5TRE
| Zinc and the Iron Donor Frataxin Regulate Oligomerization of the Scaffold Protein to Form New Fe-S Cluster Assembly Centers | 分子名称: | Frataxin homolog, mitochondrial, Iron sulfur cluster assembly protein 1 | 著者 | Ranatunga, W, Gakh, O, Galeano, B.K, Smith IV, D.Y, Thompson, J.R, Isaya, G. | 登録日 | 2016-10-26 | 公開日 | 2017-06-07 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (15.6 Å) | 主引用文献 | Zinc and the iron donor frataxin regulate oligomerization of the scaffold protein to form new Fe-S cluster assembly centers. Metallomics, 9, 2017
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5UMS
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5UMV
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5UMU
| Crystal structure of the middle double PH domain of human FACT complex subunit SPT16 | 分子名称: | ACETATE ION, FACT complex subunit SPT16, FORMIC ACID | 著者 | Hu, Q, Thompson, J.R, Heroux, A, Su, D, Botuyan, M.V, Mer, G. | 登録日 | 2017-01-29 | 公開日 | 2018-01-31 | 最終更新日 | 2019-12-04 | 実験手法 | X-RAY DIFFRACTION (1.903 Å) | 主引用文献 | Crystal structure of the middle double PH domain of human FACT complex subunit SPT16 To Be Published
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5UMR
| Crystal structure of N-terminal domain of human FACT complex subunit SSRP1 | 分子名称: | FACT complex subunit SSRP1 | 著者 | Su, D, Hu, Q, Thompson, J.R, Heroux, A, Botuyan, M.V, Mer, G. | 登録日 | 2017-01-29 | 公開日 | 2018-01-31 | 最終更新日 | 2019-12-04 | 実験手法 | X-RAY DIFFRACTION (1.501 Å) | 主引用文献 | Crystal structure of N-terminal domain of human FACT complex subunit SSRP1 To Be Published
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5UMT
| Crystal structure of N-terminal domain of human FACT complex subunit SPT16 | 分子名称: | 1,2-ETHANEDIOL, FACT complex subunit SPT16, GLYCEROL | 著者 | Su, D, Hu, Q, Thompson, J.R, Botuyan, M.V, Mer, G. | 登録日 | 2017-01-29 | 公開日 | 2018-01-31 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.092 Å) | 主引用文献 | Crystal structure of N-terminal domain of human FACT complex subunit SPT16 To Be Published
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6CO1
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6D0L
| Structure of human TIRR | 分子名称: | Tudor-interacting repair regulator protein | 著者 | Cui, G, Botuyan, M.V, Mer, G. | 登録日 | 2018-04-10 | 公開日 | 2018-06-06 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein. Nat. Struct. Mol. Biol., 25, 2018
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2QQR
| JMJD2A hybrid tudor domains | 分子名称: | JmjC domain-containing histone demethylation protein 3A, SULFATE ION | 著者 | Lee, J, Botuyan, M.V, Mer, G. | 登録日 | 2007-07-26 | 公開日 | 2007-12-11 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor. Nat.Struct.Mol.Biol., 15, 2008
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2QQS
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4W8Q
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2IG0
| Structure of 53BP1/methylated histone peptide complex | 分子名称: | Dimethylated Histone H4-K20 peptide, SULFATE ION, Tumor suppressor p53-binding protein 1 | 著者 | Mer, G. | 登録日 | 2006-09-22 | 公開日 | 2007-01-02 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural Basis for the Methylation State-Specific Recognition of Histone H4-K20 by 53BP1 and Crb2 in DNA Repair. Cell(Cambridge,Mass.), 127, 2006
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2KRE
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2LDM
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2LH0
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6MXY
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6MXZ
| Structure of 53BP1 Tudor domains in complex with small molecule UNC3474 | 分子名称: | FORMIC ACID, N-[3-(tert-butylamino)propyl]-3-(propan-2-yl)benzamide, TP53-binding protein 1 | 著者 | Cui, G, Botuyan, M.V, Schuller, D.J, Mer, G. | 登録日 | 2018-10-31 | 公開日 | 2019-11-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering. Nat Commun, 14, 2023
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6MY0
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6MXX
| Structure of 53BP1 tandem Tudor domains in complex with small molecule UNC2991 | 分子名称: | FORMIC ACID, N-[3-(tert-butylamino)propyl]-3-iodobenzamide, PHOSPHATE ION, ... | 著者 | Cui, G, Botuyan, M.V, Mer, G. | 登録日 | 2018-10-31 | 公開日 | 2019-11-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.298 Å) | 主引用文献 | An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering. Nat Commun, 14, 2023
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8SMY
| Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A. No density for Ub.) (class 3) | 分子名称: | DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | 著者 | Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. | 登録日 | 2023-04-26 | 公開日 | 2024-01-17 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
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8SN4
| Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A) (class 2) | 分子名称: | DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | 著者 | Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. | 登録日 | 2023-04-26 | 公開日 | 2024-01-17 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
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8SN5
| Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A) (class 3) | 分子名称: | DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | 著者 | Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. | 登録日 | 2023-04-26 | 公開日 | 2024-01-17 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
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8SNA
| Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c with backside ubiquitin (UbcH5c chemically conjugated to histone H2A) (class 2) | 分子名称: | DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | 著者 | Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. | 登録日 | 2023-04-26 | 公開日 | 2024-01-17 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
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8SMX
| Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A. No density for Ub.) (class 2) | 分子名称: | DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | 著者 | Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. | 登録日 | 2023-04-26 | 公開日 | 2024-01-17 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
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8SN2
| Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c (UbcH5c chemically conjugated to histone H2A) | 分子名称: | DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | 著者 | Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. | 登録日 | 2023-04-26 | 公開日 | 2024-01-17 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
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