5BMG
| Nitroxide Spin Labels in Protein GB1: E15 Mutant | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Immunoglobulin G-binding protein G, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate | 著者 | Cunningham, T.C, Horne, W.S, Saxena, S. | 登録日 | 2015-05-22 | 公開日 | 2016-04-06 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Rotameric preferences of a protein spin label at edge-strand beta-sheet sites. Protein Sci., 25, 2016
|
|
6OLN
| |
5DIC
| |
5DQV
| |
5DQW
| |
2OXJ
| Helix Bundle Quaternary Structure from alpha/beta-Peptide Foldamers: GCN4-p1 with beta-residues at b and f heptad positions. | 分子名称: | ACETATE ION, hybrid alpha/beta peptide based on the GCN4-p1 sequence; heptad positions b and f substituted with beta-amino acids | 著者 | Horne, W.S, Price, J.L, Keck, J.L, Gellman, S.H. | 登録日 | 2007-02-20 | 公開日 | 2007-03-27 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Helix Bundle Quaternary Structure from alpha/beta-Peptide Foldamers. J.Am.Chem.Soc., 129, 2007
|
|
3O3Y
| |
2OXK
| Helix Bundle Quaternary Structure from alpha/beta-Peptide Foldamers: GCN4-pLI with beta-residues at b and f heptad positions. | 分子名称: | FORMIC ACID, hybrid alpha/beta peptide based on the GCN4-pLI sequence; heptad positions b and f substituted with beta-amino acids | 著者 | Horne, W.S, Price, J.L, Keck, J.L, Gellman, S.H. | 登録日 | 2007-02-20 | 公開日 | 2007-03-27 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Helix Bundle Quaternary Structure from alpha/beta-Peptide Foldamers. J.Am.Chem.Soc., 129, 2007
|
|
6CU7
| Alpha Synuclein fibril formed by full length protein - Rod Polymorph | 分子名称: | Alpha-synuclein | 著者 | Li, B, Hatami, A, Ge, P, Murray, K.A, Sheth, P, Zhang, M, Nair, G, Sawaya, M.R, Zhu, C, Broad, M, Shin, W.S, Ye, S, John, V, Eisenberg, D.S, Zhou, Z.H, Jiang, L. | 登録日 | 2018-03-23 | 公開日 | 2018-09-12 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo-EM of full-length alpha-synuclein reveals fibril polymorphs with a common structural kernel. Nat Commun, 9, 2018
|
|
6D08
| Crystal structure of an engineered bump-hole complex of mutant human chromobox homolog 1 (CBX1) with H3K9bn peptide | 分子名称: | Chromobox protein homolog 1, GLYCEROL, Histone H3.1, ... | 著者 | Arora, S, Horne, W.S, Islam, K. | 登録日 | 2018-04-10 | 公開日 | 2019-04-10 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Engineering Methyllysine Writers and Readers for Allele-Specific Regulation of Protein-Protein Interactions. J.Am.Chem.Soc., 141, 2019
|
|
6CU8
| Alpha Synuclein fibril formed by full length protein - Twister Polymorph | 分子名称: | Alpha-synuclein | 著者 | Li, B, Hatami, A, Ge, P, Murray, K.A, Sheth, P, Zhang, M, Nair, G, Sawaya, M.R, Zhu, C, Broad, M, Shin, W.S, Ye, S, John, V, Eisenberg, D.S, Zhou, Z.H, Jiang, L. | 登録日 | 2018-03-23 | 公開日 | 2018-09-12 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Cryo-EM of full-length alpha-synuclein reveals fibril polymorphs with a common structural kernel. Nat Commun, 9, 2018
|
|
6D07
| |
3OY3
| Crystal structure of ABL T315I mutant kinase domain bound with a DFG-out inhibitor AP24589 | 分子名称: | 5-[(5-{[4-{[4-(2-hydroxyethyl)piperazin-1-yl]methyl}-3-(trifluoromethyl)phenyl]carbamoyl}-2-methylphenyl)ethynyl]-1-methyl-1H-imidazole-2-carboxamide, Tyrosine-protein kinase ABL1 | 著者 | Zhou, T, Commodore, L, Huang, W.S, Wang, Y, Thomas, M, Keats, J, Xu, Q, Rivera, V, Shakespeare, W.C, Clackson, T, Dalgarno, D.C, Zhu, X. | 登録日 | 2010-09-22 | 公開日 | 2010-12-15 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural Mechanism of the Pan-BCR-ABL Inhibitor Ponatinib (AP24534): Lessons for Overcoming Kinase Inhibitor Resistance. Chem.Biol.Drug Des., 77, 2011
|
|
2PP3
| Crystal structure of L-talarate/galactarate dehydratase mutant K197A liganded with Mg and L-glucarate | 分子名称: | L-GLUCARIC ACID, L-talarate/galactarate dehydratase, MAGNESIUM ION | 著者 | Fedorov, A.A, Fedorov, E.V, Yew, W.S, Gerlt, J.A, Almo, S.C. | 登録日 | 2007-04-27 | 公開日 | 2007-08-07 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Evolution of enzymatic activities in the enolase superfamily: L-talarate/galactarate dehydratase from Salmonella typhimurium LT2. Biochemistry, 46, 2007
