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8HHM
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BU of 8hhm by Molmil
Cryo-EM structure of the Cas12m2-crRNA-target DNA ternary complex intermediate state
Descriptor: Cas12m2, DNA (36-MER), GUANOSINE-5'-MONOPHOSPHATE, ...
Authors:Omura, N.S, Nakagawa, R, Wu, Y.W, Sudfeld, C, Warren, V.R, Hirano, H, Kusakizako, T, Kise, Y, Lebbink, H.G.J, Itoh, Y, Oost, V.D.J, Nureki, O.
Deposit date:2022-11-16
Release date:2023-04-12
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:Mechanistic and evolutionary insights into a type V-M CRISPR-Cas effector enzyme.
Nat.Struct.Mol.Biol., 30, 2023
8HIO
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BU of 8hio by Molmil
Cryo-EM structure of the Cas12m2-crRNA binary complex
Descriptor: Cas12m2, MAGNESIUM ION, RNA (56-MER), ...
Authors:Omura, N.S, Nakagawa, R, Wu, Y.W, Sudfeld, C, Warren, V.R, Hirano, H, Kusakizako, T, Kise, Y, Lebbink, H.G.J, Itoh, Y, Oost, V.D.J, Nureki, O.
Deposit date:2022-11-21
Release date:2023-04-12
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (3.73 Å)
Cite:Mechanistic and evolutionary insights into a type V-M CRISPR-Cas effector enzyme.
Nat.Struct.Mol.Biol., 30, 2023
8HHL
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BU of 8hhl by Molmil
Cryo-EM structure of the Cas12m2-crRNA-target DNA full R-loop complex
Descriptor: Cas12m2, MAGNESIUM ION, NTS (36-MER), ...
Authors:Omura, N.S, Nakagawa, R, Wu, Y.W, Sudfeld, C, Warren, V.R, Hirano, H, Kusakizako, T, Kise, Y, Lebbink, H.G.J, Itoh, Y, Oost, V.D.J, Nureki, O.
Deposit date:2022-11-16
Release date:2023-04-12
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (2.87 Å)
Cite:Mechanistic and evolutionary insights into a type V-M CRISPR-Cas effector enzyme.
Nat.Struct.Mol.Biol., 30, 2023
8TL0
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BU of 8tl0 by Molmil
Structure of activated SAVED-CHAT filament
Descriptor: CHAT domain-containing protein, RNA (5'-R(*AP*AP*A)-3')
Authors:Bravo, J.P.K, Taylor, D.W.
Deposit date:2023-07-26
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Type III-B CRISPR-Cas cascade of proteolytic cleavages.
Science, 383, 2024
8H1J
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BU of 8h1j by Molmil
Cryo-EM structure of the TnpB-omegaRNA-target DNA ternary complex
Descriptor: Non-target strand, RNA-guided DNA endonuclease TnpB, Target strand, ...
Authors:Nakagawa, R, Hirano, H, Omura, S, Nureki, O.
Deposit date:2022-10-03
Release date:2023-04-12
Last modified:2023-04-26
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM structure of the transposon-associated TnpB enzyme.
Nature, 616, 2023
1CYX
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BU of 1cyx by Molmil
QUINOL OXIDASE (PERIPLASMIC FRAGMENT OF SUBUNIT II WITH ENGINEERED CU-A BINDING SITE)(CYOA)
Descriptor: CYOA, DINUCLEAR COPPER ION
Authors:Wilmanns, M, Lappalainen, P, Kelly, M, Sauer-Eriksson, E, Saraste, M.
Deposit date:1995-08-22
Release date:1996-03-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the membrane-exposed domain from a respiratory quinol oxidase complex with an engineered dinuclear copper center.
Proc.Natl.Acad.Sci.USA, 92, 1995
3BQB
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BU of 3bqb by Molmil
Hexagonal kristal form of 2-keto-3-deoxyarabinonate dehydratase
Descriptor: MAGNESIUM ION, Putative uncharacterized protein
Authors:Barends, T.M, Brouns, S, Worm, P, Akerboom, J, Turnbull, A, Salmon, L.
Deposit date:2007-12-20
Release date:2008-04-08
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural insight into substrate binding and catalysis of a novel 2-keto-3-deoxy-D-arabinonate dehydratase illustrates common mechanistic features of the FAH superfamily
J.Mol.Biol., 379, 2008
2MEZ
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BU of 2mez by Molmil
Flexible anchoring of archaeal MBF1 on ribosomes suggests role as recruitment factor
Descriptor: Multiprotein Bridging Factor (MBP-like)
Authors:Launay, H, Blombarch, F, Camilloni, C, Vendruscolo, M, van des Oost, J, Christodoulou, J.
