1XXB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xxb by Molmil](/molmil-images/mine/1xxb) | C-TERMINAL DOMAIN OF ESCHERICHIA COLI ARGININE REPRESSOR/ L-ARGININE COMPLEX | Descriptor: | ARGININE, ARGININE REPRESSOR | Authors: | Van Duyne, G.D, Ghosh, G, Maas, W.K, Sigler, P.B. | Deposit date: | 1995-11-03 | Release date: | 1996-03-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of the oligomerization and L-arginine binding domain of the arginine repressor of Escherichia coli. J.Mol.Biol., 256, 1996
|
|
1XXC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xxc by Molmil](/molmil-images/mine/1xxc) | |
1XXA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xxa by Molmil](/molmil-images/mine/1xxa) | C-TERMINAL DOMAIN OF ESCHERICHIA COLI ARGININE REPRESSOR/ L-ARGININE COMPLEX; PB DERIVATIVE | Descriptor: | ARGININE, ARGININE REPRESSOR, LEAD (II) ION | Authors: | Van Duyne, G.D, Ghosh, G, Maas, W.K, Sigler, P.B. | Deposit date: | 1995-11-03 | Release date: | 1996-03-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of the oligomerization and L-arginine binding domain of the arginine repressor of Escherichia coli. J.Mol.Biol., 256, 1996
|
|
1FKB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1fkb by Molmil](/molmil-images/mine/1fkb) | ATOMIC STRUCTURE OF THE RAPAMYCIN HUMAN IMMUNOPHILIN FKBP-12 COMPLEX | Descriptor: | FK506 BINDING PROTEIN, RAPAMYCIN IMMUNOSUPPRESSANT DRUG | Authors: | Van Duyne, G.D, Standaert, R.F, Schreiber, S.L, Clardy, J.C. | Deposit date: | 1992-07-02 | Release date: | 1993-10-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Atomic Structure of the Rapamycin Human Immunophilin Fkbp-12 Complex J.Am.Chem.Soc., 113, 1991
|
|
5CRX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5crx by Molmil](/molmil-images/mine/5crx) | |
4RG5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4rg5 by Molmil](/molmil-images/mine/4rg5) | Crystal Structure of S. Pombe SMN YG-Dimer | Descriptor: | MALONATE ION, Maltose-binding periplasmic protein, Survival Motor Neuron protein chimera, ... | Authors: | Gupta, K, Martin, R.S, Sarachan, K.L, Sharp, B, Van Duyne, G.D. | Deposit date: | 2014-09-29 | Release date: | 2015-07-01 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Oligomeric Properties of Survival Motor NeuronGemin2 Complexes. J.Biol.Chem., 290, 2015
|
|
4CRX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4crx by Molmil](/molmil-images/mine/4crx) | |
6DNW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6dnw by Molmil](/molmil-images/mine/6dnw) | Sequence Requirements of the Listeria innocua prophage attP site | Descriptor: | DNA (26-MER), Putative integrase [Bacteriophage A118], ZINC ION | Authors: | Li, H, Sharp, R, Rutherford, K, Gupta, K, Van Duyne, G.D. | Deposit date: | 2018-06-08 | Release date: | 2018-10-03 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.849 Å) | Cite: | Serine Integrase attP Binding and Specificity. J. Mol. Biol., 430, 2018
|
|
5E6F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5e6f by Molmil](/molmil-images/mine/5e6f) | Canarypox virus resolvase | Descriptor: | CNPV261 Holliday junction resolvase protein, D(-)-TARTARIC ACID, MAGNESIUM ION | Authors: | Li, H, Hwang, Y, Perry, K, Bushman, F.D, Van Duyne, G.D. | Deposit date: | 2015-10-09 | Release date: | 2016-03-30 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure and Metal Binding Properties of a Poxvirus Resolvase. J.Biol.Chem., 291, 2016
|
|
5U96
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5u96 by Molmil](/molmil-images/mine/5u96) | |
5UAE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5uae by Molmil](/molmil-images/mine/5uae) | Crystal structure of the coiled-coil domain from Listeria Innocua Phage Integrase (Trigonal Form) | Descriptor: | CITRATE ANION, Putative integrase | Authors: | Gupta, K, Sharp, R, Yuan, J.B, Van Duyne, G.D. | Deposit date: | 2016-12-19 | Release date: | 2017-05-24 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Coiled-coil interactions mediate serine integrase directionality. Nucleic Acids Res., 45, 2017
|
|
5UDO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5udo by Molmil](/molmil-images/mine/5udo) | |
5HOT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5hot by Molmil](/molmil-images/mine/5hot) | Structural Basis for Inhibitor-Induced Aggregation of HIV-1 Integrase | Descriptor: | (2S)-tert-butoxy[4-(8-fluoro-5-methyl-3,4-dihydro-2H-chromen-6-yl)-2-methyl-1-oxo-1,2-dihydroisoquinolin-3-yl]ethanoic acid, Integrase | Authors: | Gupta, K, Turkki, V, Sherrill-Mix, S, Hwang, Y, Eilers, G, Taylor, L, McDanal, C, Wang, P, Temelkoff, D, Nolte, R, Velthuisen, E, Jeffrey, J, Van Duyne, G.D, Bushman, F.D. | Deposit date: | 2016-01-19 | Release date: | 2016-12-14 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (4.4 Å) | Cite: | Structural Basis for Inhibitor-Induced Aggregation of HIV Integrase. PLoS Biol., 14, 2016
|
|
4KIS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4kis by Molmil](/molmil-images/mine/4kis) | Crystal Structure of a LSR-DNA Complex | Descriptor: | CALCIUM ION, DNA (26-MER), Putative integrase [Bacteriophage A118], ... | Authors: | Rutherford, K, Yuan, P, Perry, K, Van Duyne, G.D. | Deposit date: | 2013-05-02 | Release date: | 2013-07-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Attachment site recognition and regulation of directionality by the serine integrases. Nucleic Acids Res., 41, 2013
