6IIV

Crystal structure of the human thromboxane A2 receptor bound to daltroban

Summary for 6IIV

Entry DOI	10.2210/pdb6iiv/pdb
Descriptor	Soluble cytochrome b562,Thromboxane A2 receptor,Rubredoxin,Thromboxane A2 receptor, 2-[4-[2-[(4-chlorophenyl)sulfonylamino]ethyl]phenyl]ethanoic acid, ZINC ION, ... (5 entities in total)
Functional Keywords	gpcr, complex, antagonist, signaling protein
Biological source	Escherichia coli More
Total number of polymer chains	1
Total formula weight	54140.22
Authors	Fan, H.,Zhao, Q.,Wu, B. (deposition date: 2018-10-07, release date: 2018-12-19, Last modification date: 2023-11-22)
Primary citation	Fan, H.,Chen, S.,Yuan, X.,Han, S.,Zhang, H.,Xia, W.,Xu, Y.,Zhao, Q.,Wu, B. Structural basis for ligand recognition of the human thromboxane A2receptor. Nat. Chem. Biol., 15:27-33, 2019 Cited by PubMed: 30510189 DOI: 10.1038/s41589-018-0170-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation