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4H2F
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BU of 4h2f by Molmil
Human ecto-5'-nucleotidase (CD73): crystal form I (open) in complex with adenosine
Descriptor: 5'-nucleotidase, ADENOSINE, CALCIUM ION, ...
Authors:Straeter, N, Knapp, K.M, Zebisch, M, Pippel, J.
Deposit date:2012-09-12
Release date:2012-11-28
Last modified:2014-10-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structure of the Human Ecto-5'-Nucleotidase (CD73): Insights into the Regulation of Purinergic Signaling.
Structure, 20, 2012
4H2G
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BU of 4h2g by Molmil
Human ecto-5'-nucleotidase (CD73): crystal form II (open) in complex with adenosine
Descriptor: 5'-nucleotidase, ADENOSINE, CALCIUM ION, ...
Authors:Straeter, N, Knapp, K.M, Zebisch, M, Pippel, J.
Deposit date:2012-09-12
Release date:2012-11-28
Last modified:2012-12-26
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal Structure of the Human Ecto-5'-Nucleotidase (CD73): Insights into the Regulation of Purinergic Signaling.
Structure, 20, 2012
4WL0
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BU of 4wl0 by Molmil
Ligand-free structure of human platelet phosphofructokinase in an R-state, crystal form I
Descriptor: ATP-dependent 6-phosphofructokinase, platelet type, PHOSPHATE ION
Authors:Kloos, M, Strater, N.
Deposit date:2014-10-05
Release date:2015-06-03
Last modified:2018-08-01
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Crystal structure of human platelet phosphofructokinase-1 locked in an activated conformation.
Biochem.J., 469, 2015
5JIW
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BU of 5jiw by Molmil
Crystal structure of Thermus aquaticus amylomaltase (GH77) in complex with a 34-meric cycloamylose
Descriptor: 1,2-ETHANEDIOL, 4-alpha-glucanotransferase, CARBONATE ION, ...
Authors:Roth, C, Bexten, N, Weizenmann, N, Saenger, T, Maier, T, Zimmermann, W, Straeter, N.
Deposit date:2016-04-22
Release date:2017-01-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Amylose recognition and ring-size determination of amylomaltase.
Sci Adv, 3, 2017
8B55
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BU of 8b55 by Molmil
Human ADGRG4 PTX-like domain
Descriptor: Adhesion G-protein coupled receptor G4, MAGNESIUM ION
Authors:Kieslich, B, Straeter, N.
Deposit date:2022-09-21
Release date:2022-10-19
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:The dimerized pentraxin-like domain of the adhesion G protein-coupled receptor 112 (ADGRG4) suggests function in sensing mechanical forces.
J.Biol.Chem., 299, 2023
4XZ2
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BU of 4xz2 by Molmil
Human platelet phosphofructokinase in an R-state in complex with ADP and F6P, crystal form I
Descriptor: 1,6-di-O-phosphono-beta-D-fructofuranose, 6-O-phosphono-beta-D-fructofuranose, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Kloos, M, Strater, N.
Deposit date:2015-02-03
Release date:2015-06-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Crystal structure of human platelet phosphofructokinase-1 locked in an activated conformation.
Biochem.J., 469, 2015
8BF2
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BU of 8bf2 by Molmil
Human PPARgamma in complex with MEHP bound to the AF-2 and omega sub-pockets
Descriptor: 2-[(2~{S})-2-ethylhexoxy]carbonylbenzoic acid, Peroxisome proliferator-activated receptor gamma
Authors:Useini, A, Straeter, N.
Deposit date:2022-10-23
Release date:2023-03-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Structural basis of the activation of PPAR gamma by the plasticizer metabolites MEHP and MINCH.
Environ Int, 173, 2023
8BF1
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BU of 8bf1 by Molmil
High-resolution structure of unliganded PPAR gamma in complex with the peptide PGC-1 alpha
Descriptor: Peroxisome proliferator-activated receptor gamma, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
Authors:Useini, A, Straeter, N.
Deposit date:2022-10-23
Release date:2023-03-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Structural basis of the activation of PPAR gamma by the plasticizer metabolites MEHP and MINCH.
Environ Int, 173, 2023
8BFF
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BU of 8bff by Molmil
Human PPARgamma in complex with MINCH bound to the AF-2 sub-pocket
Descriptor: (1~{S},2~{R})-2-[(4~{R})-4-methylheptoxy]carbonylcyclohexane-1-carboxylic acid, Peroxisome proliferator-activated receptor gamma
Authors:Useini, A, Straeter, N.
