5WWC
 
 | | The crystal structure of Cren7 mutant L28M in complex with dsDNA | | 分子名称: | Chromatin protein Cren7, DNA (5'-D(*GP*TP*AP*AP*TP*TP*AP*C)-3') | | 著者 | Zhang, Z.F, Zhao, M.H, Wang, L, Chen, Y.Y, Dong, Y.H, Gong, Y, Huang, L. | | 登録日 | 2016-12-31 | | 公開日 | 2017-04-26 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Roles of Leu28 side chain intercalation in the interaction between Cren7 and DNA
Biochem. J., 474, 2017
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6A2H
 | | Architectural roles of Cren7 in folding crenarchaeal chromatin filament | | 分子名称: | Chromatin protein Cren7, DNA (5'-D(P*AP*AP*TP*TP*AP*C)-3'), DNA (5'-D(P*GP*TP*AP*AP*TP*T)-3') | | 著者 | Zhang, Z.F, Zhao, M.H, Chen, Y.Y, Wang, L, Dong, Y.H, Gong, Y, Huang, L. | | 登録日 | 2018-06-11 | | 公開日 | 2019-01-16 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Architectural roles of Cren7 in folding crenarchaeal chromatin filament.
Mol. Microbiol., 111, 2019
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6A2I
 | | Architectural roles of Cren7 in folding crenarchaeal chromatin filament | | 分子名称: | Chromatin protein Cren7, DNA (5'-D(*CP*GP*TP*AP*GP*CP*TP*AP*AP*TP*TP*AP*GP*CP*TP*AP*CP*G)-3') | | 著者 | Zhang, Z.F, Zhao, M.H, Chen, Y.Y, Wang, L, Dong, Y.H, Gong, Y, Huang, L. | | 登録日 | 2018-06-11 | | 公開日 | 2019-01-16 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Architectural roles of Cren7 in folding crenarchaeal chromatin filament.
Mol. Microbiol., 111, 2019
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2ODA
 | | Crystal Structure of PSPTO_2114 | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Hypothetical protein PSPTO_2114, MAGNESIUM ION | | 著者 | Peisach, E, Allen, K.N, Dunaway-Mariano, D, Wang, L, Burroughs, A.M, Aravind, L. | | 登録日 | 2006-12-22 | | 公開日 | 2007-09-04 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The X-ray crystallographic structure and activity analysis of a Pseudomonas-specific subfamily of the HAD enzyme superfamily evidences a novel biochemical function.
Proteins, 70, 2007
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3JCM
 | | Cryo-EM structure of the spliceosomal U4/U6.U5 tri-snRNP | | 分子名称: | 13 kDa ribonucleoprotein-associated protein, GUANOSINE-5'-TRIPHOSPHATE, N,N,7-trimethylguanosine 5'-(trihydrogen diphosphate), ... | | 著者 | Wan, R, Yan, C, Bai, R, Wang, L, Huang, M, Wong, C.C, Shi, Y. | | 登録日 | 2015-12-23 | | 公開日 | 2016-02-24 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | The 3.8 angstrom structure of the U4/U6.U5 tri-snRNP: Insights into spliceosome assembly and catalysis
Science, 351, 2016
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6KZW
 | | Crystal structure of YggS family pyridoxal phosphate-dependent enzyme PipY from Fusobacterium nucleatum | | 分子名称: | PHOSPHATE ION, Pyridoxal phosphate homeostasis protein | | 著者 | Chen, Y, Wang, L, Shang, F, Lan, J, Liu, W, Xu, Y. | | 登録日 | 2019-09-25 | | 公開日 | 2019-10-16 | | 最終更新日 | 2021-01-13 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Crystal structure of YggS family pyridoxal phosphate-dependent enzyme PipY from Fusobacterium nucleatum
To Be Published
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3KO1
 | | Cystal structure of thermosome from Acidianus tengchongensis strain S5 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Chaperonin | | 著者 | Huo, Y, Zhang, K, Hu, Z, Wang, L, Zhai, Y, Zhou, Q, Lander, G, He, Y, Zhu, J, Xu, W, Dong, Z, Sun, F. | | 登録日 | 2009-11-12 | | 公開日 | 2010-11-03 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Crystal structure of group II chaperonin in the open state.
Structure, 18, 2010
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6LQI
 | | Cryo-EM structure of the mouse Piezo1 isoform Piezo1.1 | | 分子名称: | Piezo-type mechanosensitive ion channel component 1 | | 著者 | Geng, J, Liu, W, Zhou, H, Zhang, T, Wang, L, Zhang, M, Shen, B, Li, X, Xiao, B. | | 登録日 | 2020-01-13 | | 公開日 | 2020-03-04 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | A Plug-and-Latch Mechanism for Gating the Mechanosensitive Piezo Channel.