|
|
1P27
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1p27 by Molmil](/molmil-images/mine/1p27) | Crystal Structure of the Human Y14/Magoh complex | Descriptor: | Mago nashi protein homolog, RNA-binding protein 8A | Authors: | Lau, C.K, Diem, M.D, Dreyfuss, G, Van Duyne, G.D. | Deposit date: | 2003-04-14 | Release date: | 2003-08-19 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of the y14-magoh core of the exon junction complex. Curr.Biol., 13, 2003
|
|
3MGV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3mgv by Molmil](/molmil-images/mine/3mgv) | Cre recombinase-DNA transition state | Descriptor: | DNA (5'-D(*CP*AP*TP*AP*TP*GP*CP*TP*AP*TP*AP*CP*GP*AP*AP*GP*TP*TP*AP*T)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*CP*TP*TP*CP*GP*TP*AP*TP*AP*G)-3'), Recombinase cre, ... | Authors: | Gibb, B.P, Gupta, K, Ghosh, K, Sharp, R, Chen, J, Van Duyne, G.D. | Deposit date: | 2010-04-07 | Release date: | 2010-05-26 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Requirements for catalysis in the Cre recombinase active site. Nucleic Acids Res., 38, 2010
|
|
1Y96
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1y96 by Molmil](/molmil-images/mine/1y96) | crystal structure of the Gemin6/Gemin7 heterodimer from the human SMN complex | Descriptor: | Gem-associated protein 6, Gem-associated protein 7 | Authors: | Ma, Y, Dostie, J, Dreyfuss, G, Van Duyne, G.D. | Deposit date: | 2004-12-14 | Release date: | 2005-06-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.002 Å) | Cite: | The Gemin6-Gemin7 Heterodimer from the Survival of Motor Neurons Complex Has an Sm Protein-like Structure. Structure, 13, 2005
|
|
1XO0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xo0 by Molmil](/molmil-images/mine/1xo0) | High resolution structure of the holliday junction intermediate in cre-loxp site-specific recombination | Descriptor: | Recombinase CRE, loxP | Authors: | Ghosh, K, Lau, C.K, Guo, F, Segall, A.M, Van Duyne, G.D. | Deposit date: | 2004-10-05 | Release date: | 2004-12-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Peptide trapping of the Holliday junction intermediate in Cre-loxP site-specific recombination. J.Biol.Chem., 280, 2005
|
|
3IGC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3igc by Molmil](/molmil-images/mine/3igc) | Smallpox virus topoisomerase-DNA transition state | Descriptor: | 5'-D(*AP*TP*TP*CP*C)-3', 5'-D(*CP*GP*GP*AP*AP*TP*AP*AP*GP*GP*GP*CP*GP*AP*CP*A)-3', 5'-D(*GP*TP*GP*TP*CP*GP*CP*CP*CP*TP*T)-3', ... | Authors: | Perry, K, Hwang, Y, Bushman, F.D, Van Duyne, G.D. | Deposit date: | 2009-07-27 | Release date: | 2010-03-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Insights from the Structure of a Smallpox Virus Topoisomerase-DNA Transition State Mimic. Structure, 18, 2010
|
|
4GLI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4gli by Molmil](/molmil-images/mine/4gli) | Crystal Structure of Human SMN YG-Dimer | Descriptor: | Maltose-binding periplasmic protein, Survival motor neuron protein chimera | Authors: | Martin, R.S, Perry, K, Van Duyne, G.D. | Deposit date: | 2012-08-14 | Release date: | 2012-10-17 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.903 Å) | Cite: | The survival motor neuron protein forms soluble glycine zipper oligomers. Structure, 20, 2012
|
|
1XNS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xns by Molmil](/molmil-images/mine/1xns) | Peptide trapped Holliday junction intermediate in Cre-loxP recombination | Descriptor: | Recombinase CRE, loxP DNA | Authors: | Ghosh, K, Lau, C.K, Guo, F, Segall, A.M, Van Duyne, G.D. | Deposit date: | 2004-10-05 | Release date: | 2004-12-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Peptide trapping of the Holliday junction intermediate in Cre-loxP site-specific recombination. J.Biol.Chem., 280, 2005
|
|
3C28
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3c28 by Molmil](/molmil-images/mine/3c28) | |
3BVP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3bvp by Molmil](/molmil-images/mine/3bvp) | |
3C29
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3c29 by Molmil](/molmil-images/mine/3c29) | Cre-loxP Synaptic structure | Descriptor: | LoxP DNA, chain C,, chain D,F, ... | Authors: | Ghosh, K, Van Duyne, G.D. | Deposit date: | 2008-01-24 | Release date: | 2009-02-17 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Synapsis study in detail To be Published
|
|
2H7F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2h7f by Molmil](/molmil-images/mine/2h7f) | Structure of variola topoisomerase covalently bound to DNA | Descriptor: | 5'-D(*TP*AP*AP*TP*AP*AP*GP*GP*GP*CP*GP*AP*CP*A)-3', 5'-D(*TP*TP*GP*TP*CP*GP*CP*CP*CP*TP*T)-3', DNA topoisomerase 1 | Authors: | Perry, K, Hwang, Y, Bushman, F.D, Van Duyne, G.D. | Deposit date: | 2006-06-02 | Release date: | 2006-08-15 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis for specificity in the poxvirus topoisomerase. Mol.Cell, 23, 2006
|
|