7V9A
| biogenesis module of human telomerase holoenzyme | Descriptor: | H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 2, H/ACA ribonucleoprotein complex subunit 3, ... | Authors: | Wan, F, Ding, Y, Yang, L, Wu, Z, Wu, J, Lei, M. | Deposit date: | 2021-08-24 | Release date: | 2022-03-30 | Method: | ELECTRON MICROSCOPY (3.94 Å) | Cite: | Zipper head mechanism of telomere synthesis by human telomerase. Cell Res., 31, 2021
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2KMK
| Gfi-1 Zinc Fingers 3-5 complexed with DNA | Descriptor: | DNA (5'-D(*CP*AP*TP*AP*AP*AP*TP*CP*AP*CP*TP*GP*CP*CP*TP*A)-3'), DNA (5'-D(*TP*AP*GP*GP*CP*AP*GP*TP*GP*AP*TP*TP*TP*AP*TP*G)-3'), ZINC ION, ... | Authors: | Lee, S, Wu, Z. | Deposit date: | 2009-07-30 | Release date: | 2010-03-02 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Solution structure of Gfi-1 zinc domain bound to consensus DNA. J.Mol.Biol., 397, 2010
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2KHZ
| Solution Structure of RCL | Descriptor: | c-Myc-responsive protein Rcl | Authors: | Doddapaneni, K, Mahler, B, Yuan, C, Wu, Z. | Deposit date: | 2009-04-15 | Release date: | 2009-10-13 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Solution structure of RCL, a novel 2'-deoxyribonucleoside 5'-monophosphate N-glycosidase J.Mol.Biol., 394, 2009
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7CUI
| Crystal structure of fission yeast Pot1 and Tpz1 | Descriptor: | Protection of telomeres protein 1, Protection of telomeres protein tpz1, SULFATE ION | Authors: | Sun, H, Wu, Z, Wu, J, Lei, M. | Deposit date: | 2020-08-23 | Release date: | 2021-08-25 | Last modified: | 2022-09-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural insights into Pot1-ssDNA, Pot1-Tpz1 and Tpz1-Ccq1 Interactions within fission yeast shelterin complex. Plos Genet., 18, 2022
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7CUJ
| Crystal structure of fission yeast Ccq1 and Tpz1 | Descriptor: | Coiled-coil quantitatively-enriched protein 1, Protection of telomeres protein tpz1 | Authors: | Sun, H, Wu, Z, Wu, J, Lei, M. | Deposit date: | 2020-08-23 | Release date: | 2021-08-25 | Last modified: | 2022-09-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural insights into Pot1-ssDNA, Pot1-Tpz1 and Tpz1-Ccq1 Interactions within fission yeast shelterin complex. Plos Genet., 18, 2022
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7CUH
| Crystal structure of fission yeast Pot1 and ssDNA | Descriptor: | Protection of telomeres protein 1, Telomere single-strand DNA | Authors: | Sun, H, Wu, Z, Wu, J, Lei, M. | Deposit date: | 2020-08-23 | Release date: | 2021-08-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural insights into Pot1-ssDNA, Pot1-Tpz1 and Tpz1-Ccq1 Interactions within fission yeast shelterin complex. Plos Genet., 18, 2022
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3IR1
| Crystal Structure of Lipoprotein GNA1946 from Neisseria meningitidis | Descriptor: | METHIONINE, Outer membrane lipoprotein GNA1946, SULFATE ION | Authors: | Yang, X, Wu, Z, Wang, X, Shen, Y. | Deposit date: | 2009-08-21 | Release date: | 2009-10-13 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal structure of lipoprotein GNA1946 from Neisseria meningitidis J.Struct.Biol., 168, 2009
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5VTO
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3QZR
| Human enterovirus 71 3C protease mutant E71A in complex with rupintrivir | Descriptor: | 1,2-ETHANEDIOL, 3C protein, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER | Authors: | Wang, J, Fan, T, Yao, X, Wu, Z, Guo, L, Lei, X, Wang, J, Wang, M, Jin, Q, Cui, S. | Deposit date: | 2011-03-07 | Release date: | 2011-08-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.039 Å) | Cite: | Crystal Structures of Enterovirus 71 3C Protease Complexed with Rupintrivir Reveal the Roles of Catalytically Important Residues. J.Virol., 85, 2011
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3QZQ
| Human enterovirus 71 3C protease mutant E71D in complex with rupintrivir | Descriptor: | 3C protein, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER | Authors: | Wang, J, Fan, T, Yao, X, Wu, Z, Guo, L, Lei, X, Wang, J, Wang, M, Jin, Q, Cui, S. | Deposit date: | 2011-03-07 | Release date: | 2011-08-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.7001 Å) | Cite: | Crystal Structures of Enterovirus 71 3C Protease Complexed with Rupintrivir Reveal the Roles of Catalytically Important Residues. J.Virol., 85, 2011
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3R0F
| Human enterovirus 71 3C protease mutant H133G in complex with rupintrivir | Descriptor: | 1,2-ETHANEDIOL, 3C protein, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER | Authors: | Wang, J, Fan, T, Yao, X, Wu, Z, Guo, L, Lei, X, Wang, J, Wang, M, Jin, Q, Cui, S. | Deposit date: | 2011-03-08 | Release date: | 2011-08-10 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.3083 Å) | Cite: | Crystal Structures of Enterovirus 71 3C Protease Complexed with Rupintrivir Reveal the Roles of Catalytically Important Residues. J.Virol., 85, 2011
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2M3C
