6VVC
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6VVE
| Legionella pneumophila Lpg2603 kinase bound to IP6, Mn2+, and ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Dot/Icm T4SS effector, INOSITOL HEXAKISPHOSPHATE, ... | Authors: | Tomchick, D.R, Tagliabracci, V.S, Park, B.C. | Deposit date: | 2020-02-17 | Release date: | 2020-04-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | ALegionellaeffector kinase is activated by host inositol hexakisphosphate. J.Biol.Chem., 295, 2020
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6VVD
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6MYI
| Pleurotus ostreatus OstreolysinA | Descriptor: | 1,2-ETHANEDIOL, Ostreolysin A6, SODIUM ION | Authors: | Tomchick, D.R, Radhakrishnan, A, Endapally, S. | Deposit date: | 2018-11-01 | Release date: | 2019-02-13 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Molecular Discrimination between Two Conformations of Sphingomyelin in Plasma Membranes. Cell, 176, 2019
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6N1Z
| Importin-9 bound to H2A-H2B | Descriptor: | Histone H2A, Histone H2B 1.1, Importin-9 | Authors: | Tomchick, D.R, Chook, Y.M, Padavannil, A. | Deposit date: | 2018-11-12 | Release date: | 2019-03-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Importin-9 wraps around the H2A-H2B core to act as nuclear importer and histone chaperone. Elife, 8, 2019
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6NYT
| Munc13-1 C2B-domain, calcium bound | Descriptor: | CALCIUM ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Tomchick, D.R, Rizo, J, Machius, M, Lu, J. | Deposit date: | 2019-02-12 | Release date: | 2019-02-20 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.369 Å) | Cite: | Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis. Nat. Struct. Mol. Biol., 17, 2010
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6NYC
| Munc13-1 C2B-domain, calcium free | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Munc13-1 | Authors: | Tomchick, D.R, Rizo, J, Machius, M, Lu, J. | Deposit date: | 2019-02-11 | Release date: | 2019-02-20 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.893 Å) | Cite: | Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis. Nat. Struct. Mol. Biol., 17, 2010
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6OQQ
| Legionella pneumophila SidJ/Saccharomyces cerevisiae calmodulin complex | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, CALCIUM ION, ... | Authors: | Tomchick, D.R, Tagliabracci, V.S, Black, M, Osinski, A. | Deposit date: | 2019-04-28 | Release date: | 2019-05-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.102 Å) | Cite: | Bacterial pseudokinase catalyzes protein polyglutamylation to inhibit the SidE-family ubiquitin ligases. Science, 364, 2019
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6PWD
| Ewingella americana HopBF1 kinase | Descriptor: | 1,2-ETHANEDIOL, SULFATE ION, Type III effector HopBF1 | Authors: | Tomchick, D.R, Tagliabracci, V.S, Park, B.C. | Deposit date: | 2019-07-22 | Release date: | 2019-09-11 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | A Bacterial Effector Mimics a Host HSP90 Client to Undermine Immunity. Cell, 179, 2019
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6PWG
| Ewingella americana HopBF1 kinase bound to AMP-PNP | Descriptor: | 1,2-ETHANEDIOL, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Type III effector HopBF1 | Authors: | Tomchick, D.R, Tagliabracci, V.S, Park, B.C. | Deposit date: | 2019-07-23 | Release date: | 2019-09-11 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | A Bacterial Effector Mimics a Host HSP90 Client to Undermine Immunity. Cell, 179, 2019
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4IG1
| Crystal structure of Treponema pallidum TP0796 Flavin trafficking protein, Mg(II)-AMP product bound form | Descriptor: | ACETATE ION, ADENOSINE MONOPHOSPHATE, FAD:protein FMN transferase, ... | Authors: | Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V. | Deposit date: | 2012-12-15 | Release date: | 2013-02-27 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.4318 Å) | Cite: | The TP0796 Lipoprotein of Treponema pallidum Is a Bimetal-dependent FAD Pyrophosphatase with a Potential Role in Flavin Homeostasis. J.Biol.Chem., 288, 2013
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4IFW
| Crystal structure of Treponema pallidum TP0796 Flavin trafficking protein, ADP inhibited form | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Thiamine biosynthesis lipoprotein ApbE | Authors: | Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V. | Deposit date: | 2012-12-15 | Release date: | 2013-02-27 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.3001 Å) | Cite: | The TP0796 Lipoprotein of Treponema pallidum Is a Bimetal-dependent FAD Pyrophosphatase with a Potential Role in Flavin Homeostasis. J.Biol.Chem., 288, 2013
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4IFX
