1MB1
 
 | | MBP1 FROM SACCHAROMYCES CEREVISIAE | | 分子名称: | MLU1-BOX BINDING PROTEIN | | 著者 | Taylor, I.A, Smerdon, S.J. | | 登録日 | 1997-07-23 | | 公開日 | 1998-07-29 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The X-ray structure of the DNA-binding domain from the Saccharomyces cerevisiae cell-cycle transcription factor Mbp1 at 2.1 A resolution.
J.Mol.Biol., 272, 1997
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5M1H
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2XFV
 | | Structure of the amino-terminal domain from the cell-cycle regulator Swi6 | | 分子名称: | ACETATE ION, CACODYLATE ION, CALCIUM ION, ... | | 著者 | Smerdon, S.J, Goldstone, D.C, Taylor, I.A. | | 登録日 | 2010-05-27 | | 公開日 | 2010-06-23 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of the Amino-Terminal Domain from the Cell-Cycle Regulator Swi6S
Proteins, 78, 2010
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4JMR
 | | A unique spumavirus gag N-terminal domain with functional properties of orthoretroviral Matrix and Capsid | | 分子名称: | Env protein, Gag protein | | 著者 | Taylor, I.A, Goldstone, D.C, Flower, T.G, Ball, N.J. | | 登録日 | 2013-03-14 | | 公開日 | 2013-05-29 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | A Unique Spumavirus Gag N-terminal Domain with Functional Properties of Orthoretroviral Matrix and Capsid.
Plos Pathog., 9, 2013
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4JNH
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7ZUD
 | | Crystal structure of HIV-1 capsid IP6-CPSF6 complex | | 分子名称: | Capsid protein p24, Cleavage and polyadenylation specificity factor subunit 6, INOSITOL HEXAKISPHOSPHATE | | 著者 | Nicastro, G, Taylor, I.A. | | 登録日 | 2022-05-12 | | 公開日 | 2022-07-27 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.93 Å) | | 主引用文献 | CP-MAS and Solution NMR Studies of Allosteric Communication in CA-assemblies of HIV-1.
J.Mol.Biol., 434, 2022
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4UX5
 | | Structure of DNA complex of PCG2 | | 分子名称: | 5'-D(*CP*AP*AP*TP*GP*AP*CP*GP*CP*GP*TP*AP*AP*GP)-3', 5'-D(*CP*TP*TP*AP*CP*GP*CP*GP*TP*CP*AP*TP*TP*GP)-3', TRANSCRIPTION FACTOR MBP1 | | 著者 | Liu, J, Huang, J, Zhao, Y, Liu, H, Wang, D, Yang, J, Zhao, W, Taylor, I.A, Peng, Y. | | 登録日 | 2014-08-19 | | 公開日 | 2015-01-14 | | 最終更新日 | 2015-02-04 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural Basis of DNA Recognition by Pcg2 Reveals a Novel DNA Binding Mode for Winged Helix-Turn-Helix Domains.
Nucleic Acids Res., 43, 2015
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5M1G
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6XU1
 | | Crystal structure of tetrameric human H215A-SAMHD1 (residues 109-626) with GTP, dAMPNPP and Mg | | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, FE (III) ION, ... | | 著者 | Morris, E.R, Kunzelmann, S, Caswell, S.J, Arnold, L.H, Purkiss, A.G, Kelly, G, Taylor, I.A. | | 登録日 | 2020-01-17 | | 公開日 | 2020-06-24 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structures of SAMHD1 inhibitor complexes reveal the mechanism of water-mediated dNTP hydrolysis.
Nat Commun, 11, 2020
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6YOM
 | | Crystal structure of tetrameric human D137N-SAMHD1 (residues 109-626) with XTP, dATP, dCMPNPP, Mn and Mg | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ... | | 著者 | Morris, E.R, Kunzelmann, S, Caswell, S.J, Arnold, L.H, Purkiss, A.G, Kelly, G, Taylor, I.A. | | 登録日 | 2020-04-14 | | 公開日 | 2020-06-24 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Crystal structures of SAMHD1 inhibitor complexes reveal the mechanism of water-mediated dNTP hydrolysis.
Nat Commun, 11, 2020
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7A5Y
 | | Crystal structure of tetrameric human H215A-SAMHD1 (residues 109-626) with Rp-dGTP-alphaS (T8T) and Mg | | 分子名称: | 2'-deoxyguanosine-5'-O-(1-thiotriphosphate), Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, FE (III) ION, ... | | 著者 | Morris, E.R, Kunzelmann, S, Caswell, S.J, Purkiss, A, Taylor, I.A. | | 登録日 | 2020-08-24 | | 公開日 | 2021-05-26 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Probing the Catalytic Mechanism and Inhibition of SAMHD1 Using the Differential Properties of R p - and S p -dNTP alpha S Diastereomers.
