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5IPM
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BU of 5ipm by Molmil
SigmaS-transcription initiation complex with 4-nt nascent RNA
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Liu, B, Zuo, Y, Steitz, T.A.
登録日2016-03-09
公開日2016-03-30
最終更新日2016-06-22
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Structures of E. coli sigma S-transcription initiation complexes provide new insights into polymerase mechanism.
Proc.Natl.Acad.Sci.USA, 113, 2016
5J4C
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BU of 5j4c by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with cisplatin (soaked) and bound to mRNA and A-, P- and E-site tRNAs at 2.8A resolution
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Melnikov, S.V, Soll, D, Steitz, T.A, Polikanov, Y.S.
登録日2016-03-31
公開日2016-04-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Insights into RNA binding by the anticancer drug cisplatin from the crystal structure of cisplatin-modified ribosome.
Nucleic Acids Res., 44, 2016
5J8B
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BU of 5j8b by Molmil
Crystal structure of Elongation Factor 4 (EF-4/LepA) in complex with GDPCP bound to the Thermus thermophilus 70S ribosome
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Gagnon, M.G, Lin, J, Steitz, T.A.
登録日2016-04-07
公開日2016-05-25
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Elongation factor 4 remodels the A-site tRNA on the ribosome.
Proc.Natl.Acad.Sci.USA, 113, 2016
5DOX
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BU of 5dox by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with Hygromycin-A at 3.1A resolution
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Polikanov, Y.S, Starosta, A.L, Juette, M.F, Altman, R.B, Terry, D.S, Lu, W, Burnett, B.J, Dinos, G, Reynolds, K, Blanchard, S.C, Steitz, T.A, Wilson, D.N.
登録日2015-09-11
公開日2015-12-30
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A.
Mol.Cell, 58, 2015
5J4B
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BU of 5j4b by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with cisplatin (co-crystallized) and bound to mRNA and A-, P- and E-site tRNAs at 2.6A resolution
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Melnikov, S.V, Soll, D, Steitz, T.A, Polikanov, Y.S.
登録日2016-03-31
公開日2016-04-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Insights into RNA binding by the anticancer drug cisplatin from the crystal structure of cisplatin-modified ribosome.
Nucleic Acids Res., 44, 2016
5DOY
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BU of 5doy by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with antibiotic Hygromycin A, mRNA and three tRNAs in the A, P and E sites at 2.6A resolution
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
著者Polikanov, Y.S, Starosta, A.L, Juette, M.F, Altman, R.B, Terry, D.S, Lu, W, Burnett, B.J, Dinos, G, Reynolds, K, Blanchard, S.C, Steitz, T.A, Wilson, D.N.
登録日2015-09-11
公開日2015-12-30
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A.
Mol.Cell, 58, 2015
4JKR
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BU of 4jkr by Molmil
Crystal Structure of E. coli RNA Polymerase in complex with ppGpp
分子名称: DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA', DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Zuo, Y, Wang, Y, Steitz, T.A.
登録日2013-03-11
公開日2013-05-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献The mechanism of E. coli RNA polymerase regulation by ppGpp is suggested by the structure of their complex.
Mol.Cell, 50, 2013
4KJZ
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BU of 4kjz by Molmil
Crystal Structure of Thermus Thermophilus IF2, Apo and GDP-bound Forms (2-474)
分子名称: GUANOSINE-5'-DIPHOSPHATE, Translation initiation factor IF-2
著者Eiler, D.R, Lin, J, Steitz, T.A.
登録日2013-05-04
公開日2013-09-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Initiation factor 2 crystal structure reveals a different domain organization from eukaryotic initiation factor 5B and mechanism among translational GTPases.
Proc.Natl.Acad.Sci.USA, 110, 2013
4KZX
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BU of 4kzx by Molmil
Rabbit 40S ribosomal subunit in complex with eIF1.
分子名称: 18S ribosomal RNA, 40S Ribosomal protein S9, 40S ribosomal protein RACK1, ...
著者Lomakin, I.B, Steitz, T.A.
登録日2013-05-30
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (7.809 Å)
主引用文献The initiation of mammalian protein synthesis and mRNA scanning mechanism.
Nature, 500, 2013
4KZY
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BU of 4kzy by Molmil
Rabbit 40S ribosomal subunit in complex with eIF1 and eIF1A.
分子名称: 18S Ribosomal RNA, 40S Ribosomal Protein RACK1, 40S Ribosomal Protein S10, ...
著者Lomakin, I.B, Steitz, T.A.
登録日2013-05-30
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (7.01 Å)
主引用文献The initiation of mammalian protein synthesis and mRNA scanning mechanism.
Nature, 500, 2013
4KZZ
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BU of 4kzz by Molmil
Rabbit 40S ribosomal subunit in complex with mRNA, initiator tRNA and eIF1A
分子名称: 18S Ribosomal RNA, 40S Ribosomal Protein RACK1, 40S Ribosomal Protein S10, ...
著者Lomakin, I.B, Steitz, T.A.
登録日2013-05-30
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (7.0305 Å)
主引用文献The initiation of mammalian protein synthesis and mRNA scanning mechanism.
Nature, 500, 2013
4M6F
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BU of 4m6f by Molmil
Dimer of the G-Segment Invertase bound to a DNA substrate
分子名称: DNA-invertase, gix site analog
著者Ritacco, C.J, Wang, J, Steitz, T.A.
登録日2013-08-09
公開日2014-03-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (4.99 Å)
主引用文献Exploiting large non-isomorphous differences for phase determination of a G-segment invertase-DNA complex.
