5UAU

Structure of human PYCR-1 complexed with proline

Summary for 5UAU

• Entry DOI: 10.2210/pdb5uau/pdb
• Related: 5UAT 5UAV 5UAW 5UAX
• Descriptor: Pyrroline-5-carboxylate reductase 1, mitochondrial, PROLINE, SULFATE ION, ... (4 entities in total)
• Functional Keywords: amino-acid biosynthesis, oxidoreductase, proline biosynthesis
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 5
• Total formula weight: 171751.33

Authors

Tanner, J.J. (deposition date: 2016-12-20, release date: 2017-03-15, Last modification date: 2023-10-04)

• Primary citation: Christensen, E.M.,Patel, S.M.,Korasick, D.A.,Campbell, A.C.,Krause, K.L.,Becker, D.F.,Tanner, J.J.; Resolving the cofactor-binding site in the proline biosynthetic enzyme human pyrroline-5-carboxylate reductase 1.; J. Biol. Chem., 292:7233-7243, 2017; PubMed: 28258219; DOI: 10.1074/jbc.M117.780288

Experimental method

X-RAY DIFFRACTION (1.9 Å)