Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

3QZR

Human enterovirus 71 3C protease mutant E71A in complex with rupintrivir

Summary for 3QZR
Entry DOI10.2210/pdb3qzr/pdb
Related3OSY
Descriptor3C protein, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywordschymotrypsin-fold, beta-ribbon, hydrolysis, nucleus, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHuman enterovirus 71
Total number of polymer chains2
Total formula weight42414.63
Authors
Wang, J.,Fan, T.,Yao, X.,Wu, Z.,Guo, L.,Lei, X.,Wang, J.,Wang, M.,Jin, Q.,Cui, S. (deposition date: 2011-03-07, release date: 2011-08-10, Last modification date: 2024-02-21)
Primary citationWang, J.,Fan, T.,Yao, X.,Wu, Z.,Guo, L.,Lei, X.,Wang, J.,Wang, M.,Jin, Q.,Cui, S.
Crystal Structures of Enterovirus 71 3C Protease Complexed with Rupintrivir Reveal the Roles of Catalytically Important Residues.
J.Virol., 85:10021-10030, 2011
Cited by
PubMed: 21813612
DOI: 10.1128/JVI.05107-11
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.039 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon