1IBE
| |
6DN2
| CRYSTAL STRUCTURE OF THE FMN RIBOSWITCH BOUND TO BRX1354 SPLIT RNA | 分子名称: | 4-{benzyl[2-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)ethyl]amino}butanoic acid, MAGNESIUM ION, POTASSIUM ION, ... | 著者 | Vicens, Q, Mondragon, E, Reyes, F.E, Berman, J, Kaur, H, Kells, K, Wickens, P, Wilson, J, Gadwood, R, Schostarez, H, Suto, R.K, Coish, P, Blount, K.F, Batey, R.T. | 登録日 | 2018-06-05 | 公開日 | 2018-09-05 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | 主引用文献 | Structure-Activity Relationship of Flavin Analogues That Target the Flavin Mononucleotide Riboswitch. ACS Chem. Biol., 13, 2018
|
|
6DN3
| CRYSTAL STRUCTURE OF THE FMN RIBOSWITCH BOUND TO BRX1555 SPLIT RNA | 分子名称: | 7,8-dimethyl-2,4-dioxo-10-(3-phenylpropyl)-1,2,3,4-tetrahydrobenzo[g]pteridin-10-ium, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Vicens, Q, Mondragon, E, Reyes, F.E, Berman, J, Kaur, H, Kells, K, Wickens, P, Wilson, J, Gadwood, R, Schostarez, H, Suto, R.K, Coish, P, Blount, K.F, Batey, R.T. | 登録日 | 2018-06-05 | 公開日 | 2018-09-05 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure-Activity Relationship of Flavin Analogues That Target the Flavin Mononucleotide Riboswitch. ACS Chem. Biol., 13, 2018
|
|
6DN1
| CRYSTAL STRUCTURE OF THE FMN RIBOSWITCH BOUND TO BRX1151 SPLIT RNA | 分子名称: | 10-(6-carboxyhexyl)-8-(cyclopentylamino)-2,4-dihydroxy-7-methylbenzo[g]pteridin-10-ium, MAGNESIUM ION, POTASSIUM ION, ... | 著者 | Vicens, Q, Mondragon, E, Reyes, F.E, Berman, J, Kaur, H, Kells, K, Wickens, P, Wilson, J, Gadwood, R, Schostarez, H, Suto, R.K, Coish, P, Blount, K.F, Batey, R.T. | 登録日 | 2018-06-05 | 公開日 | 2018-09-05 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | 主引用文献 | Structure-Activity Relationship of Flavin Analogues That Target the Flavin Mononucleotide Riboswitch. ACS Chem. Biol., 13, 2018
|
|
5LS6
| Structure of Human Polycomb Repressive Complex 2 (PRC2) with inhibitor | 分子名称: | 1-[(1~{R})-1-[1-[2,2-bis(fluoranyl)propyl]piperidin-4-yl]ethyl]-~{N}-[(4-methoxy-6-methyl-2-oxidanylidene-3~{H}-pyridin-3-yl)methyl]-2-methyl-indole-3-carboxamide, Histone-lysine N-methyltransferase EZH2,Histone-lysine N-methyltransferase EZH2,Histone-lysine N-methyltransferase EZH2, Jarid2 K116me3, ... | 著者 | Zhang, Y, Justin, N, Chen, S, Wilson, J, Gamblin, S. | 登録日 | 2016-08-22 | 公開日 | 2017-02-22 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.47 Å) | 主引用文献 | Identification of (R)-N-((4-Methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxamide (CPI-1205), a Potent and Selective Inhibitor of Histone Methyltransferase EZH2, Suitable for Phase I Clinical Trials for B-Cell Lymphomas. J. Med. Chem., 59, 2016
|
|
7QGQ
| |
6PGU
| |
5M5G
| Crystal structure of the Chaetomium Thermophilum polycomb repressive complex 2 (PRC2) | 分子名称: | Fragment from molecular 2 (region containing putative polycomb protein Suz12), HISTONE H3 11-Mer peptide, Putative uncharacterized protein, ... | 著者 | Zhang, Y, Justin, N, Wilson, J, Gamblin, S. | 登録日 | 2016-10-21 | 公開日 | 2017-01-11 | 最終更新日 | 2019-10-16 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Comment on "Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2". Science, 354, 2016
|
|
6PF1
| |
7ACW
| |
7ACY
| |
7ACX
| H/L (SLPH/SLPL) complex from C. difficile (R7404 strain) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, S-layer protein, SULFATE ION | 著者 | Lanzoni-Mangutchi, P, Barwinska-Sendra, A, Basle, A, El Omari, K, Wagner, A, Salgado, P.S. | 登録日 | 2020-09-11 | 公開日 | 2022-03-09 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Structure and assembly of the S-layer in C. difficile. Nat Commun, 13, 2022
|
|
7ACZ
| |
7ACV
| |
6UWY
| DYRK1A bound to a harmine derivative | 分子名称: | 4-(7-methoxy-1-methyl-9H-beta-carbolin-9-yl)butanamide, Dual specificity tyrosine-phosphorylation-regulated kinase 1A, TETRAETHYLENE GLYCOL | 著者 | Khamrui, S, Lazarus, M.B. | 登録日 | 2019-11-05 | 公開日 | 2020-02-12 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Synthesis and Biological Validation of a Harmine-Based, Central Nervous System (CNS)-Avoidant, Selective, Human beta-Cell Regenerative Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase A (DYRK1A) Inhibitor. J.Med.Chem., 63, 2020
|
|
1OUU
| CARBONMONOXY TROUT HEMOGLOBIN I | 分子名称: | CARBON MONOXIDE, HEMOGLOBIN I, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Tame, J, Wilson, J. | 登録日 | 1996-06-21 | 公開日 | 1997-01-11 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The crystal structures of trout Hb I in the deoxy and carbonmonoxy forms. J.Mol.Biol., 259, 1996
|
|
1OUT
| TROUT HEMOGLOBIN I | 分子名称: | HEMOGLOBIN I, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Tame, J, Wilson, J. | 登録日 | 1996-06-21 | 公開日 | 1997-01-11 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The crystal structures of trout Hb I in the deoxy and carbonmonoxy forms. J.Mol.Biol., 259, 1996
|
|
4IOV
| The structure of AAVrh32.33, a Novel Gene Delivery Vector | 分子名称: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, Capsid protein VP1 | 著者 | Mikalism, K, Nam, H.-J, Van vilet, K, Vandenberghe, L.H, Mays, L.E, McKenna, R, Wilson, J, Agbandje-McKenna, M. | 登録日 | 2013-01-08 | 公開日 | 2014-04-02 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | The structure of AAVrh32.33, a novel gene delivery vector. J.Struct.Biol., 186, 2014
|
|
8FG2
| SARS-CoV-2 Nucleocapsid dimer structure determined from COVID-19 patients | 分子名称: | Nucleoprotein | 著者 | Casasanta, M, Jonaid, G.M, Kaylor, L, Luqiu, W, DiCecco, L, Solares, M, Berry, S, Kelly, D.F. | 登録日 | 2022-12-12 | 公開日 | 2023-01-11 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (6 Å) | 主引用文献 | Structural Insights of the SARS-CoV-2 Nucleocapsid Protein: Implications for the Inner-workings of Rapid Antigen Tests. Microsc Microanal, 29, 2023
|
|
8FD5
| Nucleocapsid monomer structure from SARS-CoV-2 | 分子名称: | Nucleoprotein | 著者 | Casasanta, M, Jonaid, G.M, Kaylor, L, Luqiu, W, DiCecco, L, Solares, M, Berry, S, Kelly, D.F. | 登録日 | 2022-12-02 | 公開日 | 2023-01-11 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (4.57 Å) | 主引用文献 | Structural Insights of the SARS-CoV-2 Nucleocapsid Protein: Implications for the Inner-workings of Rapid Antigen Tests. Microsc Microanal, 29, 2023
|
|