8D4X
| Structure of the human UBR5 HECT-type E3 ubiquitin ligase in a dimeric form | Descriptor: | E3 ubiquitin-protein ligase UBR5, ZINC ION | Authors: | Wang, F, He, Q, Lin, G, Li, H. | Deposit date: | 2022-06-02 | Release date: | 2023-04-19 | Last modified: | 2023-05-17 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structure of the human UBR5 E3 ubiquitin ligase. Structure, 31, 2023
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4ZAH
| Crystal structure of sugar aminotransferase WecE with External Aldimine VII from Escherichia coli K-12 | Descriptor: | [[(2R,3S,5R)-5-[5-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2R,3R,4S,5R,6R)-6-methyl-5-[(E)-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]-3,4-bis(oxidanyl)oxan-2-yl] hydrogen phosphate, dTDP-4-amino-4,6-dideoxygalactose transaminase | Authors: | Wang, F, Singh, S, Cao, H, Xu, W, Miller, M.D, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | Deposit date: | 2015-04-13 | Release date: | 2015-04-29 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Structural Basis for the Stereochemical Control of Amine Installation in Nucleotide Sugar Aminotransferases. Acs Chem.Biol., 10, 2015
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4ZAS
| Crystal structure of sugar aminotransferase CalS13 from Micromonospora echinospora | Descriptor: | CalS13, SULFATE ION, THYMIDINE-5'-DIPHOSPHATE, ... | Authors: | Wang, F, Singh, S, Miller, M.D, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | Deposit date: | 2015-04-13 | Release date: | 2015-04-29 | Last modified: | 2019-12-04 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Structure characterization of sugar aminotransferases CalS13 and WecE provides the basis for a unifying structural model for stereochemical outcome. To Be Published
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6UQC
| Mouse IgG2a Bispecific Fc | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Wang, F, Tsai, J.C, Davis, J.H, West, S.M, Strop, P. | Deposit date: | 2019-10-18 | Release date: | 2020-01-01 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Design and characterization of mouse IgG1 and IgG2a bispecific antibodies for use in syngeneic models. Mabs, 12, 2019
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6V7B
| Cryo-EM reconstruction of Pyrobaculum filamentous virus 2 (PFV2) | Descriptor: | A-DNA, Structural protein VP1, Structural protein VP2 | Authors: | Wang, F, Baquero, D.P, Su, Z, Prangishvili, D, Krupovic, M, Egelman, E.H. | Deposit date: | 2019-12-08 | Release date: | 2020-04-01 | Last modified: | 2020-05-20 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structure of a filamentous virus uncovers familial ties within the archaeal virosphere. Virus Evol, 6, 2020
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6W8U
| Cryo-EM of the Pyrobaculum arsenaticum pilus | Descriptor: | pilin | Authors: | Wang, F, Baquero, D.P, Su, Z, Beltran, L.C, Prangishvili, D, Krupovic, M, Egelman, E.H. | Deposit date: | 2020-03-21 | Release date: | 2020-07-08 | Last modified: | 2021-10-06 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | The structures of two archaeal type IV pili illuminate evolutionary relationships. Nat Commun, 11, 2020
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6W8X
| Cryo-EM of the S. solfataricus pilus | Descriptor: | pilin | Authors: | Wang, F, Baquero, D.P, Su, Z, Beltran, L.C, Prangishvili, D, Krupovic, M, Egelman, E.H. | Deposit date: | 2020-03-21 | Release date: | 2020-07-08 | Last modified: | 2021-10-06 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | The structures of two archaeal type IV pili illuminate evolutionary relationships. Nat Commun, 11, 2020
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6WL7
| Cryo-EM of Form 2 like peptide filament, 29-20-2 | Descriptor: | peptide 29-20-2 | Authors: | Wang, F, Gnewou, O.M, Modlin, C, Egelman, E.H, Conticello, V.P. | Deposit date: | 2020-04-18 | Release date: | 2020-12-02 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural analysis of cross alpha-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials. Nat Commun, 12, 2021
