6F1T

Cryo-EM structure of two dynein tail domains bound to dynactin and BICDR1

Summary for 6F1T

EMDB information4168
DescriptorARP1 actin related protein 1 homolog A, Actin, cytoplasmic 1, Actin related protein 10 homolog, ... (26 entities in total)
Functional Keywordscryo-em, complex, motor protein, dynein/dynactin/bicdr, tdr
Biological sourceMus musculus (Mouse)
More
Cellular locationCytoplasm, cytoskeleton Q6QAQ1 Q13409 O43237 Q9NP97
Total number of polymer chains45
Total molecular weight1818540.21
Authors
Urnavicius, L.,Lau, C.K.,Elshenawy, M.M.,Morales-Rios, E.,Motz, C.,Yildiz, A.,Carter, A.P. (deposition date: 2017-11-23, release date: 2018-01-17, Last modification date: 2018-02-21)
Primary citation
Urnavicius, L.,Lau, C.K.,Elshenawy, M.M.,Morales-Rios, E.,Motz, C.,Yildiz, A.,Carter, A.P.
Cryo-EM shows how dynactin recruits two dyneins for faster movement.
Nature, 554:202-206, 2018
PubMed: 29420470 (PDB entries with the same primary citation)
DOI: 10.1038/nature25462
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
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Structure validation

ClashscoreRamachandran outliersSidechain outliers90.2%0.5%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures