5WTZ
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![BU of 5wtz by Molmil](/molmil-images/mine/5wtz) | Crystal structure of C. perfringens iota-like enterotoxin CPILE-a with NAD+ | Descriptor: | Binary enterotoxin of Clostridium perfringens component a, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Toniti, W, Yoshida, T, Tsurumura, T, Irikura, D, Tsuge, H. | Deposit date: | 2016-12-15 | Release date: | 2017-03-01 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.803 Å) | Cite: | Crystal structure and structure-based mutagenesis of actin-specific ADP-ribosylating toxin CPILE-a as novel enterotoxin PLoS ONE, 12, 2017
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5WU0
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![BU of 5wu0 by Molmil](/molmil-images/mine/5wu0) | Crystal structure of C. perfringens iota-like enterotoxin CPILE-a with NADH | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Binary enterotoxin of Clostridium perfringens component a | Authors: | Toniti, W, Yoshida, T, Tsurumura, T, Irikura, D, Tsuge, H. | Deposit date: | 2016-12-15 | Release date: | 2017-03-01 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.251 Å) | Cite: | Crystal structure and structure-based mutagenesis of actin-specific ADP-ribosylating toxin CPILE-a as novel enterotoxin PLoS ONE, 12, 2017
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5GTT
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![BU of 5gtt by Molmil](/molmil-images/mine/5gtt) | Crystal structure of C. perfringens iota-like enterotoxin CPILE-a | Descriptor: | 1,2-ETHANEDIOL, Binary enterotoxin of Clostridium perfringens component a | Authors: | Toniti, W, Yoshida, T, Tsurumura, T, Irikura, D, Tsuge, H. | Deposit date: | 2016-08-23 | Release date: | 2017-03-01 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.011 Å) | Cite: | Crystal structure and structure-based mutagenesis of actin-specific ADP-ribosylating toxin CPILE-a as novel enterotoxin PLoS ONE, 12, 2017
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1GL2
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![BU of 1gl2 by Molmil](/molmil-images/mine/1gl2) | Crystal structure of an endosomal SNARE core complex | Descriptor: | ENDOBREVIN, SYNTAXIN 7, SYNTAXIN 8, ... | Authors: | Antonin, W, Becker, S, Jahn, R, Schneider, T.R. | Deposit date: | 2001-08-22 | Release date: | 2002-01-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structure of the Endosomal Snare Complex Reveals Common Structural Principles of All Snares. Nat.Struct.Biol., 9, 2001
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5A9Q
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![BU of 5a9q by Molmil](/molmil-images/mine/5a9q) | Human nuclear pore complex | Descriptor: | NUCLEAR PORE COMPLEX PROTEIN NUP107, NUCLEAR PORE COMPLEX PROTEIN NUP133, NUCLEAR PORE COMPLEX PROTEIN NUP155, ... | Authors: | von Appen, A, Kosinski, J, Sparks, L, Ori, A, DiGuilio, A, Vollmer, B, Mackmull, M, Banterle, N, Parca, L, Kastritis, P, Buczak, K, Mosalaganti, S, Hagen, W, Andres-Pons, A, Lemke, E.A, Bork, P, Antonin, W, Glavy, J.S, Bui, K.H, Beck, M. | Deposit date: | 2015-07-22 | Release date: | 2015-09-30 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (23 Å) | Cite: | In Situ Structural Analysis of the Human Nuclear Pore Complex Nature, 526, 2015
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5FKI
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![BU of 5fki by Molmil](/molmil-images/mine/5fki) | Pseudorabies virus (PrV) nuclear egress complex proteins fitted as a hexameric lattice into a sub-tomogram average derived from focused- ion beam milled lamellae electron cryo-microscopic data | Descriptor: | CHLORIDE ION, UL31, UL34 protein, ... | Authors: | Hagen, C, Dent, K.C, Zeev Ben Mordehai, T, Vasishtan, D, Antonin, W, Mettenleiter, T.C, Gruenewald, K. | Deposit date: | 2015-10-16 | Release date: | 2016-03-16 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (35 Å) | Cite: | Crystal Structure of the Herpesvirus Nuclear Egress Complex Provides Insights Into Inner Nuclear Membrane Remodelling Cell Rep., 13, 2015
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8FDU
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![BU of 8fdu by Molmil](/molmil-images/mine/8fdu) | Engineered human dynein motor domain in the microtubule-unbound state with LIS1 complex in the buffer containing ATP-Vi (local refined on AAA3-AAA5 and LIS1) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1,Serine--tRNA ligase, Platelet-activating factor acetylhydrolase IB subunit beta,Platelet-activating factor acetylhydrolase IB subunit beta,human LIS1 protein with a SNAP tag | Authors: | Ton, W, Wang, Y, Chai, P. | Deposit date: | 2022-12-04 | Release date: | 2023-06-21 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport. Nat.Struct.Mol.Biol., 30, 2023
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8FCY
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![BU of 8fcy by Molmil](/molmil-images/mine/8fcy) | Engineered human dynein motor domain in microtubule-bound state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1,Serine--tRNA ligase | Authors: | Ton, W, Wang, Y, Chai, P. | Deposit date: | 2022-12-01 | Release date: | 2023-06-21 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport. Nat.Struct.Mol.Biol., 30, 2023
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8FDT
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![BU of 8fdt by Molmil](/molmil-images/mine/8fdt) | Engineered human dynein motor domain in the microtubule-unbound state with LIS1 complex in the buffer containing ATP-Vi | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1,Serine--tRNA ligase, ... | Authors: | Ton, W, Wang, Y, Chai, P. | Deposit date: | 2022-12-04 | Release date: | 2023-06-21 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport. Nat.Struct.Mol.Biol., 30, 2023
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8FD6
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![BU of 8fd6 by Molmil](/molmil-images/mine/8fd6) | Engineered human dynein motor domain in the microtubule-unbound state in the buffer containing ATP-Vi | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1,Serine--tRNA ligase, ... | Authors: | Ton, W, Wang, Y, Chai, P. | Deposit date: | 2022-12-02 | Release date: | 2023-06-21 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport. Nat.Struct.Mol.Biol., 30, 2023
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7RML
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![BU of 7rml by Molmil](/molmil-images/mine/7rml) | Neisseria meningitidis Methylenetetrahydrofolate reductase in complex with FAD | Descriptor: | 5,10-methylenetetrahydrofolate reductase, FLAVIN-ADENINE DINUCLEOTIDE | Authors: | Pederick, J.L, Wegener, K.L, Salaemae, W, Bruning, J.B. | Deposit date: | 2021-07-27 | Release date: | 2022-11-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Biochemical and structural characterization of meningococcal methylenetetrahydrofolate reductase. Protein Sci., 32, 2023
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2AV8
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![BU of 2av8 by Molmil](/molmil-images/mine/2av8) | Y122F MUTANT OF RIBONUCLEOTIDE REDUCTASE FROM ESCHERICHIA COLI | Descriptor: | FE (II) ION, MU-OXO-DIIRON, RIBONUCLEOTIDE REDUCTASE R2 | Authors: | Han, S, Arvai, A, Tainer, J.A. | Deposit date: | 1997-09-30 | Release date: | 1998-10-28 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.46 Å) | Cite: | Characterization of Y122F R2 of Escherichia coli ribonucleotide reductase by time-resolved physical biochemical methods and X-ray crystallography. Biochemistry, 37, 1998
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1AV8
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![BU of 1av8 by Molmil](/molmil-images/mine/1av8) | RIBONUCLEOTIDE REDUCTASE R2 SUBUNIT FROM E. COLI | Descriptor: | MU-OXO-DIIRON, RIBONUCLEOTIDE REDUCTASE R2 | Authors: | Han, S, Arvai, A, Tainer, J.A. | Deposit date: | 1997-09-30 | Release date: | 1998-10-28 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Characterization of Y122F R2 of Escherichia coli ribonucleotide reductase by time-resolved physical biochemical methods and X-ray crystallography. Biochemistry, 37, 1998
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2DHB
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![BU of 2dhb by Molmil](/molmil-images/mine/2dhb) | |
3N4C