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6WKX
| Cryo-EM of Form 1 related peptide filament, 15-10-3 | Descriptor: | peptide 15-10-3 | Authors: | Wang, F, Gnewou, O.M, Egelman, E.H, Conticello, V.P. | Deposit date: | 2020-04-17 | Release date: | 2020-12-02 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural analysis of cross alpha-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials. Nat Commun, 12, 2021
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6WL1
| Cryo-EM of Form 1 related peptide filament, 36-31-3 | Descriptor: | peptide 36-31-3 | Authors: | Wang, F, Gnewou, O.M, Modlin, C, Egelman, E.H, Conticello, V.P. | Deposit date: | 2020-04-17 | Release date: | 2020-12-02 | Last modified: | 2021-12-15 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural analysis of cross alpha-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials. Nat Commun, 12, 2021
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6WL0
| Cryo-EM of Form 1 related peptide filament, 36-31-3-RD | Descriptor: | peptide 36-31-3-RD | Authors: | Wang, F, Gnewou, O.M, Su, Z, Egelman, E.H, Conticello, V.P. | Deposit date: | 2020-04-17 | Release date: | 2020-12-02 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Structural analysis of cross alpha-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials. Nat Commun, 12, 2021
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6WL8
| Cryo-EM of Form 2 peptide filament | Descriptor: | Form 2 peptide | Authors: | Wang, F, Gnewou, O.M, Xu, C, Su, Z, Egelman, E.H, Conticello, V.P. | Deposit date: | 2020-04-18 | Release date: | 2020-12-02 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural analysis of cross alpha-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials. Nat Commun, 12, 2021
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6WL9
| Cryo-EM of Form 2 like peptide filament, Form2a | Descriptor: | peptide Form2a | Authors: | Wang, F, Beltran, L.C, Gnewou, O.M, Egelman, E.H, Conticello, V.P. | Deposit date: | 2020-04-18 | Release date: | 2020-12-02 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural analysis of cross alpha-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials. Nat Commun, 12, 2021
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6WKY
| Cryo-EM of Form 1 related peptide filament, 29-24-3 | Descriptor: | peptide 29-24-3 | Authors: | Wang, F, Gnewou, O.M, Egelman, E.H, Conticello, V.P. | Deposit date: | 2020-04-17 | Release date: | 2020-12-02 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural analysis of cross alpha-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials. Nat Commun, 12, 2021
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6WQ2
| Cryo-EM of the S. islandicus filamentous virus, SIFV | Descriptor: | A-DNA, Structural protein MCP1, Structural protein MCP2 | Authors: | Wang, F, Baquero, D.P, Su, Z, Zheng, W, Prangishvili, D, Krupovic, M, Egelman, E.H. | Deposit date: | 2020-04-28 | Release date: | 2020-07-29 | Last modified: | 2021-10-06 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structures of filamentous viruses infecting hyperthermophilic archaea explain DNA stabilization in extreme environments. Proc.Natl.Acad.Sci.USA, 117, 2020
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6WQ0
| Cryo-EM of the S. solfataricus rod-shaped virus, SSRV1 | Descriptor: | DNA (301-MER), Structural protein | Authors: | Wang, F, Baquero, D.P, Beltran, L.C, Prangishvili, D, Krupovic, M, Egelman, E.H. | Deposit date: | 2020-04-28 | Release date: | 2020-07-29 | Last modified: | 2021-10-06 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structures of filamentous viruses infecting hyperthermophilic archaea explain DNA stabilization in extreme environments. Proc.Natl.Acad.Sci.USA, 117, 2020
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5EJL
