5AFR
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![BU of 5afr by Molmil](/molmil-images/mine/5afr) | N-terminal fragment of dynein heavy chain | Descriptor: | DYNEIN HEAVY CHAIN, CYTOPLASMIC | Authors: | Urnavicius, L, Zhang, K, Diamant, A.G, Motz, C, Schlager, M.A, Yu, M, Patel, N.A, Robinson, C.V, Carter, A.P. | Deposit date: | 2015-01-23 | Release date: | 2015-02-18 | Last modified: | 2018-04-25 | Method: | X-RAY DIFFRACTION (5 Å) | Cite: | The Structure of the Dynactin Complex and its Interaction with Dynein. Science, 347, 2015
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5AFU
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![BU of 5afu by Molmil](/molmil-images/mine/5afu) | Cryo-EM structure of dynein tail-dynactin-BICD2N complex | Descriptor: | ACTIN, CYTOPLASMIC 1, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Urnavicius, L, Zhang, K, Diamant, A.G, Motz, C, Schlager, M.A, Yu, M, Patel, N.A, Robinson, C.V, Carter, A.P. | Deposit date: | 2015-01-26 | Release date: | 2015-03-11 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (8.2 Å) | Cite: | The Structure of the Dynactin Complex and its Interaction with Dynein. Science, 347, 2015
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5OWO
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![BU of 5owo by Molmil](/molmil-images/mine/5owo) | Human cytoplasmic Dynein N-Terminus dimerization domain at 1.8 Angstrom resolution | Descriptor: | CALCIUM ION, Cytoplasmic dynein 1 heavy chain 1, GLYCEROL, ... | Authors: | Urnavicius, L, Lau, C.K, Elshenawy, M.M, Morales-Rios, E, Motz, C, Yildiz, A, Carter, A.P. | Deposit date: | 2017-09-01 | Release date: | 2018-07-11 | Last modified: | 2022-03-30 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Cryo-EM shows how dynactin recruits two dyneins for faster movement. Nature, 554, 2018
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6F1T
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![BU of 6f1t by Molmil](/molmil-images/mine/6f1t) | Cryo-EM structure of two dynein tail domains bound to dynactin and BICDR1 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ARP1 actin related protein 1 homolog A, ... | Authors: | Urnavicius, L, Lau, C.K, Elshenawy, M.M, Morales-Rios, E, Motz, C, Yildiz, A, Carter, A.P. | Deposit date: | 2017-11-23 | Release date: | 2018-01-17 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo-EM shows how dynactin recruits two dyneins for faster movement. Nature, 554, 2018
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6F3A
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![BU of 6f3a by Molmil](/molmil-images/mine/6f3a) | Cryo-EM structure of a single dynein tail domain bound to dynactin and BICD2N | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ARP1 actin related protein 1 homolog A, ... | Authors: | Urnavicius, L, Lau, C.K, Elshenawy, M.M, Morales-Rios, E, Motz, C, Yildiz, A, Carter, A.P. | Deposit date: | 2017-11-28 | Release date: | 2018-01-17 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (8.2 Å) | Cite: | Cryo-EM shows how dynactin recruits two dyneins for faster movement. Nature, 554, 2018
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6F1Y
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![BU of 6f1y by Molmil](/molmil-images/mine/6f1y) | Dynein light intermediate chain region of the dynein tail/dynactin/BICDR1 complex | Descriptor: | Cytoplasmic dynein 1 heavy chain 1,Dynein heavy chain, Cytoplasmic dynein 1 light intermediate chain 2 | Authors: | Urnavicius, L, Lau, C.K, Elshenawy, M.M, Morales-Rios, E, Motz, C, Yildiz, A, Carter, A.P. | Deposit date: | 2017-11-23 | Release date: | 2018-01-17 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM shows how dynactin recruits two dyneins for faster movement. Nature, 554, 2018
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6F1U
