7B9V
 
 | | Yeast C complex spliceosome at 2.8 Angstrom resolution with Prp18/Slu7 bound | | 分子名称: | 5' exon of UBC4 mRNA, BJ4_G0027490.mRNA.1.CDS.1, BJ4_G0054360.mRNA.1.CDS.1, ... | | 著者 | Wilkinson, M.E, Fica, S.M, Galej, W.P, Nagai, K. | | 登録日 | 2020-12-14 | | 公開日 | 2021-03-10 | | 最終更新日 | 2021-04-14 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structural basis for conformational equilibrium of the catalytic spliceosome.
Mol.Cell, 81, 2021
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8GH6
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5FCL
 | | Crystal structure of Cas1 from Pectobacterium atrosepticum | | 分子名称: | CRISPR-associated endonuclease Cas1 | | 著者 | Wilkinson, M.E, Nakatani, Y, Opel-Reading, H.K, Fineran, P.C, Krause, K.L. | | 登録日 | 2015-12-15 | | 公開日 | 2016-03-16 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural plasticity and in vivo activity of Cas1 from the type I-F CRISPR-Cas system.
Biochem.J., 473, 2016
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6EXN
 | | Post-catalytic P complex spliceosome with 3' splice site docked | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, Intron lariat: UBC4 RNA, ... | | 著者 | Wilkinson, M.E, Fica, S.M, Galej, W.P, Norman, C.M, Newman, A.J, Nagai, K. | | 登録日 | 2017-11-08 | | 公開日 | 2018-01-17 | | 最終更新日 | 2020-10-07 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Postcatalytic spliceosome structure reveals mechanism of 3'-splice site selection.
Science, 358, 2017
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8UYO
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8DGC
 | | Avs3 bound to phage PhiV-1 terminase | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, SeAvs3, ... | | 著者 | Wilkinson, M.E, Gao, L, Strecker, J, Makarova, K.S, Macrae, R.K, Koonin, E.V, Zhang, F. | | 登録日 | 2022-06-23 | | 公開日 | 2022-08-03 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Prokaryotic innate immunity through pattern recognition of conserved viral proteins.
Science, 377, 2022
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8DGF
 | | Avs4 bound to phage PhiV-1 portal | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding protein Avs4, MAGNESIUM ION, ... | | 著者 | Wilkinson, M.E, Gao, L, Strecker, J, Makarova, K.S, Macrae, R.K, Koonin, E.V, Zhang, F. | | 登録日 | 2022-06-23 | | 公開日 | 2022-08-03 | | 最終更新日 | 2022-08-24 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Prokaryotic innate immunity through pattern recognition of conserved viral proteins.
Science, 377, 2022
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5MPS
 | | Structure of a spliceosome remodeled for exon ligation | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Fica, S.M, Oubridge, C, Galej, W.P, Wilkinson, M.E, Newman, A.J, Bai, X.-C, Nagai, K. | | 登録日 | 2016-12-18 | | 公開日 | 2017-01-18 | | 最終更新日 | 2020-10-07 | | 実験手法 | ELECTRON MICROSCOPY (3.85 Å) | | 主引用文献 | Structure of a spliceosome remodelled for exon ligation.
Nature, 542, 2017
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5MQ0
 | | Structure of a spliceosome remodeled for exon ligation | | 分子名称: | 3'-EXON OF UBC4 PRE-MRNA, BOUND BY PRP22 HELICASE, 5'-EXON OF UBC4 PRE-MRNA, ... | | 著者 | Fica, S.M, Oubridge, C, Galej, W.P, Wilkinson, M.E, Newman, A.J, Bai, X.-C, Nagai, K. | | 登録日 | 2016-12-19 | | 公開日 | 2017-01-18 | | 最終更新日 | 2020-10-07 | | 実験手法 | ELECTRON MICROSCOPY (4.17 Å) | | 主引用文献 | Structure of a spliceosome remodelled for exon ligation.
