1SDO
| Crystal Structure of Restriction Endonuclease BstYI | 分子名称: | BstYI | 著者 | Townson, S.A, Samuelson, J.C, Vanamee, E.S, Edwards, T.A, Escalante, C.R, Xu, S.Y, Aggarwal, A.K. | 登録日 | 2004-02-13 | 公開日 | 2004-05-11 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal Structure of BstYI at 1.85 A Resolution: A Thermophilic Restriction Endonuclease with Overlapping Specificities to BamHI and BglII J.Mol.Biol., 338, 2004
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1VRR
| Crystal structure of the restriction endonuclease BstYI complex with DNA | 分子名称: | 5'-D(*TP*TP*AP*TP*AP*GP*AP*TP*CP*TP*AP*TP*AP*A)-3', BstYI | 著者 | Townson, S.A, Samuelson, J.C, Xu, S.Y, Aggarwal, A.K. | 登録日 | 2005-06-02 | 公開日 | 2005-06-07 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Implications for Switching Restriction Enzyme Specificities from the Structure of BstYI Bound to a BglII DNA Sequence. Structure, 13, 2005
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2P0J
| Structure of restriction endonuclease BstYI bound to non-cognate DNA | 分子名称: | 5'-D(*AP*TP*GP*AP*AP*TP*CP*CP*AP*TP*A)-3', 5'-D(*TP*AP*TP*GP*GP*AP*TP*TP*CP*AP*T)-3', BstYI | 著者 | Townson, S.A, Samuelson, J.C, Bao, Y, Xu, S.Y, Aggarwal, A.K. | 登録日 | 2007-02-28 | 公開日 | 2007-05-01 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | BstYI Bound to Noncognate DNA Reveals a "Hemispecific" Complex: Implications for DNA Scanning. Structure, 15, 2007
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4FAO
| Specificity and Structure of a high affinity Activin-like 1 (ALK1) signaling complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Activin receptor type-2B, Growth/differentiation factor 2, ... | 著者 | Townson, S.A, Martinez-Hackert, E, Greppi, C, Lowden, P, Sako, D, Liu, J, Ucran, J.A, Liharska, K, Underwood, K.W, Seehra, J, Kumar, R, Grinberg, A.V. | 登録日 | 2012-05-22 | 公開日 | 2012-06-20 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.357 Å) | 主引用文献 | Specificity and Structure of a High Affinity Activin Receptor-like Kinase 1 (ALK1) Signaling Complex. J.Biol.Chem., 287, 2012
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6OQA
| Crystal structure of CEP250 bound to FKBP12 in the presence of FK506-like novel natural product | 分子名称: | (3R,4E,7E,10R,11S,12R,13S,16R,17R,24aS)-11,17-dihydroxy-10,12,16-trimethyl-3-[(2R)-1-phenylbutan-2-yl]-6,9,10,11,12,13,14,15,16,17,22,23,24,24a-tetradecahydro-3H-13,17-epoxypyrido[2,1-c][1,4]oxazacyclohenicosine-1,18,19(21H)-trione, 1,2-ETHANEDIOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, ... | 著者 | Lee, S.-J, Shigdel, U.K, Townson, S.A, Verdine, G.L. | 登録日 | 2019-04-26 | 公開日 | 2020-04-29 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Genomic discovery of an evolutionarily programmed modality for small-molecule targeting of an intractable protein surface. Proc.Natl.Acad.Sci.USA, 117, 2020
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4K71
| Crystal structure of a high affinity Human Serum Albumin variant bound to the Neonatal Fc Receptor | 分子名称: | Beta-2-microglobulin, IgG receptor FcRn large subunit p51, SULFATE ION, ... | 著者 | Schmidt, M.M, Townson, S.A, Andreucci, A, Dombrowski, C, Erbe, D.V, King, B, Kovalchin, J.T, Masci, A, Murillo, A, Schirmer, E.B, Furfine, E.S, Barnes, T.M. | 登録日 | 2013-04-16 | 公開日 | 2013-10-23 | 最終更新日 | 2014-02-05 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of an HSA/FcRn complex reveals recycling by competitive mimicry of HSA ligands at a pH-dependent hydrophobic interface. Structure, 21, 2013
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1TK7
| NMR structure of WW domains (WW3-4) from Suppressor of Deltex | 分子名称: | CG4244-PB | 著者 | Fedoroff, O.Y, Avis, J.M, Golovanov, A.P, Baron, M, Townson, S.A. | 登録日 | 2004-06-08 | 公開日 | 2004-07-20 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | The structure and dynamics of tandem WW domains in a negative regulator of notch signaling, Suppressor of deltex J.Biol.Chem., 279, 2004
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2OH2
| Ternary Complex of Human DNA Polymerase | 分子名称: | 5'-D(*GP*GP*G*GP*GP*AP*AP*GP*GP*AP*CP*CP*C)-3', 5'-D(*TP*T*CP*CP*AP*GP*GP*GP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3', DNA polymerase kappa, ... | 著者 | Lone, S, Townson, S.A, Uljon, S.N, Prakash, S, Prakash, L, Aggarwal, A.K. | 登録日 | 2007-01-09 | 公開日 | 2007-02-27 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Ternary complex of the catalytic core of human DNA polymerase Kappa with DNA and dTT To be Published
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4GAF
| Crystal structure of EBI-005, a chimera of human IL-1beta and IL-1Ra, bound to human Interleukin-1 receptor type 1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, EBI-005, Interleukin-1 receptor type 1, ... | 著者 | Hou, J, Townson, S.A, Kovalchin, J.T, Masci, A, Kiner, O, Shu, Y, King, B, Thomas, C, Garcia, K.C, Furfine, E.S, Barnes, T.M. | 登録日 | 2012-07-25 | 公開日 | 2013-02-20 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Design of a superior cytokine antagonist for topical ophthalmic use. Proc.Natl.Acad.Sci.USA, 110, 2013
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4GAI
| Crystal structure of EBI-005, a chimera of human IL-1beta and IL-1Ra | 分子名称: | EBI-005 | 著者 | Hou, J, Townson, S.A, Kovalchin, J.T, Masci, A, Kiner, O, Shu, Y, King, B, Thomas, C, Garcia, K.C, Furfine, E.S, Barnes, T.M. | 登録日 | 2012-07-25 | 公開日 | 2013-02-20 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | Design of a superior cytokine antagonist for topical ophthalmic use. Proc.Natl.Acad.Sci.USA, 110, 2013
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