| Crystal structure of Treponema pallidum TP0796 Flavin trafficking protein, FAD substrate bound form | Descriptor: | ACETATE ION, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, ... | Authors: | Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V. | Deposit date: | 2012-12-15 | Release date: | 2013-02-27 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.452 Å) | Cite: | The TP0796 Lipoprotein of Treponema pallidum Is a Bimetal-dependent FAD Pyrophosphatase with a Potential Role in Flavin Homeostasis. J.Biol.Chem., 288, 2013
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4IFZ
| Crystal structure of Treponema pallidum TP0796 Flavin trafficking protein, Mn(II)-AMP product bound form | Descriptor: | ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, MANGANESE (II) ION, ... | Authors: | Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V. | Deposit date: | 2012-12-15 | Release date: | 2013-02-27 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.9012 Å) | Cite: | The TP0796 Lipoprotein of Treponema pallidum Is a Bimetal-dependent FAD Pyrophosphatase with a Potential Role in Flavin Homeostasis. J.Biol.Chem., 288, 2013
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4IFU
| Crystal structure of Treponema pallidum TP0796 Flavin trafficking protein, apo form | Descriptor: | FAD:protein FMN transferase, MAGNESIUM ION | Authors: | Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V. | Deposit date: | 2012-12-15 | Release date: | 2013-02-27 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.8334 Å) | Cite: | The TP0796 Lipoprotein of Treponema pallidum Is a Bimetal-dependent FAD Pyrophosphatase with a Potential Role in Flavin Homeostasis. J.Biol.Chem., 288, 2013
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3N5A
| Synaptotagmin-7, C2B-domain, calcium bound | Descriptor: | CALCIUM ION, Synaptotagmin-7 | Authors: | Tomchick, D.R, Rizo, J, Craig, T.K. | Deposit date: | 2010-05-24 | Release date: | 2010-09-29 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.441 Å) | Cite: | Structural and mutational analysis of functional differentiation between synaptotagmins-1 and -7. Plos One, 5, 2010
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3OBV
| Autoinhibited Formin mDia1 Structure | Descriptor: | Protein diaphanous homolog 1, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose | Authors: | Tomchick, D.R, Rosen, M.K, Otomo, T. | Deposit date: | 2010-08-09 | Release date: | 2010-11-24 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Crystal structure of the Formin mDia1 in autoinhibited conformation. Plos One, 5, 2010
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3PCR
| Structure of EspG-Arf6 complex | Descriptor: | ADP-ribosylation factor 6, EspG, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Tomchick, D.R, Alto, N.M, Selyunin, A.S. | Deposit date: | 2010-10-21 | Release date: | 2011-01-05 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The assembly of a GTPase-kinase signalling complex by a bacterial catalytic scaffold. Nature, 469, 2011
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3PCS
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2QYF
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5T8V
| Chaetomium thermophilum cohesin loader SCC2, C-terminal fragment | Descriptor: | CITRIC ACID, Putative uncharacterized protein | Authors: | Tomchick, D.R, Yu, H, Kikuchi, S, Ouyang, Z, Borek, D, Otwinowski, Z. | Deposit date: | 2016-09-08 | Release date: | 2016-10-19 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.798 Å) | Cite: | Crystal structure of the cohesin loader Scc2 and insight into cohesinopathy. Proc.Natl.Acad.Sci.USA, 113, 2016
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4K6J
| Human cohesin inhibitor WapL | Descriptor: | ACETATE ION, SULFATE ION, Wings apart-like protein homolog | Authors: | Tomchick, D.R, Yu, H, Ouyang, Z. | Deposit date: | 2013-04-16 | Release date: | 2013-06-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.6205 Å) | Cite: | Structure of the human cohesin inhibitor Wapl. Proc.Natl.Acad.Sci.USA, 110, 2013
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3BND
| Lipoxygenase-1 (Soybean), I553V Mutant | Descriptor: | FE (III) ION, Seed lipoxygenase-1 | Authors: | Tomchick, D.R. | Deposit date: | 2007-12-14 | Release date: | 2008-04-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Enzyme structure and dynamics affect hydrogen tunneling: the impact of a remote side chain (I553) in soybean lipoxygenase-1. Proc.Natl.Acad.Sci.Usa, 105, 2008
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3BNE
| Lipoxygenase-1 (Soybean) I553A Mutant | Descriptor: | FE (III) ION, Seed lipoxygenase-1 | Authors: | Tomchick, D.R. | Deposit date: | 2007-12-14 | Release date: | 2008-04-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Enzyme structure and dynamics affect hydrogen tunneling: the impact of a remote side chain (I553) in soybean lipoxygenase-1. Proc.Natl.Acad.Sci.Usa, 105, 2008
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3BNB
| Lipoxygenase-1 (Soybean) I553L Mutant | Descriptor: | FE (III) ION, Seed lipoxygenase-1 | Authors: | Tomchick, D.R. | Deposit date: | 2007-12-14 | Release date: | 2008-04-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Enzyme structure and dynamics affect hydrogen tunneling: the impact of a remote side chain (I553) in soybean lipoxygenase-1. Proc.Natl.Acad.Sci.Usa, 105, 2008
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