5M2A
 
 | | Structure of a bacterial light-regulated adenylyl cylcase | | 分子名称: | Beta subunit of photoactivated adenylyl cyclase, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ... | | 著者 | Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. | | 登録日 | 2016-10-12 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase.
J. Mol. Biol., 429, 2017
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5M27
 | | Structure of a bacterial light-regulated adenylyl cylcase | | 分子名称: | Beta subunit of photoactivated adenylyl cyclase, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. | | 登録日 | 2016-10-12 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase.
J. Mol. Biol., 429, 2017
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5MBD
 | | Structure of a bacterial light-regulated adenylyl cylcase | | 分子名称: | Beta subunit of photoactivated adenylyl cyclase, CHLORIDE ION, FLAVIN MONONUCLEOTIDE | | 著者 | Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. | | 登録日 | 2016-11-08 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase.
J. Mol. Biol., 429, 2017
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5MBJ
 | | Structure of a bacterial light-regulated adenylyl cyclase | | 分子名称: | Beta subunit of photoactivated adenylyl cyclase, FLAVIN MONONUCLEOTIDE | | 著者 | Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. | | 登録日 | 2016-11-08 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase.
J. Mol. Biol., 429, 2017
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5MBE
 | | Structure of a bacterial light-regulated adenylyl cylcase | | 分子名称: | Beta subunit of photoactivated adenylyl cyclase, FLAVIN MONONUCLEOTIDE | | 著者 | Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. | | 登録日 | 2016-11-08 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase.
J. Mol. Biol., 429, 2017
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5MBH
 | | Structure of a bacterial light-regulated adenylyl cyclase | | 分子名称: | Beta subunit of photoactivated adenylyl cyclase, FLAVIN MONONUCLEOTIDE | | 著者 | Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. | | 登録日 | 2016-11-08 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase.
J. Mol. Biol., 429, 2017
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5MBG
 | | Structure of a bacterial light-regulated adenylyl cyclase | | 分子名称: | Beta subunit of photoactivated adenylyl cyclase, IODIDE ION | | 著者 | Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. | | 登録日 | 2016-11-08 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase.
J. Mol. Biol., 429, 2017
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5MBC
 | | Structure of a bacterial light-regulated adenylyl cylcase | | 分子名称: | Beta subunit of photoactivated adenylyl cyclase, CHLORIDE ION, FLAVIN MONONUCLEOTIDE | | 著者 | Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. | | 登録日 | 2016-11-08 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase.
J. Mol. Biol., 429, 2017
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5MBB
 | | Structure of a bacterial light-regulated adenylyl cylcase | | 分子名称: | Beta subunit of photoactivated adenylyl cyclase, FLAVIN MONONUCLEOTIDE | | 著者 | Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. | | 登録日 | 2016-11-08 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase.
J. Mol. Biol., 429, 2017
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5MBK
 | | Structure of a bacterial light-regulated adenylyl cylcase | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Beta subunit of photoactivated adenylyl cyclase, MAGNESIUM ION | | 著者 | Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. | | 登録日 | 2016-11-08 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase.
J. Mol. Biol., 429, 2017
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6EO5
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6EO4
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6ET7
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6FHT
 | | Crystal structure of an artificial phytochrome regulated adenylate/guanylate cyclase in its dark adapted Pr form | | 分子名称: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, Bacteriophytochrome,Adenylate cyclase, DODECAETHYLENE GLYCOL, ... | | 著者 | Etzl, S, Winkler, A. | | 登録日 | 2018-01-15 | | 公開日 | 2018-04-18 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structure-guided design and functional characterization of an artificial red light-regulated guanylate/adenylate cyclase for optogenetic applications.
J. Biol. Chem., 293, 2018
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5LLY
 | | Photosensory Module of Bacteriophytochrome linked Diguanylyl Cyclase from Idiomarina species A28L | | 分子名称: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, CHLORIDE ION, Diguanylate cyclase (GGDEF) domain-containing protein, ... | | 著者 | Gourinchas, G, Winkler, A. | | 登録日 | 2016-07-28 | | 公開日 | 2017-03-15 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Long-range allosteric signaling in red light-regulated diguanylyl cyclases.