Acta Crystallogr.,Sect.D, 70, 2014
4M4W
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BU of 4m4w by Molmil
Mechanistic implications for the bacterial primosome assembly of the structure of a helicase-helicase loader complex
分子名称: DNA primase, Primosomal protein DnaI, Replicative helicase
著者Liu, B, Eliason, W.K, Steitz, T.A.
登録日2013-08-07
公開日2013-09-25
最終更新日2013-10-02
実験手法X-RAY DIFFRACTION (6.1 Å)
主引用文献Structure of a helicase-helicase loader complex reveals insights into the mechanism of bacterial primosome assembly.
Nat Commun, 4, 2013
4V8A
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BU of 4v8a by Molmil
The structure of thermorubin in complex with the 70S ribosome from Thermus thermophilus.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Bulkley, D, Johnson, F.A, Steitz, T.A.
登録日2011-12-05
公開日2014-07-09
最終更新日2014-12-10
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The antibiotic thermorubin inhibits protein synthesis by binding to inter-subunit bridge b2a of the ribosome.
J.Mol.Biol., 416, 2012
4W2E
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BU of 4w2e by Molmil
Crystal structure of Elongation Factor 4 (EF4/LepA) bound to the Thermus thermophilus 70S ribosome
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Gagnon, M.G, Lin, J, Steitz, T.A.
登録日2014-06-04
公開日2014-10-01
最終更新日2023-07-26
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of elongation factor 4 bound to a clockwise ratcheted ribosome.
Science, 345, 2014
4V7Z
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BU of 4v7z by Molmil
Structure of the Thermus thermophilus 70S ribosome complexed with telithromycin.
分子名称: 16S rRNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Bulkley, D.P, Innis, C.A, Blaha, G, Steitz, T.A.
登録日2010-08-18
公開日2014-07-09
最終更新日2021-01-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Revisiting the structures of several antibiotics bound to the bacterial ribosome.
Proc.Natl.Acad.Sci.USA, 107, 2010
4WQF
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BU of 4wqf by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with elongation factor G and fusidic acid in the post-translocational state
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Lin, J, Gagnon, M.G, Steitz, T.A.
登録日2014-10-21
公開日2015-01-28
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Conformational Changes of Elongation Factor G on the Ribosome during tRNA Translocation.
Cell, 160, 2015
4WPO
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BU of 4wpo by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with elongation factor G in the pre-translocational state
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Lin, J, Gagnon, M.G, Steitz, T.A.
登録日2014-10-20
公開日2015-01-28
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Conformational Changes of Elongation Factor G on the Ribosome during tRNA Translocation.
Cell, 160, 2015
1FG0
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BU of 1fg0 by Molmil
LARGE RIBOSOMAL SUBUNIT COMPLEXED WITH A 13 BP MINIHELIX-PUROMYCIN COMPOUND
分子名称: 23S RIBOSOMAL RNA, 5'-R(CCGGCGGGCUGGUUCAAACCGGCCCGCCGGACC)-3'-5'-R(P-PUROMYCIN)-3'
著者Nissen, P, Hansen, J, Ban, N, Moore, P.B, Steitz, T.A.
登録日2000-07-26
公開日2000-08-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The structural basis of ribosome activity in peptide bond synthesis.
Science, 289, 2000
4WQU
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BU of 4wqu by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with elongation factor G trapped by the antibiotic dityromycin
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Lin, J, Gagnon, M.G, Steitz, T.A.
登録日2014-10-22
公開日2015-01-28
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Conformational Changes of Elongation Factor G on the Ribosome during tRNA Translocation.
Cell, 160, 2015
1FFZ
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BU of 1ffz by Molmil
LARGE RIBOSOMAL SUBUNIT COMPLEXED WITH R(CC)-DA-PUROMYCIN
分子名称: 23S RIBOSOMAL RNA, R(P*CP*C*)-D(P*A)-R(P*(PU))
著者Nissen, P, Hansen, J, Ban, N, Moore, P.B, Steitz, T.A.
登録日2000-07-26
公開日2000-08-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The structural basis of ribosome activity in peptide bond synthesis.
Science, 289, 2000
4WQY
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BU of 4wqy by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with elongation factor G in the post-translocational state (without fusitic acid)
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Lin, J, Gagnon, M.G, Steitz, T.A.
登録日2014-10-22
公開日2015-01-28
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Conformational Changes of Elongation Factor G on the Ribosome during tRNA Translocation.
Cell, 160, 2015
4Y4O
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BU of 4y4o by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome with rRNA modifications and bound to protein Y (YfiA) at 2.3A resolution
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ...
著者Polikanov, Y.S, Melnikov, S.V, Soll, D, Steitz, T.A.
登録日2015-02-10
公開日2015-03-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly.
Nat.Struct.Mol.Biol., 22, 2015
4YLP
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BU of 4ylp by Molmil
E. coli Transcription Initiation Complex - 16-bp spacer and 5-nt RNA
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Zuo, Y, Steitz, T.A.
登録日2015-03-05
公開日2015-04-22
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (5.5 Å)
主引用文献Crystal Structures of the E. coli Transcription Initiation Complexes with a Complete Bubble.
Mol.Cell, 58, 2015
1GSG
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BU of 1gsg by Molmil
Structure of E.coli glutaminyl-tRNA synthetase complexed with trnagln and ATP at 2.8 Angstroms resolution
分子名称: GLUTAMINYL-TRNA SYNTHETASE, TRNAGLN
著者Rould, M.A, Perona, J.J, Soell, D, Steitz, T.A.
登録日1990-04-03
公開日1992-02-24
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of E. coli glutaminyl-tRNA synthetase complexed with tRNA(Gln) and ATP at 2.8 A resolution.
Science, 246, 1989

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