6FHT

Crystal structure of an artificial phytochrome regulated adenylate/guanylate cyclase in its dark adapted Pr form

Summary for 6FHT

Entry DOI	10.2210/pdb6fht/pdb
Descriptor	Bacteriophytochrome,Adenylate cyclase, 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, SULFATE ION, ... (5 entities in total)
Functional Keywords	phytochrome, cyclase, lyase
Biological source	Deinococcus radiodurans More
Total number of polymer chains	2
Total formula weight	162498.01
Authors	Etzl, S.,Winkler, A. (deposition date: 2018-01-15, release date: 2018-04-18, Last modification date: 2024-01-17)
Primary citation	Etzl, S.,Lindner, R.,Nelson, M.D.,Winkler, A. Structure-guided design and functional characterization of an artificial red light-regulated guanylate/adenylate cyclase for optogenetic applications. J. Biol. Chem., 293:9078-9089, 2018 Cited by PubMed: 29695503 DOI: 10.1074/jbc.RA118.003069 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.35 Å)

Structure validation