Neuron, 106, 2020
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4E8C
 | | Crystal structure of streptococcal beta-galactosidase in complex with galactose | | 分子名称: | GLYCEROL, Glycosyl hydrolase, family 35, ... | | 著者 | Cheng, W, Wang, L, Bai, X.H, Jiang, Y.L, Li, Q, Yu, G, Zhou, C.Z, Chen, Y.X. | | 登録日 | 2012-03-20 | | 公開日 | 2012-05-30 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural insights into the substrate specificity of Streptococcus pneumoniae beta (1,3)-galactosidase BgaC
J.Biol.Chem., 287, 2012
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4E8D
 | | Crystal structure of streptococcal beta-galactosidase | | 分子名称: | GLYCEROL, Glycosyl hydrolase, family 35 | | 著者 | Cheng, W, Wang, L, Bai, X.H, Jiang, Y.L, Li, Q, Yu, G, Zhou, C.Z, Chen, Y.X. | | 登録日 | 2012-03-20 | | 公開日 | 2012-05-30 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural insights into the substrate specificity of Streptococcus pneumoniae beta (1,3)-galactosidase BgaC
J.Biol.Chem., 287, 2012
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6M4O
 | | Cryo-EM structure of the monomeric SPT-ORMDL3 complex | | 分子名称: | ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ... | | 著者 | Li, S.S, Xie, T, Wang, L, Gong, X. | | 登録日 | 2020-03-08 | | 公開日 | 2021-02-10 | | 最終更新日 | 2021-03-24 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural insights into the assembly and substrate selectivity of human SPT-ORMDL3 complex.
Nat.Struct.Mol.Biol., 28, 2021
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6M4N
 | | Cryo-EM structure of the dimeric SPT-ORMDL3 complex | | 分子名称: | ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ... | | 著者 | Li, S.S, Xie, T, Wang, L, Gong, X. | | 登録日 | 2020-03-07 | | 公開日 | 2021-02-10 | | 最終更新日 | 2021-03-24 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structural insights into the assembly and substrate selectivity of human SPT-ORMDL3 complex.
Nat.Struct.Mol.Biol., 28, 2021
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7E6T
 | | Structural insights into the activation of human calcium-sensing receptor | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CYCLOMETHYLTRYPTOPHAN, ... | | 著者 | Geng, Y, Chen, X.C, Wang, L, Cui, Q.Q, Ding, Z.Y, Han, L, Kou, Y.J, Zhang, W.Q, Wang, H.N, Jia, X.M, Dai, M, Shi, Z.Z, Li, Y.Y, Li, X.Y. | | 登録日 | 2021-02-24 | | 公開日 | 2021-09-22 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural insights into the activation of human calcium-sensing receptor.
Elife, 10, 2021
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7E6U
 | | the complex of inactive CaSR and NB2D11 | | 分子名称: | Extracellular calcium-sensing receptor, NB-2D11 | | 著者 | Geng, Y, Chen, X.C, Wang, L, Cui, Q.Q, Ding, Z.Y, Han, L, Kou, Y.J, Zhang, W.Q, Wang, H.N, Jia, X.M, Dai, M, Shi, Z.Z, Li, Y.Y, Li, X.Y. | | 登録日 | 2021-02-24 | | 公開日 | 2021-09-22 | | 実験手法 | ELECTRON MICROSCOPY (6 Å) | | 主引用文献 | Structural insights into the activation of human calcium-sensing receptor.
Elife, 10, 2021
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6IF8
 | | Aeromonas hydrophila MtaN-2 complexed with adenine | | 分子名称: | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, ADENINE | | 著者 | Chen, J, Liu, W, Wang, L, Shang, F, Lan, J, Chen, Y, Xu, Y. | | 登録日 | 2018-09-18 | | 公開日 | 2018-10-03 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Aeromonas hydrophila MtaN-2 complexed with adenine
To Be Published
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7ENQ
 | | Crystal structure of human NAMPT in complex with compound NAT | | 分子名称: | 2-(2-~{tert}-butylphenoxy)-~{N}-(4-hydroxyphenyl)ethanamide, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION | | 著者 | Wang, G, Wu, C, Liu, M, Yao, H, Li, C, Wang, L, Tang, Y. | | 登録日 | 2021-04-19 | | 公開日 | 2022-05-04 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.204966 Å) | | 主引用文献 | Discovery of small-molecule activators of nicotinamide phosphoribosyltransferase (NAMPT) and their preclinical neuroprotective activity.
Cell Res., 32, 2022
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6K28
 | | Crystal structure of the 5-(Hydroxyethyl)-methylthiazole Kinase ThiM from Klebsiella pneumonia in complex with TZE | | 分子名称: | 2-(4-METHYL-THIAZOL-5-YL)-ETHANOL, Hydroxyethylthiazole kinase, MAGNESIUM ION | | 著者 | Chen, Y, Wang, L, Shang, F, Lan, J, Liu, W, Xu, Y. | | 登録日 | 2019-05-13 | | 公開日 | 2019-07-10 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.002 Å) | | 主引用文献 | Structural insight of the 5-(Hydroxyethyl)-methylthiazole kinase ThiM involving vitamin B1 biosynthetic pathway from the Klebsiella pneumoniae.
