3IA7
 
 | | Crystal Structure of CalG4, the Calicheamicin Glycosyltransferase | | 分子名称: | CALCIUM ION, CHLORIDE ION, CalG4 | | 著者 | Chang, A, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N. | | 登録日 | 2009-07-13 | | 公開日 | 2010-06-02 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity.
Proc.Natl.Acad.Sci.USA, 108, 2011
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4K0B
 | | Crystal structure of S-Adenosylmethionine synthetase from Sulfolobus solfataricus complexed with SAM and PPi | | 分子名称: | DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | Wang, F, Hurley, K.A, Helmich, K.E, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2013-04-03 | | 公開日 | 2013-05-01 | | 最終更新日 | 2014-10-08 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Understanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT from Sulfolobus solfataricus.
Febs J., 281, 2014
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4L7I
 | | Crystal structure of S-Adenosylmethionine synthase from Sulfolobus solfataricus complexed with SAM and PPi | | 分子名称: | DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | Wang, F, Hurley, K.A, Helmich, K.E, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2013-06-13 | | 公開日 | 2013-07-03 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.189 Å) | | 主引用文献 | Understanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT from Sulfolobus solfataricus.
Febs J., 281, 2014
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4L2Z
 | | Crystal structure of S-Adenosylmethionine synthetase from Sulfolobus solfataricus complexed with SAE and PPi | | 分子名称: | DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | Wang, F, Hurley, K.A, Helmich, K.E, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2013-06-05 | | 公開日 | 2013-06-19 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.494 Å) | | 主引用文献 | Understanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT from Sulfolobus solfataricus.
Febs J., 281, 2014
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4M83
 | | Ensemble refinement of protein crystal structure (2IYF) of macrolide glycosyltransferases OleD complexed with UDP and Erythromycin A | | 分子名称: | ERYTHROMYCIN A, MAGNESIUM ION, Oleandomycin glycosyltransferase, ... | | 著者 | Wang, F, Helmich, K.E, Xu, W, Singh, S, Olmos Jr, J.L, Martinez iii, E, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2013-08-12 | | 公開日 | 2013-09-11 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.698 Å) | | 主引用文献 | Crystal structure of macrolide glycosyltransferases OleD
To be Published
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4M60
 | | Crystal structure of macrolide glycosyltransferases OleD | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Oleandomycin glycosyltransferase, SODIUM ION | | 著者 | Olmos Jr, J.L, Martinez III, E, Wang, F, Helmich, K.E, Singh, S, Xu, W, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2013-08-08 | | 公開日 | 2013-09-04 | | 最終更新日 | 2019-07-17 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Crystal structure of macrolide glycosyltransferases OleD
To be Published
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4M7P
 | | Ensemble refinement of protein crystal structure of macrolide glycosyltransferases OleD | | 分子名称: | Oleandomycin glycosyltransferase, SODIUM ION | | 著者 | Wang, F, Helmich, K.E, Xu, W, Singh, S, Olmos Jr, J.L, Martinez iii, E, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2013-08-12 | | 公開日 | 2013-09-11 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Crystal structure of macrolide glycosyltransferases OleD
To be Published
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4PIW
 | | Crystal structure of sugar aminotransferase WecE from Escherichia coli K-12 | | 分子名称: | TDP-4-keto-6-deoxy-D-glucose transaminase family protein | | 著者 | Wang, F, Xu, W, Helmich, K.E, Singh, S, Yennamalli, R.M, Miller, M.D, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2014-05-09 | | 公開日 | 2014-07-16 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of sugar aminotransferase WecE from Escherichia coli K-12
To Be Published
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4Q31
 | | The crystal structure of cystathione gamma lyase (CalE6) from Micromonospora echinospora | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, FORMIC ACID, ... | | 著者 | Tan, K, Bigelow, L, Jedrzejczak, R, Babnigg, G, Bingman, C.A, Yennamalli, R.M, Singh, S, Kharel, M.K, Thorson, J.S, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2014-04-10 | | 公開日 | 2014-05-07 | | 最終更新日 | 2017-03-08 | | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | | 主引用文献 | Structural dynamics of a methionine gamma-lyase for calicheamicin biosynthesis: Rotation of the conserved tyrosine stacking with pyridoxal phosphate.