Deposit date:2013-10-03
Release date:2014-06-25
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Archaeal MBF1 binds to 30S and 70S ribosomes via its helix-turn-helix domain.
Biochem.J., 462, 2014
2NUY
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BU of 2nuy by Molmil
2-keto-3-deoxygluconate aldolase from Sulfolobus acidocaldarius in complex with pyruvate
Descriptor: 2-keto-3-deoxygluconate/2-keto-3-deoxy-6-phospho gluconate aldolase, MAGNESIUM ION, PYRUVIC ACID
Authors:van Eerde, A, Dijkstra, B.W.
Deposit date:2006-11-10
Release date:2007-04-10
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Biochemical and structural exploration of the catalytic capacity of Sulfolobus KDG aldolases
Biochem.J., 403, 2007
2NUX
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BU of 2nux by Molmil
2-keto-3-deoxygluconate aldolase from Sulfolobus acidocaldarius, native structure in p6522 at 2.5 A resolution
Descriptor: 2-keto-3-deoxygluconate/2-keto-3-deoxy-6-phospho gluconate aldolase, MAGNESIUM ION
Authors:van Eerde, A, Dijkstra, B.W.
Deposit date:2006-11-10
Release date:2007-04-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Biochemical and structural exploration of the catalytic capacity of Sulfolobus KDG aldolases
Biochem.J., 403, 2007
2NUW
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BU of 2nuw by Molmil
2-keto-3-deoxygluconate aldolase from Sulfolobus acidocaldarius, native structure at 1.8 A resolution
Descriptor: 2-keto-3-deoxygluconate/2-keto-3-deoxy-6-phospho gluconate aldolase, MAGNESIUM ION
Authors:van Eerde, A, Dijkstra, B.W.
Deposit date:2006-11-10
Release date:2007-04-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Biochemical and structural exploration of the catalytic capacity of Sulfolobus KDG aldolases
Biochem.J., 403, 2007
4KPY
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BU of 4kpy by Molmil
DNA binding protein and DNA complex structure
Descriptor: DNA (5'-D(*TP*AP*TP*AP*CP*AP*AP*CP*C)-3'), DNA (5'-D(P*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3'), DNA (5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3'), ...
Authors:Sheng, G, Zhao, H, Wang, J, Rao, Y, Wang, Y.
Deposit date:2013-05-14
Release date:2014-01-29
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.406 Å)
Cite:Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage.
Proc.Natl.Acad.Sci.USA, 111, 2014
4N76
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BU of 4n76 by Molmil
Structure of Thermus thermophilus Argonaute bound to guide DNA and cleaved target DNA with Mn2+
Descriptor: 5'-D(P*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3', 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3', Argonaute, ...
Authors:Sheng, G, Zhao, H, Wang, J, Rao, Y, Wang, Y.
Deposit date:2013-10-15
Release date:2014-01-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage.
Proc.Natl.Acad.Sci.USA, 111, 2014
4DAP
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BU of 4dap by Molmil
The structure of Escherichia coli SfsA
Descriptor: SODIUM ION, Sugar fermentation stimulation protein A
Authors:Baker, P.J, Allen, F.L.
Deposit date:2012-01-13
Release date:2013-08-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of SfsA and its DNA complex; A DNA/RNA nuclease with a novel domain combination
To be Published
4DAV
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BU of 4dav by Molmil
The structure of Pyrococcus Furiosus SfsA in complex with DNA
Descriptor: 5'-D(*CP*GP*CP*TP*GP*TP*CP*TP*CP*GP*CP*T)-3', Sugar fermentation stimulation protein homolog
Authors:Baker, P.J, Allen, F.L.
Deposit date:2012-01-13
Release date:2014-10-01
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of SfsA and its DNA complex; A DNA/RNA nuclease with a novel domain combination
To be Published
4DA2
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BU of 4da2 by Molmil
The structure of Pyrococcus Furiosus SfsA in complex with Ca2+
Descriptor: CALCIUM ION, Sugar fermentation stimulation protein homolog
Authors:Baker, P.J, Allen, F.L.
Deposit date:2012-01-12
Release date:2014-10-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structure of SfsA and its DNA complex; A DNA/RNA nuclease with a novel domain combination
To be Published
4LUM
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BU of 4lum by Molmil
The crystal structure of the P132V mutant of Pyrococcus furiosus phosphoglucose isomerase in complex with manganese and fructose-6- phosphate.
Descriptor: FRUCTOSE -6-PHOSPHATE, Glucose-6-phosphate isomerase, MANGANESE (II) ION
Authors:Baker, P.J, Almourfi, F.M.