| Solution Structure of gammaM7-Crystallin | Descriptor: | Crystallin, gamma M7 | Authors: | Mahler, B, Wu, Z. | Deposit date: | 2013-01-16 | Release date: | 2013-08-28 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structure and Dynamics of the Fish Eye Lens Protein, gamma M7-Crystallin. Biochemistry, 52, 2013
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2OZ7
| Crystal structure of the human androgen receptor T877A mutant ligand-binding domain with cyproterone acetate | Descriptor: | Androgen receptor, CYPROTERONE ACETATE | Authors: | Bohl, C.E, Wu, Z, Miller, D.D, Bell, C.E, Dalton, J.T. | Deposit date: | 2007-02-25 | Release date: | 2007-03-27 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the T877A human androgen receptor ligand-binding domain complexed to cyproterone acetate provides insight for ligand-induced conformational changes and structure-based drug design. J.Biol.Chem., 282, 2007
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7EG7
| TFIID-based core PIC on SCP promoter | Descriptor: | DNA (79-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | Authors: | Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y. | Deposit date: | 2021-03-24 | Release date: | 2021-05-05 | Last modified: | 2021-05-19 | Method: | ELECTRON MICROSCOPY (6.2 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7EDX
| p53-bound TFIID-based core PIC on HDM2 promoter | Descriptor: | DNA (84-mer), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | Authors: | Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y. | Deposit date: | 2021-03-17 | Release date: | 2021-05-05 | Last modified: | 2021-05-19 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7EGF
| TFIID lobe A subcomplex | Descriptor: | TATA-box-binding protein, Transcription initiation factor TFIID subunit 10, Transcription initiation factor TFIID subunit 11, ... | Authors: | Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y. | Deposit date: | 2021-03-24 | Release date: | 2021-05-05 | Method: | ELECTRON MICROSCOPY (3.16 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 2021
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7EGA
| TFIID-based intermediate PIC on PUMA promoter | Descriptor: | DNA (85-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | Authors: | Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y. | Deposit date: | 2021-03-24 | Release date: | 2021-05-05 | Last modified: | 2021-05-19 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7EG9
| TFIID-based intermediate PIC on SCP promoter | Descriptor: | DNA (79-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | Authors: | Chen, X, Qi, Y, Wang, X, Wu, Z, Li, J, Xu, Y. | Deposit date: | 2021-03-24 | Release date: | 2021-05-05 | Last modified: | 2021-05-19 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7EGG
| TFIID lobe B subcomplex | Descriptor: | Transcription initiation factor TFIID subunit 10, Transcription initiation factor TFIID subunit 12, Transcription initiation factor TFIID subunit 4, ... | Authors: | Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y. | Deposit date: | 2021-03-24 | Release date: | 2021-05-05 | Last modified: | 2021-05-19 | Method: | ELECTRON MICROSCOPY (2.77 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7EG8
| TFIID-based core PIC on PUMA promoter | Descriptor: | DNA (85-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | Authors: | Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y. | Deposit date: | 2021-03-24 | Release date: | 2021-05-05 | Last modified: | 2021-05-19 | Method: | ELECTRON MICROSCOPY (7.4 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7EGB
| TFIID-based holo PIC on SCP promoter | Descriptor: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | Authors: | Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y. | Deposit date: | 2021-03-24 | Release date: | 2021-05-05 | Last modified: | 2023-07-26 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7EGH
| TFIID lobe C subcomplex | Descriptor: | DNA (45-MER), Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 2, ... | Authors: | Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y. | Deposit date: | 2021-03-24 | Release date: | 2021-05-12 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7EGI
| TFIID in rearranged conformation | Descriptor: | TATA-box-binding protein, Transcription initiation factor IIA subunit 1, Transcription initiation factor IIA subunit 2, ... | Authors: | Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y. | Deposit date: | 2021-03-24 | Release date: | 2021-05-12 | Method: | ELECTRON MICROSCOPY (9.82 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7EGD
| SCP promoter-bound TFIID-TFIIA in initial TBP-loading state | Descriptor: | DNA (72-MER), TATA-box-binding protein, Transcription initiation factor IIA subunit 1, ... | Authors: | Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y. | Deposit date: | 2021-03-24 | Release date: | 2021-05-12 | Method: | ELECTRON MICROSCOPY (6.75 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7EGJ
| SCP promoter-bound TFIID-TFIIA in post TBP-loading state | Descriptor: | DNA (74-MER), TATA-box-binding protein, Transcription initiation factor IIA subunit 1, ... | Authors: | Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y. | Deposit date: | 2021-03-24 | Release date: | 2021-05-12 | Method: | ELECTRON MICROSCOPY (8.64 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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