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6FHT

Crystal structure of an artificial phytochrome regulated adenylate/guanylate cyclase in its dark adapted Pr form

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Bacteriophytochrome,Adenylate cyclasepolymer74179909.72UniProt (Q9RZA4)
UniProt (P72951)
Pfam (PF08446)
Pfam (PF01590)
Pfam (PF00360)
Pfam (PF00211)
Deinococcus radioduransPhytochrome-like protein
2C, K
(A, B)
3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acidnon-polymer585.72Chemie (LBV)
3D, E, F, G, H...
(A, B)
SULFATE IONnon-polymer96.110Chemie (SO4)
4J
(A)
DODECAETHYLENE GLYCOLnon-polymer546.61Chemie (12P)
5P, Q
(A, B)
waterwater18.0142Chemie (HOH)
Sequence modifications
A, B: 3 - 510 (UniProt: Q9RZA4)
PDBExternal DatabaseDetails
Gly -1-expression tag
Ala 0-expression tag
Met 1-expression tag
Ala 2-expression tag
A, B: 511 - 739 (UniProt: P72951)
PDBExternal DatabaseDetails
Lys 589Glu 488engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight159819.4
Non-Polymers*Number of molecules13
Total formula weight2678.6
All*Total formula weight162498.0
*Water molecules are not included.

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PDB entries from 2024-11-13

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