3DWA
 
 | | Crystal structure of the B-subunit of the AB5 toxin from E. coli | | 分子名称: | PENTAETHYLENE GLYCOL, Subtilase cytotoxin, subunit B | | 著者 | Byres, E, Paton, A.W, Paton, J.C, Lofling, J.C, Smith, D.F, Wilce, M.C.J, Talbot, U.M, Chong, D.C, Yu, H, Huang, S, Chen, X, Varki, N.M, Varki, A, Rossjohn, J, Beddoe, T. | | 登録日 | 2008-07-22 | | 公開日 | 2008-11-04 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.084 Å) | | 主引用文献 | Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin
Nature, 456, 2008
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3DWP
 | | Crystal structure of the B-subunit of the AB5 toxin from E. Coli with Neu5Gc | | 分子名称: | N-glycolyl-alpha-neuraminic acid, PENTAETHYLENE GLYCOL, Subtilase cytotoxin, ... | | 著者 | Byres, E, Paton, A.W, Paton, J.C, Lofling, J.C, Smith, D.F, Wilce, M.C.J, Talbot, U.M, Chong, D.C, Yu, H, Huang, S, Chen, X, Varki, N.M, Varki, A, Rossjohn, J, Beddoe, T. | | 登録日 | 2008-07-22 | | 公開日 | 2008-11-04 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin
Nature, 456, 2008
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3DWQ
 | | Crystal structure of the A-subunit of the AB5 toxin from E. coli with Neu5Gc-2,3Gal-1,3GlcNAc | | 分子名称: | AZIDE ION, N-PROPANOL, N-glycolyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, ... | | 著者 | Byres, E, Paton, A.W, Paton, J.C, Lofling, J.C, Smith, D.F, Wilce, M.C.J, Talbot, U.M, Chong, D.C, Yu, H, Huang, S, Chen, X, Varki, N.M, Varki, A, Rossjohn, J, Beddoe, T. | | 登録日 | 2008-07-22 | | 公開日 | 2008-11-04 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin
Nature, 456, 2008
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5WAH
 | | SOLUTION NMR STRUCTURE OF SIGLEC-5 BINDING DOMAIN FROM STREPTOCOCCAL BETA PROTEIN | | 分子名称: | IgA FC receptor | | 著者 | ELETSKY, A, CHEN, C, FONG, J.J, NIZET, V, VARKI, A, PRESTEGARD, J.H. | | 登録日 | 2017-06-26 | | 公開日 | 2018-06-27 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | SOLUTION NMR STRUCTURE OF SIGLEC-5 BINDING DOMAIN FROM STREPTOCOCCAL BETA PROTEIN
To Be Published
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6MRV
 | | Sialidase26 co-crystallized with DANA | | 分子名称: | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, Sialidase26 | | 著者 | Zaramela, L.S, Martino, C, Alisson-Silva, F, Rees, S.D, Diaz, S.L, Chuzel, L, Ganatra, M.B, Taron, C.H, Zuniga, C, Chang, G, Varki, A, Zengler, K. | | 登録日 | 2018-10-15 | | 公開日 | 2019-10-02 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Gut bacteria responding to dietary change encode sialidases that exhibit preference for red meat-associated carbohydrates.
Nat Microbiol, 4, 2019
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6MRX
 | | Sialidase26 apo | | 分子名称: | Sialidase26 | | 著者 | Zaramela, L.S, Martino, C, Alisson-Silva, F, Rees, S.D, Diaz, S.L, Chuzel, L, Ganatra, M.B, Taron, C.H, Zuniga, C, Chang, G, Varki, A, Zengler, K. | | 登録日 | 2018-10-15 | | 公開日 | 2019-10-02 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Gut bacteria responding to dietary change encode sialidases that exhibit preference for red meat-associated carbohydrates.