Biochem.Biophys.Res.Commun., 518, 2019
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6JYY
 | | Crystal structure of the 5-(Hydroxyethyl)-methylthiazole Kinase ThiM from Klebsiella pneumonia | | 分子名称: | Hydroxyethylthiazole kinase | | 著者 | Chen, Y, Wang, L, Shang, F, Lan, J, Liu, W, Xu, Y. | | 登録日 | 2019-04-29 | | 公開日 | 2019-06-26 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural insight of the 5-(Hydroxyethyl)-methylthiazole kinase ThiM involving vitamin B1 biosynthetic pathway from the Klebsiella pneumoniae.
Biochem.Biophys.Res.Commun., 518, 2019
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6K63
 | | The crystal structure of cytidine deaminase from Klebsiella pneumoniae | | 分子名称: | 1,4-DIETHYLENE DIOXIDE, Cytidine deaminase, ZINC ION | | 著者 | Liu, W, Shang, F, Lan, J, Chen, Y, Wang, L, Xu, Y. | | 登録日 | 2019-06-01 | | 公開日 | 2019-07-31 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.073 Å) | | 主引用文献 | Biochemical and structural analysis of the Klebsiella pneumoniae cytidine deaminase CDA.
Biochem.Biophys.Res.Commun., 519, 2019
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6K2Q
 | | Aeromonas hydrophila MtaN-2 complexed with adenine | | 分子名称: | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, ADENINE | | 著者 | Chen, J, Liu, W, Wang, L, Shang, F, Lan, J, Chen, Y, Xu, Y. | | 登録日 | 2019-05-15 | | 公開日 | 2019-05-29 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structure of Aeromonas hydrophila Cytoplasmic 5'-Methylthioadenosine/S-Adenosylhomocysteine Nucleosidase.
Biochemistry, 58, 2019
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4JI6
 | | Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | | 分子名称: | 16S rRNA, MAGNESIUM ION, RIBOSOMAL PROTEIN S10, ... | | 著者 | Demirci, H, Wang, L, Murphy IV, F, Murphy, E, Carr, J, Blanchard, S, Jogl, G, Dahlberg, A.E, Gregory, S.T. | | 登録日 | 2013-03-05 | | 公開日 | 2013-11-06 | | 最終更新日 | 2013-12-04 | | 実験手法 | X-RAY DIFFRACTION (3.55 Å) | | 主引用文献 | The central role of protein S12 in organizing the structure of the decoding site of the ribosome.
Rna, 19, 2013
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4JI2
 | | Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | | 分子名称: | 16S rRNA, MAGNESIUM ION, RIBOSOMAL PROTEIN S10, ... | | 著者 | Demirci, H, Wang, L, Murphy IV, F, Murphy, E, Carr, J, Blanchard, S, Jogl, G, Dahlberg, A.E, Gregory, S.T. | | 登録日 | 2013-03-05 | | 公開日 | 2013-11-06 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.64 Å) | | 主引用文献 | The central role of protein S12 in organizing the structure of the decoding site of the ribosome.
Rna, 19, 2013
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4JI4
 | | Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | | 分子名称: | 16S rRNA, MAGNESIUM ION, RIBOSOMAL PROTEIN S10, ... | | 著者 | Demirci, H, Wang, L, Murphy IV, F, Murphy, E, Carr, J, Blanchard, S, Jogl, G, Dahlberg, A.E, Gregory, S.T. | | 登録日 | 2013-03-05 | | 公開日 | 2013-11-06 | | 最終更新日 | 2013-12-04 | | 実験手法 | X-RAY DIFFRACTION (3.692 Å) | | 主引用文献 | The central role of protein S12 in organizing the structure of the decoding site of the ribosome.
Rna, 19, 2013
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4JI8
 | | Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | | 分子名称: | 16S rRNA, MAGNESIUM ION, RIBOSOMAL PROTEIN S10, ... | | 著者 | Demirci, H, Wang, L, Murphy IV, F, Murphy, E, Carr, J, Blanchard, S, Jogl, G, Dahlberg, A.E, Gregory, S.T. | | 登録日 | 2013-03-05 | | 公開日 | 2013-11-06 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.742 Å) | | 主引用文献 | The central role of protein S12 in organizing the structure of the decoding site of the ribosome.
Rna, 19, 2013
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4JI0
 | | Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | | 分子名称: | 16S rRNA, MAGNESIUM ION, ZINC ION, ... | | 著者 | Demirci, H, Wang, L, Murphy IV, F, Murphy, E, Carr, J, Blanchard, S, Jogl, G, Dahlberg, A.E, Gregory, S.T. | | 登録日 | 2013-03-05 | | 公開日 | 2013-11-06 | | 最終更新日 | 2013-12-04 | | 実験手法 | X-RAY DIFFRACTION (3.492 Å) | | 主引用文献 | The central role of protein S12 in organizing the structure of the decoding site of the ribosome.
Rna, 19, 2013
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