6QNO
 
 | | Rhodopsin-Gi protein complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab antibody fragment heavy chain, Fab antibody fragment light chain, ... | | 著者 | Tsai, C.-J, Marino, J, Adaixo, R.J, Pamula, F, Muehle, J, Maeda, S, Flock, T, Taylor, N.M.I, Mohammed, I, Matile, H, Dawson, R.J.P, Deupi, X, Stahlberg, H, Schertler, G.F.X. | | 登録日 | 2019-02-11 | | 公開日 | 2019-07-10 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (4.38 Å) | | 主引用文献 | Cryo-EM structure of the rhodopsin-G alpha i-beta gamma complex reveals binding of the rhodopsin C-terminal tail to the G beta subunit.
Elife, 8, 2019
|
|
6H6B
 | | Structure of alpha-synuclein fibrils | | 分子名称: | Alpha-synuclein | | 著者 | Guerrero-Ferreira, R, Taylor, N.M.I, Mona, D, Ringler, P, Lauer, M.E, Riek, R, Britschgi, M, Stahlberg, H. | | 登録日 | 2018-07-26 | | 公開日 | 2018-08-08 | | 最終更新日 | 2023-02-22 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryo-EM structure of alpha-synuclein fibrils.
Elife, 7, 2018
|
|
6I9D
 | | MloK1 consensus structure from single particle analysis of 2D crystals | | 分子名称: | Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION | | 著者 | Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H. | | 登録日 | 2018-11-23 | | 公開日 | 2019-04-24 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019
|
|
6IAX
 | | MloK1 model from single particle analysis of 2D crystals, class 1 (extended conformation) | | 分子名称: | Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION | | 著者 | Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H. | | 登録日 | 2018-11-27 | | 公開日 | 2019-04-24 | | 実験手法 | ELECTRON MICROSCOPY (5.2 Å) | | 主引用文献 | Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019
|
|
6HZM
 | | Cryo-EM structure of the ABCG2 E211Q mutant bound to ATP and Magnesium (alternative placement of Magnesium into the cryo-EM density) | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family G member 2, MAGNESIUM ION | | 著者 | Manolaridis, I, Jackson, S.M, Taylor, N.M.I, Kowal, J, Stahlberg, H, Locher, K.P. | | 登録日 | 2018-10-23 | | 公開日 | 2018-11-14 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | | 主引用文献 | Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states.
Nature, 563, 2018
|
|
6HIJ
 | | Cryo-EM structure of the human ABCG2-MZ29-Fab complex with cholesterol and PE lipids docked | | 分子名称: | 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, ATP-binding cassette sub-family G member 2, CHOLESTEROL, ... | | 著者 | Jackson, S.M, Manolaridis, I, Kowal, J, Zechner, M, Taylor, N.M.I, Bause, M, Bauer, S, Bartholomaeus, R, Stahlberg, H, Bernhardt, G, Koenig, B, Buschauer, A, Altmann, K.H, Locher, K.P. | | 登録日 | 2018-08-30 | | 公開日 | 2018-09-19 | | 最終更新日 | 2019-12-11 | | 実験手法 | ELECTRON MICROSCOPY (3.56 Å) | | 主引用文献 | Structural basis of small-molecule inhibition of human multidrug transporter ABCG2.
Nat.Struct.Mol.Biol., 25, 2018
|
|
6HBU
 | | Cryo-EM structure of the ABCG2 E211Q mutant bound to ATP and Magnesium | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family G member 2, MAGNESIUM ION | | 著者 | Manolaridis, I, Jackson, S.M, Taylor, N.M.I, Kowal, J, Stahlberg, H, Locher, K.P. | | 登録日 | 2018-08-13 | | 公開日 | 2018-11-07 | | 最終更新日 | 2019-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | | 主引用文献 | Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states.
Nature, 563, 2018
|
|
6HCO
 | | Cryo-EM structure of the ABCG2 E211Q mutant bound to estrone 3-sulfate and 5D3-Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3-Fab heavy chain, 5D3-Fab light chain, ... | | 著者 | Manolaridis, I, Jackson, S.M, Taylor, N.M.I, Kowal, J, Stahlberg, H, Locher, K.P. | | 登録日 | 2018-08-15 | | 公開日 | 2018-11-07 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.58 Å) | | 主引用文献 | Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states.
