8TKO
 
 | | KS-AT core of 6-deoxyerythronolide B synthase (DEBS) Module 3 crosslinked with its translocation ACP partner of Module 2 | | Descriptor: | EryAI, EryAII | | Authors: | Cogan, D.P, Soohoo, A.M, Chen, M, Brodsky, K.L, Liu, Y, Khosla, C. | | Deposit date: | 2023-07-25 | | Release date: | 2024-07-31 | | Last modified: | 2024-09-04 | | Method: | ELECTRON MICROSCOPY (3.05 Å) | | Cite: | Structural basis for intermodular communication in assembly-line polyketide biosynthesis.
Nat.Chem.Biol., 2024
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8TJO
 | | Crosslinked 6-deoxyerythronolide B synthase (DEBS) Module 1 in complex with antibody fragment 1B2: Crosslinked Intra-State 1 | | Descriptor: | Antibody Fragment 1B2, Heavy Chain, Light Chain, ... | | Authors: | Cogan, D.P, Soohoo, A.M, Chen, M, Brodsky, K.L, Liu, Y, Khosla, C. | | Deposit date: | 2023-07-23 | | Release date: | 2024-07-24 | | Last modified: | 2024-09-04 | | Method: | ELECTRON MICROSCOPY (3.61 Å) | | Cite: | Structural basis for intermodular communication in assembly-line polyketide biosynthesis.
Nat.Chem.Biol., 2024
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8TJP
 | | KS-AT core of 6-deoxyerythronolide B synthase (DEBS) Module 3 crosslinked with its elongation ACP partner | | Descriptor: | EryAII | | Authors: | Cogan, D.P, Soohoo, A.M, Chen, M, Brodsky, K.L, Liu, Y, Khosla, C. | | Deposit date: | 2023-07-23 | | Release date: | 2024-07-24 | | Last modified: | 2024-09-04 | | Method: | ELECTRON MICROSCOPY (3.71 Å) | | Cite: | Structural basis for intermodular communication in assembly-line polyketide biosynthesis.
Nat.Chem.Biol., 2024
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8TPX
 | | Crosslinked 6-deoxyerythronolide B synthase (DEBS) Module 3 in complex with antibody fragment 1B2: trans-oriented 1B2 and ACP | | Descriptor: | Antibody Fragment 1B2, Heavy Chain, Light Chain, ... | | Authors: | Cogan, D.P, Soohoo, A.M, Chen, M, Brodsky, K.L, Liu, Y, Khosla, C. | | Deposit date: | 2023-08-05 | | Release date: | 2024-08-07 | | Last modified: | 2024-09-04 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural basis for intermodular communication in assembly-line polyketide biosynthesis.
Nat.Chem.Biol., 2024
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8TJN
 | | Crosslinked 6-deoxyerythronolide B synthase (DEBS) Module 1 in complex with antibody fragment 1B2: Crosslinked State 1 | | Descriptor: | Antibody Fragment 1B2, Heavy Chain, Light Chain, ... | | Authors: | Cogan, D.P, Soohoo, A.M, Chen, M, Brodsky, K.L, Liu, Y, Khosla, C. | | Deposit date: | 2023-07-23 | | Release date: | 2024-07-24 | | Last modified: | 2024-09-04 | | Method: | ELECTRON MICROSCOPY (3.73 Å) | | Cite: | Structural basis for intermodular communication in assembly-line polyketide biosynthesis.
Nat.Chem.Biol., 2024
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8TPW
 | | Crosslinked 6-deoxyerythronolide B synthase (DEBS) Module 3 in complex with antibody fragment 1B2: cis-oriented 1B2 and ACP | | Descriptor: | Antibody Fragment 1B2, Heavy Chain, Light Chain, ... | | Authors: | Cogan, D.P, Soohoo, A.M, Chen, M, Brodsky, K.L, Liu, Y, Khosla, C. | | Deposit date: | 2023-08-05 | | Release date: | 2024-08-07 | | Last modified: | 2024-09-04 | | Method: | ELECTRON MICROSCOPY (3.46 Å) | | Cite: | Structural basis for intermodular communication in assembly-line polyketide biosynthesis.
Nat.Chem.Biol., 2024
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8EE1
 | | KS-AT didomain from module 2 of the 6-deoxyerythronolide B synthase in complex with antibody fragment AA5 | | Descriptor: | 6-deoxyerythronolide B synthase, AA5 antibody heavy chain, AA5 antibody light chain | | Authors: | Cogan, D.P, Brodsky, K.L, Guzman, K.M, Mathews, I.I, Khosla, C. | | Deposit date: | 2022-09-06 | | Release date: | 2023-05-31 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Discovery and Characterization of Antibody Probes of Module 2 of the 6-Deoxyerythronolide B Synthase.
Biochemistry, 62, 2023
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8EE0
 | | KS-AT didomain from module 2 of the 6-deoxyerythronolide B synthase in complex with antibody fragment 1B2 | | Descriptor: | 1B2 antibody heavy chain, 1B2 antibody light chain, 6-deoxyerythronolide B synthase | | Authors: | Cogan, D.P, Brodsky, K.L, Guzman, K.M, Mathews, I.I, Khosla, C. | | Deposit date: | 2022-09-06 | | Release date: | 2023-05-31 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Discovery and Characterization of Antibody Probes of Module 2 of the 6-Deoxyerythronolide B Synthase.
Biochemistry, 62, 2023
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