|
|
6H2B
| Structure of the Macrobrachium rosenbergii Nodavirus | 分子名称: | CALCIUM ION, Capsid protein | 著者 | Ho, K.H, Gabrielsen, M, Beh, P.L, Kueh, C.L, Thong, Q.X, Streetley, J, Tan, W.S, Bhella, D. | 登録日 | 2018-07-13 | 公開日 | 2018-10-31 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | 主引用文献 | Structure of the Macrobrachium rosenbergii nodavirus: A new genus within the Nodaviridae? PLoS Biol., 16, 2018
|
|
2PP1
| Crystal structure of L-talarate/galactarate dehydratase from Salmonella typhimurium LT2 liganded with Mg and L-lyxarohydroxamate | 分子名称: | (2R,3S,4R)-2,3,4-TRIHYDROXY-5-(HYDROXYAMINO)-5-OXOPENTANOIC ACID, L-talarate/galactarate dehydratase, MAGNESIUM ION | 著者 | Fedorov, A.A, Fedorov, E.V, Yew, W.S, Gerlt, J.A, Almo, S.C. | 登録日 | 2007-04-27 | 公開日 | 2007-08-07 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Evolution of enzymatic activities in the enolase superfamily: L-talarate/galactarate dehydratase from Salmonella typhimurium LT2. Biochemistry, 46, 2007
|
|
3OXZ
| Crystal structure of ABL kinase domain bound with a DFG-out inhibitor AP24534 | 分子名称: | 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide, Tyrosine-protein kinase ABL1 | 著者 | Zhou, T, Huang, W.S, Wang, Y, Thomas, M, Keats, J, Xu, Q, Rivera, V, Shakespeare, W.C, Clackson, T, Dalgarno, D.C, Zhu, X. | 登録日 | 2010-09-22 | 公開日 | 2010-12-15 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural Mechanism of the Pan-BCR-ABL Inhibitor Ponatinib (AP24534): Lessons for Overcoming Kinase Inhibitor Resistance. Chem.Biol.Drug Des., 77, 2011
|
|
2PP0
| Crystal structure of L-talarate/galactarate dehydratase from Salmonella typhimurium LT2 | 分子名称: | GLYCEROL, L-talarate/Galactarate Dehydratase | 著者 | Fedorov, A.A, Fedorov, E.V, Yew, W.S, Gerlt, J.A, Almo, S.C. | 登録日 | 2007-04-27 | 公開日 | 2007-08-07 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Evolution of enzymatic activities in the enolase superfamily: L-talarate/galactarate dehydratase from Salmonella typhimurium LT2. Biochemistry, 46, 2007
|
|
6D9F
| Protein 60 with aldehyde deformylating oxidase activity from Kitasatospora setae | 分子名称: | 1,2-ETHANEDIOL, FE (III) ION, Putative VlmB homolog, ... | 著者 | Arenas, R, Wilson, D.K, Mak, W.S, Siegel, J.B. | 登録日 | 2018-04-28 | 公開日 | 2019-05-08 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Discovery, Design, and Structural Characterization of Alkane-Producing Enzymes across the Ferritin-like Superfamily. Biochemistry, 59, 2020
|
|
2QIJ
| Hepatitis B Capsid Protein with an N-terminal extension modelled into 8.9 A data. | 分子名称: | Core antigen | 著者 | Tan, W.S, McNae, I.W, Ho, K.L, Walkinshaw, M.D. | 登録日 | 2007-07-04 | 公開日 | 2007-12-11 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (8.9 Å) | 主引用文献 | Crystallization and X-ray analysis of the T = 4 particle of hepatitis B capsid protein with an N-terminal extension. Acta Crystallogr.,Sect.F, 63, 2007
|
|
6E5K
| Heterogeneous-Backbone Mimics of a Designed Disulfide-Rich Protein: Aib turn, Aib helix, N-methyl hairpin | 分子名称: | Designed peptide NC_HEE_D1: Aib turn, Aib helix, N-methyl hairpin mutant | 著者 | Cabalteja, C.C, Mihalko, D.S, Horne, W.S. | 登録日 | 2018-07-20 | 公開日 | 2018-11-21 | 最終更新日 | 2020-01-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Heterogeneous-Backbone Foldamer Mimics of a Computationally Designed, Disulfide-Rich Miniprotein. Chembiochem, 20, 2019
|
|
6E5I
| |
6E5J
| Heterogeneous-Backbone Mimics of a Designed Disulfide-Rich Protein: Aib turn, beta3 helix, N-methyl hairpin | 分子名称: | Designed peptide NC_HEE_D1: Aib turn, beta3 helix, N-methyl hairpin mutant | 著者 | Cabalteja, C.C, Mihalko, D.S, Horne, W.S. | 登録日 | 2018-07-20 | 公開日 | 2018-11-21 | 最終更新日 | 2023-11-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Heterogeneous-Backbone Foldamer Mimics of a Computationally Designed, Disulfide-Rich Miniprotein. Chembiochem, 20, 2019
|
|
6E5H
| |
6IRP
| |