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![BU of 6f1u by Molmil](/molmil-images/mine/6f1u) | N terminal region of dynein tail domains in complex with dynactin filament and BICDR-1 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ARP1 actin related protein 1 homolog A, BICD family-like cargo adapter 1, ... | Authors: | Urnavicius, L, Lau, C.K, Elshenawy, M.M, Morales-Rios, E, Motz, C, Yildiz, A, Carter, A.P. | Deposit date: | 2017-11-23 | Release date: | 2018-01-17 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM shows how dynactin recruits two dyneins for faster movement. Nature, 554, 2018
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6F1V
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![BU of 6f1v by Molmil](/molmil-images/mine/6f1v) | C terminal region of the dynein heavy chains in the dynein tail/dynactin/BICDR1 complex | Descriptor: | Cytoplasmic dynein 1 heavy chain 1 | Authors: | Urnavicius, L, Lau, C.K, Elshenawy, M.M, Morales-Rios, E, Motz, C, Yildiz, A, Carter, A.P. | Deposit date: | 2017-11-23 | Release date: | 2018-01-17 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM shows how dynactin recruits two dyneins for faster movement. Nature, 554, 2018
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6F1Z
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![BU of 6f1z by Molmil](/molmil-images/mine/6f1z) | Roadblock-1 region of the dynein tail/dynactin/BICDR1 complex | Descriptor: | Cytoplasmic dynein 1 intermediate chain 2, Dynein light chain roadblock-type 1 | Authors: | Urnavicius, L, Lau, C.K, Elshenawy, M.M, Morales-Rios, E, Motz, C, Yildiz, A, Carter, A.P. | Deposit date: | 2017-11-23 | Release date: | 2018-01-17 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM shows how dynactin recruits two dyneins for faster movement. Nature, 554, 2018
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5ADX
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![BU of 5adx by Molmil](/molmil-images/mine/5adx) | CryoEM structure of dynactin complex at 4.0 angstrom resolution | Descriptor: | ACTIN RELATED PROTEIN 1, ACTIN RELATED PROTEIN 11, ACTIN, ... | Authors: | Zhang, K, Urnavicius, L, Diamant, A.G, Motz, C, Schlage, M.A, Yu, M, Patel, N.A, Robinson, C.V, Carter, A.P. | Deposit date: | 2015-08-24 | Release date: | 2015-12-30 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | The Structure of the Dynactin Complex and its Interaction with Dynein. Science, 347, 2015
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6F38
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![BU of 6f38 by Molmil](/molmil-images/mine/6f38) | Cryo-EM structure of two dynein tail domains bound to dynactin and HOOK3 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ARP1 actin related protein 1 homolog A, ... | Authors: | Lau, C.K, Urnavicius, L, Elshenawy, M.M, Morales-Rios, E, Motz, C, Yildiz, A, Carter, A.P. | Deposit date: | 2017-11-28 | Release date: | 2018-01-17 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (6.7 Å) | Cite: | Cryo-EM shows how dynactin recruits two dyneins for faster movement. Nature, 554, 2018
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4RH7
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![BU of 4rh7 by Molmil](/molmil-images/mine/4rh7) | Crystal structure of human cytoplasmic dynein 2 motor domain in complex with ADP.Vi | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ADP ORTHOVANADATE, ... | Authors: | Schmidt, H, Zalyte, R, Urnavicius, L, Carter, A.P. | Deposit date: | 2014-10-01 | Release date: | 2014-12-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.41 Å) | Cite: | Structure of human cytoplasmic dynein-2 primed for its power stroke. Nature, 518, 2015
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7MI8