| MrkH, A novel c-di-GMP dependence transcription regulatory factor. | Descriptor: | 1,2-ETHANEDIOL, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Klebsiella pneumoniae genome assembly NOVST, ... | Authors: | Wang, F, Zhu, D, Gu, L. | Deposit date: | 2015-11-02 | Release date: | 2016-10-19 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The PilZ domain of MrkH represents a novel DNA binding motif Protein Cell, 7, 2016
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7ESF
| The Crystal Structure of human MTH1 from Biortus | Descriptor: | 7,8-dihydro-8-oxoguanine triphosphatase, DI(HYDROXYETHYL)ETHER, TETRAETHYLENE GLYCOL | Authors: | Wang, F, Cheng, W, Shang, H, Wang, R, Zhang, B, Tian, F. | Deposit date: | 2021-05-10 | Release date: | 2021-05-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | The Crystal Structure of human MTH1 from Biortus To Be Published
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7RX4
| Cryo-EM reconstruction of AS2 nanotube (Form II like) | Descriptor: | AS2 peptide | Authors: | Wang, F, Gnewou, O.M, Solemanifar, A, Xu, C, Egelman, E.H, Conticello, V.P. | Deposit date: | 2021-08-21 | Release date: | 2021-09-08 | Last modified: | 2022-09-28 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Cryo-EM of Helical Polymers. Chem.Rev., 122, 2022
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7RX5
| Cryo-EM reconstruction of Form1-N2 nanotube (Form I like) | Descriptor: | F1-N2 nanotube | Authors: | Wang, F, Gnewou, O.M, Solemanifar, A, Xu, C, Egelman, E.H, Conticello, V.P. | Deposit date: | 2021-08-21 | Release date: | 2021-09-08 | Last modified: | 2022-09-28 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM of Helical Polymers. Chem.Rev., 122, 2022
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7RO6
| Cryo-EM reconstruction of Sulfolobus monocaudavirus SMV1, symmetry 5 | Descriptor: | major capsid protein | Authors: | Wang, F, Cvirkaite-Krupovic, V, Krupovic, M, Egelman, E.H. | Deposit date: | 2021-07-30 | Release date: | 2022-03-30 | Last modified: | 2022-04-27 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Spindle-shaped archaeal viruses evolved from rod-shaped ancestors to package a larger genome. Cell, 185, 2022
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7ROG
| Cryo-EM reconstruction of Sulfolobus monocaudavirus SMV1, symmetry 10 | Descriptor: | major capsid protein | Authors: | Wang, F, Cvirkaite-Krupovic, V, Krupovic, M, Egelman, E.H. | Deposit date: | 2021-07-30 | Release date: | 2022-03-30 | Last modified: | 2022-04-27 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Spindle-shaped archaeal viruses evolved from rod-shaped ancestors to package a larger genome. Cell, 185, 2022
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7ROH
| Cryo-EM reconstruction of Sulfolobus monocaudavirus SMV1, symmetry 11 | Descriptor: | major capsid protein | Authors: | Wang, F, Cvirkaite-Krupovic, V, Krupovic, M, Egelman, E.H. | Deposit date: | 2021-07-30 | Release date: | 2022-03-30 | Last modified: | 2022-04-27 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Spindle-shaped archaeal viruses evolved from rod-shaped ancestors to package a larger genome. Cell, 185, 2022
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7RO3
| Cryo-EM reconstruction of Sulfolobus monocaudavirus SMV1, symmetry 2 | Descriptor: | major capsid protein | Authors: | Wang, F, Cvirkaite-Krupovic, V, Krupovic, M, Egelman, E.H. | Deposit date: | 2021-07-30 | Release date: | 2022-03-30 | Last modified: | 2022-04-27 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Spindle-shaped archaeal viruses evolved from rod-shaped ancestors to package a larger genome. Cell, 185, 2022
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7RO2
| Cryo-EM reconstruction of Sulfolobus monocaudavirus SMV1, symmetry 1 | Descriptor: | major capsid protein | Authors: | Wang, F, Cvirkaite-Krupovic, V, Krupovic, M, Egelman, E.H. | Deposit date: | 2021-07-30 | Release date: | 2022-03-30 | Last modified: | 2022-04-27 | Method: | ELECTRON MICROSCOPY (5.1 Å) | Cite: | Spindle-shaped archaeal viruses evolved from rod-shaped ancestors to package a larger genome. Cell, 185, 2022
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