8ESM
| Human triacylglycerol synthesizing enzyme DGAT1 in complex with T863 inhibitor | Descriptor: | Diacylglycerol O-acyltransferase 1, {(1r,4r)-4-[4-(4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]cyclohexyl}acetic acid | Authors: | Sui, X, Kun, W, Walther, T, Farese, R, Liao, M. | Deposit date: | 2022-10-14 | Release date: | 2023-06-07 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Mechanism of action for small-molecule inhibitors of triacylglycerol synthesis. Nat Commun, 14, 2023
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8ETM
| Human triacylglycerol synthesizing enzyme DGAT1 in complex with DGAT1IN1 inhibitor | Descriptor: | Diacylglycerol O-acyltransferase 1, [(1S,4r)-4-{4-[(4S)-2-({[4-(trifluoromethoxy)phenyl]methyl}carbamoyl)imidazo[1,2-a]pyridin-6-yl]phenyl}cyclohexyl]acetic acid | Authors: | Sui, X, Kun, W, Walther, T, Farese, R, Liao, M. | Deposit date: | 2022-10-17 | Release date: | 2023-06-07 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Mechanism of action for small-molecule inhibitors of triacylglycerol synthesis. Nat Commun, 14, 2023
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