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![BU of 7mi8 by Molmil](/molmil-images/mine/7mi8) | Signal subtracted reconstruction of AAA5 and AAA6 domains of dynein in the presence of a pyrazolo-pyrimidinone-based compound, Model 5 | Descriptor: | Fusion protein of Dynein and Endolysin | Authors: | Santarossa, C.C, Coudray, N, Urnavicius, L, Ekiert, D.C, Bhabha, G, Kapoor, T.M. | Deposit date: | 2021-04-16 | Release date: | 2021-05-26 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Targeting allostery in the Dynein motor domain with small molecule inhibitors. Cell Chem Biol, 28, 2021
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7MI6
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![BU of 7mi6 by Molmil](/molmil-images/mine/7mi6) | Yeast dynein motor domain in the presence of a pyrazolo-pyrimidinone-based compound, Model 1 | Descriptor: | (8S)-6-(3-bromophenoxy)-2-[1-(4-chlorophenyl)cyclopropyl]-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carbonitrile, ADENOSINE-5'-TRIPHOSPHATE, Fusion protein of Dynein and Endolysin, ... | Authors: | Santarossa, C.C, Urnavicius, L, Coudray, N, Ekeirt, D.C, Bhabha, G, Kapoor, T.M. | Deposit date: | 2021-04-16 | Release date: | 2021-05-26 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Targeting allostery in the Dynein motor domain with small molecule inhibitors. Cell Chem Biol, 28, 2021
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7MI3
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![BU of 7mi3 by Molmil](/molmil-images/mine/7mi3) | Signal subtracted reconstruction of AAA2, AAA3, and AAA4 domains of dynein in the presence of a pyrazolo-pyrimidinone-based compound, Model 4 | Descriptor: | (8S)-6-(3-bromophenoxy)-2-[1-(4-chlorophenyl)cyclopropyl]-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carbonitrile, ADENOSINE-5'-TRIPHOSPHATE, Fusion protein of Dynein and Endolysin, ... | Authors: | Santarossa, C.C, Coudray, N, Urnavicius, L, Ekiert, D.C, Bhabha, G, Kapoor, T.M. | Deposit date: | 2021-04-16 | Release date: | 2021-05-26 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Targeting allostery in the Dynein motor domain with small molecule inhibitors. Cell Chem Biol, 28, 2021
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6I27
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![BU of 6i27 by Molmil](/molmil-images/mine/6i27) | Rea1 AAA2L-H2alpha deletion mutant in AMPPNP State | Descriptor: | Midasin,Midasin,Midasin,Midasin,Midasin,Midasin,Midasin | Authors: | Sosnowski, P, Urnavicius, L, Boland, A, Fagiewicz, R, Busselez, J, Papai, G, Schmidt, H. | Deposit date: | 2018-10-31 | Release date: | 2018-12-12 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (7.8 Å) | Cite: | The CryoEM structure of the Saccharomyces cerevisiae ribosome maturation factor Rea1. Elife, 7, 2018
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6HYD
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![BU of 6hyd by Molmil](/molmil-images/mine/6hyd) | Rea1 Wild type ADP state (tail part) | Descriptor: | Midasin,Midasin,Midasin | Authors: | Sosnowski, P, Urnavicius, L, Boland, A, Fagiewicz, R, Busselez, J, Papai, G, Schmidt, H. | Deposit date: | 2018-10-19 | Release date: | 2018-12-12 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | The CryoEM structure of the Saccharomyces cerevisiae ribosome maturation factor Rea1. Elife, 7, 2018
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6HYP
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![BU of 6hyp by Molmil](/molmil-images/mine/6hyp) | Rea1 Wild type ADP state (AAA+ ring part) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Midasin,Midasin | Authors: | Sosnowski, P, Urnavicius, L, Boland, A, Fagiewicz, R, Busselez, J, Papai, G, Schmidt, H. | Deposit date: | 2018-10-22 | Release date: | 2018-12-12 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | The CryoEM structure of the Saccharomyces cerevisiae ribosome maturation factor Rea1. Elife, 7, 2018
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6I26