Struct Dyn, 3, 2016
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3PKP
 | | Q83S Variant of S. Enterica RmlA with dATP | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Glucose-1-phosphate thymidylyltransferase, MAGNESIUM ION | | 著者 | Chang, A, Moretti, R, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | | 登録日 | 2010-11-11 | | 公開日 | 2011-01-12 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Expanding the Nucleotide and Sugar 1-Phosphate Promiscuity of Nucleotidyltransferase RmlA via Directed Evolution.
J.Biol.Chem., 286, 2011
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3PKQ
 | | Q83D Variant of S. Enterica RmlA with dGTP | | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, Glucose-1-phosphate thymidylyltransferase, ... | | 著者 | Chang, A, Moretti, R, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | | 登録日 | 2010-11-11 | | 公開日 | 2011-01-12 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Expanding the Nucleotide and Sugar 1-Phosphate Promiscuity of Nucleotidyltransferase RmlA via Directed Evolution.
J.Biol.Chem., 286, 2011
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3RSC
 | | Crystal Structure of CalG2, Calicheamicin Glycosyltransferase, TDP and calicheamicin T0 bound form | | 分子名称: | CalG2, Calicheamicin T0, PHOSPHATE ION, ... | | 著者 | Chang, A, Helmich, K.E, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2011-05-02 | | 公開日 | 2011-08-10 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3TOS
 | | Crystal Structure of CalS11, Calicheamicin Methyltransferase | | 分子名称: | 1,2-ETHANEDIOL, CalS11, GLUTAMIC ACID, ... | | 著者 | Chang, A, Aceti, D.J, Beebe, E.T, Makino, S.-I, Wrobel, R.L, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2011-09-06 | | 公開日 | 2011-10-05 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Crystal Structure of CalS11, Calicheamicin methyltransferase
To be Published
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3D0R
 | | Crystal structure of calG3 from Micromonospora echinospora determined in space group P2(1) | | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Protein CalG3 | | 著者 | Bitto, E, Bingman, C.A, Wesenberg, G.E, Phillips Jr, G.N. | | 登録日 | 2008-05-02 | | 公開日 | 2008-06-24 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Biochemical and structural insights of the early glycosylation steps in calicheamicin biosynthesis.
Chem.Biol., 15, 2008
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3D0Q
 | | Crystal structure of calG3 from Micromonospora echinospora determined in space group I222 | | 分子名称: | 3[N-MORPHOLINO]PROPANE SULFONIC ACID, Protein CalG3 | | 著者 | Bitto, E, Singh, S, Bingman, C.A, Wesenberg, G.E, Phillips Jr, G.N. | | 登録日 | 2008-05-02 | | 公開日 | 2008-06-24 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | Biochemical and structural insights of the early glycosylation steps in calicheamicin biosynthesis.
Chem.Biol., 15, 2008
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4ZWV
 | | Crystal Structure of Aminotransferase AtmS13 from Actinomadura melliaura | | 分子名称: | GLYCEROL, Putative aminotransferase | | 著者 | Kim, Y, Bigelow, L, Endres, M, Wang, F, Phillips Jr, G.N, Joachimiak, A, Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2015-05-19 | | 公開日 | 2015-06-03 | | 最終更新日 | 2019-12-04 | | 実験手法 | X-RAY DIFFRACTION (1.503 Å) | | 主引用文献 | Structural characterization of AtmS13, a putative sugar aminotransferase involved in indolocarbazole AT2433 aminopentose biosynthesis.
Proteins, 83, 2015
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2OA1
 | | Crystal Structure of RebH, a FAD-dependent halogenase from Lechevalieria aerocolonigenes, the L-Tryptophan with FAD complex | | 分子名称: | ADENOSINE, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Bitto, E, Bingman, C.A, Singh, S, Phillips Jr, G.N. | | 登録日 | 2006-12-14 | | 公開日 | 2007-04-10 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | The structure of flavin-dependent tryptophan 7-halogenase RebH.
Proteins, 70, 2008
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2O9Z
 | | Crystal Structure of RebH, a FAD-dependent halogenase from Lechevalieria aerocolonigenes, the Apo form | | 分子名称: | PHOSPHATE ION, Tryptophan halogenase | | 著者 | Bitto, E, Bingman, C.A, Phillips Jr, G.N. | | 登録日 | 2006-12-14 | | 公開日 | 2007-04-10 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.494 Å) | | 主引用文献 | The structure of flavin-dependent tryptophan 7-halogenase RebH.