Nature, 563, 2018
|
|
8OZD
 | | cryoEM structure of SPARTA complex dimer-3 | | 分子名称: | DNA (16-MER), Piwi domain-containing protein, RNA (18-MER), ... | | 著者 | Ekundayo, B, Ni, D.C, Lu, X.H, Stahlberg, H. | | 登録日 | 2023-05-09 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-08-23 | | 実験手法 | ELECTRON MICROSCOPY (3.89 Å) | | 主引用文献 | Activation mechanism of a short argonaute-TIR prokaryotic immune system.
Sci Adv, 9, 2023
|
|
8OZC
 | | cryoEM structure of SPARTA complex heterodimer apo | | 分子名称: | Piwi domain-containing protein, TIR domain-containing protein | | 著者 | Ekundayo, B, Ni, D.C, Lu, X.H, Stahlberg, H. | | 登録日 | 2023-05-09 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-08-23 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Activation mechanism of a short argonaute-TIR prokaryotic immune system.
Sci Adv, 9, 2023
|
|
5NJ3
 | | Structure of an ABC transporter: complete structure | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3-Fab heavy chain, 5D3-Fab light chain, ... | | 著者 | Taylor, N.M.I, Manolaridis, I, Jackson, S.M, Kowal, J, Stahlberg, H, Locher, K.P. | | 登録日 | 2017-03-28 | | 公開日 | 2017-06-07 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.78 Å) | | 主引用文献 | Structure of the human multidrug transporter ABCG2.
Nature, 546, 2017
|
|
5MXN
 | | Atomic model of the VipA/VipB/Hcp, the type six secretion system non-contractile sheath-tube of Vibrio cholerae from cryo-EM | | 分子名称: | Haemolysin co-regulated protein, Type VI secretion protein | | 著者 | Wang, J, Brackmann, M, Castano-Diez, D, Kudryashev, M, Goldie, K, Maier, T, Stahlberg, H, Basler, M. | | 登録日 | 2017-01-23 | | 公開日 | 2017-08-02 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Cryo-EM structure of the extended type VI secretion system sheath-tube complex.
Nat Microbiol, 2, 2017
|
|
8RQB
 | |
8RFE
 | | CgsiGP2 sample in nanodisc | | 分子名称: | Cyclic beta 1-2 glucan synthetase, URIDINE-5'-DIPHOSPHATE-GLUCOSE, beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose | | 著者 | Sedzicki, J, Ni, D, Lehmann, F, Stahlberg, H, Dehio, C. | | 登録日 | 2023-12-12 | | 公開日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structure-function analysis of the cyclic beta-1,2-glucan synthase from Agrobacterium tumefaciens.
Nat Commun, 15, 2024
|
|
8RFG
 | | CgsiGP3 sample in nanodisc | | 分子名称: | Cyclic beta 1-2 glucan synthetase, beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose, beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose, ... | | 著者 | Sedzicki, J, Ni, D, Lehmann, F, Stahlberg, H, Dehio, C. | | 登録日 | 2023-12-12 | | 公開日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | | 主引用文献 | Structure-function analysis of the cyclic beta-1,2-glucan synthase from Agrobacterium tumefaciens.
Nat Commun, 15, 2024
|
|
8RF0
 | | WT-CGS sample in nanodisc | | 分子名称: | Cyclic beta-(1,2)-glucan synthase NdvB, URIDINE-5'-DIPHOSPHATE-GLUCOSE, beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose, ... | | 著者 | Sedzicki, J, Ni, D, Lehmann, F, Stahlberg, H, Dehio, C. | | 登録日 | 2023-12-12 | | 公開日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure-function analysis of the cyclic beta-1,2-glucan synthase from Agrobacterium tumefaciens.
Nat Commun, 15, 2024
|
|
5NE0
 | | Room temperature in-situ structure of hen egg-white lysozyme from crystals enclosed between ultrathin silicon nitride membranes | | 分子名称: | CHLORIDE ION, Lysozyme C, SODIUM ION | | 著者 | Martiel, I, Opara, N, Arnold, S.A, Braun, T, Stahlberg, H, Makita, M, David, C, Padeste, C. | | 登録日 | 2017-03-09 | | 公開日 | 2017-06-14 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | Direct protein crystallization on ultrathin membranes for diffraction measurements at X-ray free-electron lasers.
J.Appl.Crystallogr., 50, 2017
|
|
5NJG
 | | Structure of an ABC transporter: part of the structure that could be built de novo | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3-Fab heavy chain, 5D3-Fab light chain, ... | | 著者 | Taylor, N.M.I, Manolaridis, I, Jackson, S.M, Kowal, J, Stahlberg, H, Locher, K.P. | | 登録日 | 2017-03-28 | | 公開日 | 2017-06-07 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.78 Å) | | 主引用文献 | Structure of the human multidrug transporter ABCG2.
