4S03
 
 | | Biphenylalanine modified threonyl-tRNA synthetase from Pyrococcus abyssi: I11BIF, Y79I, and F123A mutant | | 分子名称: | Threonine--tRNA ligase | | 著者 | Pearson, A.D, Mills, J.H, Song, Y, Nasertorabi, F, Han, G.W, Baker, D, Stevens, R.C, Schultz, P.G. | | 登録日 | 2014-12-30 | | 公開日 | 2015-03-18 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Transition states. Trapping a transition state in a computationally designed protein bottle.
Science, 347, 2015
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4S0L
 | | Biphenylalanine modified threonyl-tRNA synthetase from Pyrococcus abyssi: I11BIF, Y79V, and F123V mutant | | 分子名称: | Threonine--tRNA ligase | | 著者 | Pearson, A.D, Mills, J.H, Song, Y, Nasertorabi, F, Han, G.W, Baker, D, Stevens, R.C, Schultz, P.G. | | 登録日 | 2014-12-31 | | 公開日 | 2015-03-18 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Transition states. Trapping a transition state in a computationally designed protein bottle.
Science, 347, 2015
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4S02
 | | Biphenylalanine modified threonyl-tRNA synthetase from Pyrococcus abyssi: I11BIF, F42W, Y79A, and F123Y mutant | | 分子名称: | DI(HYDROXYETHYL)ETHER, Threonine--tRNA ligase | | 著者 | Pearson, A.D, Mills, J.H, Song, Y, Nasertorabi, F, Han, G.W, Baker, D, Stevens, R.C, Schultz, P.G. | | 登録日 | 2014-12-30 | | 公開日 | 2015-03-18 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Transition states. Trapping a transition state in a computationally designed protein bottle.
Science, 347, 2015
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4S0K
 | | Biphenylalanine modified threonyl-tRNA synthetase from Pyrococcus abyssi: 11BIF, 42F, 79V, and 123A mutant | | 分子名称: | DI(HYDROXYETHYL)ETHER, Threonine--tRNA ligase | | 著者 | Pearson, A.D, Mills, J.H, Song, Y, Nasertorabi, F, Han, G.W, Baker, D, Stevens, R.C, Schultz, P.G. | | 登録日 | 2014-12-31 | | 公開日 | 2015-03-18 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Transition states. Trapping a transition state in a computationally designed protein bottle.
Science, 347, 2015
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4S0I
 | | Biphenylalanine modified threonyl-tRNA synthetase from Pyrococcus abyssi: 11BIF, 42F, 79S, and 123A mutant | | 分子名称: | Threonine--tRNA ligase | | 著者 | Pearson, A.D, Mills, J.H, Song, Y, Nasertorabi, F, Han, G.W, Baker, D, Stevens, R.C, Schultz, P.G. | | 登録日 | 2014-12-31 | | 公開日 | 2015-03-18 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | | 主引用文献 | Transition states. Trapping a transition state in a computationally designed protein bottle.
Science, 347, 2015
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4IMZ
 | | Structural Basis of Substrate Specificity and Protease Inhibition in Norwalk Virus | | 分子名称: | Genome polyprotein, SODIUM ION, THIOCYANATE ION, ... | | 著者 | Prasad, B.V.V, Muhaxhiri, Z, Deng, L, Shanker, S, Sankaran, B, Estes, M.K, Palzkill, T, Song, Y. | | 登録日 | 2013-01-03 | | 公開日 | 2013-02-20 | | 最終更新日 | 2013-04-10 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural basis of substrate specificity and protease inhibition in norwalk virus.
J.Virol., 87, 2013
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4IN1
 | | Structural Basis of Substrate Specificity and Protease Inhibition in Norwalk Virus | | 分子名称: | 3C-like protease, SULFATE ION | | 著者 | Prasad, B.V.V, Muhaxhiri, Z, Deng, L, Shanker, S, Sankaran, B, Estes, M.K, Palzkill, T, Song, Y. | | 登録日 | 2013-01-03 | | 公開日 | 2013-02-20 | | 最終更新日 | 2020-01-29 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structural basis of substrate specificity and protease inhibition in norwalk virus.