Nat Microbiol, 4, 2019
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6MYV
 | | Sialidase26 co-crystallized with DANA-Gc | | 分子名称: | 2,6-anhydro-3,5-dideoxy-5-[(hydroxyacetyl)amino]-D-glycero-L-altro-non-2-enonic acid, Sialidase26 | | 著者 | Zaramela, L.S, Martino, C, Alisson-Silva, F, Rees, S.D, Diaz, S.L, Chuzel, L, Ganatra, M.B, Taron, C.H, Zuniga, C, Huang, J, Siegel, D, Chang, G, Varki, A, Zengler, K. | | 登録日 | 2018-11-02 | | 公開日 | 2019-10-02 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Gut bacteria responding to dietary change encode sialidases that exhibit preference for red meat-associated carbohydrates.
Nat Microbiol, 4, 2019
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4RHR
 | | Crystal structure of PltB | | 分子名称: | ACETATE ION, Putative pertussis-like toxin subunit | | 著者 | Gao, X, Wang, J, Galan, J. | | 登録日 | 2014-10-02 | | 公開日 | 2014-10-29 | | 最終更新日 | 2014-12-17 | | 実験手法 | X-RAY DIFFRACTION (2.079 Å) | | 主引用文献 | Host adaptation of a bacterial toxin from the human pathogen salmonella typhi.
Cell(Cambridge,Mass.), 159, 2014
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4RHS
 | | Crystal structure of GD2 bound PltB | | 分子名称: | ACETATE ION, N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose, Putative pertussis-like toxin subunit | | 著者 | Gao, X, Wang, J, Galan, J. | | 登録日 | 2014-10-02 | | 公開日 | 2014-10-29 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.9211 Å) | | 主引用文献 | Host adaptation of a bacterial toxin from the human pathogen salmonella typhi.
Cell(Cambridge,Mass.), 159, 2014
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4AIU
 | | A complex structure of BtGH84 | | 分子名称: | (3AR,5R,6S,7R,7AR)-2,5-BIS(HYDROXYMETHYL)-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D][1,3]OXAZOLE-6,7-DIOL, CALCIUM ION, O-GLCNACASE BT_4395 | | 著者 | He, Y, Davies, G.J. | | 登録日 | 2012-02-13 | | 公開日 | 2012-06-20 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Metabolism of Vertebrate Amino Sugars with N-Glycolyl Groups: Intracellular Beta-O-Linked N-Glycolylglucosamine (Glcngc), Udp-Glcngc, and the Biochemical and Structural Rationale for the Substrate Tolerance of Beta-O-Linked Beta-N-Acetylglucosaminidase.
J.Biol.Chem., 287, 2012
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4AIS
 | | A complex structure of BtGH84 | | 分子名称: | GLYCEROL, GLYCOLIC ACID, O-GLCNACASE BT_4395 | | 著者 | He, Y, Davies, G.J. | | 登録日 | 2012-02-13 | | 公開日 | 2012-06-20 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Metabolism of Vertebrate Amino Sugars with N-Glycolyl Groups: Intracellular Beta-O-Linked N-Glycolylglucosamine (Glcngc), Udp-Glcngc, and the Biochemical and Structural Rationale for the Substrate Tolerance of Beta-O-Linked Beta-N-Acetylglucosaminidase.
J.Biol.Chem., 287, 2012
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6ER3
 | | Ruminococcus gnavus IT-sialidase CBM40 bound to alpha2,3 sialyllactose | | 分子名称: | BNR/Asp-box repeat protein, GLYCEROL, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose | | 著者 | Owen, C.D, Tailford, L.E, Taylor, G.L, Juge, N. | | 登録日 | 2017-10-16 | | 公開日 | 2018-05-02 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | | 主引用文献 | Unravelling the specificity and mechanism of sialic acid recognition by the gut symbiont Ruminococcus gnavus.
Nat Commun, 8, 2017
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6ER4
 | | Ruminococcus gnavus IT-sialidase CBM40 bound to alpha2,6 sialyllactose | | 分子名称: | BNR/Asp-box repeat protein, GLYCEROL, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, ... | | 著者 | Owen, C.D, Tailford, L.E, Taylor, G.L, Juge, N. | | 登録日 | 2017-10-16 | | 公開日 | 2018-05-02 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Unravelling the specificity and mechanism of sialic acid recognition by the gut symbiont Ruminococcus gnavus.