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![BU of 6i26 by Molmil](/molmil-images/mine/6i26) | Rea1 Wild type AMPPNP state | Descriptor: | Midasin,Midasin,Midasin,Midasin | Authors: | Sosnowski, P, Urnavicius, L, Boland, A, Fagiewicz, R, Busselez, J, Papai, G, Schmidt, H. | Deposit date: | 2018-10-31 | Release date: | 2018-12-12 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | The CryoEM structure of the Saccharomyces cerevisiae ribosome maturation factor Rea1. Elife, 7, 2018
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6V69
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![BU of 6v69 by Molmil](/molmil-images/mine/6v69) | Structures of GCP4 and GCP5 in the native human gamma-tubulin ring complex | Descriptor: | Gamma-tubulin complex component 4, Gamma-tubulin complex component 5 | Authors: | Wieczorek, M, Urnavicius, L, Ti, S, Molloy, K.R, Chait, B.T, Kapoor, T.M. | Deposit date: | 2019-12-04 | Release date: | 2020-01-01 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Asymmetric Molecular Architecture of the Human gamma-Tubulin Ring Complex. Cell, 180, 2020
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6V6C
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![BU of 6v6c by Molmil](/molmil-images/mine/6v6c) | Structure of GCP6 in the native human gamma-tubulin ring complex | Descriptor: | Gamma-tubulin complex component 6 | Authors: | Wieczorek, M, Urnavicius, L, Ti, S, Molloy, K.R, Chait, B.T, Kapoor, T.M. | Deposit date: | 2019-12-04 | Release date: | 2020-01-01 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Asymmetric Molecular Architecture of the Human gamma-Tubulin Ring Complex. Cell, 180, 2020
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6V6S
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![BU of 6v6s by Molmil](/molmil-images/mine/6v6s) | Structure of the native human gamma-tubulin ring complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, Gamma-tubulin complex component 2, ... | Authors: | Wieczorek, M, Urnavicius, L, Ti, S, Molloy, K.R, Chait, B.T, Kapoor, T.M. | Deposit date: | 2019-12-05 | Release date: | 2020-01-01 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Asymmetric Molecular Architecture of the Human gamma-Tubulin Ring Complex. Cell, 180, 2020
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6V5V
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![BU of 6v5v by Molmil](/molmil-images/mine/6v5v) | Structure of gamma-tubulin in the native human gamma-tubulin ring complex | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Tubulin gamma-1 chain | Authors: | Wieczorek, M, Urnavicius, L, Ti, S, Molloy, K.R, Chait, B.T, Kapoor, T.M. | Deposit date: | 2019-12-04 | Release date: | 2020-01-01 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Asymmetric Molecular Architecture of the Human gamma-Tubulin Ring Complex. Cell, 180, 2020
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6V6B
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![BU of 6v6b by Molmil](/molmil-images/mine/6v6b) | Structures of GCP2 and GCP3 in the native human gamma-tubulin ring complex | Descriptor: | Gamma-tubulin complex component 2, Gamma-tubulin complex component 3 | Authors: | Wieczorek, M, Urnavicius, L, Ti, S, Molloy, K.R, Chait, B.T, Kapoor, T.M. | Deposit date: | 2019-12-04 | Release date: | 2020-01-01 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Asymmetric Molecular Architecture of the Human gamma-Tubulin Ring Complex. Cell, 180, 2020
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6X0V
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![BU of 6x0v by Molmil](/molmil-images/mine/6x0v) | Structure of MZT2/GCP-NHD and CDK5Rap2 at position 13 of the gamma-TuRC | Descriptor: | Centrosome protein Cep215, Gamma-tubulin complex component 2, Mitotic-spindle organizing protein 2A | Authors: | Wieczorek, M, Huang, T.-L, Urnavicius, L, Hsia, K.-C, Kapoor, T.M. | Deposit date: | 2020-05-17 | Release date: | 2020-07-22 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | MZT Proteins Form Multi-Faceted Structural Modules in the gamma-Tubulin Ring Complex. Cell Rep, 31, 2020
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