J.Virol., 87, 2013
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4IMQ
 | | Structural Basis of Substrate Specificity and Protease Inhibition in Norwalk Virus | | 分子名称: | 3C-like protease, PEPTIDE INHIBITOR, syc8, ... | | 著者 | Prasad, B.V.V, Muhaxhiri, Z, Deng, L, Shanker, S, Sankaran, B, Estes, M.K, Palzkill, T, Song, Y. | | 登録日 | 2013-01-03 | | 公開日 | 2013-02-20 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural basis of substrate specificity and protease inhibition in norwalk virus.
J.Virol., 87, 2013
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4IN2
 | | Structural Basis of Substrate Specificity and Protease Inhibition in Norwalk Virus | | 分子名称: | C-like protease | | 著者 | Prasad, B.V.V, Muhaxhiri, Z, Deng, L, Shanker, S, Sankaran, B, Estes, M.K, Palzkill, T, Song, Y. | | 登録日 | 2013-01-03 | | 公開日 | 2013-02-20 | | 最終更新日 | 2013-04-10 | | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | | 主引用文献 | Structural basis of substrate specificity and protease inhibition in norwalk virus.
J.Virol., 87, 2013
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4INH
 | | Structural Basis of Substrate Specificity and Protease Inhibition in Norwalk Virus | | 分子名称: | DIMETHYL SULFOXIDE, Genome polyprotein, peptide inhibitor, ... | | 著者 | Prasad, B.V.V, Muhaxhiri, Z, Deng, L, Shanker, S, Sankaran, B, Estes, M.K, Palzkill, T, Song, Y. | | 登録日 | 2013-01-04 | | 公開日 | 2013-02-20 | | 最終更新日 | 2013-04-10 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural basis of substrate specificity and protease inhibition in norwalk virus.
J.Virol., 87, 2013
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6MO1
 | | Structure of dengue virus protease with an allosteric Inhibitor that blocks replication | | 分子名称: | 5-[4-(aminomethyl)phenyl]-6-[4-(furan-3-yl)phenyl]-N-[(piperidin-4-yl)methyl]pyrazin-2-amine, FLAVIVIRUS_NS2B/Peptidase S7 | | 著者 | Lin, Y.-L, Hua, Y, Nie, S, Wu, J, Wu, F, Huo, T, Yao, Y, Song, Y. | | 登録日 | 2018-10-03 | | 公開日 | 2019-05-15 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Discovery, X-ray Crystallography and Antiviral Activity of Allosteric Inhibitors of Flavivirus NS2B-NS3 Protease.
J.Am.Chem.Soc., 141, 2019
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6MO0
 | | Structure of dengue virus protease with an allosteric Inhibitor that blocks replication | | 分子名称: | 1-(4-{3-[4-(furan-3-yl)phenyl]-5-[(piperidin-4-yl)methoxy]pyrazin-2-yl}phenyl)methanamine, FLAVIVIRUS_NS2B/Peptidase S7 | | 著者 | Lin, Y.-L, Nie, S, Hua, Y, Wu, J, Wu, F, Huo, T, Yao, Y, Song, Y. | | 登録日 | 2018-10-03 | | 公開日 | 2019-05-22 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Discovery, X-ray Crystallography and Antiviral Activity of Allosteric Inhibitors of Flavivirus NS2B-NS3 Protease.
J. Am. Chem. Soc., 141, 2019
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6MO2
 | | Structure of dengue virus protease with an allosteric Inhibitor that blocks replication | | 分子名称: | 1-(4-{5-[(piperidin-4-yl)methoxy]-3-[4-(1H-pyrazol-4-yl)phenyl]pyrazin-2-yl}phenyl)methanamine, FLAVIVIRUS_NS2B/Peptidase S7 | | 著者 | Lin, Y.-L, Nie, S, Hua, Y, Wu, J, Wu, F, Huo, T, Yao, Y, Song, Y. | | 登録日 | 2018-10-03 | | 公開日 | 2019-05-15 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Discovery, X-ray Crystallography and Antiviral Activity of Allosteric Inhibitors of Flavivirus NS2B-NS3 Protease.
