登録日2021-08-12
公開日2022-08-17
最終更新日2023-01-25
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7V48
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Type 1D alpha-synuclein fibril seeded by cerebrospinal fluid from a postmortal Parkinson's disease patient
分子名称: Alpha-synuclein
著者Fan, Y, Sun, Y.P, Wang, J, Liu, C.
登録日2021-08-12
公開日2022-08-17
最終更新日2023-01-25
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7XO2
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Minor polymorph in alpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-4) Parkinson's disease patient
分子名称: Alpha-synuclein
著者Fan, Y, Sun, Y.P, Wang, J, Liu, C.
登録日2022-04-30
公開日2022-11-30
最終更新日2023-01-25
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7XO3
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Type 1C alpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-4) Parkinson's disease patient
分子名称: Alpha-synuclein
著者Fan, Y, Sun, Y.P, Wang, J, Liu, C.
登録日2022-04-30
公開日2022-11-30
最終更新日2023-01-25
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7XO0
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Minor polymorph inalpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-1) Parkinson's disease patient
分子名称: Alpha-synuclein
著者Fan, Y, Sun, Y.P, Wang, J, Liu, C.
登録日2022-04-30
公開日2022-11-30
最終更新日2023-01-25
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7XO1
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Major polymorph in alpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-1) Parkinson's disease patient
分子名称: Alpha-synuclein
著者Fan, Y, Sun, Y.P, Wang, J, Liu, C.
登録日2022-04-30
公開日2022-11-30
最終更新日2023-01-25
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7YPG
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Cryo-EM structure of amyloid fibril formed by tau (297-391)
分子名称: Isoform Tau-E of Microtubule-associated protein tau
著者Zhang, S.Q, Li, X, Liu, C.
登録日2022-08-03
公開日2022-12-14
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Subtle change of fibrillation condition leads to substantial alteration of recombinant Tau fibril structure.
Iscience, 25, 2022
7YMN
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Cryo-EM structure of in vitro PHF fibril
分子名称: Isoform Tau-D of Microtubule-associated protein tau
著者Li, X, Liu, C.
登録日2022-07-28
公開日2022-12-14
最終更新日2022-12-28
実験手法ELECTRON MICROSCOPY (3.46 Å)
主引用文献Subtle change of fibrillation condition leads to substantial alteration of recombinant Tau fibril structure.
Iscience, 25, 2022

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