4ZAH
Crystal structure of sugar aminotransferase WecE with External Aldimine VII from Escherichia coli K-12
Replaces: 4WFPSummary for 4ZAH
Entry DOI | 10.2210/pdb4zah/pdb |
Related | 4PIW |
Descriptor | dTDP-4-amino-4,6-dideoxygalactose transaminase, [[(2R,3S,5R)-5-[5-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2R,3R,4S,5R,6R)-6-methyl-5-[(E)-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]-3,4-bis(oxidanyl)oxan-2-yl] hydrogen phosphate (3 entities in total) |
Functional Keywords | sugar aminotransferase, structural genomics, psi-biology, protein structure initiative, enzyme discovery for natural product biosynthesis, natpro, transferase |
Biological source | Escherichia coli (strain K12) |
Total number of polymer chains | 8 |
Total formula weight | 359149.90 |
Authors | Wang, F.,Singh, S.,Cao, H.,Xu, W.,Miller, M.D.,Thorson, J.S.,Phillips Jr., G.N.,Enzyme Discovery for Natural Product Biosynthesis (NatPro) (deposition date: 2015-04-13, release date: 2015-04-29, Last modification date: 2023-09-27) |
Primary citation | Wang, F.,Singh, S.,Xu, W.,Helmich, K.E.,Miller, M.D.,Cao, H.,Bingman, C.A.,Thorson, J.S.,Phillips, G.N. Structural Basis for the Stereochemical Control of Amine Installation in Nucleotide Sugar Aminotransferases. Acs Chem.Biol., 10:2048-2056, 2015 Cited by PubMed: 26023720DOI: 10.1021/acschembio.5b00244 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.24 Å) |
Structure validation
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