Proteins, 70, 2008
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4FPW
 | | Crystal Structure of CalU16 from Micromonospora echinospora. Northeast Structural Genomics Consortium Target MiR12. | | 分子名称: | CalU16 | | 著者 | Seetharaman, J, Lew, S, Janjua, H, Xiao, R, Acton, T.B, Everett, J.K, Phillips Jr, G.N, Kennedy, M.A, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2012-06-22 | | 公開日 | 2012-12-12 | | 最終更新日 | 2014-11-12 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure-Guided Functional Characterization of Enediyne Self-Sacrifice Resistance Proteins, CalU16 and CalU19.
Acs Chem.Biol., 9, 2014
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4RIE
 | | Landomycin Glycosyltransferase LanGT2 | | 分子名称: | Glycosyl transferase homolog | | 著者 | Tam, H.K, Gerhardt, S, Breit, B, Bechthold, A, Einsle, O. | | 登録日 | 2014-10-06 | | 公開日 | 2015-01-28 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.162 Å) | | 主引用文献 | Structural Characterization of O- and C-Glycosylating Variants of the Landomycin Glycosyltransferase LanGT2.
Angew.Chem.Int.Ed.Engl., 54, 2015
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4RIF
 | | Landomycin Glycosyltransferase LanGT2, carbasugar substrate complex | | 分子名称: | 2'-deoxy-5'-O-[(R)-{[(R)-{[(1S,3R,4R,5S)-3,4-dihydroxy-5-methylcyclohexyl]oxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]-3,4-dihydrothymidine, Glycosyl transferase homolog | | 著者 | Tam, H.K, Gerhardt, S, Breit, B, Bechthold, A, Einsle, O. | | 登録日 | 2014-10-06 | | 公開日 | 2015-01-28 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural Characterization of O- and C-Glycosylating Variants of the Landomycin Glycosyltransferase LanGT2.
Angew.Chem.Int.Ed.Engl., 54, 2015
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4RIG
 | | Chimeric Glycosyltransferase LanGT2S8Ac | | 分子名称: | Glycosyl transferase, MAGNESIUM ION | | 著者 | Tam, H.K, Gerhardt, S, Breit, B, Bechthold, A, Einsle, O. | | 登録日 | 2014-10-06 | | 公開日 | 2015-01-28 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural Characterization of O- and C-Glycosylating Variants of the Landomycin Glycosyltransferase LanGT2.
Angew.Chem.Int.Ed.Engl., 54, 2015
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4RIH
 | | Chimeric Glycosyltransferase LanGT2S8Ac, carbasugar substrate complex | | 分子名称: | 2'-deoxy-5'-O-[(R)-{[(R)-{[(1S,3R,4R,5S)-3,4-dihydroxy-5-methylcyclohexyl]oxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]-3,4-dihydrothymidine, Glycosyl transferase homolog,Glycosyl transferase, MAGNESIUM ION | | 著者 | Tam, H.K, Gerhardt, S, Breit, B, Bechthold, A, Einsle, O. | | 登録日 | 2014-10-06 | | 公開日 | 2015-01-28 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | | 主引用文献 | Structural Characterization of O- and C-Glycosylating Variants of the Landomycin Glycosyltransferase LanGT2.
Angew.Chem.Int.Ed.Engl., 54, 2015
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4RII
 | | Chimeric Glycosyltransferase LanGT2S8Ac, TDP complex | | 分子名称: | Glycosyl transferase homolog,Glycosyl transferase, MAGNESIUM ION, THYMIDINE-5'-DIPHOSPHATE | | 著者 | Tam, H.K, Gerhardt, S, Breit, B, Bechthold, A, Einsle, O. | | 登録日 | 2014-10-06 | | 公開日 | 2015-01-28 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural Characterization of O- and C-Glycosylating Variants of the Landomycin Glycosyltransferase LanGT2.
Angew.Chem.Int.Ed.Engl., 54, 2015
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4GF5
 | | Crystal Structure of Calicheamicin Methyltransferase, CalS11 | | 分子名称: | CalS11, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION | | 著者 | Helmich, K.E, Singh, S, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro), Center for Eukaryotic Structural Genomics (CESG) | | 登録日 | 2012-08-02 | | 公開日 | 2012-08-22 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 |
to be published
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