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4Q71
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BU of 4q71 by Molmil
Crystal Structure of Bradyrhizobium japonicum Proline Utilization A (PutA) Mutant D779W
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Proline dehydrogenase, ...
Authors:Tanner, J.J, Luo, M, Pemberton, T.A.
Deposit date:2014-04-23
Release date:2014-08-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Kinetic and Structural Characterization of Tunnel-Perturbing Mutants in Bradyrhizobium japonicum Proline Utilization A.
Biochemistry, 53, 2014
5UAW
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BU of 5uaw by Molmil
Structure of apo human PYCR-1 crystallized in space group P21212
Descriptor: Pyrroline-5-carboxylate reductase 1, mitochondrial, SULFATE ION
Authors:Tanner, J.J.
Deposit date:2016-12-20
Release date:2017-03-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Resolving the cofactor-binding site in the proline biosynthetic enzyme human pyrroline-5-carboxylate reductase 1.
J. Biol. Chem., 292, 2017
5UAT
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BU of 5uat by Molmil
Structure of human PYCR-1 complexed with NADPH
Descriptor: DI(HYDROXYETHYL)ETHER, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Pyrroline-5-carboxylate reductase 1, ...
Authors:Tanner, J.J.
Deposit date:2016-12-20
Release date:2017-03-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Resolving the cofactor-binding site in the proline biosynthetic enzyme human pyrroline-5-carboxylate reductase 1.
J. Biol. Chem., 292, 2017
5UAU
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BU of 5uau by Molmil
Structure of human PYCR-1 complexed with proline
Descriptor: PROLINE, Pyrroline-5-carboxylate reductase 1, mitochondrial, ...
Authors:Tanner, J.J.
Deposit date:2016-12-20
Release date:2017-03-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Resolving the cofactor-binding site in the proline biosynthetic enzyme human pyrroline-5-carboxylate reductase 1.
J. Biol. Chem., 292, 2017
5UAV
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BU of 5uav by Molmil
Structure of human PYCR-1 complexed with NADPH and L-tetrahydrofuroic acid
Descriptor: DI(HYDROXYETHYL)ETHER, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Pyrroline-5-carboxylate reductase 1, ...
Authors:Tanner, J.J.
Deposit date:2016-12-20
Release date:2017-03-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Resolving the cofactor-binding site in the proline biosynthetic enzyme human pyrroline-5-carboxylate reductase 1.
J. Biol. Chem., 292, 2017
5UAX
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BU of 5uax by Molmil
Structure of apo human PYCR-1 crystallized in space group C2
Descriptor: CHLORIDE ION, Pyrroline-5-carboxylate reductase 1, mitochondrial
Authors:Tanner, J.J.
Deposit date:2016-12-20
Release date:2017-03-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Resolving the cofactor-binding site in the proline biosynthetic enzyme human pyrroline-5-carboxylate reductase 1.
J. Biol. Chem., 292, 2017
5UR2
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BU of 5ur2 by Molmil
Crystal structure of proline utilization A (PutA) from Bdellovibrio bacteriovorus inactivated by N-propargylglycine
Descriptor: Bifunctional protein PutA, N-propargylglycine-modified flavin adenine dinucleotide
Authors:Tanner, J.J.
Deposit date:2017-02-09
Release date:2017-08-02
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Biophysical investigation of type A PutAs reveals a conserved core oligomeric structure.
FEBS J., 284, 2017
5UX5
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BU of 5ux5 by Molmil
Structure of Proline Utilization A (PutA) from Corynebacterium freiburgense
Descriptor: BIFUNCTIONAL PROTEIN Proline utilization A (PutA), FLAVIN-ADENINE DINUCLEOTIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Tanner, J.J.
Deposit date:2017-02-22
Release date:2017-04-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure and characterization of a class 3B proline utilization A: Ligand-induced dimerization and importance of the C-terminal domain for catalysis.
J. Biol. Chem., 292, 2017
5VWT
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BU of 5vwt by Molmil
Crystal structure of oxidized Aspergillus fumigatus UDP-galactopyranose mutase complexed with NADPH
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION, ...