J.Am.Chem.Soc., 141, 2019
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2LP1
 | | The solution NMR structure of the transmembrane C-terminal domain of the amyloid precursor protein (C99) | | 分子名称: | C99 | | 著者 | Barrett, P.J, Song, Y, Van Horn, W.D, Hustedt, E.J, Schafer, J.M, Hadziselimovic, A, Beel, A.J, Sanders, C.R. | | 登録日 | 2012-01-30 | | 公開日 | 2012-06-06 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The amyloid precursor protein has a flexible transmembrane domain and binds cholesterol.
Science, 336, 2012
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2MV0
 | | Solution NMR Structure of Maltose-binding protein from Escherichia coli, Northeast Structural Genomics Consortium (NESG) Target ER690 | | 分子名称: | Maltose-binding periplasmic protein | | 著者 | Rossi, P, Lange, O.F, Sgourakis, N.G, Song, Y, Lee, H, Aramini, J.M, Ertekin, A, Xiao, R, Acton, T.B, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2014-09-18 | | 公開日 | 2014-12-10 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples.
Proc.Natl.Acad.Sci.USA, 109, 2012
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2NDJ
 | | Structural Basis for KCNE3 and Estrogen Modulation of the KCNQ1 Channel | | 分子名称: | Potassium voltage-gated channel subfamily E member 3 | | 著者 | Sanders, C.R, Van Horn, W.D, Kroncke, B.M, Sisco, N.J, Meiler, J, Vanoye, C.G, Song, Y, Nannemann, D.P, Welch, R.C, Kang, C, Smith, J, George, A.L. | | 登録日 | 2016-06-09 | | 公開日 | 2016-09-21 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis for KCNE3 modulation of potassium recycling in epithelia.
Sci Adv, 2, 2016
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5CB3
 | | Structural Insights into the Mechanism of Escherichia coli Ymdb | | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, O-acetyl-ADP-ribose deacetylase | | 著者 | Zhang, W, Wang, C, Song, Y, Shao, C, Zhang, X, Zang, J. | | 登録日 | 2015-06-30 | | 公開日 | 2015-11-04 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural insights into the mechanism of Escherichia coli YmdB: A 2'-O-acetyl-ADP-ribose deacetylase
J.Struct.Biol., 192, 2015
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5CMW
 | | Crystal structure of yeast Ent5 N-terminal domain-soaked in KI | | 分子名称: | Epsin-5, GLYCEROL, IODIDE ION | | 著者 | Zhang, F, Song, Y, Li, X, Teng, M.K. | | 登録日 | 2015-07-17 | | 公開日 | 2016-07-20 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural and functional insight into the N-terminal domain of the clathrin adaptor Ent5 from Saccharomyces cerevisiae
Biochem.Biophys.Res.Commun., 477, 2016
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5CN2
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5CB5
 | | Structural Insights into the Mechanism of Escherichia coli Ymdb | | 分子名称: | ACETATE ION, ADENOSINE-5-DIPHOSPHORIBOSE, O-acetyl-ADP-ribose deacetylase, ... | | 著者 | Zhang, W, Wang, C, Song, Y, Shao, C, Zhang, X, Zang, J. | | 登録日 | 2015-06-30 | | 公開日 | 2015-11-04 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural insights into the mechanism of Escherichia coli YmdB: A 2'-O-acetyl-ADP-ribose deacetylase
J.Struct.Biol., 192, 2015
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5CN1
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5CMY
 | | Crystal structure of yeast Ent5 N-terminal domain-native | | 分子名称: | Epsin-5, GLYCEROL | | 著者 | Zhang, F, Song, Y, Li, X, Teng, M.K. | | 登録日 | 2015-07-17 | | 公開日 | 2016-07-20 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Structural and functional insight into the N-terminal domain of the clathrin adaptor Ent5 from Saccharomyces cerevisiae
Biochem.Biophys.Res.Commun., 477, 2016
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5CMS
 | | Structural Insights into the Mechanism of Escherichia coli Ymdb | | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, O-acetyl-ADP-ribose deacetylase, SULFATE ION | | 著者 | Zhang, W, Wang, C, Song, Y, Shao, C, Zhang, X, Zang, J. | | 登録日 | 2015-07-17 | | 公開日 | 2015-11-04 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | | 主引用文献 | Structural insights into the mechanism of Escherichia coli YmdB: A 2'-O-acetyl-ADP-ribose deacetylase
J.Struct.Biol., 192, 2015
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5HS5
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5J08
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