Nat Commun, 8, 2017
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6MNJ
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6ER2
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5WHV
 | | Crystal structure of ArtB | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ArtB protein, CALCIUM ION, ... | | 著者 | Gao, X, Galan, J.E. | | 登録日 | 2017-07-18 | | 公開日 | 2017-10-25 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.303 Å) | | 主引用文献 | Evolution of host adaptation in the Salmonella typhoid toxin.
Nat Microbiol, 2, 2017
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5WHT
 | | Crystal structure of 3'SL bound PltB | | 分子名称: | ACETATE ION, DI(HYDROXYETHYL)ETHER, N-acetyl-alpha-neuraminic acid, ... | | 著者 | Gao, X, Galan, J.E. | | 登録日 | 2017-07-18 | | 公開日 | 2017-10-25 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.932 Å) | | 主引用文献 | Evolution of host adaptation in the Salmonella typhoid toxin.
Nat Microbiol, 2, 2017
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5WHU
 | | Crystal structure of 3'SL bound ArtB | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ArtB protein, ... | | 著者 | Gao, X, Galan, J.E. | | 登録日 | 2017-07-18 | | 公開日 | 2017-10-25 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Evolution of host adaptation in the Salmonella typhoid toxin.
Nat Microbiol, 2, 2017
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5E62
 | | HEF-mut with Tr323 complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 9-O-acetyl-5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-azidoethyl 2-acetamido-2-deoxy-beta-D-glucopyranoside, ... | | 著者 | Song, H, Qi, J, Shi, Y, Gao, G.F. | | 登録日 | 2015-10-09 | | 公開日 | 2016-03-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.203 Å) | | 主引用文献 | An Open Receptor-Binding Cavity of Hemagglutinin-Esterase-Fusion Glycoprotein from Newly-Identified Influenza D Virus: Basis for Its Broad Cell Tropism
PLoS Pathog., 12, 2016
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5E65
 | | The complex structure of Hemagglutinin-esterase-fusion mutant protein from the influenza D virus with receptor analog 9-O-Ac-3'SLN (Tr322) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 9-O-acetyl-5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid-(2-3)-beta-D-galactopyranose, ... | | 著者 | Song, H, Qi, J, Shi, Y, Gao, G.F. | | 登録日 | 2015-10-09 | | 公開日 | 2016-03-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | An Open Receptor-Binding Cavity of Hemagglutinin-Esterase-Fusion Glycoprotein from Newly-Identified Influenza D Virus: Basis for Its Broad Cell Tropism
PLoS Pathog., 12, 2016
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5E64
 | | Hemagglutinin-esterase-fusion protein structure of influenza D virus | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CACODYLATE ION, ... | | 著者 | Song, H, Qi, J, Shi, Y, Gao, G.F. | | 登録日 | 2015-10-09 | | 公開日 | 2016-03-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | An Open Receptor-Binding Cavity of Hemagglutinin-Esterase-Fusion Glycoprotein from Newly-Identified Influenza D Virus: Basis for Its Broad Cell Tropism
PLoS Pathog., 12, 2016
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5E5W
 | | Hemagglutinin-esterase-fusion mutant structure of influenza D virus | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin-esterase, ... | | 著者 | Song, H, Qi, J, Shi, Y, Gao, G.F. | | 登録日 | 2015-10-09 | | 公開日 | 2016-03-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | An Open Receptor-Binding Cavity of Hemagglutinin-Esterase-Fusion Glycoprotein from Newly-Identified Influenza D Virus: Basis for Its Broad Cell Tropism
PLoS Pathog., 12, 2016
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5E66
 | | The complex structure of Hemagglutinin-esterase-fusion mutant protein from the influenza D virus with receptor analog 9-N-Ac-Sia | | 分子名称: | (6R)-5-acetamido-6-[(1S,2S)-3-acetamido-1,2-dihydroxypropyl]-3,5-dideoxy-beta-L-threo-hex-2-ulopyranosonic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Song, H, Qi, J, Shi, Y, Gao, G.F. | | 登録日 | 2015-10-09 | | 公開日 | 2016-03-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | An Open Receptor-Binding Cavity of Hemagglutinin-Esterase-Fusion Glycoprotein from Newly-Identified Influenza D Virus: Basis for Its Broad Cell Tropism
PLoS Pathog., 12, 2016
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