Authors:Tanner, J.J.
Deposit date:2017-05-22
Release date:2017-05-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Identification of the NAD(P)H binding site of eukaryotic UDP-galactopyranose mutase.
J. Am. Chem. Soc., 134, 2012
5VWU
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BU of 5vwu by Molmil
Crystal structure of oxidized Aspergillus fumigatus UDP-galactopyranose mutase complexed with NADH
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ...
Authors:Tanner, J.J.
Deposit date:2017-05-22
Release date:2017-05-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Identification of the NAD(P)H binding site of eukaryotic UDP-galactopyranose mutase.
J. Am. Chem. Soc., 134, 2012
4E3X
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BU of 4e3x by Molmil
Crystal Structure of Mus musculus 1-pyrroline-5-carboxylate dehydrogenase cryoprotected in proline
Descriptor: 3,6,9,12,15,18-HEXAOXAICOSANE, Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial, ...
Authors:Tanner, J.J, Pemberton, T.A.
Deposit date:2012-03-10
Release date:2012-07-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Proline: Mother Nature's cryoprotectant applied to protein crystallography.
Acta Crystallogr.,Sect.D, 68, 2012
4E3W
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BU of 4e3w by Molmil
Crystal Structure Francisella tularensis histidine acid phosphatase cryoprotected with proline
Descriptor: Acid phosphatase, PROLINE, SULFATE ION
Authors:Tanner, J.J, Pemberton, T.A.
Deposit date:2012-03-10
Release date:2012-07-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Proline: Mother Nature's cryoprotectant applied to protein crystallography.
Acta Crystallogr.,Sect.D, 68, 2012
4E3V
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BU of 4e3v by Molmil
Crystal Structure of XYLOSE ISOMERASE FROM STREPTOMYCES RUBIGINOSUS Cryoprotected in Proline
Descriptor: MAGNESIUM ION, MANGANESE (II) ION, PROLINE, ...
Authors:Tanner, J.J, Pemberton, T.A.
Deposit date:2012-03-10
Release date:2012-07-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.503 Å)
Cite:Proline: Mother Nature's cryoprotectant applied to protein crystallography.
Acta Crystallogr.,Sect.D, 68, 2012
4E3U
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BU of 4e3u by Molmil
Crystal Structure of Hen Egg White Lysozyme Cryoprotected in Proline
Descriptor: CHLORIDE ION, Lysozyme C, PROLINE
Authors:Tanner, J.J, Pemberton, T.A.
Deposit date:2012-03-10
Release date:2012-07-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Proline: Mother Nature's cryoprotectant applied to protein crystallography.
Acta Crystallogr.,Sect.D, 68, 2012
6U2X
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BU of 6u2x by Molmil
Structure of ALDH7A1 mutant E399G complexed with NAD
Descriptor: Alpha-aminoadipic semialdehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Tanner, J.J, Korasick, D.A, Laciak, A.R.
Deposit date:2019-08-20
Release date:2019-11-06
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural analysis of pathogenic mutations targeting Glu427 of ALDH7A1, the hot spot residue of pyridoxine-dependent epilepsy.
J. Inherit. Metab. Dis., 43, 2020
6X0K
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BU of 6x0k by Molmil
Structure of dithionite-reduced SidA ornithine hydroxylase with the FAD "in" and complexed with L-ornithine
Descriptor: DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, L-ornithine, L-ornithine N(5)-monooxygenase
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2020-05-15
Release date:2020-08-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.231 Å)
Cite:Trapping conformational states of a flavin-dependent N -monooxygenase in crystallo reveals protein and flavin dynamics.
J.Biol.Chem., 295, 2020
6WPU
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BU of 6wpu by Molmil
Structure of S-allyl-L-cysteine S-oxygenase from Allium sativum
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Flavin-containing monooxygenase, SULFATE ION
Authors:Tanner, J.J, Campbell, A.C, Schuermann, J.P.