Nature, 546, 2017
|
|
5MYU
 | | VipA-N2/VipB contracted sheath of type VI secretion system | | 分子名称: | Type VI secretion system protein ImpC, Uncharacterized protein | | 著者 | Wang, J, Brackmann, B, Castano-Diez, D, Kudryashev, M, Goldie, D, Maier, T, Stahlberg, H, Basler, M. | | 登録日 | 2017-01-27 | | 公開日 | 2017-08-02 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Cryo-EM structure of the extended type VI secretion system sheath-tube complex.
Nat Microbiol, 2, 2017
|
|
8PM6
 | | Human bile salt export pump (BSEP) in complex with inhibitor GBM in nanodiscs | | 分子名称: | 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, Bile salt export pump, CHOLESTEROL | | 著者 | Liu, H, Irobalieva, R.N, Kowal, J, Ni, D, Nosol, K, Bang-Sorensen, R, Lancien, L, Stahlberg, H, Stieger, B, Locher, K.P. | | 登録日 | 2023-06-28 | | 公開日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | | 主引用文献 | Structural basis of bile salt extrusion and small-molecule inhibition in human BSEP.
Nat Commun, 14, 2023
|
|
8PMJ
 | | Vanadate-trapped BSEP in nanodiscs | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Bile salt export pump, ... | | 著者 | Liu, H, Irobalieva, R.N, Kowal, J, Ni, D, Nosol, K, Bang-Sorensen, R, Lancien, L, Stahlberg, H, Stieger, B, Locher, K.P. | | 登録日 | 2023-06-28 | | 公開日 | 2023-11-29 | | 実験手法 | ELECTRON MICROSCOPY (2.81 Å) | | 主引用文献 | Structural basis of bile salt extrusion and small-molecule inhibition in human BSEP.
Nat Commun, 14, 2023
|
|
8PMD
 | | Nucleotide-bound BSEP in nanodiscs | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Bile salt export pump, MAGNESIUM ION | | 著者 | Liu, H, Irobalieva, R.N, Kowal, J, Ni, D, Nosol, K, Bang-Sorensen, R, Lancien, L, Stahlberg, H, Stieger, B, Locher, K.P. | | 登録日 | 2023-06-28 | | 公開日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | | 主引用文献 | Structural basis of bile salt extrusion and small-molecule inhibition in human BSEP.
Nat Commun, 14, 2023
|
|
5OJQ
 | | The modeled structure of of wild type extended type VI secretion system sheath/tube complex in vibrio cholerae based on cryo-EM reconstruction of the non-contractile sheath/tube complex | | 分子名称: | Haemolysin co-regulated protein, Type VI secretion protein, VipA | | 著者 | Wang, J, Brackmann, M, Castano-Diez, D, Kudryashev, M, Goldie, K, Maier, T, Stahlberg, H, Basler, M. | | 登録日 | 2017-07-22 | | 公開日 | 2017-08-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Cryo-EM structure of the extended type VI secretion system sheath-tube complex.
Nat Microbiol, 2, 2017
|
|
6R70
 | | Endogeneous native human 20S proteasome | | 分子名称: | Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ... | | 著者 | Schmidli, C, Albiez, S, Rima, L, Righetto, R, Mohammed, I, Oliva, P, Kovacik, L, Stahlberg, H, Braun, T. | | 登録日 | 2019-03-28 | | 公開日 | 2019-07-03 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Microfluidic protein isolation and sample preparation for high-resolution cryo-EM.
Proc.Natl.Acad.Sci.USA, 116, 2019
|
|
6R7M
 | | Tobacco Mosaic Virus (TMV) | | 分子名称: | Capsid protein | | 著者 | Schmidli, C, Albiez, S, Rima, L, Righetto, R, Mohammed, I, Oliva, P, Kovacik, L, Stahlberg, H, Braun, T. | | 登録日 | 2019-03-29 | | 公開日 | 2019-07-03 | | 最終更新日 | 2019-11-27 | | 実験手法 | ELECTRON MICROSCOPY (1.92 Å) | | 主引用文献 | Microfluidic protein isolation and sample preparation for high-resolution cryo-EM.
Proc.Natl.Acad.Sci.USA, 116, 2019
|
|