Biochemistry, 60, 2021
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6ZUE
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4TN3
 | | Structure of the BBox-Coiled-coil region of Rhesus Trim5alpha | | 分子名称: | TRIM5/cyclophilin A fusion protein/T4 Lysozyme chimera, ZINC ION | | 著者 | Kirkpatrick, J.J, Stoye, J.P, Taylor, I.A, Goldstone, D.C. | | 登録日 | 2014-06-03 | | 公開日 | 2014-07-16 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.1989 Å) | | 主引用文献 | Structural studies of postentry restriction factors reveal antiparallel dimers that enable avid binding to the HIV-1 capsid lattice.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4CC9
 | | Crystal structure of human SAMHD1 (amino acid residues 582-626) bound to Vpx isolated from sooty mangabey and human DCAF1 (amino acid residues 1058-1396) | | 分子名称: | DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1, PROTEIN VPRBP, PROTEIN VPX, ... | | 著者 | Schwefel, D, Groom, H.C.T, Boucherit, V.C, Christodoulou, E, Walker, P.A, Stoye, J.P, Bishop, K.N, Taylor, I.A. | | 登録日 | 2013-10-19 | | 公開日 | 2013-12-11 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.473 Å) | | 主引用文献 | Structural Basis of Lentiviral Subversion of a Cellular Protein Degradation Pathway.
Nature, 505, 2014
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6ES4
 | | A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets | | 分子名称: | 1,2-ETHANEDIOL, SULFATE ION, Syncrip, ... | | 著者 | Hobor, F, Dallmann, A, Ball, N.J, Cicchini, C, Battistelli, C, Ogrodowicz, R.W, Christodoulou, E, Martin, S.R, Castello, A, Tripodi, M, Taylor, I.A, Ramos, A. | | 登録日 | 2017-10-19 | | 公開日 | 2018-03-07 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets.
Nat Commun, 9, 2018
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7NLI
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7NLH
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7NLG
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8COO
 | | Solution structure of Zipcode binding protein 1 (ZBP1) KH3(DD)KH4 domains in complex with N6-Methyladenosine containing RNA | | 分子名称: | Insulin-like growth factor 2 mRNA-binding protein 1, RNA_(5'-R(*(UP*CP*GP*GP*(6MZ)P*CP*U)-3') | | 著者 | Nicastro, G, Abis, G, Taylor, I.A, Ramos, A. | | 登録日 | 2023-02-28 | | 公開日 | 2024-02-07 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Direct m6A recognition by IMP1 underlays an alternative model of target selection for non-canonical methyl-readers.
Nucleic Acids Res., 51, 2023
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2V4X
 | | Crystal Structure of Jaagsiekte Sheep Retrovirus Capsid N-terminal domain | | 分子名称: | CAPSID PROTEIN P27 | | 著者 | Mortuza, G.B, Goldstone, D.C, Pashley, C, Haire, L.F, Palmarini, M, Taylor, W.R, Stoye, J.P, Taylor, I.A. | | 登録日 | 2008-09-30 | | 公開日 | 2008-11-25 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure of the Capsid Amino-Terminal Domain from the Betaretrovirus, Jaagsiekte Sheep Retrovirus.
J.Mol.Biol., 386, 2009
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5Z1V
 | | Crystal structure of AvrPib | | 分子名称: | AvrPib protein | | 著者 | Zhang, X, He, D, Zhao, Y.X, Taylor, I.A, Peng, Y.L, Yang, J, Liu, J.F. | | 登録日 | 2017-12-28 | | 公開日 | 2018-09-05 | | 最終更新日 | 2018-10-03 | | 実験手法 | X-RAY DIFFRACTION (1.661 Å) | | 主引用文献 | A positive-charged patch and stabilized hydrophobic core are essential for avirulence function of AvrPib in the rice blast fungus.
Plant J., 96, 2018
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3BP9
 | | Structure of B-tropic MLV capsid N-terminal domain | | 分子名称: | GLYCEROL, Gag protein, ISOPROPYL ALCOHOL | | 著者 | Gulnahar, M.B, Dodding, M.P, Goldstone, D.C, Haire, L.F, Stoye, J.P, Taylor, I.A. | | 登録日 | 2007-12-18 | | 公開日 | 2008-02-12 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of B-MLV capsid amino-terminal domain reveals key features of viral tropism, gag assembly and core formation
J.Mol.Biol., 376, 2008
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6QEY
 | | IMP1 KH1 and KH2 domains create a structural platform with unique RNA recognition and re-modelling properties | | 分子名称: | ACETONITRILE, Insulin-like growth factor 2 mRNA-binding protein 1, PHOSPHATE ION | | 著者 | Dagil, R, Ball, N.J, Ogrodowicz, R.W, Purkiss, A.G, Taylor, I.A, Ramos, A. | | 登録日 | 2019-01-09 | | 公開日 | 2019-03-27 | | 最終更新日 | 2019-09-18 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | IMP1 KH1 and KH2 domains create a structural platform with unique RNA recognition and re-modelling properties.
Nucleic Acids Res., 47, 2019
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5AO2
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5AO0
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