Deposit date:2022-10-25
Release date:2023-03-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis of the activation of PPAR gamma by the plasticizer metabolites MEHP and MINCH.
Environ Int, 173, 2023
4R3U
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BU of 4r3u by Molmil
Crystal structure of 2-Hydroxyisobutyryl-CoA Mutase
Descriptor: 2-hydroxyisobutyryl-CoA mutase large subunit, 2-hydroxyisobutyryl-CoA mutase small subunit, 3-HYDROXYBUTANOYL-COENZYME A, ...
Authors:Zahn, M, Kurteva-Yaneva, N, Rohwerder, T, Straeter, N.
Deposit date:2014-08-18
Release date:2015-03-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of the stereospecificity of bacterial B12-dependent 2-hydroxyisobutyryl-CoA mutase.
J.Biol.Chem., 290, 2015
1CWY
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BU of 1cwy by Molmil
CRYSTAL STRUCTURE OF AMYLOMALTASE FROM THERMUS AQUATICUS, A GLYCOSYLTRANSFERASE CATALYSING THE PRODUCTION OF LARGE CYCLIC GLUCANS
Descriptor: AMYLOMALTASE
Authors:Przylas, I, Tomoo, K, Terada, Y, Takaha, T, Fuji, K, Saenger, W, Straeter, N.
Deposit date:1999-08-27
Release date:2001-02-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of amylomaltase from thermus aquaticus, a glycosyltransferase catalysing the production of large cyclic glucans.
J.Mol.Biol., 296, 2000
1ESW
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BU of 1esw by Molmil
X-RAY STRUCTURE OF ACARBOSE BOUND TO AMYLOMALTASE FROM THERMUS AQUATICUS. IMPLICATIONS FOR THE SYNTHESIS OF LARGE CYCLIC GLUCANS
Descriptor: 1,2-ETHANEDIOL, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, AMYLOMALTASE
Authors:Przylas, I, Terada, Y, Fujii, K, Takaha, T, Saenger, W, Straeter, N.
Deposit date:2000-04-11
Release date:2001-04-11
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-ray structure of acarbose bound to amylomaltase from Thermus aquaticus. Implications for the synthesis of large cyclic glucans.
Eur.J.Biochem., 267, 2000
1GVN
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BU of 1gvn by Molmil
Crystal Structure of the Plasmid Maintenance System epsilon/zeta: Meachnism of toxin inactivation and toxin function
Descriptor: EPSILON, SULFATE ION, ZETA
Authors:Meinhart, A, Alonso, J.C, Straeter, N, Saenger, W.
Deposit date:2002-02-19
Release date:2003-01-29
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal Structure of the Plasmid Maintenance System Epsilon /Zeta : Functional Mechanism of Toxin Zeta and Inactivation by Epsilon 2 Zeta 2 Complex Formation
Proc.Natl.Acad.Sci.USA, 100, 2003
6SJU
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BU of 6sju by Molmil
Human kallikrein 7 with aromatic coumarinic ester compound 3 covalently bound to H57
Descriptor: (3-iodanylphenyl) 6-methyl-2-oxidanylidene-chromene-3-carboxylate, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Kallikrein-7, ...
Authors:Hanke, S, Straeter, N.
Deposit date:2019-08-13
Release date:2020-05-20
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structural Studies on the Inhibitory Binding Mode of Aromatic Coumarinic Esters to Human Kallikrein-Related Peptidase 7.
J.Med.Chem., 63, 2020
6SHI
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BU of 6shi by Molmil
Human kallikrein 7 with aromatic coumarinic ester compound 2 covalently bound to H57
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 6-methyl-2-oxidanylidene-chromene-3-carboxylic acid, Kallikrein-7, ...
Authors:Hanke, S, Straeter, N.
Deposit date:2019-08-06
Release date:2020-05-20
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural Studies on the Inhibitory Binding Mode of Aromatic Coumarinic Esters to Human Kallikrein-Related Peptidase 7.
J.Med.Chem., 63, 2020
6SHH
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BU of 6shh by Molmil
Human kallikrein 7 with aromatic coumarinic ester compound 1 covalently bound to H57
Descriptor: (3-chlorophenyl) 6-methyl-2-oxidanylidene-chromene-3-carboxylate, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Kallikrein-7, ...
Authors:Hanke, S, Straeter, N.