Deposit date:2013-07-25
Release date:2014-07-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Correlated mutation analysis as a tool for smart library design to improve protein performance.
To be Published
4LUK
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BU of 4luk by Molmil
The crystal structure of the P132A, Y133G mutant of Pyrococcus furiosus phosphoglucose isomerase in complex with manganese and 5-phospho-D-arabinonate.
Descriptor: 1,2-ETHANEDIOL, 5-PHOSPHOARABINONIC ACID, Glucose-6-phosphate isomerase, ...
Authors:Baker, P.J, Almourfi, F.M.
Deposit date:2013-07-25
Release date:2014-07-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Correlated mutation analysis as a tool for smart library design to improve protein performance.
To be Published
4LUL
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BU of 4lul by Molmil
The crystal structure of the P132A, Y133D mutant of Pyrococcus furiosus phosphoglucose isomerase in complex with manganese.
Descriptor: Glucose-6-phosphate isomerase, MANGANESE (II) ION
Authors:Baker, P.J, Almourfi, F.M.
Deposit date:2013-07-25
Release date:2014-07-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Correlated mutation analysis as a tool for smart library design to improve protein performance.
To be Published
4LTA
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BU of 4lta by Molmil
The crystal structure of the P132R, Y133G mutant of Pyrococcus furiosus phosphoglucose isomerase in complex with manganese and 5-phospho-D-arabinonate.
Descriptor: 1,2-ETHANEDIOL, 5-PHOSPHOARABINONIC ACID, Glucose-6-phosphate isomerase, ...
Authors:Baker, P.J, Almourfi, F.M.
Deposit date:2013-07-23
Release date:2014-07-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Correlated mutation analysis as a tool for smart library design to improve protein performance.
To be Published
1CYW
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BU of 1cyw by Molmil
QUINOL OXIDASE (PERIPLASMIC FRAGMENT OF SUBUNIT II) (CYOA)
Descriptor: CYOA
Authors:Wilmanns, M, Lappalainen, P, Kelly, M, Sauer-Eriksson, E, Saraste, M.
Deposit date:1995-08-22
Release date:1996-03-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the membrane-exposed domain from a respiratory quinol oxidase complex with an engineered dinuclear copper center.
Proc.Natl.Acad.Sci.USA, 92, 1995
4N41
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BU of 4n41 by Molmil
Structure of Thermus thermophilus Argonaute bound to guide DNA and 15-mer target DNA
Descriptor: 5'-D(*AP*AP*CP*CP*TP*AP*CP*TP*GP*CP*CP*TP*CP*G)-3', 5'-D(P*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3', 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*T*GP*TP*AP*TP*AP*GP*T)-3', ...
Authors:Sheng, G, Zhao, H, Wang, J, Rao, Y, Wang, Y.
Deposit date:2013-10-08
Release date:2014-01-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.248 Å)
Cite:Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage.
Proc.Natl.Acad.Sci.USA, 111, 2014
4N47
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BU of 4n47 by Molmil
Structure of Thermus thermophilus Argonaute bound to guide DNA and 12-mer target DNA
Descriptor: 5'-D(*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3', 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3', Argonaute, ...
Authors:Sheng, G, Zhao, H, Wang, J, Rao, Y, Wang, Y.
Deposit date:2013-10-08
Release date:2014-01-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.823 Å)
Cite:Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage.
Proc.Natl.Acad.Sci.USA, 111, 2014
4NCA
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BU of 4nca by Molmil
Structure of Thermus thermophilus Argonaute bound to guide DNA 19-mer and target DNA in the presence of Mg2+
Descriptor: 5'-D(*AP*CP*AP*AP*CP*C)-3', 5'-D(P*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3', 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3', ...
Authors:Sheng, G, Zhao, H, Wang, J, Rao, Y, Wang, Y.
Deposit date:2013-10-24
Release date:2014-01-15
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (2.489 Å)
Cite:Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage.
Proc.Natl.Acad.Sci.USA, 111, 2014
4NCB
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BU of 4ncb by Molmil
Structure of Thermus thermophilus Argonaute bound to guide DNA and 19-mer target DNA with Mg2+
Descriptor: 5'-D(*TP*AP*TP*AP*CP*AP*AP*CP*C)-3', 5'-D(*TP*AP*TP*AP*CP*AP*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3', 5'-D(P*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3', ...
Authors:Sheng, G, Zhao, H, Wang, J, Rao, Y, Wang, Y.
Deposit date:2013-10-24
Release date:2014-01-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.189 Å)
Cite:Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage.
Proc.Natl.Acad.Sci.USA, 111, 2014

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