Sci Adv, 3, 2017
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5LLX
 | | Bacteriophytochrome activated diguanylyl cyclase from Idiomarina species A28L with GTP bound | | 分子名称: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, CHLORIDE ION, Diguanylate cyclase (GGDEF) domain-containing protein, ... | | 著者 | Gourinchas, G, Winkler, A. | | 登録日 | 2016-07-28 | | 公開日 | 2017-03-15 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Long-range allosteric signaling in red light-regulated diguanylyl cyclases.
Sci Adv, 3, 2017
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5LLW
 | | Bacteriophytochrome activated diguanylyl cyclase from Idiomarina species A28L | | 分子名称: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium-2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, CHLORIDE ION, Diguanylate cyclase (GGDEF) domain-containing protein | | 著者 | Gourinchas, G, Winkler, A. | | 登録日 | 2016-07-28 | | 公開日 | 2017-03-15 | | 最終更新日 | 2017-03-22 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Long-range allosteric signaling in red light-regulated diguanylyl cyclases.
Sci Adv, 3, 2017
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6C3L
 | | Crystal structure of BCL6 BTB domain with compound 15f | | 分子名称: | B-cell lymphoma 6 protein, N-[2-(1H-indol-3-yl)ethyl]-N'-{3-[(4-methylpiperazin-1-yl)methyl]-1-[2-(morpholin-4-yl)-2-oxoethyl]-1H-indol-6-yl}thiourea | | 著者 | Linhares, B, Cheng, H, Cierpicki, T, Xue, F. | | 登録日 | 2018-01-10 | | 公開日 | 2019-01-16 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.46092153 Å) | | 主引用文献 | Identification of Thiourea-Based Inhibitors of the B-Cell Lymphoma 6 BTB Domain via NMR-Based Fragment Screening and Computer-Aided Drug Design.
J.Med.Chem., 61, 2018
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3GR7
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3GR8
 | | Structure of OYE from Geobacillus kaustophilus, orthorhombic crystal form | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FLAVIN MONONUCLEOTIDE, NADPH dehydrogenase, ... | | 著者 | Uhl, M.K, Gruber, K. | | 登録日 | 2009-03-25 | | 公開日 | 2010-03-31 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Old Yellow Enzyme-Catalyzed Dehydrogenation of Saturated Ketones
ADV.SYNTH.CATAL., 353, 2011
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6WI7
 | | RING1B-BMI1 fusion in closed conformation | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, E3 ubiquitin-protein ligase RING2, Polycomb complex protein BMI-1 chimera, ... | | 著者 | Cho, H.J, Cierpicki, T. | | 登録日 | 2020-04-08 | | 公開日 | 2021-04-14 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.702 Å) | | 主引用文献 | Small-molecule inhibitors targeting Polycomb repressive complex 1 RING domain.
Nat.Chem.Biol., 17, 2021
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6WI8
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6C3N
 | | Crystal structure of BCL6 BTB domain in complex with compound 7CC5 | | 分子名称: | B-cell lymphoma 6 protein, N-(2-phenylethyl)-N'-pyridin-3-ylthiourea | | 著者 | Linhares, B, Cheng, H, Xue, F, Cierpicki, T. | | 登録日 | 2018-01-10 | | 公開日 | 2019-01-16 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.53170586 Å) | | 主引用文献 | Identification of Thiourea-Based Inhibitors of the B-Cell Lymphoma 6 BTB Domain via NMR-Based Fragment Screening and Computer-Aided Drug Design.
J.Med.Chem., 61, 2018
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6CQ1
 | | BCL6 BTB domain in complex with 15a | | 分子名称: | 2-{6-({[2-(1H-indol-3-yl)ethyl]carbamothioyl}amino)-3-[(4-methylpiperazin-1-yl)methyl]-1H-indol-1-yl}-N-(propan-2-yl)acetamide, B-cell lymphoma 6 protein | | 著者 | Linhares, B.M, Cheng, H, Xue, F, Cierpicki, T. | | 登録日 | 2018-03-14 | | 公開日 | 2019-03-20 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.69921041 Å) | | 主引用文献 | Identification of Thiourea-Based Inhibitors of the B-Cell Lymphoma 6 BTB Domain via NMR-Based Fragment Screening and Computer-Aided Drug Design.
J.Med.Chem., 61, 2018
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6FY4
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