Deposit date:2019-08-06
Release date:2020-05-20
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Studies on the Inhibitory Binding Mode of Aromatic Coumarinic Esters to Human Kallikrein-Related Peptidase 7.
J.Med.Chem., 63, 2020
3QNJ
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BU of 3qnj by Molmil
Crystal structure of the substrate binding domain of E.coli DnaK in complex with the antimicrobial peptide oncocin
Descriptor: Chaperone protein DnaK, SULFATE ION, antimicrobial peptide oncocin
Authors:Zahn, M, Straeter, N.
Deposit date:2011-02-08
Release date:2011-03-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Rational Design of Oncocin Derivatives with Superior Protease Stabilities and Antibacterial Activities Based on the High-Resolution Structure of the Oncocin-DnaK Complex.
Chembiochem, 12, 2011
4OMT
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BU of 4omt by Molmil
Crystal structure of human muscle phosphofructokinase (dissociated homodimer)
Descriptor: 6-phosphofructokinase, muscle type
Authors:Kloos, M, Straeter, N.
Deposit date:2014-01-27
Release date:2014-05-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (6 Å)
Cite:Crystallization and preliminary crystallographic analysis of human muscle phosphofructokinase, the main regulator of glycolysis.
Acta Crystallogr F Struct Biol Commun, 70, 2014
1Q9E
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BU of 1q9e by Molmil
RNase T1 variant with adenine specificity
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Guanyl-specific ribonuclease T1 precursor
Authors:Czaja, R, Struhalla, M, Hoeschler, K, Saenger, W, Straeter, N, Hahn, U.
Deposit date:2003-08-25
Release date:2004-03-23
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:RNase T1 Variant RV Cleaves Single-Stranded RNA after Purines Due to Specific Recognition by the Asn46 Side Chain Amide.
Biochemistry, 43, 2004
2BJ6
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BU of 2bj6 by Molmil
Crystal Structure of a decameric HNA-RNA hybrid
Descriptor: 5'-R(*GP*GP*CP*AP*UP*UP*AP*CP*GP*GP)-3', SULFATE ION, SYNTHETIC HNA
Authors:Maier, T, Przylas, I, Straeter, N, Herdewijn, P, Saenger, W.
Deposit date:2005-01-30
Release date:2005-03-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Reinforced Hna Backbone Hydration in the Crystal Structure of a Decameric Hna/RNA Hybrid
J.Am.Chem.Soc., 127, 2005
4E81
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BU of 4e81 by Molmil
Crystal structure of the substrate binding domain of E.coli DnaK in complex with a short apidaecin peptide
Descriptor: Chaperone protein DnaK, SULFATE ION, apidaecin peptide fragment
Authors:Zahn, M, Straeter, N.
Deposit date:2012-03-19
Release date:2012-05-30
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Api88 is a novel antibacterial designer Peptide to treat systemic infections with multidrug-resistant gram-negative pathogens.
Acs Chem.Biol., 7, 2012
4EZP
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BU of 4ezp by Molmil
Crystal structure of the substrate binding domain of E.coli DnaK in complex with A3-APO(residues 1 to 20)
Descriptor: APO-monomer, Chaperone protein DnaK, SULFATE ION
Authors:Zahn, M, Straeter, N.
Deposit date:2012-05-03
Release date:2013-04-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK.
J.Mol.Biol., 425, 2013
4F01
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BU of 4f01 by Molmil
Crystal structure of an artificial dimeric DnaK complex
Descriptor: Chaperone protein DnaK
Authors:Zahn, M, Straeter, N.
Deposit date:2012-05-03
Release date:2013-04-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK.
J.Mol.Biol., 425, 2013
4EZT
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BU of 4ezt by Molmil
Crystal structure of the substrate binding domain of E.coli DnaK in complex with heliocin (residues 14 to 21)
Descriptor: Chaperone protein DnaK, Heliocin
Authors:Zahn, M, Straeter, N.
Deposit date:2012-05-03
Release date:2013-04-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK.
J.Mol.Biol., 425, 2013
4EZR
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BU of 4ezr by Molmil
Crystal structure of the substrate binding domain of E.coli DnaK in complex with the C-terminal part of drosocin (residues 12 to 19)
Descriptor: Chaperone protein DnaK, Drosocin
Authors:Zahn, M, Straeter, N.
Deposit date:2012-05-03
Release date:2013-04-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK.
J.Mol.Biol., 425, 2013

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