Deposit date:2020-04-27
Release date:2020-06-17
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.084 Å)
Cite:Structure and function of a flavin-dependent S-monooxygenase from garlic (Allium sativum).
J.Biol.Chem., 295, 2020
6X0H
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BU of 6x0h by Molmil
Structure of oxidized SidA ornithine hydroxylase with the FAD in the "out" conformation
Descriptor: ACETATE ION, CALCIUM ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2020-05-15
Release date:2020-08-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.087 Å)
Cite:Trapping conformational states of a flavin-dependent N -monooxygenase in crystallo reveals protein and flavin dynamics.
J.Biol.Chem., 295, 2020
6X0J
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BU of 6x0j by Molmil
Structure of reduced SidA ornithine hydroxylase with the FAD "in" and complexed with NADP and L-ornithine
Descriptor: DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, L-ornithine, L-ornithine N(5)-monooxygenase, ...
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2020-05-15
Release date:2020-08-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.335 Å)
Cite:Trapping conformational states of a flavin-dependent N -monooxygenase in crystallo reveals protein and flavin dynamics.
J.Biol.Chem., 295, 2020
6X0I
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BU of 6x0i by Molmil
Structure of oxidized SidA ornithine hydroxylase with the FAD "in" and complexed with NADP
Descriptor: ACETATE ION, CALCIUM ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2020-05-15
Release date:2020-08-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Trapping conformational states of a flavin-dependent N -monooxygenase in crystallo reveals protein and flavin dynamics.
J.Biol.Chem., 295, 2020
6X9B
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BU of 6x9b by Molmil
Structure of proline utilization A with cis-4-hydroxy-D-proline bound in the L-glutamate-gamma-semialdehyde dehydrogenase active site
Descriptor: (4R)-4-hydroxy-D-proline, Bifunctional protein PutA, DI(HYDROXYETHYL)ETHER, ...
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2020-06-02
Release date:2020-12-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Structural analysis of prolines and hydroxyprolines binding to the l-glutamate-gamma-semialdehyde dehydrogenase active site of bifunctional proline utilization A.
Arch.Biochem.Biophys., 698, 2020
6X9C
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BU of 6x9c by Molmil
Structure of proline utilization A with L-proline bound in the L-glutamate-gamma-semialdehyde dehydrogenase active site
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Bifunctional protein PutA, DI(HYDROXYETHYL)ETHER, ...
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2020-06-02
Release date:2020-12-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Structural analysis of prolines and hydroxyprolines binding to the l-glutamate-gamma-semialdehyde dehydrogenase active site of bifunctional proline utilization A.
Arch.Biochem.Biophys., 698, 2020
6X99
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BU of 6x99 by Molmil
Structure of proline utilization A with D-proline bound in the L-glutamate-gamma-semialdehyde dehydrogenase active site
Descriptor: Bifunctional protein PutA, D-PROLINE, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2020-06-02
Release date:2020-12-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Structural analysis of prolines and hydroxyprolines binding to the l-glutamate-gamma-semialdehyde dehydrogenase active site of bifunctional proline utilization A.
Arch.Biochem.Biophys., 698, 2020
6XOZ
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BU of 6xoz by Molmil
Structure of human PYCR1 complexed with L-tetrahydro-2-furoic acid
Descriptor: CHLORIDE ION, Pyrroline-5-carboxylate reductase 1, mitochondrial, ...
Authors:Tanner, J.J, Christensen, E.M.
Deposit date:2020-07-07
Release date:2020-11-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:In crystallo screening for proline analog inhibitors of the proline cycle enzyme PYCR1.
J.Biol.Chem., 295, 2020
1P7K
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BU of 1p7k by Molmil
Crystal structure of an anti-ssDNA antigen-binding fragment (Fab) bound to 4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid (HEPES)
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Schuermann, J.P, Henzl, M.T, Deutscher, S.L, Tanner, J.J.
Deposit date:2003-05-02
Release date:2004-05-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure of an anti-DNA fab complexed with a non-DNA ligand provides insights into cross-reactivity and molecular mimicry.
Proteins, 57, 2004

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