Nature, 542, 2017
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6QDV
 | | Human post-catalytic P complex spliceosome | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | | 著者 | Fica, S.M, Oubridge, C, Wilkinson, M.E, Newman, A.J, Nagai, K. | | 登録日 | 2019-01-03 | | 公開日 | 2019-02-20 | | 最終更新日 | 2020-10-07 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | A human postcatalytic spliceosome structure reveals essential roles of metazoan factors for exon ligation.
Science, 363, 2019
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8EEY
 | | Cas7-11 in complex with DR-mismatched target RNA, Csx29 and Csx30 | | 分子名称: | Cas7-11, Csx29, Csx30, ... | | 著者 | Demircioglu, F.E, Wilkinson, M.E, Strecker, J, Li, D, Faure, G, Macrae, R.K, Zhang, F. | | 登録日 | 2022-09-07 | | 公開日 | 2022-11-16 | | 最終更新日 | 2022-12-07 | | 実験手法 | ELECTRON MICROSCOPY (2.53 Å) | | 主引用文献 | RNA-activated protein cleavage with a CRISPR-associated endopeptidase.
Science, 378, 2022
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8EEX
 | | Cas7-11 in complex with Csx29 | | 分子名称: | Cas7-11, Csx29, ZINC ION, ... | | 著者 | Demircioglu, F.E, Wilkinson, M.E, Strecker, J, Li, D, Faure, G, Macrae, R.K, Zhang, F. | | 登録日 | 2022-09-07 | | 公開日 | 2022-11-16 | | 最終更新日 | 2022-12-07 | | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | | 主引用文献 | RNA-activated protein cleavage with a CRISPR-associated endopeptidase.
Science, 378, 2022
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6QW6
 | | Structure of the human U5.U4/U6 tri-snRNP at 2.9A resolution. | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | | 著者 | Charenton, C, Wilkinson, M.E, Nagai, K. | | 登録日 | 2019-03-05 | | 公開日 | 2019-04-17 | | 最終更新日 | 2020-10-07 | | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | | 主引用文献 | Mechanism of 5' splice site transfer for human spliceosome activation.
Science, 364, 2019
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6QX9
 | | Structure of a human fully-assembled precatalytic spliceosome (pre-B complex). | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, AdML pre-mRNA, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Charenton, C, Wilkinson, M.E, Nagai, K. | | 登録日 | 2019-03-07 | | 公開日 | 2019-04-17 | | 最終更新日 | 2020-10-07 | | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | | 主引用文献 | Mechanism of 5' splice site transfer for human spliceosome activation.
Science, 364, 2019
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5LJ3
 | | Structure of the core of the yeast spliceosome immediately after branching | | 分子名称: | CEF1, CLF1, CWC15, ... | | 著者 | Galej, W.P, Wilkinson, M.F, Fica, S.M, Oubridge, C, Newman, A.J, Nagai, K. | | 登録日 | 2016-07-17 | | 公開日 | 2016-08-03 | | 最終更新日 | 2019-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Cryo-EM structure of the spliceosome immediately after branching.
Nature, 537, 2016
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5LJ5
 | | Overall structure of the yeast spliceosome immediately after branching. | | 分子名称: | CWC15, CWC22, Exon 1 (5' exon) of UBC4 pre-mRNA, ... | | 著者 | Galej, W.P, Wilkinson, M.F, Fica, S.M, Oubridge, C, Newman, A.J, Nagai, K. | | 登録日 | 2016-07-17 | | 公開日 | 2016-08-31 | | 最終更新日 | 2019-12-11 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Cryo-EM structure of the spliceosome immediately after branching.
Nature, 537, 2016
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8DMB
 | | Structure of Desulfovirgula thermocuniculi IsrB (DtIsrB) in complex with omega RNA and target DNA | | 分子名称: | MAGNESIUM ION, Ubiquitin-like protein SMT3,IsrB protein,monomeric superfolder Green Fluorescent Protein, non-target DNA, ... | | 著者 | Seiichi, H, Kappel, K, Zhang, F. | | 登録日 | 2022-07-08 | | 公開日 | 2022-10-19 | | 最終更新日 | 2022-10-26 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structure of the OMEGA nickase IsrB in complex with omega RNA and target DNA.
Nature, 610, 2022
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