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![BU of 3n4c by Molmil](/molmil-images/mine/3n4c) | 6-Phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile as cathepsin S inhibitors | Descriptor: | (E)-1-(1-methyl-6-{4-[3-(4-methylpiperazin-1-yl)propoxy]-3-(trifluoromethyl)phenyl}-1H-imidazo[4,5-c]pyridin-4-yl)methanimine, Cathepsin S, DIMETHYL SULFOXIDE, ... | Authors: | Fradera, X, Uitdehaag, J.C.M, van Zeeland, M. | Deposit date: | 2010-05-21 | Release date: | 2011-04-06 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | 6-Phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile as cathepsin S inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
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8Q2D
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![BU of 8q2d by Molmil](/molmil-images/mine/8q2d) | |
8Q2C
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3OVX
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![BU of 3ovx by Molmil](/molmil-images/mine/3ovx) | |
3OVZ
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![BU of 3ovz by Molmil](/molmil-images/mine/3ovz) | Cathepsin K in complex with a covalent inhibitor with a ketoamide warhead | Descriptor: | Cathepsin K, N-[(1S)-3-amino-1-ethyl-2,3-dioxopropyl]-2-chloro-4-(pyridin-2-ylmethoxy)-3-(trifluoromethyl)benzamide, SULFATE ION | Authors: | Fradera, X, van Zeeland, M, Uitdehaag, J.C.M. | Deposit date: | 2010-09-17 | Release date: | 2010-12-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Trifluoromethylphenyl as P2 for ketoamide-based cathepsin S inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
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2WOM
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![BU of 2wom by Molmil](/molmil-images/mine/2wom) | Crystal Structure of UK-453061 bound to HIV-1 Reverse Transcriptase (K103N). | Descriptor: | 5-{[3,5-diethyl-1-(2-hydroxyethyl)-1H-pyrazol-4-yl]oxy}benzene-1,3-dicarbonitrile, HIV-1 REVERSE TRANSCRIPTASE | Authors: | Phillips, C, Irving, S.L, Knoechel, T, Ringrose, H. | Deposit date: | 2009-07-27 | Release date: | 2010-08-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Lersivirine, a nonnucleoside reverse transcriptase inhibitor with activity against drug-resistant human immunodeficiency virus type 1. Antimicrob. Agents Chemother., 54, 2010
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2WON
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![BU of 2won by Molmil](/molmil-images/mine/2won) | Crystal Structure of UK-453061 bound to HIV-1 Reverse Transcriptase (wild-type). | Descriptor: | 5-{[3,5-diethyl-1-(2-hydroxyethyl)-1H-pyrazol-4-yl]oxy}benzene-1,3-dicarbonitrile, HIV-1 REVERSE TRANSCRIPTASE | Authors: | Phillips, C, Irving, S.L, Knoechel, T, Ringrose, H. | Deposit date: | 2009-07-27 | Release date: | 2010-08-11 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Lersivirine: A Non-Nucleoside Reverse Transcriptase Inhibitor with Activity Against Drug- Resistant Human Immunodeficiency Virus-1. Antimicrob.Agents Chemother., 54, 2010
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5J0N
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![BU of 5j0n by Molmil](/molmil-images/mine/5j0n) | Lambda excision HJ intermediate | Descriptor: | Excisionase, Integrase, Integration host factor subunit alpha, ... | Authors: | Van Duyne, G, Grigorieff, N, Landy, A. | Deposit date: | 2016-03-28 | Release date: | 2017-02-08 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (11 Å) | Cite: | Structure of a Holliday junction complex reveals mechanisms governing a highly regulated DNA transaction. Elife, 5, 2016
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5E8C
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![BU of 5e8c by Molmil](/molmil-images/mine/5e8c) | pseudorabies virus nuclear egress complex, pUL31, pUL34 | Descriptor: | CHLORIDE ION, UL31, UL34 protein, ... | Authors: | Zeev-Ben-Mordehai, T, Cheleski, J, Whittle, C, El Omari, K, Harlos, K, Hagen, C, Klupp, B, Mettenleiter, T.C, Gruenewald, K. | Deposit date: | 2015-10-14 | Release date: | 2015-12-23 | Last modified: | 2016-01-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal Structure of the Herpesvirus Nuclear Egress Complex Provides Insights into Inner Nuclear Membrane Remodeling. Cell Rep, 13, 2015
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3KW9
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3KWZ
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![BU of 3kwz by Molmil](/molmil-images/mine/3kwz) | |